LOCUS AJ515706 1203 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for squamous cell carcinoma antigen 1 (SERPINB3
gene).
ACCESSION AJ515706
VERSION AJ515706.1
KEYWORDS SCCA1 gene; SERPINB3 gene; squamous cell carcinoma antigen 1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1203)
AUTHORS Harrison T.J.
JOURNAL Submitted (12-NOV-2002) to the INSDC. Harrison T.J., Medicine,
University College London, Royal Free Campus, Rowland Hill Street,
London, NW3 3PF, UNITED KINGDOM.
REFERENCE 2
AUTHORS Moore P.L., Ong S., Harrison T.J.
TITLE Binding of HBV to cells is mediated by SCCA1 but does not require
the reactive site loop
JOURNAL J Biol Chem 278(47), 46709-46717(2003).
PUBMED 12975381
FEATURES Location/Qualifiers
source 1..1203
/db_xref="H-InvDB:HIT000248393"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_line="HepG2 (hepatocellular carcinoma)"
/cell_line="liver"
/db_xref="taxon:9606"
CDS 31..1203
/gene="SERPINB3"
/product="squamous cell carcinoma antigen 1"
/db_xref="GOA:P29508"
/db_xref="H-InvDB:HIT000248393.12"
/db_xref="HGNC:HGNC:10569"
/db_xref="InterPro:IPR000215"
/db_xref="InterPro:IPR023795"
/db_xref="InterPro:IPR023796"
/db_xref="InterPro:IPR036186"
/db_xref="InterPro:IPR042178"
/db_xref="InterPro:IPR042185"
/db_xref="PDB:2ZV6"
/db_xref="PDB:4ZK0"
/db_xref="PDB:4ZK3"
/db_xref="UniProtKB/Swiss-Prot:P29508"
/protein_id="CAD56658.1"
/translation="MNSLSEANTKFMFDLSQQFRKSKENNIFYSPISITSALGMVLLG
AKNNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELK
IATKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIK
NLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTS
FHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMR
ETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFV
EVTEEGAEAAAATAVVAFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP"
BASE COUNT 402 a 257 c 258 g 286 t
ORIGIN
1 ccagcacagt ggcggccgct cgagttcacc atgaattcac tcagtgaagc caacaccaag
61 ttcatgttcg acctgtccca acagttcaga aaatcaaaag agaacaacat cttctattcc
121 cctatcagca tcacatcagc attagggatg gtcctcttag gagccaaaaa caacactgca
181 caacagatta agaaggttct tcactttgat caagtcacag agaacaccac aggaaaagct
241 gcaacatatc atgttgatag gtcaggaaat gttcatcacc agtttcaaaa gcttctgact
301 gaattcaaca aatccactga tgcatatgag ctgaagatcg ccaccaagct cttcggagaa
361 aaaacgtatc tatttttaca ggaatattta gatgccatca agaaatttta ccagaccagt
421 gtggaatctg ttgattttgc aaatgctcca gaagaaagtc gaaagaagat taactcctgg
481 gtggaaagtc aaacgaatga aaaaattaaa aacctaattc ctgaaggtaa tattggcagc
541 aataccacat tggttcttgt gaacgcaatc tatttcaaag ggcagtggga gaagaaattt
601 aataaagaag atactaaaga ggaaaaattt tggccaaaca agaatacata caagtccata
661 cagatgatga ggcaatacac atcttttcat tttgcctcgc tggaggatgt acaggccaag
721 gtcctggaaa taccatacaa aggcaaagat ctaagcatga ttgtgttgct gccaaatgaa
781 atcgatggtc tccagaagct tgaagagaaa ctcactgctg agaaattgat ggaatggaca
841 agtttgcaga atatgagaga gacacgtgtc gatttacact tacctcggtt caaagtggaa
901 gagagctatg acctcaagga cacgttgaga accatgggaa tggtggatat cttcaatggg
961 gatgcagacc tctcaggcat gaccgggagc cgcggtctcg tgctatctgg agtcctacac
1021 aaggcctttg tggaggttac agaggaggga gcagaagctg cagctgccac cgctgtagta
1081 gcattcggat catcacctac ttcaactaat gaagagttcc attgtaatca ccctttccta
1141 ttcttcataa ggcaaaataa gaccaacagc atcctcttct atggcagatt ctcatccccg
1201 tag
//