LOCUS AJ515153 5727 bp mRNA linear HUM 21-OCT-2008
DEFINITION Homo sapiens mRNA for ADAMTS-20 protein, splice variant 1.
ACCESSION AJ515153
VERSION AJ515153.3
KEYWORDS ADAMTS-20 protein; alternative splicing;
metalloprotease-disintegrin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5727)
AUTHORS Llamazares M.
JOURNAL Submitted (01-NOV-2002) to the INSDC. Llamazares M., Bioquimica y
Biologia Molecular, Universidad de Oviedo, El Cristo., 33006,
SPAIN.
REMARK revised by author [04-FEB-2003]
REFERENCE 2
AUTHORS Llamazares M., Cal S., Quesada V., Lopez-Otin C.
TITLE Identification and characterization of ADAMTS-20 defines a novel
subfamily of metalloproteinases-disintegrins with multiple
thrombospondin-1 repeats and a unique GON domain
JOURNAL J Biol Chem 278(15), 13382-13389(2003).
PUBMED 12562771
COMMENT related sequence: AJ515154
FEATURES Location/Qualifiers
source 1..5727
/db_xref="H-InvDB:HIT000248386"
/organism="Homo sapiens"
/chromosome="12"
/map="12q12"
/mol_type="mRNA"
/tissue_type="liver"
/db_xref="taxon:9606"
CDS 1..5727
/gene="ADAMTS-20"
/product="ADAMTS-20 protein"
/function="metalloprotease-disintegrin"
/note="splice variant 1"
/db_xref="GOA:P59510"
/db_xref="H-InvDB:HIT000248386.14"
/db_xref="HGNC:HGNC:17178"
/db_xref="InterPro:IPR000884"
/db_xref="InterPro:IPR001590"
/db_xref="InterPro:IPR002870"
/db_xref="InterPro:IPR010294"
/db_xref="InterPro:IPR012314"
/db_xref="InterPro:IPR013273"
/db_xref="InterPro:IPR024079"
/db_xref="InterPro:IPR036383"
/db_xref="InterPro:IPR041645"
/db_xref="UniProtKB/Swiss-Prot:P59510"
/protein_id="CAD56159.3"
/translation="MWVAKWLTGLLYHLSLFITRSWEVDFHPRQEALVRTLTSYEVVI
PERVNEFGEVFPQSHHFSRQKRSSEALEPMPFRTHYRFTAYGQLFQLNLTADASFLAA
GYTEVHLGTPERGAWESDAGPSDLRHCFYRGQVNSQEDYKAVVSLCGGLVGTFKGQNG
EYFLEPIMKADGNEYEDGHNKPHLIYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTY
SNMNEDLNVMKERVLGHTSKNVPLKDERRHSRKKRLISYPRYIEIMVTADAKVVSAHG
SNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVINFDGATTLKNFC
SWQQTQNDLDDVHPSHHDTAVLITRYDICSSKEKCNMLGLSYLGTICDPLQSCFINEE
KGLISAFTIAHELGHTLGVQHDDNPRCKEMKVTKYHVMAPALSFHMSPWSWSNCSRKY
VTEFLETGYGECLLDKPDEEIYNLPSELPGSRYDGNKQCELAFGPGSQMCPHINICMH
LWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCRHGLCVNKETETRPVNGEWGPWEPYS
SCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSD
FNGKHLDISGIPSNVRWLPRYSGVGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTE
THDICVQGQCMAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHYGYNVVVKI
PAGATNVDIRQYSYSGQPDDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTVIEYSG
SNNAVERINSTNRQEKEILIEVLCVGNLYNPDVHYSFNIPLEERSDMFTWDPYGPWEG
CTKMCQGLQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRWHVIGKSEC
SSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGNCVFTRWHYSE
WSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRVTRENCNEFSCPSWAASEWSE
CLVTCGKGTKQRQVWCQLNVDHLSDGFCNSSTKPESLSPCELHTCASWQVGPWGPCTT
TCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISKLETALLPTV
LIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRPAEIWDCFT
PCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACP
PAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCSSSCSG
GLQHRAVVCQDENGQSASYCDAASKPPELQQCGPGPCPQWNYGNWGECSQTCGGGIKS
RLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPWTSCSASCGKGRK
YREVFCIDQFQRKLEDTNCSQVQKPPTHKACRSVRCPSWKANSWNECSVTCGSGVQQR
DVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQDCVQHKGMERGRLNCSTSCERKDSHQ
RMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPCNYIVVTADSSQCANNCGFSYRQRI
TYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQCINSCLHLATWKVGKWSKCSVTC
GIGIMKRQVKCITKHGLSSDLCLNHLKPGAQKKCYANDCKSFTTCKEIQVKNHIRKDG
DYYLNIKGRIIKIYCADMYLENPKEYLTLVQGEENFSEVYGFRLKNPYQCPFNGSRRE
DCECDNGHLAAGYTVFSKIRIDLTSMQIKATDLLFSKTIFGNAVPFATAGDCYSAFRC
PQGQFSINLSGTGMKISSTAKWLTQGSYTSVSIRRSQDGTRFFGKCGGYCGKCLPHMT
TGLPIQVI"
BASE COUNT 1728 a 1162 c 1332 g 1505 t
ORIGIN
1 atgtgggtgg ccaagtggct gactgggctg ctctaccatc tctcgctctt catcaccagg
61 tcttgggaag ttgacttcca ccccaggcaa gaagccctgg tgaggacact gacctcctac
121 gaagtagtga tccccgagcg ggtcaatgag tttggagaag tgttccctca gagccaccac
181 ttcagccggc agaaacgcag ctccgaggcg ctggaaccca tgccgttccg aacccactat
241 cgcttcactg cctacgggca gctcttccag ctgaacctga ccgccgatgc atcctttctg
301 gccgccggct acaccgaggt gcacttggga accccggagc gcggggcctg ggagagcgac
361 gcagggccct cggacctgcg ccactgcttc taccgcggcc aggtcaactc acaggaggat
421 tacaaggccg tcgtcagctt atgcggaggc ctggtgggaa catttaaagg acagaacggt
481 gaatatttct tagaacctat aatgaaggca gatgggaatg aatatgaaga tggtcacaac
541 aagccacatc ttatatacag acaagactta aataactctt ttctgcagac tctgaagtat
601 tgcagtgtgt cagaaagtca aataaaggaa accagtttac cctttcatac ctacagcaac
661 atgaatgaag atcttaatgt aatgaaagaa agagttttag gacacacatc aaaaaatgta
721 ccattgaaag atgaaagaag acattccagg aaaaaacgtc ttatatcata tccaagatac
781 attgaaatta tggttacagc tgatgctaaa gtggtttctg ctcatggatc gaatttgcaa
841 aactatatac tgactctaat gtcaattgtt gcaacaatct acaaagatcc aagtattgga
901 aatttgatac acatagtagt ggtaaaatta gttatgattc accgtgagga ggaaggacca
961 gtcattaatt ttgatggtgc taccacatta aagaactttt gttcatggca acaaactcag
1021 aatgaccttg atgatgttca cccttcccac catgacactg ctgttcttat cactaggtat
1081 gatatttgtt catctaaaga gaaatgtaac atgttaggtt tatcatattt aggtaccata
1141 tgtgatcctt tacaaagctg ctttattaat gaagaaaaag gactcatttc tgcttttact
1201 atagcccatg agcttgggca cacacttggt gttcaacatg atgataatcc tagatgtaaa
1261 gaaatgaaag ttacaaagta tcatgtaatg gcccccgctt taagttttca catgagtcct
1321 tggagctggt caaactgtag tcggaaatat gttactgaat tcctagagac tggttacggg
1381 gaatgtcttc ttgacaaacc agatgaagaa atatataatc tgccttcaga acttcctgga
1441 tcacgatatg atggaaacaa gcagtgtgag cttgcgtttg gtcctgggtc acaaatgtgt
1501 ccccatataa atatatgcat gcatctgtgg tgcacaagca cagaaaagct tcacaaaggc
1561 tgtttcactc aacacgtgcc accagcagat ggaacagact gcggtcctgg aatgcattgc
1621 cgtcatgggc tatgtgtaaa caaagaaacg gaaacacgtc ctgtaaatgg tgaatgggga
1681 ccatgggaac cttacagttc ttgttcaaga acatgtggag gcggaatcga aagtgcaacc
1741 aggcgctgta atcgtcctga gccaagaaac ggaggaaatt actgtgtggg ccgcaggatg
1801 aaatttcgat catgtaatac tgattcatgt ccaaaaggca cacaagactt tcgagagaag
1861 cagtgctctg attttaatgg taaacatttg gacatcagtg gcattccctc taatgtgagg
1921 tggcttccaa gatacagtgg cgttggcaca aaggatcgtt gtaaactcta ttgtcaggtt
1981 gctggaacca attatttcta cctattgaag gatatggttg aagatggtac tccttgtgga
2041 actgaaactc atgacatctg tgttcaaggc cagtgtatgg cagctggttg tgatcacgtg
2101 ttaaactcca gtgccaagat agacaaatgt ggagtgtgtg gtggggacaa ctcttcatgc
2161 aagacaataa caggtgtctt caacagttct cattatggtt ataatgttgt tgtaaagatt
2221 cccgcaggag caacaaacgt tgacattcgt cagtacagct attctggaca accagatgac
2281 agttaccttg cattatctga cgctgaaggg aattttcttt tcaatggaaa ttttcttcta
2341 agtacgtcaa aaaaagaaat caatgtgcaa ggaactgtta ttgaatacag tggatcaaat
2401 aacgcagttg aaagaattaa tagtactaat cgacaagaga aagaaattct tattgaggtg
2461 ttgtgtgtgg gtaatttata caaccctgat gtacattatt ccttcaatat ccctttggaa
2521 gagaggagtg acatgttcac atgggacccc tatggaccat gggaaggctg taccaaaatg
2581 tgtcaaggtc ttcagcgaag aaacataact tgcatacata agagtgatca tagtgttgtg
2641 tctgataaag aatgtgacca cttgccactt ccatcatttg ttactcaaag ttgcaataca
2701 gactgtgaac taaggtggca tgttattggc aaaagtgaat gttcatccca atgtggtcaa
2761 ggatatagaa ccttggacat ccattgcatg aagtattcca ttcatgaagg acagactgtt
2821 caagttgatg accactactg tggtgaccag cttaaacctc ctacccaaga actatgccat
2881 ggtaactgtg tcttcacaag atggcattat tcagaatggt ctcagtgttc caggagttgt
2941 ggaggagggg aaaggtctcg agaatcttat tgtatgaata actttggcca tcgtcttgct
3001 gacaatgaat gccaagaact gtcccgagtg acgagagaga attgcaatga attttcctgt
3061 cccagttggg ctgctagtga atggagcgag tgccttgtta catgtggtaa aggaacaaag
3121 cagcggcagg tatggtgtca gctgaatgta gatcacttga gtgatggctt ctgtaattca
3181 agtaccaaac ctgaatctct gagtccatgt gaacttcata catgtgcttc ctggcaagta
3241 ggaccatggg gtccttgcac aaccacatgt ggacatgggt atcagatgcg agatgttaaa
3301 tgtgtcaatg agctagctag tgcagtgtta gaggacacag aatgccatga agctagtcgc
3361 cccagtgaca gacagagctg tgtacttaca ccttgctcat ttatttctaa acttgagacc
3421 gctttattac caactgttct cataaaaaag atggcacaat ggcgacatgg ttcttggacc
3481 ccatgctccg tatcttgtgg aagaggtact caagcccgct atgtaagctg tcgtgatgct
3541 cttgatagaa tagcagatga atcatattgt gcccacttac cccgacctgc tgaaatatgg
3601 gactgtttta ccccttgtgg agagtggcaa gcaggggatt ggtcaccctg ttcagcttcc
3661 tgtggccatg gaaaaacaac tcgacaagtt ttatgcatga actaccatca gccaattgat
3721 gagaattact gtgatcctga agttcgccct ttgatggaac aggaatgtag cctggcagcc
3781 tgccctcctg cacacagcca ctttcctagt tcccctgtgc agccaagcta ttatctaagc
3841 acgaatttgc cattaactca aaaacttgaa gataatgaaa atcaggtggt ccatccatca
3901 gtcagaggaa accagtggag aaccggacca tggggacagt gctccagcag ttgttctgga
3961 ggtcttcagc atagggctgt ggtctgccag gatgaaaatg gacaaagtgc tagttactgc
4021 gatgcagcct ccaagcctcc agagttacag caatgtggtc cagggccttg tccacagtgg
4081 aactacggaa attggggaga atgttcacaa acatgtggag gaggaataaa atcaagactt
4141 gtaatatgtc aatttcccaa tggccaaata ttagaagatc acaactgtga aattgtaaac
4201 aagccaccta gcgtaataca gtgtcatatg catgcttgcc ctgctgatgt gtcatggcat
4261 caggaaccat ggacatcgtg ctcagcttct tgtggtaaag gtagaaagta ccgtgaagtg
4321 ttttgcattg accaattcca aaggaaatta gaagacacaa attgcagtca agtacagaaa
4381 cctccaactc acaaagcctg tagatctgtc agatgccctt catggaaagc caatagctgg
4441 aatgagtgct ctgtgacctg tggctctgga gttcagcaga gggatgtata ctgcagactg
4501 aaaggtgttg gtcaggtggt tgaagaaatg tgtgatcagt ccacccgacc ttgttctcag
4561 aggcgatgtt ggagtcagga ctgtgtgcag cacaagggga tggaaagagg gaggctgaat
4621 tgttcaacat catgtgagag aaaagattca catcaacgaa tggagtgcac agataaccaa
4681 atcagacaag tgaatgaaat agtctataat tcttcaacca tatctcttac atccaagaat
4741 tgcaggaacc ctccttgcaa ttacattgtg gtaacagcag actcatcaca gtgtgcaaac
4801 aactgtggat ttagttacag acaaaggatt acatattgca ccgagatccc atctactaag
4861 aaacataagc tccatcgact tcggcctata gtttatcaag aatgccctgt ggtgccttcc
4921 tctcaggttt accaatgcat taacagctgt ttgcatttgg ccacttggaa agttggaaaa
4981 tggagcaagt gctcagtgac ttgtggaatt gggataatga agagacaagt gaaatgcatt
5041 accaaacatg gtttgtccag tgacttatgt ttaaaccatt taaaaccagg tgctcaaaag
5101 aaatgttatg ccaatgactg taaatcattt accacctgca aagaaattca agtgaaaaac
5161 cacattagaa aggatggtga ctattacctt aacattaagg gaagaataat aaagatttat
5221 tgtgcagaca tgtacttgga gaaccctaag gaatatttaa cactggtcca aggtgaagaa
5281 aacttttctg aagtgtatgg ctttaggcta aaaaatccat atcaatgtcc ttttaatggg
5341 agtagaaggg aagactgtga atgtgacaat ggacacttag ctgctggata cactgttttc
5401 agcaaaataa gaattgatct cacttccatg caaattaaag ctacggacct tcttttttcc
5461 aaaacaatat ttggaaatgc agttccattt gccacagctg gagattgcta cagtgctttc
5521 agatgcccac agggacagtt tagcattaat ttgtcaggaa ctgggatgaa gatatccagc
5581 acagcaaagt ggctcactca ggggagttat acctctgtca gcatacgaag atcacaggat
5641 ggaactagat ttttcggcaa atgtggaggg tactgtggaa agtgtcttcc tcacatgact
5701 actggtctcc caattcaagt catatga
//