LOCUS AJ459824 5538 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for AHI1 protein, splice variant 1.
ACCESSION AJ459824
VERSION AJ459824.1
KEYWORDS AHI1 gene; alternative spliciing; splice variant 1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5538)
AUTHORS Close J.P.
JOURNAL Submitted (07-MAY-2002) to the INSDC. Close J.P., Department of
Molecular Haematology, King's College London, GKT School of
Medicine, King's Denmark Hill Campus, Bessemer Road, London, SE5
9PJ, UNITED KINGDOM.
REFERENCE 2
AUTHORS Close J.P., Game I.G., Clark B., Thein S.L.
TITLE An integrated physical and transcript map of human 6q23
encompassing a quantitative trait loci for foetal haemaglobin
expression.
JOURNAL Thesis (2002), Department of Clinical medicine, University of
Oxford, Oxford, United Kingdom.
COMMENT alternative splice variant sequences: AJ459825
FEATURES Location/Qualifiers
source 1..5538
/db_xref="H-InvDB:HIT000248084"
/organism="Homo sapiens"
/chromosome="6"
/map="6q23"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 280..3870
/gene="AHI1"
/product="AHI1 protein"
/note="alternative splice variant 1"
/db_xref="GOA:Q8N157"
/db_xref="H-InvDB:HIT000248084.14"
/db_xref="HGNC:HGNC:21575"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR001680"
/db_xref="InterPro:IPR015943"
/db_xref="InterPro:IPR017986"
/db_xref="InterPro:IPR035832"
/db_xref="InterPro:IPR036028"
/db_xref="InterPro:IPR036322"
/db_xref="PDB:4ESR"
/db_xref="UniProtKB/Swiss-Prot:Q8N157"
/protein_id="CAD30871.1"
/translation="MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENI
SPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLR
NTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTK
PQPGVDHQKSEKANEGREETDLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTY
FPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDS
HQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVY
PKCLLDDDLVLGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYY
EKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEIL
DFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSP
LSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSYRSMMALQEEKGKPVHCERH
HESSSVDTEPGLEESKEVIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRIL
AAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWK
NEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQF
DVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEF
KGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPCGT
FLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPIL
LYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESS
STKMQLVKQRLETVTEVIRSCAAKVNKNLSFTSPPAVSSQQSKLKQSNMLTAQEILHQ
FGFTQTGIISIERKPCNHQVDTAPTVVALYDYTANRSDELTIHRGDIIRVFFKDNEDW
WYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSPAPQKQSIN
KNKSQDFRLGSESMTHSEMRKEQSHEDQGHIMDTRMRKNKQAGRKVTLIE"
regulatory 4051..4057
/gene="AHI1"
/note="alternative"
/regulatory_class="polyA_signal_sequence"
regulatory 5506..5511
/gene="AHI1"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1863 a 1021 c 1139 g 1515 t
ORIGIN
1 gcggcacaga gccgcggctt gctttcagga cacgggtcgc tggcgggtta ggtggctgcg
61 tggccgcctc acttcgcgca cgcgccgcta ggctggggga gttgatttgc actgctccgg
121 gtgtcggctc cggcgggacg ggcggttctg cgtacccctc tccagtgtca acctggggct
181 gaatcttcaa cctgtcaaag ccttcttaat tatgtctgag aaaaggatcc tgattgagtc
241 aatgctttgc attctcagtc ctctgcataa agctgagaga tgcctacagc tgagagtgaa
301 gcaaaagtaa aaaccaaagt tcgctttgaa gaattgctta agacccacag tgatctaatg
361 cgtgaaaaga aaaaactgaa gaaaaaactt gtcaggtctg aagaaaacat ctcacctgac
421 actattagaa gcaatcttca ctatatgaaa gaaactacaa gtgatgatcc cgacactatt
481 agaagcaatc ttccccatat taaagaaact acaagtgatg atgtaagtgc tgctaacact
541 aacaacctga agaagagcac gagagtcact aaaaacaaat tgaggaacac acagttagca
601 actgaaaatc ctaatggtga tgctagtgta gaggaagaca aacaaggaaa gccaaataaa
661 aaggtgataa agacggtgcc ccagttgact acacaagacc tgaaaccgga aactcctgag
721 aataaggttg attctacaca ccagaaaaca catacaaagc cacagccagg cgttgatcat
781 cagaaaagtg agaaggcaaa tgagggaaga gaagagactg atttagaaga ggatgaagaa
841 ttgatgcaag catatcagtg ccatgtaact gaagaaatgg caaaggagat taagaggaaa
901 ataagaaaga aactgaaaga acagttgact tactttccct cagatacttt attccatgat
961 gacaaactaa gcagtgaaaa aaggaaaaag aaaaaggaag ttccagtctt ctctaaagct
1021 gaaacaagta cattgaccat ctctggtgac acagttgaag gtgaacaaaa gaaagaatct
1081 tcagttagat cagtttcttc agattctcat caagatgatg aaataagctc aatggaacaa
1141 agcacagaag acagcatgca agatgataca aaacctaaac caaaaaaaac aaaaaagaag
1201 actaaagcag ttgcagataa taatgaagat gttgatggtg atggtgttca tgaaataaca
1261 agccgagata gcccggttta tcccaaatgt ttgcttgatg atgaccttgt cttgggagtt
1321 tacattcacc gaactgatag acttaagtca gattttatga tttctcaccc aatggtaaaa
1381 attcatgtgg ttgatgagca tactggtcaa tatgtcaaga aagatgatag tggacggcct
1441 gtttcatctt actatgaaaa agagaatgtg gattatattc ttcctattat gacccagcca
1501 tatgatttta aacagttaaa atcaagactt ccagagtggg aagaacaaat tgtatttaat
1561 gaaaattttc cctatttgct tcgaggctct gatgagagtc ctaaagtcat cctgttcttt
1621 gagattcttg atttcttaag cgtggatgaa attaagaata attctgaggt tcaaaaccaa
1681 gaatgtggct ttcggaaaat tgcctgggca tttcttaagc ttctgggagc caatggaaat
1741 gcaaacatca actcaaaact tcgcttgcag ctatattacc cacctactaa gcctcgatcc
1801 ccattaagtg ttgttgaggc atttgaatgg tggtcaaaat gtccaagaaa tcattaccca
1861 tcaacactgt acgtaactgt aagaggactg aaagttccag actgtataaa gccatcttac
1921 cgctctatga tggctcttca ggaggaaaaa ggtaaaccag tgcattgtga acgtcaccat
1981 gagtcaagct cagtagacac agaacctgga ttagaagagt caaaggaagt aataaagtgg
2041 aaacgactcc ctgggcaggc ttgccgtatc ccaaacaaac acctcttctc actaaatgca
2101 ggagaacgag gatgtttttg tcttgatttc tcccacaatg gaagaatatt agcagcagct
2161 tgtgccagcc gggatggata tccaattatt ttatatgaaa ttccttctgg acgtttcatg
2221 agagaattgt gtggccacct caatatcatt tatgatcttt cctggtcaaa agatgatcac
2281 tacatcctta cttcatcatc tgatggcact gccaggatat ggaaaaatga aataaacaat
2341 acaaatactt tcagagtttt acctcatcct tcttttgttt acacggctaa attccatcca
2401 gctgtaagag agctagtagt tacaggatgc tatgattcca tgatacggat atggaaagtt
2461 gagatgagag aagattctgc catattggtc cgacagtttg atgttcacaa aagttttatc
2521 aactcacttt gttttgatac tgaaggtcat catatgtatt caggagattg tacaggggtg
2581 attgttgttt ggaataccta tgtcaagatt aatgatttgg aacattcagt gcaccactgg
2641 actataaata aggaaattaa agaaactgag tttaagggaa ttccaataag ttatttggag
2701 attcatccca atggaaaacg tttgttaatc cataccaaag acagtacttt gagaattatg
2761 gatctccgga tattagtagc aaggaagttt gtaggagcag caaattatcg ggagaagatt
2821 catagtactt tgactccatg tgggactttt ctgtttgctg gaagtgagga tggtatagtg
2881 tatgtttgga acccagaaac aggagaacaa gtagccatgt attctgactt gccattcaag
2941 tcacccattc gagacatttc ttatcatcca tttgaaaata tggttgcatt ctgtgcattt
3001 gggcaaaatg agccaattct tctgtatatt tacgatttcc atgttgccca gcaggaggct
3061 gaaatgttca aacgctacaa tggaacattt ccattacctg gaatacacca aagtcaagat
3121 gccctatgta cctgtccaaa actaccccat caaggctctt ttcagattga tgaatttgtc
3181 cacactgaaa gttcttcaac gaagatgcag ctagtaaaac agaggcttga aactgtcaca
3241 gaggtgatac gttcctgtgc tgcaaaagtc aacaaaaatc tctcatttac ttcaccacca
3301 gcagtttcct cacaacagtc taagttaaag cagtcaaaca tgctgaccgc tcaagagatt
3361 ctacatcagt ttggtttcac tcagaccggg attatcagca tagaaagaaa gccttgtaac
3421 catcaggtag atacagcacc aacggtagtg gctctttatg actacacagc gaatcgatca
3481 gatgaactaa ccatccatcg cggagacatt atccgagtgt ttttcaaaga taatgaagac
3541 tggtggtatg gcagcatagg aaagggacag gaaggttatt ttccagctaa tcatgtggct
3601 agtgaaacac tgtatcaaga actgcctcct gagataaagg agcgatcccc tcctttaagc
3661 cctgaggaaa aaactaaaat agaaaaatct ccagctcctc aaaagcaatc aatcaataag
3721 aacaagtccc aggacttcag actaggctca gaatctatga cacattctga aatgagaaaa
3781 gaacagagcc atgaggacca aggacacata atggatacac ggatgaggaa gaacaagcaa
3841 gcaggcagaa aagtcactct aatagagtaa agaattgaag aaaagttaag agctgccgaa
3901 atgcacagag gtgaaaatga caaaccaaat ggaatttctc ttcagagttc agaattttca
3961 gatactaagg aggaagaaag gatccactac ttcttgttct tatgaatgac tctagaaaaa
4021 tcagaatcaa gttgtgggtg gaaaaatcaa cgtggccttt gagttcagtt gttataaacc
4081 attgtgacta ttgttggtca aagtattggt acttatattg ttagtaattg catcataatt
4141 acattaccag tgttggaaaa ctaatgaaga aaacactgta attgctactc agcaaatgtg
4201 aataaaaggt gtttgcgtta ttaggatgtc tgttaagtaa tcatttaata ttattatatt
4261 ggtaatggtt gtatgtgtga tgctatgccc agaatatgaa gtatctgttt ttgaaattca
4321 ctttatttaa aagataagca gctgactggg cacggtgcct catgcctgta atcctagcac
4381 cttgggaggc tgaggcaggt ggatcaccta aggtcaggag ttcaacaaca ccagcctgac
4441 caacatggtg aaaccccatc tctactaaaa atacaaaaat cagccgggtc tcatggcagg
4501 cacctgtaat cccatctact gaggcaggag aattgcttga cccaggaggc agaggttgca
4561 gtgagccaag atcacgccat tgcactccag cctgggggac agagcaagac tctatctcca
4621 aaaaacaaaa aagataagca gctttagaat atggcgcatt caaaacagtc tcagtaacaa
4681 agacattaaa agaaaacaat ttactttcta attaaaattt tgtgtttctt aagatcaaat
4741 catataggta acttcataga cctaaattaa aagtgatttt tggctggact ggcaacaatg
4801 ttcccaatgt ctttactttt taaaaaaggc ttttcatatt taagcacata cctattttgt
4861 agacttacat tgtttaatat ttattttaat cttaatattt ttacattatt atattgcatt
4921 atttattttt tctaagttcc agaataatag tgtcattatt atagactata tgttttgaag
4981 tttgatatta taatgggata ttcatttttt gttcttttct tgactccttt ctcaagtgtg
5041 tgataaggtc tgctgataaa atatttaacc ccaagaaagt gaaaactaat ataaaattag
5101 aaagacctat ccaaattaga cagtcaattc cattaaaata agaagtgaga aaaacaatgt
5161 tgggcattga ggtgtaaatt ttgcccagat gtatacccag tgtgaaatat cttctaataa
5221 aaatatattt ggctcttatc cctgcacatg tagaggcata aaaattggta aacatgtccc
5281 gctgtgtaga actttaaaaa aaaggcattt ttgaaagtgt tgagtggcac tgataactgg
5341 tgaagcctac agccatccgc ccaaaagtct gttctgatgg cactgagttt tcattgttct
5401 ggatgtataa gtctgtgtgt caggtacagc tgggcccagc cagcttgagt cactcttgta
5461 caagcttgtt tttttctgtc ttgtgaatgc acttgataat ttaaaaataa aaatatctgt
5521 ttctctgcaa aaaaaaaa
//