LOCUS AJ421269 4114 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for RCC1-like protein (TD-60 gene).
ACCESSION AJ421269
VERSION AJ421269.1
KEYWORDS chromosome condensation regulator; RCC1-like protein; TD-60 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4114)
AUTHORS Kleman J.P.
JOURNAL Submitted (29-NOV-2001) to the INSDC. Kleman J.P., IBS Jean-Pierre
Ebel, Commissariat a l'energie atomique, 41 rue J. Horowitz, 38027
Grenoble cedex 1, FRANCE.
REFERENCE 2 (bases 1 to 4114)
AUTHORS Mollinari C., Reynaud C., Martineau-Thuillier S., Monier S.,
Kieffer S., Garin J., Andreassen P.R., Boulet A., Goud B.,
Kleman J.-P., Margolis R.L.
TITLE The mammalian passenger protein TD-60 is an RCC1 family member with
an essential role in prometaphase to metaphase progression
JOURNAL Dev. Cell 5(2), 295-307(2003).
PUBMED 12919680
COMMENT Corresponding human genomic region: AC004824
FEATURES Location/Qualifiers
source 1..4114
/db_xref="H-InvDB:HIT000247901"
/organism="Homo sapiens"
/chromosome="X"
/mol_type="mRNA"
/sex="Female"
/cell_line="HeLa"
/cell_type="Epithelial carcinoma"
/db_xref="taxon:9606"
5'UTR 1..235
/gene="TD-60"
CDS 236..1804
/gene="TD-60"
/product="RCC1-like protein"
/function="chromosome condensation regulator involved in
cytokinesis"
/db_xref="GOA:Q9P258"
/db_xref="H-InvDB:HIT000247901.14"
/db_xref="HGNC:HGNC:30297"
/db_xref="InterPro:IPR000408"
/db_xref="InterPro:IPR009091"
/db_xref="PDB:5GWN"
/db_xref="UniProtKB/Swiss-Prot:Q9P258"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAD13148.1"
/translation="MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSS
SSGGGSSGDEDGLELDGAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKC
KGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA
HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALT
ETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLY
SFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRD
VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAG
YTCSFAVSEVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADEST
ISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEK
EKIKKLPEYNPRTL"
3'UTR 1805..4114
/gene="TD-60"
BASE COUNT 874 a 1058 c 1156 g 1026 t
ORIGIN
1 ttgatgaaac gcggatccag acgctgcgtt tgctggcttt gatgaaacgc acatgtgttt
61 ctgttttgtg ttgtagcatt tgttctggaa gctcgtattt acattttaag tgtatctggt
121 gagtgggctg gagccctcgt ctgggccgga aaaaaaaaag ccctccgatc cgtcttttag
181 ttgcttctct tccttttttc tctccggttt ctcatcactc caaccagccg cgaccatgcc
241 caggaagaag gcggcggcgg cggcctggga ggagccgagc tcgggcaacg gcactgcccg
301 cgccgggccc aggaaacgcg gcggcccggc gggcaggaag cgcgagcggc ccgagcgctg
361 cagtagcagc agcggcggcg gcagcagcgg cgacgaggac ggcctggagc tcgacggggc
421 ccccggcggg ggcaagcgcg cggcgcggcc ggcgacagca ggcaaggcgg gcggcgcggc
481 cgtggtcatc accgaacccg agcacaccaa ggagcgcgtc aaacttgaag ggtcaaagtg
541 caaagggcag cttttgattt ttggggcaac caactgggac ttgattggtc gaaaagaagt
601 gcctaaacag caagctgctt accgcaatct cggtcagaat ttgtgggggc cccacagata
661 tgggtgcctg gcgggggtcc gggtgcggac agtggtctcg ggctcgtgtg ctgcacacag
721 cctcctcatc accacggaag ggaagctgtg gagctggggt cgaaatgaga aggggcagct
781 gggacatggt gacaccaaga gagtagaagc ccctagactc atcgagggtc ttagccacga
841 agtgattgtg tctgcagcat gtgggcggaa ccacaccttg gccttgacgg aaacgggctc
901 cgtgtttgcg tttggggaaa acaagatggg gcagctgggc cttggcaacc agacagacgc
961 tgttcccagc cccgcgcaga taatgtacaa cggccagcca attaccaaaa tggcctgtgg
1021 ggctgaattc agtatgataa tggactgcaa aggaaacctc tattcctttg ggtgccctga
1081 atatggtcag ctgggacaca actcagatgg gaagttcatc gcccgggcac agcggataga
1141 gtacgactgt gaactagttc cccggcgagt ggccatcttc attgagaaga cgaaagatgg
1201 acagattctg cctgtaccaa acgtggttgt acgagacgtg gcctgtggcg ctaaccacac
1261 gctggtcctg gactcccaga agcgagtctt ctcctggggc tttggtggct atggccggct
1321 gggccacgca gagcagaagg atgagatggt cccccgcctg gtgaagctgt ttgacttccc
1381 tgggcgtggg gcttcccaga tctatgctgg ttacacctgc tcctttgctg tcagtgaagt
1441 gggtggtctg tttttctggg gggccaccaa cacctcccgt gaatctacca tgtacccaaa
1501 agcagtgcag gacctctgcg gctggagaat tcggagcctg gcttgtggga agagcagcat
1561 cattgtggcc gccgatgaga gcaccatcag ctggggtccg tcaccgacct ttggggaact
1621 gggctacggg gaccacaagc ccaagtcttc cactgcagcc caggaggtaa agactctgga
1681 tggcattttc tcagagcagg tcgccatggg ctactcacac tccttggtga tagcaagaga
1741 tgaaagtgag actgagaaag agaagatcaa gaaactgcca gaatacaacc cccgaaccct
1801 ctgatgctcc cggagactcc tccgactcca cacctctcgc ggcagctgtc atttccatgt
1861 gcactgggac gggaagtcaa acgaggaatt taaaaaagca aaagttgacc gaaggtgcat
1921 ttttgtttag actccctgag gttccgtttt acacatgatc caacgttaac tacctttttt
1981 tctgtatgct ttccaaagtc cttttttttc ccttaatgtt gaattaaaat acttgctcat
2041 agttgattta ccattcctac aaaagaggca gaaactttga gcaatctagg tttttttttt
2101 tttttttaag ttttttcttt cttcctttcc tgaatacact ccccaaaaca cccctttcca
2161 gttacaatta gcatcgtgat ccaagcagat gccacatgga agaggaatcg ccatttactc
2221 agaaaaaatg tcccttacag gaaccggcag cagctaggca gtcaccggcc cgcctccatc
2281 caaaatcacg ctcgcgtgct tcggaagcat ccgggtcact ccttctccgc tttttcttgc
2341 agatgggcct aggccggtgt cggttctgtt tctccccttg gctgcctgta cgcccacagc
2401 cttctggctg cgacattata gaatcggccg tgtcccccct ggtgggggat tggggatctg
2461 tgtttagcca tttatatcta ctttagctgt taaagaggtc caaatgaaaa tcaggtgatt
2521 gtggaaccat ggggacttgg gggtggggca gaggtgggaa catttgtatc agttgagtca
2581 gcttggtggc tccctgtgga gccagggctg agccttgtca cgcgcactcg ccaattaaga
2641 gatggaccag ccagcagtca agtgcattct ccagtccttg caagaaggat cagccctttc
2701 tgtgccagcc tcgatcgcct tgtgctttgg tctctttttc tcccccccgc ctggatcctg
2761 cctcgcgcgg gccgtcctgt tgctgagact cggggtaccg ttctgctgac ccagctccct
2821 ttagtcacgt ttgcttggct ctggtaccaa atagttggga ttaccgaaga gtccccttcc
2881 ttgcgtgtca gcacggatgc tgtgactgcc acctgcgtcc tcgtcaagtg cccgagctcg
2941 ccgccgtgtg tgctgcgctg agtgagttat gaggtgcctt tcccggaacc ctcctctcgc
3001 ctggacccaa gagaggcgac agctgtggct ggggctcttg gtttccagag ggtctggact
3061 ggtttgggtg ctttaaaata gatatttagt tcagtggtgc ttatggggga gatgggacta
3121 gaacttaagt gtgagacttg ggtggatggg aaagttaaat attggtctct tcaagttttt
3181 tttttctttt gctttgttac cacttgtcac tgtctccatg ttaaaatgcc aaaaatgatg
3241 tagttgttgt tgcttttttc cctattttcc accccagtcg ctccttaccg tgactcctgc
3301 ccttggaggg catgtagcag tgtctgtcct gccagtccca aggccctgtg ggaggagact
3361 ggcctgcatc tctctaagac ttagtctgac gccacgcgca tctcttgttc tgtgttcaat
3421 cagtagtcca ggggagaagc ttctgctact tcagagcttt gctaaactaa cctaatttgt
3481 ccaaatcacc ccaaaaccac catctctgac gtaagcttcc atgcgacagc ctgatccgtt
3541 tccctggaca ggtctctttc ctggaatgca gcccaggcac ctgtgctcct ggcacccttg
3601 aggtctctcc tttgagccgt ggtcaccgag agggttgagg acgcagcacc cgaggtccca
3661 gcctttgcag gagcctccct gggcttagct ggacttagat cttcggtggc ctcatgtaaa
3721 cgtggcagcc agcctcttct agaaccctag cccagggact ggagcaggaa agggaccttc
3781 aaagtgaaga ctgccttgtc ccgcagctcc ttctggctta gattgaaaca tgggcttcct
3841 aatgggttaa atcctttaaa acaaggagtt gtgggggaag ggtgtcgtgc actcctagag
3901 aaaggtacac agttgcccgg ttgggaatgt gcttggcgct gaccctgcgg gcatctgact
3961 ggtcttccag ctcaggaaaa agaatttgaa agaggcttag cgtgaagggg aatcaaagag
4021 gaggttgtga tttggtcgaa ggtgcctggt ttagtgctgt aattgtctta ttattttttt
4081 tatatatata tttcttggag taaacatttt aaat
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