LOCUS AJ419866 1954 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for extra-cellular ribonuclease (RNASE6PL gene),
splice variant-1.
ACCESSION AJ419866
VERSION AJ419866.1
KEYWORDS alternative splicing; extra-cellular ribonuclease; RNASE6PL gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1954)
AUTHORS Ganesan T.S.
JOURNAL Submitted (09-NOV-2001) to the INSDC. Ganesan T.S., Institute of
Molecular Medicine, ICRF Molecular Oncology Laboratories, John
Radcliffe Hospital, Oxford, UNITED KINGDOM.
REFERENCE 3
AUTHORS Liu Y., Emilion G., Mungall A.J., Dunham I., Beck S.,
LeMeuth-Metzinger V., Shelling A.N., Charnock F.M., Ganesan T.S.
TITLE Physical and transcript map of the region between D6S264 and D6S149
on chromosome 6q27, the minimal region of allele loss in sporadic
epithelial ovarian cancer
JOURNAL Oncogene 21(3), 387-399(2002).
PUBMED 11821951
COMMENT Related sequences: U85625, AJ419866, AJ419867.
FEATURES Location/Qualifiers
source 1..1954
/db_xref="H-InvDB:HIT000247696"
/organism="Homo sapiens"
/chromosome="6q27"
/mol_type="mRNA"
/clone_lib="Soares fetal liver spleen 1NFLS"
/clone="199297"
/db_xref="taxon:9606"
CDS 362..727
/gene="RNASE6PL"
/product="extra-cellular ribonuclease"
/note="alternative"
/note="splice variant-1, coding sequence in first five
exons"
/db_xref="GOA:O00584"
/db_xref="H-InvDB:HIT000247696.13"
/db_xref="HGNC:HGNC:21686"
/db_xref="InterPro:IPR001568"
/db_xref="InterPro:IPR018188"
/db_xref="InterPro:IPR033130"
/db_xref="InterPro:IPR033697"
/db_xref="InterPro:IPR036430"
/db_xref="PDB:3T0O"
/db_xref="UniProtKB/Swiss-Prot:O00584"
/protein_id="CAD12031.1"
/translation="MRPAALRGALLGCLCLALLCLGGADKRLRDNHEWKKLIMVQHWP
ETVCEKIQNDCRDPPDYWTIHGLWPDKSEGCNRSWPFNLEEIKKNWMEITDSSLPSPS
TLPIINIFYSVLHLLQLMN"
BASE COUNT 496 a 480 c 490 g 488 t
ORIGIN
1 gcgactgacc gtggtcgtgg gcggacggcg gctgcagcgc ggaggagctg gggtcgctgt
61 gggtcgcgaa gcagagcccg ggacgtgcgc gcttggtgca cgatcctgaa ggggagctcc
121 gaggggcccg ggtctccagg gctgctgcgg ccattcccgg agcccggcgc ggggcccgcg
181 agatactggt ttaggccgtc ccagggctcc gggcgcaccc ggtggccgct gctgcagcgg
241 agggagcgcg gcggcgcggg ggctcggaga cagcgtttct cccggaagtc ttcctcgggc
301 agcaggtggg aagtgggagc cggagcggca gctggcagcg ttctctccgc aggtcggcac
361 catgcgccct gcagccctgc gcggggccct gctgggctgc ctctgcctgg cgttgctttg
421 cctgggcggt gcggacaagc gcctgcgtga caaccatgag tggaaaaaac taattatggt
481 tcagcactgg cctgagacag tatgcgagaa aattcaaaac gactgtagag accctccgga
541 ttactggaca atacatggac tatggcccga taaaagtgaa ggatgtaata gatcgtggcc
601 cttcaattta gaagagatta agaaaaattg gatggagatt acagacagtt cactcccttc
661 cccctcaact ctcccaatca ttaacatctt ctatagtgtg ttacatttgt tacaattaat
721 gaactgatac tgatacttta ttattaaata aagtttagca ttaacattag ggtttactcc
781 tgtgttgtgc ggctttggac aaatgcagga gagcaagtcc cacccagtgt gctctggagc
841 agccgctggc cctaaacccc ctgagccata cctccccttc ttcctcccct tgaaccccca
901 agcaaccgcg aatctcattc ctgtctctta agactacctt ttccaaattg tcacgtcgtt
961 ggaatcatac agtatgtagc ctctgcagac tggcttcttg cacttagcaa tgtatgtttg
1021 cagttcctcc agtgtctttt catgactcga cggctcattg gtttttgttg ctgaaaatat
1081 tccattgttt ggatgtacac tttatccctt cacctataac agcttgtatt ttcgtgtgca
1141 gttttatgat tactcaaatt gcacttgtag atatatctta acaaacactt catacaaaat
1201 aagcatagta ttattttatt caccaaagta ttgttaatta gcagagctca attctttggt
1261 gtcagtttat caaatttacc ttctaggttt tgagtttatt attaagaacc tgcgtagact
1321 tattttattt tttaatgcat aggatctttt gccagaaatg agggcatact ggcctgacgt
1381 aattcactcg tttcccaatc gcagccgctt ctggaagcat gagtgggaaa agcatgggac
1441 ctgcgccgcc caggtggatg cgctcaactc ccagaagaag tactttggca gaagcctgga
1501 actctacagg gagctggacc tcaacagtgt gcttctaaaa ttggggataa aaccatccat
1561 caattactac caagttgcag attttaaaga tgcccttgcc agagtatatg gagtgatacc
1621 caaaatccag tgccttccac caagccagga tgaggaagta cagacaattg gtcagataga
1681 actgtgcctc actaagcaag accagcagct gcaaaactgc accgagccgg gggagcagcc
1741 gtcccccaag caggaagtct ggctggcaaa tggggccgcc gagatccggg gtctgagagt
1801 ctgtgaagat ggcccagtct tctatccccc acctaaaaag accaagcatt gatgcccaag
1861 ttttggaaat attctgtttt aaaaatcaag agaaattcac aaactgcagc tttctaaaaa
1921 acaaaaaaaa aaaaaaaaaa agatctttaa ttaa
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