LOCUS AJ419231 3870 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for polyhomeotic 2 (PHC2 gene).
ACCESSION AJ419231
VERSION AJ419231.1
KEYWORDS early development regulator 2; EDR2; PHC2 gene; polyhomeotic 2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3870)
AUTHORS Strachan T.
JOURNAL Submitted (01-NOV-2001) to the INSDC. Strachan T., Institute of
Human Genetics, University of Newcastle-upon-Tyne, International
Centre for Life, Central Parkway, Newcastle-upon-Tyne, NE1 3BZ,
UNITED KINGDOM.
REFERENCE 3
AUTHORS Tonkin E., Hagan D.M., Li W., Strachan T.
TITLE Identification and characterisation of novel mammalian homologues
of Drosophila polyhomeoticpermits new insights into relationships
between members of the polyhomeotic family
JOURNAL Hum. Genet. 111(4-5), 435-442(2002).
PUBMED 12384788
FEATURES Location/Qualifiers
source 1..3870
/db_xref="H-InvDB:HIT000247694"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..3870
/gene="PHC2"
5'UTR <1..54
/gene="PHC2"
exon <1..228
/gene="PHC2"
/number=1
CDS 55..2631
/gene="PHC2"
/product="polyhomeotic 2"
/note="early development regulator 2, Edr2"
/db_xref="GOA:Q8IXK0"
/db_xref="H-InvDB:HIT000247694.14"
/db_xref="HGNC:HGNC:3183"
/db_xref="InterPro:IPR001660"
/db_xref="InterPro:IPR012313"
/db_xref="InterPro:IPR013761"
/db_xref="InterPro:IPR038603"
/db_xref="UniProtKB/Swiss-Prot:Q8IXK0"
/protein_id="CAD11673.1"
/translation="MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQ
ISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQ
LQSLAAVQQASLVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAA
ASGIAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPT
PAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASP
AGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQ
LLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSE
AHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQH
TSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPT
SPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKP
QILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEME
EPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHS
DRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRC
SDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVED
VYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLK
DS"
exon 229..387
/gene="PHC2"
/number=2
exon 388..465
/gene="PHC2"
/number=3
exon 466..630
/gene="PHC2"
/number=4
exon 631..717
/gene="PHC2"
/number=5
exon 718..1030
/gene="PHC2"
/number=6
exon 1031..1443
/gene="PHC2"
/number=7
exon 1444..1609
/gene="PHC2"
/number=8
exon 1610..1812
/gene="PHC2"
/number=9
exon 1813..1942
/gene="PHC2"
/number=10
exon 1943..2057
/gene="PHC2"
/number=11
exon 2058..2199
/gene="PHC2"
/number=12
exon 2200..2476
/gene="PHC2"
/number=13
exon 2477..3870
/gene="PHC2"
/number=14
3'UTR 2632..3870
/gene="PHC2"
BASE COUNT 846 a 1280 c 1031 g 713 t
ORIGIN
1 catctgcctg cccttctgcc atccgagcgc cctgactgcg ccacactgca ggccatggag
61 aatgagctgc cagtcccaca tacatctagc agtgcctgtg ccaccagcag taccagcggg
121 gccagtagca gcagtggctg caacaacagc agcagtggtg gaagtggccg ccccaccggg
181 ccccagattt ctgtgtacag tggtattcca gaccggcaga ccgtgcaggt gatccagcag
241 gccctgcaca gacagcccag cacggccgct cagtacctgc agcagatgta cgccgcccag
301 cagcagcacc tcatgctgca gaccgcggcg ctccagcagc agcacctcag cagcgcccag
361 ctccagagcc tggcagccgt acagcaggca agcctggtat ccaatagaca aggaagcact
421 tcaggcagca atgtgtctgc gcaggccccg gcccagtcat cttcgatcaa cctggcagcc
481 tccccagcag cagcccagct cctcaaccgg gcccagagtg tgaactctgc agcagcctca
541 ggcatcgctc agcaggctgt gctcttgggc aacacgtctt ccccagccct gactgcaagc
601 caagcacaga tgtatctgag ggcacagatg ctcatcttca cgcccacggc caccgtcgct
661 actgtgcagc ctgagctcgg cactggctcc cccgcccggc cccccacccc cgcccaggta
721 cagaacttga ccctccgaac acagcagaca ccagcggcag cagcctcggg ccccaccccc
781 actcagcctg tcctgcccag cttggccctg aaacccacgc cgggcggtag ccagcctctg
841 cctaccccag cacagagcag aaatactgct caggcttccc ctgcaggtgc caagcctggc
901 atagctgaca gtgtgatgga gccacacaag aaaggagatg gcaacagcag tgtgccaggg
961 agcatggaag gccgggctgg gctcagccgg acggttcctg ctgtggctgc ccaccccctc
1021 attgcaccag cctatgctca gctgcagcca caccagctcc tcccacagcc atcctcaaag
1081 cacctgcagc cccaatttgt gatccagcag cagccacagc cacaacagca gcagccgccg
1141 ccccagcagt cacggcctgt gctccaagct gagccccacc cccagctcgc ctcagtctct
1201 ccaagcgtgg ccctccagcc cagctcagag gcccatgcca tgccactagg cccggttaca
1261 cccgccctgc cactccagtg tcccactgcc aacctgcaca agcctggcgg cagtcagcag
1321 tgtcaccctc ccacacctga tactgggcct cagaatggac atcccgaggg cgtgccccac
1381 acccctcaac gcaggttcca gcacacttca gctgtcatct tacaactgca gcctgcttca
1441 ccaccccagc agtgtgtccc tgatgactgg aaagaagtgg caccagggga gaaaagtgtg
1501 cctgagacgc ggtctggccc atcaccacat cagcaggcta ttgtcactgc catgcctggt
1561 ggcctgcctg tacccacgag ccctaacatc cagccgtccc cagctcacga gacagggcag
1621 ggcattgttc atgcactgac cgacctcagc agccccggca tgacctcagg gaacggaaac
1681 tctgcctcca gcatcgccgg cactgccccc cagaatggtg agaataaacc accacaggcc
1741 attgtgaaac cccaaatcct gacgcatgtt atcgaagggt ttgtgatcca ggagggggcg
1801 gagcctttcc cggtgggacg ctcgtccctg ctggtgggga atctcaagaa gaagtatgca
1861 caggggttcc tgcctgagaa acttccacag caggatcaca ccaccaccac tgactcggag
1921 atggaggagc cctatctgca agaatccaaa gaggagggtg ctcccctcaa actcaagtgt
1981 gagctctgtg gccgggtgga ctttgcctat aagttcaagc gttccaagcg cttctgttcc
2041 atggcttgtg caaagaggta caacgtggga tgcaccaaac gggtgggact tttccactca
2101 gaccggagca agctgcagaa ggcaggagct gcgacccaca accgccgtcg ggccagcaaa
2161 gccagtctgc caccacttac caaggatacc aagaagcagc caacaggcac tgtgcccctt
2221 tcggttactg ctgctttgca gctaacacac agccaggaag actccagccg ttgctcagat
2281 aactcaagct atgaggaacc cttgtcaccc atctcagcca gctcatctac ttcccgccgg
2341 cgacaaggcc agcgggacct ggagctcccc gacatgcata tgcgggacct ggtgggcatg
2401 ggacaccact tcctgccaag tgagcccacc aagtggaatg tagaagacgt ctacgaattc
2461 atccgctctc tgccaggctg ccaggagata gcagaggaat tccgtgccca ggaaatcgac
2521 gggcaagccc tgctgctgct caaggaggac cacctgatga gcgccatgaa catcaagctg
2581 gggcccgccc tgaagatcta cgcccgcatc agcatgctca aggactccta gggctggtgg
2641 cagccaggat tctggcccag ggcgcctcct cccgactgag cagagccaga cagacattcc
2701 tgaggggccc agaaatgggg ccggttggag ggcaggggct ctccctaggg gcatagctgg
2761 tgaggaggtc tgggcacctc ctccatggct ctcaggggcc tttcatttct gtgggagggg
2821 cagagaggta ggtggcacag aagatggggc tttatgcttg taaatattga tagcactggc
2881 ttcctccaaa gtcccaatac tctagccccg ctctcttccc ctctttctgt cccccatttt
2941 ccagggggta tatggtcagg gctccccaac ctgagttggg ttacttcaag ggcagccagc
3001 aggcctggat ggaggcctag aaagcccttg ccttccttcc tcccacttct ttctccaggc
3061 ctggttaact cttccgttgt cagcttctcc cccttcagcc tgtttctgca gcagccaggg
3121 ttctcccccc tacaccctct gcaggtggag agagagaagc tgggcccagc cgggccgtgc
3181 ctgctggcac agacgcctta acgctgtgtg tatgactgtg tgactgtgtg ggagcctgga
3241 ctgacagata ggccaagggc tactctctgg catctccagg tgttttgtag caaacagcca
3301 cttagtgctt tgtcctggac tccactcagc ctcaggatgg ggaatagcca agaatggcag
3361 cctcagcgca gaggcaaggt cagaaagaga cggcgcttca gagtttcctt tccagacacc
3421 cctccccgca ctgtgaagtt cccctgaccg ccctcctggt tcacaaagag cattaagaaa
3481 gctgcggtgg tctgagcaac atagcccaaa gggctgagcc tcctggcctg cctgcccgcc
3541 caccctggga gtcccagtgg tgaggctcag agaactgcta aggggaaaga acagctggag
3601 tttctgttga tgtgaagaag gcagctcttg gcctcccact cccacacttc tttgcctata
3661 aatcttccta gcagcaattt gagctacctg aggaggaggc agggcagaaa gggcgagggc
3721 ctgcctctga cctgccgtgt cctttgcagg aaggaggtag gcacctttct gagcttattc
3781 tattccccac ccacaccccc aggcagggtt ggaaatgaag gactttttta acctttgttt
3841 tgttttttaa aaataaatct gtaaaatctg
//