LOCUS AJ413269 834 bp mRNA linear HUM 07-OCT-2008 DEFINITION Homo sapiens mRNA for caspase-3 (CASP3 gene), N-terminal mutant form. ACCESSION AJ413269 VERSION AJ413269.1 KEYWORDS apoptosis-related cysteine protease; CASP3 gene; caspase-3. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 834) AUTHORS Vallette F.M. JOURNAL Submitted (26-SEP-2001) to the INSDC. Vallette F.M., IFR 26, UMR INSERM 419, 9, quai Moncousu, Nantes, 44035 Cedex 01, FRANCE. REFERENCE 2 AUTHORS Oliver L.J. TITLE Control of the activation of the procaspase-3 by a sequence located at the N-terminus of the p17 subunit JOURNAL Unpublished. FEATURES Location/Qualifiers source 1..834 /db_xref="H-InvDB:HIT000247616" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" CDS 1..834 /gene="CASP3" /product="caspase-3" /function="apoptosis-related cysteine protease" /note="N-terminal mutant form" /db_xref="GOA:P42574" /db_xref="H-InvDB:HIT000247616.12" /db_xref="HGNC:HGNC:1504" /db_xref="InterPro:IPR001309" /db_xref="InterPro:IPR002138" /db_xref="InterPro:IPR002398" /db_xref="InterPro:IPR015917" /db_xref="InterPro:IPR016129" /db_xref="InterPro:IPR029030" /db_xref="InterPro:IPR033139" /db_xref="PDB:1CP3" /db_xref="PDB:1GFW" /db_xref="PDB:1I3O" /db_xref="PDB:1NME" /db_xref="PDB:1NMQ" /db_xref="PDB:1NMS" /db_xref="PDB:1PAU" /db_xref="PDB:1QX3" /db_xref="PDB:1RE1" /db_xref="PDB:1RHJ" /db_xref="PDB:1RHK" /db_xref="PDB:1RHM" /db_xref="PDB:1RHQ" /db_xref="PDB:1RHR" /db_xref="PDB:1RHU" /db_xref="PDB:2C1E" /db_xref="PDB:2C2K" /db_xref="PDB:2C2M" /db_xref="PDB:2C2O" /db_xref="PDB:2CDR" /db_xref="PDB:2CJX" /db_xref="PDB:2CJY" /db_xref="PDB:2CNK" /db_xref="PDB:2CNL" /db_xref="PDB:2CNN" /db_xref="PDB:2CNO" /db_xref="PDB:2DKO" /db_xref="PDB:2H5I" /db_xref="PDB:2H5J" /db_xref="PDB:2H65" /db_xref="PDB:2J30" /db_xref="PDB:2J31" /db_xref="PDB:2J32" /db_xref="PDB:2J33" /db_xref="PDB:2XYG" /db_xref="PDB:2XYH" /db_xref="PDB:2XYP" /db_xref="PDB:2XZD" /db_xref="PDB:2XZT" /db_xref="PDB:2Y0B" /db_xref="PDB:3DEH" /db_xref="PDB:3DEI" /db_xref="PDB:3DEJ" /db_xref="PDB:3DEK" /db_xref="PDB:3EDQ" /db_xref="PDB:3GJQ" /db_xref="PDB:3GJR" /db_xref="PDB:3GJS" /db_xref="PDB:3GJT" /db_xref="PDB:3H0E" /db_xref="PDB:3ITN" /db_xref="PDB:3KJF" /db_xref="PDB:3PCX" /db_xref="PDB:3PD0" /db_xref="PDB:3PD1" /db_xref="PDB:4DCJ" /db_xref="PDB:4DCO" /db_xref="PDB:4DCP" /db_xref="PDB:4EHA" /db_xref="PDB:4EHD" /db_xref="PDB:4EHF" /db_xref="PDB:4EHH" /db_xref="PDB:4EHK" /db_xref="PDB:4EHL" /db_xref="PDB:4EHN" /db_xref="PDB:4JJE" /db_xref="PDB:4JQY" /db_xref="PDB:4JQZ" /db_xref="PDB:4JR0" /db_xref="PDB:4PRY" /db_xref="PDB:4PS0" /db_xref="PDB:4QTX" /db_xref="PDB:4QTY" /db_xref="PDB:4QU0" /db_xref="PDB:4QU5" /db_xref="PDB:4QU8" /db_xref="PDB:4QU9" /db_xref="PDB:4QUA" /db_xref="PDB:4QUB" /db_xref="PDB:4QUD" /db_xref="PDB:4QUE" /db_xref="PDB:4QUG" /db_xref="PDB:4QUH" /db_xref="PDB:4QUI" /db_xref="PDB:4QUJ" /db_xref="PDB:4QUL" /db_xref="PDB:5I9B" /db_xref="PDB:5I9T" /db_xref="PDB:5IAB" /db_xref="PDB:5IAE" /db_xref="PDB:5IAG" /db_xref="PDB:5IAJ" /db_xref="PDB:5IAK" /db_xref="PDB:5IAN" /db_xref="PDB:5IAR" /db_xref="PDB:5IAS" /db_xref="PDB:5IBC" /db_xref="PDB:5IBP" /db_xref="PDB:5IBR" /db_xref="PDB:5IC4" /db_xref="UniProtKB/Swiss-Prot:P42574" /protein_id="CAC88866.1" /translation="MENTENSVDSKSIKNLEPKIIHGSESMDSGMSWDTGYKMDYPEM GLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRD VSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFII QACRGTELDCGIETDSGVDDDMACHKIPVDADFLYAYSTAPGYYSWRNSKDGSWFIQS LCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY H" BASE COUNT 271 a 147 c 181 g 235 t ORIGIN 1 atggagaaca ctgaaaactc agtggattca aaatccatta aaaatttgga accaaagatc 61 atacatggaa gcgaatcaat ggactctgga atgtcctggg acaccggtta taaaatggat 121 tatcctgaga tgggtttatg tataataatt aataataaga attttcataa aagcactgga 181 atgacatctc ggtctggtac agatgtcgat gcagcaaacc tcagggaaac attcagaaac 241 ttgaaatatg aagtcaggaa taaaaatgat cttacacgtg aagaaattgt ggaattgatg 301 cgtgatgttt ctaaagaaga tcacagcaaa aggagcagtt ttgtttgtgt gcttctgagc 361 catggtgaag aaggaataat ttttggaaca aatggacctg ttgacctgaa aaaaataaca 421 aactttttca gaggggatcg ttgtagaagt ctaactggaa aacccaaact tttcattatt 481 caggcctgcc gtggtacaga actggactgt ggcattgaga cagacagtgg tgttgatgat 541 gacatggcgt gtcataaaat accagtggat gccgacttct tgtatgcata ctccacagca 601 cctggttatt attcttggcg aaattcaaag gatggctcct ggttcatcca gtcgctttgt 661 gccatgctga aacagtatgc cgacaagctt gaatttatgc acattcttac ccgggttaac 721 cgaaaggtgg caacagaatt tgagtccttt tcctttgacg ctacttttca tgcaaagaaa 781 cagattccat gtattgtttc catgctcaca aaagaactct atttttatca ctaa //