LOCUS AJ404611 5941 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for B-cell lymphoma/leukaemia 11A extra long form
(BCL11A-XL gene).
ACCESSION AJ404611
VERSION AJ404611.1
KEYWORDS B-cell lymphoma/leukaemia 11A; BCL11A-XL gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5941)
AUTHORS Willis T.G.
JOURNAL Submitted (19-JUN-2000) to the INSDC. Willis T.G., Academic
Haematology And Cytogenetics, Institute Of Cancer Research, Sutton,
SURREY SM2 5NG, UNITED KINGDOM.
REFERENCE 2
AUTHORS Satterwhite E., Sonoki T., Willis T.G., Harder L., Nowak R.,
Arriola E.L., Liu H., Price H.P., Gesk S., Steinemann D.,
Schlegelberger B., Oscier D.G., Siebert R., Tucker P.W.,
Dyer M.J.S.
TITLE The BCL11 gene family: involvement of BCL11A in lymphoid
malignancies
JOURNAL Blood 98(12), 3413-3420(2001).
PUBMED 11719382
FEATURES Location/Qualifiers
source 1..5941
/db_xref="H-InvDB:HIT000247487"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 229..2736
/gene="BCL11A-XL"
/product="B-cell lymphoma/leukaemia 11A extra long form"
/db_xref="GOA:Q9H165"
/db_xref="H-InvDB:HIT000247487.14"
/db_xref="HGNC:HGNC:13221"
/db_xref="InterPro:IPR013087"
/db_xref="InterPro:IPR036236"
/db_xref="PDB:5VTB"
/db_xref="UniProtKB/Swiss-Prot:Q9H165"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAC17723.1"
/translation="MSRRKQGKPQHLSKREFSPEPLEAILTDDEPDHGPLGAPEGDHD
LLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKAVDKPPSPSPIEMKKASNPVEVG
IQVTPEDDDCLSTSSRRICPKQEHIADKLLHWRGLSSPRSAHGALIPTPGMSAEYAPQ
GICKDEPSSYTCTTCKQPFTSAWFLLQHAQNTHGLRIYLESEHGSPLTPRVGIPSGLG
AECPSQPPLHGIHIADNNPFNLLRIPGSVSREASGLAEGRFPPTPPLFSPPPRHHLDP
HRIERLGAEEMALATHHPSAFDRVLRLNPMAMEPPAMDFSRRLRELAGNTSSPPLSPG
RPSPMQRLLQPFQPGSKPPFLATPPLPPLQSAPPPSQPPVKSKSCEFCGKTFKFQSNL
VVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTHMHKSSPMTVKSDDGLSTASSPEP
GTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEEEEEEEEEEELTES
ERVDYGFGLSLEAARHHENSSRGAVVGVGDESRALPDVMQGMVLSSMQHFSEAFHQVL
GEKHKRGHLAEAEGHRDTCDEDSVAGESDRIDDGTVNGRGCSPGESASGGLSKKLLLG
SPSSLSPFSKRIKLEKEFDLPPATMPNTENVYSQWLAGYAASRQLKDPFLSFGDSRQS
PFASSSEHSSENGSLRFSTPPGELDGGISGRSGTGSGGSTPHISGPGTGRPSSKEGRR
SDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKD
VYKCEICKMPFSVYSTLEKHMKKWHSDRVLNNDIKTE"
regulatory 5926..5931
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1684 a 1334 c 1282 g 1641 t
ORIGIN
1 tttttttttt ttttttgctt aaaaaaaagc catgacggct ctcccacaat tcatcttccc
61 tgcgccatct ttgtattatt tctaatttat tttggatgtc aaaaggcact gatgaagata
121 ttttctctgg agtctccttc tttctaaccc ggctctcccg atgtgaaccg agccgtcgtc
181 cgcccgccgc cgccgccgcc gccgccgccg cccgccccgc agcccaccat gtctcgccgc
241 aagcaaggca aaccccagca cttaagcaaa cgggaattct cgcccgagcc tcttgaagcc
301 attcttacag atgatgaacc agaccacggc ccgttgggag ctccagaagg ggatcatgac
361 ctcctcacct gtgggcagtg ccagatgaac ttcccattgg gggacattct tatttttatc
421 gagcacaaac ggaaacaatg caatggcagc ctctgcttag aaaaagctgt ggataagcca
481 ccttcccctt caccaatcga gatgaaaaaa gcatccaatc ccgtggaggt tggcatccag
541 gtcacgccag aagatgacga ttgtttatca acgtcatcta gaagaatttg ccccaaacag
601 gaacacatag cagataaact tctgcactgg aggggcctct cctcccctcg ttctgcacat
661 ggagctctaa tccccacgcc tgggatgagt gcagaatatg ccccgcaggg tatttgtaaa
721 gatgagccca gcagctacac atgtacaact tgcaaacagc cattcaccag tgcatggttt
781 ctcttgcaac acgcacagaa cactcatgga ttaagaatct acttagaaag cgaacacgga
841 agtcccctga ccccgcgggt tggtatccct tcaggactag gtgcagaatg tccttcccag
901 ccacctctcc atgggattca tattgcagac aataacccct ttaacctgct aagaatacca
961 ggatcagtat cgagagaggc ttccggcctg gcagaagggc gctttccacc cactcccccc
1021 ctgtttagtc caccaccgag acatcacttg gacccccacc gcatagagcg cctgggggcg
1081 gaagaaatgg ccctggccac ccatcacccg agtgcctttg acagggtgct gcggttgaat
1141 ccaatggcta tggagcctcc cgccatggat ttctctagga gacttagaga gctggcaggg
1201 aacacgtcta gcccaccgct gtccccaggc cggcccagcc ctatgcaaag gttactgcaa
1261 ccattccagc caggtagcaa gccgcccttc ctggcgacgc cccccctccc tcctctgcaa
1321 tccgcccctc ctccctccca gcccccggtc aagtccaagt catgcgagtt ctgcggcaag
1381 acgttcaaat ttcagagcaa cctggtggtg caccggcgca gccacacggg cgagaagccc
1441 tacaagtgca acctgtgcga ccacgcgtgc acccaggcca gcaagctgaa gcgccacatg
1501 aagacgcaca tgcacaaatc gtcccccatg acggtcaagt ccgacgacgg tctctccacc
1561 gccagctccc cggaacccgg caccagcgac ttggtgggca gcgccagcag cgcgctcaag
1621 tccgtggtgg ccaagttcaa gagcgagaac gaccccaacc tgatcccgga gaacggggac
1681 gaggaggaag aggaggacga cgaggaagag gaagaagagg aggaagagga ggaggaggag
1741 ctgacggaga gcgagagggt ggactacggc ttcgggctga gcctggaggc ggcgcgccac
1801 cacgagaaca gctcgcgggg cgcggtcgtg ggcgtgggcg acgagagccg cgccctgccc
1861 gacgtcatgc agggcatggt gctcagctcc atgcagcact tcagcgaggc cttccaccag
1921 gtcctgggcg agaagcataa gcgcggccac ctggccgagg ccgagggcca cagggacact
1981 tgcgacgaag actcggtggc cggcgagtcg gaccgcatag acgatggcac tgttaatggc
2041 cgcggctgct ccccgggcga gtcggcctcg gggggcctgt ccaaaaagct gctgctgggc
2101 agccccagct cgctgagccc cttctctaag cgcatcaagc tcgagaagga gttcgacctg
2161 cccccggcca cgatgcccaa cacggagaac gtgtactcgc agtggctcgc cggctacgcg
2221 gcctccaggc agctcaaaga tcccttcctt agcttcggag actccagaca atcgcctttt
2281 gcctcctcgt cggagcactc ctcggagaac gggagcttgc gcttctccac accgcccggg
2341 gagctggacg gagggatctc ggggcgcagc ggcacgggaa gtggagggag cacgccccat
2401 attagtggtc cgggcacggg caggcccagc tcaaaagagg gcagacgcag cgacacttgt
2461 gagtactgtg ggaaagtctt caagaactgt agcaatctca ctgtccacag gagaagccac
2521 acgggcgaaa ggccttataa atgcgagctg tgcaactatg cctgtgccca gagtagcaag
2581 ctcaccaggc acatgaaaac gcatggccag gtggggaagg acgtttacaa atgtgaaatt
2641 tgtaagatgc cttttagcgt gtacagtacc ctggagaaac acatgaaaaa atggcacagt
2701 gatcgagtgt tgaataatga tataaaaact gaatagaggt atattaatac ccctccctca
2761 ctcccacctg acaccccctt tttcaccact ccctttcccc atcgccctcc agccccactc
2821 cctgtaggat ttttttctag tcccatgtga tttaaacaaa caaacaaaca aacagaagta
2881 acgaagctaa gaatatgaga gtgcttgtca ccagcacacc tgtttttttt ctttttcttt
2941 ttcttttttc tttttccttt tttttttttt tcctttatgt tctcaccgtt tgaatgcatg
3001 atctgtatgg ggcaatacta ttgcatttta cgcaaacttt gagcctttct cttgtgcaat
3061 aatttacatg ttgtgtatgt ttttttttaa acttagacag catgtatggt atgttatggc
3121 tattttaaat tgtccctaat tcgttgctga gcaaacatgt tgctgtttcc agttccgttc
3181 tgagagaaaa agagagagag agagaaaaag accatgctgc atacattctg taatacatat
3241 catgtacagt tttattttat aacgtgagga ggaaaaacag tctttggatt aaccctctat
3301 agacagaata gatagcactg aaaaaaaatc tctatgagct aaatgtctgt ctctaaaggg
3361 ttaaatgtat caattggaaa ggaagaaaaa aggccttgaa ttgacaaatt aacagaaaaa
3421 cagaacaagt ttattctatc atttggtttt aaaatatgag tgccttggat ctattaaaac
3481 cacatcgatg gttctttcta cttgttataa acttgtagct taattcagca ttgggtgagg
3541 taataaacct taggaactag catataattc tatattgtat ttctcacaac aatggctacc
3601 taaaaagatg acccattatg tcctagttaa tcatcatttt tcctttagtt taattttata
3661 aacaaaactg attataccag tataaaagct actttgctcc tggtgagagc ttaaaagaaa
3721 tgggctgttt tgcccaaagt tttatttttt ttaaacaatg attaaattga atgtgtaatg
3781 tgcaaaagcc ctggaacgca attaaataca ctagtaagga gttcatttta tgaagatatt
3841 tgctttaata atgtcttttt aaaaatactg gcaccaaaag aaatagatcc agatctactt
3901 ggttgtcaag tggacaatca aatgataaac tttaagacct tgtataccat attgaaagga
3961 agaggctgac aataaggttt gacagagggg aacagaagaa aataatatga tttattagca
4021 caacgtggta ctatttgcca tttaaaacta gaacaggtat ataagctaat attgatacaa
4081 tgatgattaa ctatgaattc ttaagacttg catttaaatg tgacattctt aaaaaaagaa
4141 gagaaagaat tttaagagta gcagtatata tgtctgtgct ccctaaaagt tgtacttcat
4201 ttcttttcca tacactgtgt gctatttgtg ttaacatgga agaggattca ttgtttttat
4261 ttttattttt ttaatttttt cttttttatt aagctagcat ctgccccagt tggtgttcaa
4321 atagcacttg actctgcctg tgatatctgt atcttttctc taatcagaga tacagaggtt
4381 gagtataaaa taaacctgct cagataggac aattaagtgc actgtacaat tttcccagtt
4441 tacaggtcta tacttaaggg aaaagttgca agaatgctga aaaaaaattg aacacaatct
4501 cattgaggag cattttttaa aaactaaaaa aaaaaaaact ttgccagcca tttacttgac
4561 tattgagctt acttacttgg acgcaacatt gcaagcgctg tgaatggaaa cagaatacac
4621 ttaacataga aatgaatgat tgctttcgct tctacagtgc aaggattttt ttgtacaaaa
4681 cttttttaaa tataaatgtt aagaaaaatt ttttttaaaa aacacttcat tatgtttagg
4741 ggggaactgc attttagggt tccattgtct tggtggtgtt acaagacttg ttatccattt
4801 aaaaatggta gtggaaattc tatgccttgg atacacaccg ctcttcaggt tgtaaaaaaa
4861 aaaaacatac attggggaaa ggtttaagat tatatagtac ttaaatatag gaaaatgcac
4921 actcatgttg attcctatgc taaaatacat ttatggtctt ttttctgtat ttctagaatg
4981 gtatttgaat taaatgttca tctagtgtta ggcactatag tatttatatt gaagcttgta
5041 tttttaactg ttgcttgttc tcttaaaagg tatcaatgta ccttttttgg tagtggaaaa
5101 aaaaaagaca ggctgccaca gtatattttt ttaatttggc aggataatat agtgcaaatt
5161 atttgtatgc ttcaaaaaaa aaaaaaagag agaaacaaaa aagtgtgaca ttacagatga
5221 gaagccatat aatggcggtt tgggggagcc tgctagaatg tcacatggat ggctgtcata
5281 ggggttgtac atatcctttt ttgttccttt ttcctgctgc catactgtat gcagtactgc
5341 aagctaataa cgttggtttg ttatgtagtg tgctttttgt ccctttcctt ctatcaccct
5401 acattccagc atcttacctt catatgcagt aaaagaaaga aagaaaaaaa aaggaaaaaa
5461 aaaaaaaaac caatgttttg cagttttttt cattgccaaa aactaaatgg tgctttatat
5521 ttagattgga aagaatttca tatgcaaagc atattaaaga gaaagcccgc tttagtcaat
5581 acttttttgt aaatggcaat gcagaatatt ttgttattgg ccttttctat tcctgtaatg
5641 aaagctgttt gtcgtaactt gaaattttat cttttactat gggagtcact atttattatt
5701 gcttatgtgc cctgttcaaa acagaggcac ttaatttgat cttttatttt tctttgtttt
5761 tatttttttt tttatttaga tgaccaaagg tcattacaac ctggcttttt attgtatttg
5821 tttctggtct ttgttaagtt ctattggaaa aaccactgtc tgtgtttttt tggcagttgt
5881 ctgcattaac ctgttcatac acccattttg tccctttatt gaaaaaataa aaaaaattaa
5941 a
//