LOCUS AJ404326 2042 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens SR+89 gene.
ACCESSION AJ404326
VERSION AJ404326.1
KEYWORDS SEA-alpha-thalassaemia; SR+89 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2042)
AUTHORS Utsch B.
JOURNAL Submitted (04-JUN-2000) to the INSDC. Utsch B., Department of
Clinical Biochemistry, University of Bonn, Sigmund-Freud-Strasse
25, Bonn 53105, Germany.
REFERENCE 2
AUTHORS Utsch B., Albers N., Wickert L., Bidlingmaier F., Ludwig M.
TITLE SR+89, a gene encoding a serine/arginine-rich protein, is widely
transcribed from human chromosome 16p13.3 proximal to the
alpha-globin cluster. Exclusion of this new gene as a candidate
gene for the hypospadic phenotype associated with homozygous
SEA-alpha-thalassaemia
JOURNAL Unpublished.
COMMENT Related sequence AK001093
FEATURES Location/Qualifiers
source 1..2042
/db_xref="H-InvDB:HIT000247482"
/organism="Homo sapiens"
/chromosome="16"
/map="16p13.3"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA join(<72..1082,1674..>1815)
/gene="SR+89"
/note="alternative splicing, type 2"
/experiment="experimental evidence, no additional details
recorded"
mRNA <72..>1049
/gene="SR+89"
/note="alternative splicing type 3 and 4"
/experiment="experimental evidence, no additional details
recorded"
CDS 72..1049
/gene="SR+89"
/note="alternative splicing type 3 and 4"
/db_xref="GOA:Q9NQ29"
/db_xref="H-InvDB:HIT000247482.12"
/db_xref="HGNC:HGNC:6723"
/db_xref="InterPro:IPR004882"
/db_xref="UniProtKB/Swiss-Prot:Q9NQ29"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB93981.1"
/translation="MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCC
PHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTE
LAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVE
KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF
IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR
RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYK"
CDS join(72..1045,1674..1815)
/codon_start=1
/product="SR+89"
/db_xref="GOA:Q9NQ29"
/db_xref="HGNC:HGNC:6723"
/db_xref="InterPro:IPR004882"
/db_xref="UniProtKB/Swiss-Prot:Q9NQ29"
/protein_id="CAB93982.1"
/translation="MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCC
PHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTE
LAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVE
KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF
IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR
RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASRE
ESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGEI"
misc_binding 636..716
/bound_moiety="nucleic acid binding molecule"
/inference="non-experimental evidence, no additional
details recorded"
misc_feature 894..947
/gene="SR+89"
/note="bipartite nuclear targeting sequence"
misc_feature 930..983
/gene="SR+89"
/note="bipartite nuclear targeting sequence"
regulatory 1468..1473
/experiment="experimental evidence, no additional details
recorded"
/regulatory_class="polyA_signal_sequence"
regulatory 1996..2001
/experiment="experimental evidence, no additional details
recorded"
/regulatory_class="polyA_signal_sequence"
regulatory 1999..2005
/experiment="experimental evidence, no additional details
recorded"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 471 a 479 c 624 g 468 t
ORIGIN
1 tgtcgacgcc gctgccaccg cctgcctgag agaagtcgtc gcggccgacc ccgtcgcctc
61 cgccggctac catgtccgcc caggcgcaga tgcgggccct gctggaccag ctcatgggca
121 cggctcggga cggagacgaa accagacaaa gggtcaagtt tacagatgac cgtgtctgca
181 agagtcacct tctggactgc tgcccccatg acatcctggc tgggacgcgc atggatttag
241 gagaatgtac caaaatccac gacttggccc tccgagcaga ttatgagatt gcaagtaaag
301 aaagagacct gttttttgaa ttagatgcaa tggatcactt ggagtccttt attgctgaat
361 gtgatcggag aactgagctc gccaagaagc ggctggcaga aacacaggag gaaatcagtg
421 cggaagtttc tgcaaaggca gaaaaagtac atgagttaaa tgaagaaata ggaaaactcc
481 ttgctaaagc cgaacagcta ggggctgaag gtaatgtgga tgaatcccag aagattctta
541 tggaagtgga aaaagttcgt gcgaagaaaa aagaagctga ggaagaatac agaaattcca
601 tgcctgcatc cagttttcag cagcaaaagc tgcgtgtctg cgaggtctgt tcagcctacc
661 ttggtctcca tgacaatgac cgtcgcctgg cagaccactt cggtggcaag ttacacttgg
721 ggttcattca gatccgagag aagcttgatc agttgaggaa aactgtcgct gaaaagcagg
781 agaagagaaa tcaggatcgc ttgaggagga gagaggagag ggaacgggag gagcgtctga
841 gcaggaggtc gggatcaaga accagagatc gcaggaggtc acgctcccgg gatcggcgtc
901 ggaggcggtc aagatctacc tcccgagagc gacggaaatt gtcccggtcc cggtcccgag
961 atagacatcg gcgccaccgc agccgttccc ggagccacag ccggggacat cgtcgggctt
1021 cccgggaccg aagtgcgaaa tacaagtaac tactctgact ccttcggtag ctgcaaccag
1081 gagtgagccc ttctctgtgt tcccagggtc tgctgagggc cgtgtctggt ggggatgggg
1141 ctgggctcac cctcaggagt agggctgggg agtcgtgaac gggactcagg tgtgggaaga
1201 ggcgagaggg ctgtggagga gctcgcacgg cgccaggtga tgggctgcac aggcactgtc
1261 ccctgcctgc gtcctggggc ctgtgcactg ttgcgtccat gctcagagtg gctgagactt
1321 gtgtcctgac caggccctgc ttacctctgt tttggttttt gtttttgata tttttttttc
1381 cattgtgttt ttacgtagtg tcatgttctg tgcatatagt gttgtattct cctttgcact
1441 gtttatgtta cagtgaaggc tctccttatt aaaaatcttc gcaaaggtca ctttttaatg
1501 gctatctaac actccatatg tggtgggcaa gtctggttgg cctccggggg gtttccaggt
1561 ataggggatg tagggccttg cctggcctgg tctgcgggtc catcgtcagt gcctgagcgg
1621 ccagcagaag gggggcagca gcctccactg agcctctggt tcccatttcc caggttctcc
1681 agagagcggg catccagaga ggagtcctgg gagagcgggc ggagcgagcg agggcccccg
1741 gactggaggc ttgagagctc caacgggaag atggcttcac ggaggtcaga agagaaggag
1801 gccggcgaga tctgaacccg tctcccgggt gctgtaaata gtctgataaa cgttcacaca
1861 gtctaaaatt accctttata tttgctgaat acaactcatc ttttgtagtt taaaatttct
1921 attgttttgg agctagctgt gagtttctag aagtgtacag agttgctcct gtgttcccgg
1981 gtcatgttga gtaggaataa ataaatctga tgctgcctcc tgaggctgcg gggggtttct
2041 gc
//