LOCUS AJ319876 2449 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for matriptase-2.
ACCESSION AJ319876
VERSION AJ319876.1
KEYWORDS matriptase-2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2449)
AUTHORS Lopez-Otin C.
JOURNAL Submitted (25-JUN-2001) to the INSDC. Lopez-Otin C., Bioquimica y
Biologia Molecular, Universidad de Oviedo, Edificio Santiago
Gascon, Campus del Cristo, Asturias, 33006, SPAIN.
REFERENCE 2
AUTHORS Velasco G., Cal S., Quesada V., Sanchez L.M., Lopez-Otin C.
TITLE Matriptase-2, a membrane-bound mosaic serine proteinase
predominantly expressed in human liver and showing degrading
activity against extracellular matrix proteins
JOURNAL J Biol Chem 277(40), 37637-37646(2002).
PUBMED 12149247
FEATURES Location/Qualifiers
source 1..2449
/db_xref="H-InvDB:HIT000247209"
/organism="Homo sapiens"
/chromosome="22"
/map="22q12"
/mol_type="mRNA"
/country="Spain"
/tissue_type="liver"
/db_xref="taxon:9606"
CDS 5..2413
/product="matriptase-2"
/function="serine protease"
/db_xref="GOA:Q8IU80"
/db_xref="H-InvDB:HIT000247209.13"
/db_xref="HGNC:HGNC:16517"
/db_xref="InterPro:IPR000082"
/db_xref="InterPro:IPR000859"
/db_xref="InterPro:IPR001254"
/db_xref="InterPro:IPR001314"
/db_xref="InterPro:IPR002172"
/db_xref="InterPro:IPR009003"
/db_xref="InterPro:IPR017118"
/db_xref="InterPro:IPR018114"
/db_xref="InterPro:IPR033116"
/db_xref="InterPro:IPR035914"
/db_xref="InterPro:IPR036055"
/db_xref="InterPro:IPR036364"
/db_xref="UniProtKB/Swiss-Prot:Q8IU80"
/protein_id="CAC85953.1"
/translation="MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRL
VPLFVLLALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAF
RSETVKAQKMLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPE
VVQALLVEELLSTVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYV
GQGQVLRLKGPDHLASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRL
ITSVYGCSRQEPVVEVLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDN
RLDSQGVLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQ
WTIQNRRLCGLRILQPYAERIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCP
GEFLCSVNGLCVPACDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCL
NGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSS
RIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVF
LGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPA
RSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAG
YRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQ
QVVT"
BASE COUNT 431 a 762 c 790 g 466 t
ORIGIN
1 caggatgccc gtggccgagg ccccccaggt ggctggcggg cagggggacg gaggtgatgg
61 cgaggaagcg gagccggagg ggatgttcaa ggcctgtgag gactccaaga gaaaagcccg
121 gggctacctc cgcctggtgc ccctgtttgt gctgctggcc ctgctcgtgc tggcttcggc
181 gggggtgcta ctctggtatt tcctagggta caaggcggag gtgatggtca gccaggtgta
241 ctcaggcagt ctgcgtgtac tcaatcgcca cttctcccag gatcttaccc gccgggaatc
301 tagtgccttc cgcagtgaaa ccgtcaaagc ccagaagatg ctcaaggagc tcatcaccag
361 cacccgcctg ggaacttact acaactccag ctccgtctat tcctttgggg agggacccct
421 cacttgcttc ttctggttca ttctccaaat ccccgagcac cgccggctga tgctgagccc
481 cgaggtggtg caggcactgc tggtggagga gctgctgtcc acagtcaaca gctcggctgc
541 cgtcccctac agggccgagt acgaagtgga ccccgagggc ctagtgatcc tggaagccag
601 tgtgaaagac atagctgcat tgaattccac gctgggttgt taccgctaca gctacgtggg
661 ccagggccag gtcctccggc tgaaggggcc tgaccacctg gcctccagct gcctgtggca
721 cctgcagggc cccaaggacc tcatgctcaa actccggctg gagtggacgc tggcagagtg
781 ccgggaccga ctggccatgt atgacgtggc cgggcccctg gagaagaggc tcatcacctc
841 ggtgtacggc tgcagccgcc aggagcccgt ggtggaggtt ctggcgtcgg gggccatcat
901 ggcggtcgtc tggaagaagg gcctgcacag ctactacgac cccttcgtgc tctccgtgca
961 gccggtggtc ttccaggcct gtgaagtgaa cctgacgctg gacaacaggc tcgactccca
1021 gggcgtcctc agcaccccgt acttccccag ctactactcg ccccaaaccc actgctcctg
1081 gcacctcacg gtgccctctc tggactacgg cttggccctc tggtttgatg cctatgcact
1141 gaggaggcag aagtatgatt tgccgtgcac ccagggccag tggacgatcc agaacaggag
1201 gctgtgtggc ttgcgcatcc tgcagcccta cgccgagagg atccccgtgg tggccacggc
1261 cgggatcacc atcaacttca cctcccagat ctccctcacc gggcccggtg tgcgggtgca
1321 ctatggcttg tacaaccagt cggacccctg ccctggagag ttcctctgtt ctgtgaatgg
1381 actctgtgtc cctgcctgtg atggggtcaa ggactgcccc aacggcctgg atgagagaaa
1441 ctgcgtttgc agagccacat tccagtgcaa agaggacagc acatgcatct cactgcccaa
1501 ggtctgtgat gggcagcctg attgtctcaa cggcagcgat gaagagcagt gccaggaagg
1561 ggtgccatgt gggacattca ccttccagtg tgaggaccgg agctgcgtga agaagcccaa
1621 cccgcagtgt gatgggcggc ccgactgcag ggacggctcg gatgaggagc actgtgactg
1681 tggcctccag ggcccctcca gccgcattgt tggtggagct gtgtcctccg agggtgagtg
1741 gccatggcag gccagcctcc aggttcgggg tcgacacatc tgtggggggg ccctcatcgc
1801 tgaccgctgg gtgataacag ctgcccactg cttccaggag gacagcatgg cctccacggt
1861 gctgtggacc gtgttcctgg gcaaggtgtg gcagaactcg cgctggcctg gagaggtgtc
1921 cttcaaggtg agccgcctgc tcctgcaccc gtaccacgaa gaggacagcc atgactacga
1981 cgtggcgctg ctgcagctcg accacccggt ggtgcgctcg gccgccgtgc gccccgtctg
2041 cctgcccgcg cgctcccact tcttcgagcc cggcctgcac tgctggatta cgggctgggg
2101 cgccttgcgc gagggcggcc ccatcagcaa cgctctgcag aaagtggatg tgcagttgat
2161 cccacaggac ctgtgcagcg aggtctatcg ctaccaggtg acgccacgca tgctgtgtgc
2221 cggctaccgc aagggcaaga aggatgcctg tcagggtgac tcaggtggtc cgctggtgtg
2281 caaggcactc agtggccgct ggttcctggc ggggctggtc agctggggcc tgggctgtgg
2341 ccggcctaac tacttcggcg tctacacccg catcacaggt gtgatcagct ggatccagca
2401 agtggtgacc tgaggaactg cccccctgca aacgcagggc ccacctcct
//