LOCUS AJ316284 6536 bp mRNA linear HUM 21-OCT-2008
DEFINITION Homo sapiens mRNA for neurexin 3-alpha (NRXN3 gene), cardiac
isoform.
ACCESSION AJ316284
VERSION AJ316284.2
KEYWORDS alternative splicing; neurexin 3-alpha; NRXN3 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Occhi G.
JOURNAL Submitted (10-SEP-2001) to the INSDC. Occhi G., Biology, Laboratory
of Human Genetics, Via U. Bassi 58/B, Padova, 35131, ITALY.
REMARK revised by [3]
REFERENCE 2
AUTHORS Occhi G., Rampazzo A., Beffagna G., Danieli G.A.
TITLE Identification and characterization of heart-specific splicing of
human neurexin 3 mRNA (NRXN3)
JOURNAL Biochem. Biophys. Res. Commun. 298(1), 151-155(2002).
PUBMED 12379233
REFERENCE 3 (bases 1 to 6536)
AUTHORS Occhi G.
JOURNAL Submitted (01-OCT-2002) to the INSDC. Occhi G., Biology, Laboratory
of Human Genetics, Via U. Bassi 58/B, Padova, 35131, ITALY.
FEATURES Location/Qualifiers
source 1..6536
/db_xref="H-InvDB:HIT000247183"
/organism="Homo sapiens"
/chromosome="14"
/mol_type="mRNA"
/tissue_type="heart"
/db_xref="taxon:9606"
CDS 794..4972
/gene="NRXN3"
/product="neurexin 3-alpha"
/note="cardiac isoform"
/db_xref="GOA:Q9Y4C0"
/db_xref="H-InvDB:HIT000247183.13"
/db_xref="HGNC:HGNC:8010"
/db_xref="InterPro:IPR000152"
/db_xref="InterPro:IPR000742"
/db_xref="InterPro:IPR001791"
/db_xref="InterPro:IPR003585"
/db_xref="InterPro:IPR013320"
/db_xref="InterPro:IPR027789"
/db_xref="UniProtKB/Swiss-Prot:Q9Y4C0"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAC87720.2"
/translation="MSSTLHSVFFTLKVSILLGSLLGLCLGLEFMGLPNQWARYLRWD
ASTRSDLSFQFKTNVSTGLLLYLDDGGVCDFLCLSLVDGRVQLRFSMDCAETAVLSNK
QVNDSSWHFLMVSRDRLRTVLMLDGEGQSGELQPQRPYMDVVSDLFLGGVPTDIRPSA
LTLDGVQAMPGFKGLILDLKYGNSEPRLLGSRGVQMDAEGPCGERPCENGGICFLLDG
HPTCDCSTTGYGGKLCSEGLSHLMMSEQGRSKAREENVATFRGSEYLCYDLSQNPIQS
SSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGK
FNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPG
SPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINFE
TPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAV
ELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTAS
GESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQL
AEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREAS
ILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGR
VKLMVNLGKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLE
FHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRN
IIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVK
GYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGA
KNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQ
IERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGG
LILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVF
NIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQM
VKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKV
LNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKN
RSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSARSSNAARSLRAALTWTWRLTY
TFTPIIFISCVVHS"
BASE COUNT 1582 a 1761 c 1575 g 1618 t
ORIGIN
1 cccaaagagg aaacataccc agcaaactca gttgattaaa catcaaacag acatacagac
61 agatcccaaa tcttctgttc aactggaaag gtcttttctc tggagtcctg ggaggcaagt
121 tatgggcagc actgcttctg gccgcaccat gaagcctgag tctgcttgcg ctctgcccag
181 ggccctgctc tgtctgagca ttgggcttct agctgccccc ctccccacag cctgccgctg
241 ctaggaggta gaactttagg agtggtcctt ggcctgtttc tacctgtcac ctggctcacc
301 tcaccactca ctcctcctcc atcacagcac cccggccctc cctgtccctg gcctccctgg
361 ctggggcatt tgggggtccg ctgggaggag tgcatcgctg aaggcttctt cctactctcc
421 tgcaccttct cctccttgag tcaaggcctc cggatccaca tggatagctg agatcttttc
481 ttggagaaag acgctttcct ctttactcca gtccctcact tccccacctg attttcctcc
541 tcttctgctg gtcctgtctt tttctactgc ctctttattc aatttcttgc ttgtgtgccc
601 ctctgggact ctcttgtaca ctttcctcca tctccactat ctcaggatct gtgtgtgtgc
661 tgccttcctc ctgtgtgctt tctgtccccc catctctgtc ttgtctttcc cacttctatt
721 gccaaaggga gagatcctct ccgggctgtt ccctggcctg tctgctcctc cgggctctgt
781 cccagcagcg acaatgagct ccacactcca ctcggttttc ttcaccctga aggtcagcat
841 cctgctgggg tccctgctgg ggctctgcct gggccttgag ttcatgggcc tccccaacca
901 gtgggcccgc tacctccgct gggatgccag cacacgcagt gacctgagtt tccagttcaa
961 gaccaacgtc tctacggggc tgctcctcta cctggatgat ggcggcgtct gcgacttcct
1021 atgcctctcc ctggtggatg gccgcgttca gctccgcttc agcatggact gtgccgagac
1081 tgccgtgctg tccaacaagc aggtgaatga cagcagctgg cacttcctca tggtgagccg
1141 tgaccgcctg cgcacggtgc tgatgcttga tggcgagggc cagtctgggg agctgcagcc
1201 ccagcggccc tacatggatg tggtcagtga cttgttcctt ggtggagtcc ctactgacat
1261 acgaccttct gccctgaccc ttgatggagt tcaggccatg cccggcttca aggggttaat
1321 tctggatctc aagtatggaa actcggagcc tcggcttctg gggagccggg gtgtccagat
1381 ggatgccgag ggaccctgtg gtgagcgtcc ctgtgaaaat ggtgggatct gctttctcct
1441 ggacggccac cccacctgtg actgttctac cactggctat ggtggcaagc tctgctcaga
1501 aggcctctcc cacctcatga tgagtgaaca aggtagaagt aaagctcgag aggagaatgt
1561 ggccactttc cgaggctcag agtatctgtg ctacgacctg tctcagaacc cgatccagag
1621 cagcagtgat gaaatcaccc tctcctttaa gacctggcag cgtaacggcc tcatcctgca
1681 cacgggcaag tcggctgact atgtcaacct ggctctgaag gatggtgcgg tctccttggt
1741 cattaacctg gggtccgggg cctttgaggc cattgtggag ccagtgaatg gaaaattcaa
1801 cgacaacgcc tggcatgatg tcaaagtgac acgcaacctc cggcaggtga caatctctgt
1861 ggatggcatt cttaccacga cgggctacac tcaagaggac tataccatgc tgggctcgga
1921 cgacttcttc tatgtaggag gaagcccaag taccgctgac ttgcctggct cccctgtcag
1981 caacaacttc atgggctgcc ttaaagaggt tgtttataag aataatgaca tccgtctgga
2041 gctgtctcgc ctggcccgga ttgcggacac caagatgaaa atctatggcg aagttgtgtt
2101 taagtgtgag aatgtggcca cactggaccc catcaacttt gagaccccag aggcttacat
2161 cagcttgccc aagtggaaca ctaaacgtat gggctccatc tcctttgact tccgcaccac
2221 agagcccaat ggcctgatcc tcttcactca tggaaagccc caagagagga aggatgctcg
2281 gagccagaag aatacaaaag tagacttctt tgccgtggaa ctcctcgatg gcaacctgta
2341 cttgctgctt gacatgggct ctggcaccat caaagtgaaa gccactcaga agaaagccaa
2401 tgatggggaa tggtaccatg tggacattca gcgagatggc agatcaggta ctatatcagt
2461 gaacagcagg cgcacgccat tcaccgccag tggggagagc gagatcctgg acctggaagg
2521 agacatgtac ctgggagggc tgccggagaa ccgtgctggc cttattctcc ccaccgagct
2581 gtggactgcc atgctcaact atggctacgt gggctgcatc cgcgacctat tcattgatgg
2641 gcgcagcaag aacattcgac agctggcaga gatgcagaat gctgcgggtg tcaagtcctc
2701 ctgttcacgg atgagtgcca agcagtgtga cagctacccc tgcaagaata atgctgtgtg
2761 caaggacggc tggaaccgct tcatctgcga ctgcaccggc accggatact ggggaagaac
2821 ctgcgaaagg gaggcatcca tcctgagcta tgatggtagc atgtacatga agatcatcat
2881 gcccatggtc atgcatactg aggcagagga tgtgtccttc cgcttcatgt cccagcgagc
2941 ttatgggctg ctggtggcta cgacctccag ggactctgcc gacaccctgc gtctggagct
3001 ggatgggggg cgtgtcaagc tcatggttaa cttaggcaaa ggaccagaga ccttgtatgc
3061 agggcagaag ctcaatgaca acgagtggca caccgttcgg gtggtgcgga gaggaaaaag
3121 ccttaagtta accgtggatg atgatgtggc tgagggtaca atggtgggag accatacccg
3181 tttggagttc cacaacattg aaacgggaat catgactgag aaacgctaca tctccgttgt
3241 cccctccagc tttattggcc atctgcagag cctcatgttt aatggccttc tctacattga
3301 cttgtgcaaa aatggtgaca ttgattattg tgagctgaag gctcgttttg gactgaggaa
3361 catcatcgct gaccctgtca cctttaagac caagagcagc tacctgagcc ttgccactct
3421 tcaggcttac acctccatgc acctcttctt ccagttcaag accacctcac cagatggctt
3481 cattctcttc aatagtggtg atggcaatga cttcattgca gtcgagcttg tcaaggggta
3541 tatacactac gtttttgacc tcggaaacgg tcccaatgtg atcaaaggca acagtgaccg
3601 ccccctgaat gacaaccagt ggcacaatgt cgtcatcact cgggacaata gtaacactca
3661 tagcctgaaa gtggacacca aagtggtcac tcaggttatc aatggtgcca aaaatctgga
3721 tttgaaaggt gatctctata tggctggtct ggcccaaggc atgtacagca acctcccaaa
3781 gctcgtggcc tctcgagatg gctttcaggg ctgtctagca tcagtggact tgaatggacg
3841 cctgccagac ctcatcaatg atgctcttca tcggagcgga cagatcgagc gtggctgtga
3901 aggacccagt accacctgcc aggaagattc atgtgccaac cagggggtct gcatgcaaca
3961 atgggagggc ttcacctgtg attgttctat gacctcttat tctggaaacc agtgcaatga
4021 tcctggcgct acgtacatct ttgggaaaag tggtgggctt atcctctaca cctggccagc
4081 caatgacagg cccagcacgc ggtctgaccg ccttgccgtg ggcttcagca ccactgtgaa
4141 ggatggcatc ttggtccgca tcgacagtgc tccaggactt ggtgacttcc tccagcttca
4201 catagaacag gggaaaattg gagttgtctt caacattggc acagttgaca tctccatcaa
4261 agaggagaga acccctgtaa atgacggcaa ataccatgtg gtacgcttca ccaggaacgg
4321 cggcaacgcc accctgcagg tggacaactg gccagtgaat gaacattatc ctacaggcaa
4381 cactgataat gaacgcttcc aaatggtaaa acagaaaatc cccttcaaat ataatcggcc
4441 tgtagaggag tggctgcagg aaaaaggccg gcagttaacc atcttcaaca ctcaggcgca
4501 aatagccatt ggtggaaagg acaaaggacg cctcttccaa ggccaactct ctgggctcta
4561 ttatgatggt ttgaaagtac tgaacatggc ggctgagaac aaccccaata ttaaaatcaa
4621 tggaagtgtt cggctggttg gagaagtccc atcaattttg ggaacaacac agacgacctc
4681 catgccacca gaaatgtcta ctactgtcat ggaaaccact actacaatgg cgactaccac
4741 aacccgtaag aatcgctcta cagccagcat tcagccaaca tcagatgatc ttgtttcatc
4801 tgctgaatgt tcaagtgatg atgaagactt tgttgaatgt gagccgagta caggtaggtc
4861 agccagaagc tctaatgcag ctagatcact ccgtgccgcc cttacatgga catggcgact
4921 cacttacaca tttactccta tcatcttcat ctcctgtgta gttcactcat agatatgacc
4981 ctccccttcc tgcatctttc cttcccattc tccccctttc tttagcattg ttaaaattta
5041 tgtgctgtca tccatctccc taaattaaag aaagcctaaa atttgtcaaa aagacaaaaa
5101 aatatatata tctgaaaact tataaatgca gaaattcatt caaaacccgt tagagtcata
5161 gaattttttg aaaggcaaat tataaaagta aacaggtttt tttgtttggt ttttcaatca
5221 tagcaatcgg aattatttta aattcaaaaa ttgatgccct cccaaacccc ccaaagtaaa
5281 aatttgttaa agtgcagatt ttttttttct ttttatgtta tgtggtgtgg atgtatgtgt
5341 tgttgcctcc ctgtatcatc ctctgttgta aattattata tttgaaaaat tagacatttt
5401 gctcaaaagt ttttaagaaa tgacaacaaa aaaagcaagt tacaagaatg tggcaattct
5461 atttgtccaa gagcattctt acacaacttt cttttgtaaa tttttctttc atgccaaaaa
5521 acatgcgggc aatttgttga tgaggtgaat tagttatccc tcttcttgta gaagaccctt
5581 tagctacccc tcctattgct actcgtgcac cttccattac actcccccct acctttcgcc
5641 ccctcctcac cattattgag accaccaaag attccctgtc catgacctct gaggcggggt
5701 taccttgctt gtcggaccaa ggcagcgatg gttgtgatga tgatggcttg gtgatatctg
5761 ggtatggctc aggggaaacc tttgactcta acctgccccc tactgatgat gaagattttt
5821 acaccacctt ctccttggta acagataaga gtctttccac ttcaatcttc gaaggtggct
5881 acaaagcaca tgcgcccaag tgggaatcca aggactttag acctaacaaa gtctccgaaa
5941 ctagtaggac tactaccaca tctttatccc ctgagctgat ccgcttcaca gcttcctcct
6001 cgtctgggat ggtgcccaaa ttgccagctg gcaaaatgaa taaccgtgat ctcaaacccc
6061 agcctgatat agtcttgctt ccgttgccca ctgcctatga gctagacagc accaaactga
6121 agagcccact aattacttcc cccatgttcc gtaatgtgcc cacagcaaac cccacggagc
6181 cgggaatcag acgggttccg ggggcctcag aggtgatccg ggagtcgagc agcacaacag
6241 ggatggtcgt cggcattgtg gctgctgccg ccctctgcat cttgatcctc ctgtacgcca
6301 tgtacaagta caggaacagg gacgaggggt cctatcaagt ggacgagacg cggaactaca
6361 tcagcaactc cgcccagagc aacggcacgc tcatgaagga gaagcagcag agctcgaaga
6421 gcggccacaa gaaacagaaa aacaaggaca gggagtatta cgtgtaaaca tgcgaacact
6481 gctcacacgc gagttttcac agttatttct atccacgcct atgaatcttt ggacgg
//