LOCUS       AJ314834                 285 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  Homo sapiens mRNA for beta-defensin 4 (DEFB4 gene).
ACCESSION   AJ314834
VERSION     AJ314834.1
KEYWORDS    DEFB4 gene; human beta-defensin 4.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Krause A.
  JOURNAL   Submitted (05-JUN-2001) to the INSDC. Krause A., Molecular Biology,
            IPF PharmaCeuticals GmbH, Feodor-Lynen-Str. 31, Hannover, Lower
            Saxony, D-30625, GERMANY.
REFERENCE   2
  AUTHORS   Conejo-Garcia J.R., Krause A., Schulz S., Rodriguez-Jimenez F.J.,
            Kluever E., Adermann K., Forssmann U., Frimpong-Boateng A.,
            Bals R., Forssmann W.G.
  TITLE     Human beta-defensin 4: a novel inducible peptide with a specific
            salt-sensitive spectrum of antimicrobial activity
  JOURNAL   FASEB J. 10, 1819-1821(2001).
FEATURES             Location/Qualifiers
     source          1..285
                     /db_xref="H-InvDB:HIT000247150_04"
                     /organism="Homo sapiens"
                     /chromosome="8"
                     /mol_type="mRNA"
                     /dev_stage="adult"
                     /tissue_type="lung"
                     /db_xref="taxon:9606"
     5'UTR           1..14
                     /gene="DEFB4"
     CDS             15..233
                     /gene="DEFB4"
                     /product="beta-defensin 4"
                     /function="antimicrobial peptide"
                     /db_xref="GOA:Q8WTQ1"
                     /db_xref="H-InvDB:HIT000247150_03.4"
                     /db_xref="HGNC:HGNC:18115"
                     /db_xref="HGNC:HGNC:26165"
                     /db_xref="InterPro:IPR025933"
                     /db_xref="PDB:5KI9"
                     /db_xref="UniProtKB/Swiss-Prot:Q8WTQ1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /protein_id="CAC85511.1"
                     /translation="MQRLVLLLAVSLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQ
                     EYRIGRCPNTYACCLRKWDESLLNRTKP"
     sig_peptide     15..80
                     /gene="DEFB4"
     mat_peptide     81..230
                     /gene="DEFB4"
                     /product="beta-defensin 4"
BASE COUNT           80 a           61 c           72 g           72 t
ORIGIN      
        1 gcagccccag cattatgcag agacttgtgc tgctattagc cgtttctctt ctactctatc
       61 aagatcttcc agtgagaagc gaatttgaat tggacagaat atgtggttat gggactgccc
      121 gttgccggaa gaaatgtcgc agccaagaat acagaattgg aagatgtccc aacacctatg
      181 catgctgttt gagaaaatgg gatgagagct tactgaatcg tacaaaaccc tgaaacgcag
      241 tagtgctggt ccctagagtc gctggaagta ggacctcagt agctt
//