LOCUS AJ314834 285 bp mRNA linear HUM 07-OCT-2008 DEFINITION Homo sapiens mRNA for beta-defensin 4 (DEFB4 gene). ACCESSION AJ314834 VERSION AJ314834.1 KEYWORDS DEFB4 gene; human beta-defensin 4. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 285) AUTHORS Krause A. JOURNAL Submitted (05-JUN-2001) to the INSDC. Krause A., Molecular Biology, IPF PharmaCeuticals GmbH, Feodor-Lynen-Str. 31, Hannover, Lower Saxony, D-30625, GERMANY. REFERENCE 2 AUTHORS Conejo-Garcia J.R., Krause A., Schulz S., Rodriguez-Jimenez F.J., Kluever E., Adermann K., Forssmann U., Frimpong-Boateng A., Bals R., Forssmann W.G. TITLE Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity JOURNAL FASEB J. 10, 1819-1821(2001). FEATURES Location/Qualifiers source 1..285 /db_xref="H-InvDB:HIT000247150_04" /organism="Homo sapiens" /chromosome="8" /mol_type="mRNA" /dev_stage="adult" /tissue_type="lung" /db_xref="taxon:9606" 5'UTR 1..14 /gene="DEFB4" CDS 15..233 /gene="DEFB4" /product="beta-defensin 4" /function="antimicrobial peptide" /db_xref="GOA:Q8WTQ1" /db_xref="H-InvDB:HIT000247150_03.4" /db_xref="HGNC:HGNC:18115" /db_xref="HGNC:HGNC:26165" /db_xref="InterPro:IPR025933" /db_xref="PDB:5KI9" /db_xref="UniProtKB/Swiss-Prot:Q8WTQ1" /experiment="experimental evidence, no additional details recorded" /protein_id="CAC85511.1" /translation="MQRLVLLLAVSLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQ EYRIGRCPNTYACCLRKWDESLLNRTKP" sig_peptide 15..80 /gene="DEFB4" mat_peptide 81..230 /gene="DEFB4" /product="beta-defensin 4" BASE COUNT 80 a 61 c 72 g 72 t ORIGIN 1 gcagccccag cattatgcag agacttgtgc tgctattagc cgtttctctt ctactctatc 61 aagatcttcc agtgagaagc gaatttgaat tggacagaat atgtggttat gggactgccc 121 gttgccggaa gaaatgtcgc agccaagaat acagaattgg aagatgtccc aacacctatg 181 catgctgttt gagaaaatgg gatgagagct tactgaatcg tacaaaaccc tgaaacgcag 241 tagtgctggt ccctagagtc gctggaagta ggacctcagt agctt //