LOCUS AJ310931 8565 bp mRNA linear HUM 21-OCT-2008
DEFINITION Homo sapiens mRNA for myosin heavy chain (MYO18B gene).
ACCESSION AJ310931
VERSION AJ310931.2
KEYWORDS heavy chain; myosin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Salamon M.
JOURNAL Submitted (09-APR-2001) to the INSDC. Salamon M., Biology,
University of Padova, via U. Bassi, 58/B Padova, 35134, ITALY.
REMARK revised by [3]
REFERENCE 2
AUTHORS Salamon M., Millino C., Raffaello A., Mongillo M., Sandri C.,
Bean C., Negrisolo E., Pallavicini A., Valle G., Zaccolo M.,
Schiaffino S., Lanfranchi G.
TITLE Human MYO18B, a novel unconventional myosin heavy chain expressed
in striated muscles moves into the myonuclei upon differentiation
JOURNAL J. Mol. Biol. 326(1), 137-149(2003).
PUBMED 12547197
REFERENCE 3 (bases 1 to 8565)
AUTHORS Salamon M.
JOURNAL Submitted (15-APR-2002) to the INSDC. Salamon M., Biology,
University of Padova, via U. Bassi, 58/B Padova, 35134, ITALY.
FEATURES Location/Qualifiers
source 1..8565
/db_xref="H-InvDB:HIT000247087"
/organism="Homo sapiens"
/chromosome="22"
/mol_type="mRNA"
/tissue_type="skeletal muscle"
/db_xref="taxon:9606"
CDS 251..7954
/gene="MYO18B"
/product="myosin heavy chain"
/db_xref="GOA:Q8IUG5"
/db_xref="H-InvDB:HIT000247087.13"
/db_xref="HGNC:HGNC:18150"
/db_xref="InterPro:IPR000048"
/db_xref="InterPro:IPR001609"
/db_xref="InterPro:IPR027401"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR028561"
/db_xref="InterPro:IPR036064"
/db_xref="InterPro:IPR036961"
/db_xref="UniProtKB/Swiss-Prot:Q8IUG5"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAC70712.2"
/translation="MAMSSRLALWEQKIREEDKSPPPSSPPPLFSVIPGGFIKQLVRG
TEKEAKEARQRKQLAVASPEREIPEISISQPNSKSSSGTRSGSQQISQDDQSSSPGSS
DILGKESEGSRSPDPEQMTSINGEKAQELGSSATPTKKTVPFKRGVRRGDVLLMVAKL
DPDSAKPEKTHPHDAPPCKTSPPATDTGKEKKGETSRTPCGSQASTEILAPKAEKTRT
GGLGDPGQGTVALKKGEEGQSIVGKGLGTPKTTELKEAEPQGKDRQGTRPQAQGPGEG
VRPGKAEKEGAEPTNTVEKGNVSKDVGSEGKHVRPQIPGRKWGGFLGRRSKWDGPQNK
KDKEGVLLSKAEKTGEPQTQMEKTSQVQGELGDDLRMGEKAGELRSTTGKAGESWDKK
EKMGQPQGKSGNAGEARSQTEKGCEAPKEVSTMVESPAAPGKGGWPGSRGQEAEEPCS
RAGDGAGALETELEGPSQPALEKDAERPRIRKENQDGPAPQEEGKGGQSRDSDQAPED
RWYEAEKVWLAQKDGFTLATVLKPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRAN
PPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSVPSAGKV
PKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAG
SVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQTML
LEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSKPEDKQK
AAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWANYAA
EALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVEGMASG
LYQELFAAVVLLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEELCHNYAH
ERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQ
DARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQ
LGWDPVRYDLTGWLHRAKPNLSALDAPQVLXQSKREELRSLFQARAKLPPVCRAVAGL
EGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVP
NPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYAD
HMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFL
KAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLA
VKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLE
SKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQ
LEEAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKE
LEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFD
LQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDH
KRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIE
RMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGT
LCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQ
SEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQ
DDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQS
TVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQ
QRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSI
RRIADLQAALEEVASSDSDTESVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLSCT
LSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDK
PVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSA
ALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPIYQTTGASTLRRGRAGSDEGNLSLRVG
AKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRK
LSSPTTPRDMLLSPTLRPRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSD
PFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGSAKGGQDGSQRSSIHFETEEA
NRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGG
ERTSPERREPGTGRKDDDVASIMKKYLQK"
regulatory 8146..8151
/gene="MYB018B"
/regulatory_class="polyA_signal_sequence"
regulatory 8542..8547
/gene="MYO18B"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 2097 a 2266 c 2663 g 1538 t
ORIGIN
1 gggaagggat gtgtgtcggt gtgtgtggag agggtgctcc ttcgctcctg ctttcccggc
61 tcggtggggt cccttcgcgg ccacccgggg agacgtctta gacagtcgtg gttcctgtga
121 tctgtgtcct ctttgcagaa gttctgtgtc catctcatgt gctgcgtgtg tctgtaaagc
181 ctcattccgt gctgtctggc aggaagctcc atctcatctc atcatctcac ggccctggca
241 ctgcctcagc atggccatgt catcacgcct cgccctgtgg gagcagaaga ttcgggaaga
301 ggacaagagc cctccaccat cctcgccccc tcctcttttc tctgtcatcc cagggggctt
361 cattaagcaa ctggtccggg ggactgaaaa agaggccaag gaagcgagac agaggaagca
421 gttagctgtc gcctctccag aacgagagat cccagaaatt tccatcagcc aacccaacag
481 caagtccagc agtggcacca gatctggaag ccagcagatc tctcaggacg accagtcaag
541 ctctcctggg agctcagaca ttctgggcaa ggagagcgag gggtcccgca gccccgaccc
601 tgagcagatg acaagcatca atggtgagaa ggcccaggag ctgggctcca gtgcgacacc
661 aaccaaaaag actgtcccct tcaagagggg cgtgaggagg ggtgatgtgt tgttgatggt
721 ggccaagctg gacccggact cagccaagcc agagaagact catccccatg acgccccccc
781 ttgcaagacc tctccccccg ccacagatac tggaaaggaa aagaaagggg agacctctag
841 gactccttgt ggctcccagg ccagcaccga gatcttggcc ccgaaagctg agaagacccg
901 gactgggggt cttggggacc caggccaagg aactgtggca ctgaaaaaag gcgaggaggg
961 tcaaagcata gtggggaagg ggcttgggac ccccaagacc acagagctga aagaggctga
1021 gccccagggc aaagacaggc aggggaccag gccccaagcc caagggcccg gcgagggggt
1081 gcgaccaggg aaagcagaga aggagggagc agagcccaca aacacggtgg aaaaggggaa
1141 tgtctctaag gacgtaggga gtgaagggaa gcacgtaagg ccccaaatcc ctgggagaaa
1201 gtggggaggt ttcctgggaa gaaggagtaa gtgggacggt ccccagaata agaaggacaa
1261 agaaggggtg ctcttaagta aggcagagaa gacaggtgag cctcagaccc agatggagaa
1321 gacaagccaa gtgcagggcg agttggggga cgatctgaga atgggggaga aagcaggtga
1381 gcttcggagc acgactggga aggcaggtga gtcctgggat aagaaggaaa agatggggca
1441 accccagggt aagtccggga acgcaggtga agctcggagt cagacagaga agggctgtga
1501 agccccaaag gaggtgagca caatggtgga gtcgccagca gctcctggga agggaggctg
1561 gccaggaagc cgtgggcagg aagcagagga gccctgctca agagcaggtg atggggctgg
1621 tgccctggag acagagctgg aaggacccag ccagcctgct ctggagaagg atgcagaaag
1681 gcctcggata cggaaggaga accaagacgg gccagccccg caggaggagg gcaaaggagg
1741 ccagagcaga gactcagacc aggctcctga ggacagatgg tatgaggcag agaaagtctg
1801 gctggctcag aaggatggat ttactcttgc tacggtgcta aagccagatg agggaacagc
1861 agacctgcca gcaggaaggg tgagactttg gattgatgct gacaaaacca tcactgaggt
1921 ggatgaggag catgtccatc gggccaaccc tcctgagctg gaccaggtcg aggacctggc
1981 ctctctcatc agtgtcaacg aatccagtgt cctgaacacg cttctgcagc gctacaaagc
2041 tcagctgctg cacacctgca cagggcctga tctgattgtc ctccagcccc gggggccctc
2101 ggtgccttct gcagggaagg tgcccaaggg ccgccgggat ggcctgcctg cccacattgg
2161 ctccatggca cagcgggcat actgggcgct gctgaaccag cggagagacc agagcattgt
2221 ggccctgggc tggagtggcg ctgggaagac cacctgctgt gagcaggtcc tggaacacct
2281 ggtggggatg gcaggcagtg tggatggcag ggtctcagtg gagaagatcc gagccacctt
2341 cactgtcctc cgggccttcg gctctgtgtc catggcccac agccgcagtg ccacccggtt
2401 ctccatggtg atgtcgctgg acttcaacgc tacaggccgc atcacagctg ctcagctcca
2461 gacaatgctt ttggagaaga gccgcgtggc acggcagccg gaaggggaaa gtaacttcct
2521 ggttttctcc cagatgctgg ctggattgga cttggatctc aggacggagc tgaacctgca
2581 ccagatggca gatagcagct cctttggcat gggcgtgtgg tccaagcctg aagataaaca
2641 gaaggcggca gctgcctttg cccagctcca gggtgccatg gagatgctcg gcatctcaga
2701 gagcgagcag cgggctgttt ggcgggtcct ggcagccatc taccacctgg gtgcggcggg
2761 ggcctgcaaa gtgggtcgga agcagttcat gaggtttgag tgggcaaact acgcagctga
2821 ggccctgggc tgcgagtatg aggagctgaa cacggccacc ttcaagcacc accttcgaca
2881 gatcatccag caaatgacgt ttgggccaag ccgatggggc ctcgaggatg aggaaaccag
2941 ctcagggctc aagatgacag gagtggactg tgtggagggg atggcctcgg gcctgtacca
3001 ggaactcttt gcggctgtgg tcttactcat caacagatcc ttttcctccc accatctctc
3061 catggcctcc atcatggtgg tggactctcc aggcttccag aacccccggc accagggcaa
3121 ggaccgggcg gccacctttg aggagctgtg ccacaactac gcccatgagc gcctgcagct
3181 gctgttctac cagcggacct ttgtctccac gctacagcga tatcaagagg aaggtgttcc
3241 tgtgcagttt gacctcccgg acccctcccc agggaccacc gtggctgttg tggatcaaaa
3301 tccctctcag gtccgcttac cagctggagg aggtgcccag gatgccagag gccttttctg
3361 ggtcttagat gaggaagtcc atgtagaggg ctccagtgac agtgtggtgc tcgagcgtct
3421 gtgtgctgct ttcgagaaga aaggagctgg gactgaaggg tcctctgccc tgcggacctg
3481 tgagcagccc ctccagtgtg agattttcca ccagttggga tgggaccctg tgcggtacga
3541 cctcacgggc tggctccaca gagccaagcc caacctctcg gccctggatg caccccaggt
3601 cctgcamcag tcaaaaagag aggagctgcg gagtctattc caggcccggg ccaagctgcc
3661 tcctgtgtgc cgggctgtgg caggcctgga gggcacctcc cagcaggccc tgcagaggag
3721 ccgcatggtg aggaggacct ttgccagcag ccttgccgcg gtgaggagga aagccccgtg
3781 ctcccagatc aagctgcaga tggatgcgct gaccagcatg atcaaaaggt cccggctgca
3841 ctttatccac tgcctggtac caaaccctgt ggtggaaagc aggagtgggc aggaatctcc
3901 accaccaccg cagcctggta gagacaagcc tggggcaggt ggacctctgg ccctggatat
3961 cccagcactg agggtccagc ttgctgggtt ccacatcctg gaggctctgc gtctgcatag
4021 gacaggctat gctgaccaca tggggctcac tcgcttccgc cggcaattcc aggtgctgga
4081 cgctccactc ctgaagaagc tcatgtcgac ctccgaggga atagatgaaa ggaaggccgt
4141 ggaggagctc ctggagaccc tggatctgga aaagaaggcg gtggctgtgg ggcacagcca
4201 agtttttctc aaggcaggtg tgatctccag gcttgagaag cagcgagaga agctggtatc
4261 tcagagcatc gttctcttcc aggcggcttg caagggcttt ctgtctcgcc aggaattcaa
4321 gaagctgaag attcgccgac tggctgcaca gtgcatccag aagaatgtgg ctgtgttcct
4381 cgcagtcaag gactggccat ggtggcagct gcttggttcc ctccagcctc tacttagtgc
4441 caccattgga actgagcagc tccgagccaa ggaggaggag cttacaacgc taagacggaa
4501 gctagaaaaa tcagagaagt tgcggaatga actccggcag aacacagatc tgctagaaag
4561 caagattgct gacttgacct ctgaccttgc cgatgagcgc ttcaaaggtg atgtggcctg
4621 ccaggtgctg gagagtgagc gggcagagcg gctacaggcc ttccgggagg tccaggagct
4681 caagagcaag catgaacaag tccagaaaaa actgggagat gtgaataaac agttggaaga
4741 agcccagcag aaaattcagt tgaatgactt ggaaaggaat cccactggag gagcagacga
4801 gtggcagatg cgcttcgact gtgctcagat ggagaacgag ttcctcagaa agcgtctgca
4861 gcaatgcgag gagaggctgg actcggagct gacagccagg aaagagctgg agcaaaagct
4921 tggggagttg caaagtgctt atgacggggc caagaagatg gctcaccaac tgaagaggaa
4981 gtgccaccat cttacctgtg accttgagga tacctgcgtc ctgctagaga accaacaaag
5041 tcgaaaccat gagctggaga agaagcagaa gaagtttgac ctgcagctgg cccaggccct
5101 aggtgagtca gtgtttgaga agggtctccg tgagaaagtg acccaggaga acaccagtgt
5161 ccggtgggag ctaggccagc ttcagcagca gctgaagcaa aaggagcagg aagcctcaca
5221 gctgaagcag caggtggaga tgctacagga ccataaacgg gagctgctgg ggtcaccctc
5281 tctgggggaa aattgcgttg ctggcttgaa ggagaggctc tggaagttgg aatccagcgc
5341 ccttgagcaa cagaaaatcc agagccagca ggaaaacacc atcaagcagc tggagcagct
5401 ccgccagcgg tttgagctgg agatcgagcg gatgaagcag atgcaccaga aggaccgtga
5461 ggaccaggag gaggaactgg aggatgtccg tcagtcctgc cagaagcggc ttcatcagct
5521 ggaaatgcag ctggagcaag agtatgaaga gaagcagatg gtcctccatg agaagcaaga
5581 tttggaaggc ttgatcggaa ccctctgtga ccagattggc catcgggact ttgatgtgga
5641 gaagcgactt cggagagacc tcaggaggac acatgcactg ttgtcagacg tgcagctcct
5701 tctgggcacc atggaggatg gcaagacatc agtcagcaag gaggagctgg agaaagtgca
5761 cagccagctg gagcagagtg aagccaagtg tgaggaggcc ttgaagacgc agaaggtgct
5821 cacagcggac ctggagagca tgcacagcga gctggagaac atgacgcgga acaagagcct
5881 ggtggatgag cagctgtaca ggctgcagtt tgagaaggcg gacctcctga agcgcatcga
5941 tgaggaccag gatgacctga atgagctgat gcagaagcac aaggacctca ttgctcagtc
6001 tgctgctgac attgggcaga tccaagaact gcagctgcag ctggaggaag ccaagaagga
6061 gaagcacaag ctacaagaac aactgcaggt ggctcagatg cgcatcgagt acctggaaca
6121 gtccaccgtg gatcgagcca tcgtcagcag gcaggaggcg gtcatctgtg acctagagaa
6181 caagacagag ttccagaagg tgcagattaa gagatttgag gtcctggtga tccggcttcg
6241 ggacagcctg atcaagatgg gggaggagct ttcacaggcg gccacctccg agtcccagca
6301 gcgggagagc agccagtact accagcggcg cctggaagag ctgaaggccg acatggaaga
6361 gctggtgcag cgggaggcag aggccagccg gcggtgcatg gagctggaga agtacgtgga
6421 ggaacttgca gcagtgaggc aaaccctcca gacagacctg gagacatcca ttcggcggat
6481 tgccgacctg caggctgcct tggaagaagt ggcatccagt gacagtgata ctgagagtgt
6541 ccagacggca gtggattgtg gcagcagcgg ccgaaaagag atggataacg tctccatcct
6601 cagctcccag ccagagggca gcctgcagtc ctggttgagc tgtactctgt ccctggccac
6661 agatactatg aggactcctt ctcgacagtc agccaccagc agccgcatcc tcagccccag
6721 gataaacgaa gaggctgggg acactgagag gacccagtcg gcattggcac tgagcagagc
6781 ccggtccacc aatgtccaca gcaagacctc aggagacaag cctgtttctc cccactttgt
6841 ccgccggcaa aagtactgtc attttgggga cggcgaagtg cttgccgtcc agagaaagtc
6901 cacagagaga ttagaacctg cttcctctcc cctggcttct cggagtacaa atacatcccc
6961 gctgtcgagg gaaaagctgc ccagtccttc agcggccctc tcggagttcg tggaagggct
7021 ccggaggaag agagcccaga gaggccaggg gtccacgctg ggcctagagg actggcccac
7081 tctccccatt taccagacga ctggggcctc cacactaagg aggggcaggg ctggcagtga
7141 cgagggaaac ctctcgctga gggttggggc aaagtcaccc ctggaaatcg aaggggccgc
7201 tggtggtctc ttgaggtcca ccagcctcaa atgcatctct tcagacggtg ttgggggcac
7261 aaccctactc cccgaaaagt cgaaaaccca attcagttcc tgcgagtccc tcttagaatc
7321 cagaccgagc atggggagaa aactgagctc tccgaccaca cccagggaca tgctgttgtc
7381 gcccacactg cgtcctcgga ggcggtgtct ggagtcctct gtggacgatg cgggctgtcc
7441 agaccttgga aaggagccgc ttgttttcca gaaccgccag tttgcccacc tgatggagga
7501 acctctaggc agtgacccat tcagctggaa actcccaagc ctcgactacg aacgcaagac
7561 caaagtggac ttcgatgact tcctcccagc tatccggaag ccccagacac ctacctcctt
7621 ggctggatca gccaaaggtg ggcaagacgg ttcacagcgt tcaagcatcc actttgaaac
7681 ggaagaggct aaccgttcct ttctctcggg gatcaagacc attttgaaga agagcccgga
7741 gcccaaggag gatcccgctc acctgtctga ctcgtcctca tcctccggct ccatcgtgtc
7801 cttcaaaagt gctgacagca tcaaaagtcg accaggaatc ccacgacttg cgggtgacgg
7861 tggcgagcga acgtcccccg agcggagaga gccagggacg gggaggaaag acgacgatgt
7921 tgcgagcata atgaagaaat acctccagaa gtaggaacca gttcagcctc cttgaagctg
7981 cccttgaaga cttcccgact ctacaataac ttggagacag agagactggc caggcctccc
8041 cggtggccag agccagccag catggccacc ctcaagaggc gagatgagcc cacagaggca
8101 tatcctgcgg ggatgctggg ctcccagtgt ggttggcctg aacaaaataa agtgttgact
8161 cctgggcatc tgtgccttct ctatggcctt gctacctggg attccagaga gttgatgggg
8221 tgcagatagg ggtaggactg ttagaataga accaacccaa actgtgtgta gtttggggtg
8281 tatacttcta tttctcttcc tacatgtcta catgccatga ccttcctcct cctcttcact
8341 tggccagttt cagctcactt cctccaggaa gtctttcctg atatatcaaa ctgaaacaaa
8401 tgctcctcct ccatgctccc ttaatcccca tgcttgtcga ttatattcct ttgccaattc
8461 atttctctat cctgtgtatg tataagtgtg tacaagcatt caagaaactg atgaatgatg
8521 aatgaatgaa tgagccaaag aacaaataaa tgagcccaca caccc
//