LOCUS AJ308599 2255 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for keratin 6 irs (KRT6IRS gene).
ACCESSION AJ308599
VERSION AJ308599.1
KEYWORDS cytokeratin type II; keratin 6 irs; KRT6IRS gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2255)
AUTHORS Rogers M.A.
JOURNAL Submitted (02-MAR-2001) to the INSDC. Rogers M.A., Research Program
B (b0501), German Cancer Research Center, Im Neuenheimer Feld 280,
Baden-Wuerrtemberg, 69120, GERMANY.
REFERENCE 2
AUTHORS Rogers M.A., Langbein L., Winter H., Praetzel S., Ehmann C.,
Schweizer J.
TITLE K6irs, a new cytokeratin in the human hair follicle
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..2255
/db_xref="H-InvDB:HIT000247026"
/organism="Homo sapiens"
/chromosome="12"
/mol_type="mRNA"
/clone="scl247"
/tissue_type="scalp"
/db_xref="taxon:9606"
CDS 43..1614
/gene="KRT6IRS"
/product="keratin 6 irs"
/function="structure protein"
/note="type II cytokeratin specific to the inner root
sheath of the hair follicle"
/db_xref="GOA:Q3SY84"
/db_xref="H-InvDB:HIT000247026.13"
/db_xref="HGNC:HGNC:28927"
/db_xref="InterPro:IPR003054"
/db_xref="InterPro:IPR018039"
/db_xref="InterPro:IPR032444"
/db_xref="InterPro:IPR039008"
/db_xref="InterPro:IPR042180"
/db_xref="UniProtKB/Swiss-Prot:Q3SY84"
/protein_id="CAC43429.1"
/translation="MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFG
SRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGI
HQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLET
KWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKK
RYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQI
QSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAA
GRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARA
KLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSP
VSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTL
GKGSSLSAPSKKTSR"
regulatory 2219..2224
/gene="KRT6IRS"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 531 a 663 c 643 g 418 t
ORIGIN
1 ccttcctccc tcctgcatct gagctttgtc tccaccagca acatgagccg ccaattcacc
61 tgcaagtcgg gagctgccgc caaggggggc ttcagtggct gctcagctgt gctctcaggg
121 ggcagctcat cctccttccg ggcagggagc aaagggctca gtgggggctt tggcagccgg
181 agcctctaca gcctgggggg tgtccggagc ctcaatgtgg ccagtggcag cgggaagagt
241 ggaggctatg gatttggccg gggccgggcc agtggctttg ctggaagcat gtttggcagt
301 gtggccctgg ggcctgtgtg cccaactgta tgcccacctg gaggcatcca ccaggttacc
361 gtcaatgaga gcctcctggc ccccctcaac gtggagctgg accccgagat ccagaaagtg
421 cgtgcccagg agcgagagca gatcaaggct ctgaacaaca agttcgcctc cttcatcgac
481 aaggtgcggt tcctggagca gcagaaccag gtactggaga ccaagtggga gctgctgcag
541 cagctggacc tgaacaactg caagaacaac ctggagccca tcctcgaggg ctacatcagc
601 aacctgcgga agcagctgga gacgctgtct ggggacaggg tgaggctgga ctcggagctg
661 aggaatgtgc gggacgtagt ggaggactac aagaagaggt atgaggagga aatcaacaag
721 cggacagcag cagagaacga gtttgtgctg ctcaagaagg atgtggatgc tgcttacgcc
781 aataaggtgg aactgcaggc caaggtggaa tccatggacc aggagatcaa gttcttcagg
841 tgtctctttg aagccgagat cactcagatc cagtcccaca tcagtgacat gtctgtcatc
901 ctgtccatgg acaacaaccg gaacctagac ctggacagca tcattgacga agtccgcacc
961 cagtatgagg agattgcctt gaagagtaag gccgaggctg aggccctgta ccagaccaag
1021 ttccaagagc ttcagctggc agctggcagg catggggacg acctcaaaaa caccaagaat
1081 gaaatctcgg agctcactcg gctcatccag agaatccgct cagagatcga gaacgtgaag
1141 aagcaggctt ccaacctgga gacagccatc gctgatgctg agcagcgggg agacaacgcc
1201 ctgaaggatg cccgggccaa gctggacgag ctggagggcg ccctgcacca ggccaaggag
1261 gagctggcgc ggatgctgcg cgagtaccag gagctcatga gcctgaagct ggccctggac
1321 atggagatcg ccacctatcg caagctactg gagagcgagg agtgcaggat gtcaggagaa
1381 tttccctccc ctgtcagcat ctccatcatc agcagcacca gtggcggcag tgtctatggc
1441 ttccggccca gcatggtcag cggtggctat gtggccaaca gcagcaactg catctctgga
1501 gtgtgcagcg tgagaggcgg ggagggcagg agccggggca gtgccaacga ttacaaagac
1561 accctaggga agggttccag cctgagtgca ccctccaaga aaaccagtcg gtagagaaga
1621 ctgccccggg ccccgcctca ttccatgacc cggctctgga tcccacactg tacttcccac
1681 agcccactct cagctccatc tccaccctgc tggtcctgct cccatacacc tggcactggc
1741 cttggccacc cacttctccc agcctgtgtc ttcctgatcc tgggaaggcc tggatgacca
1801 agcttggtga aattcctccc tgtacacacc ctattaactc cttggctgtg gtcccccagc
1861 tacaccacca gcccaggtcc tggctgccag ctttcctcct ctgcccggcc tctagcgcag
1921 tcgctaacta ctctgctggg ctccctgggt ctctgcccaa ggccccgcac acactgggac
1981 ctagcatagt tcctgcctat gccaggagct ggctctgtgt ttaagaaaag gaggactgaa
2041 ggacaaacaa ccaagagtgg cccagtcccc acccccacat ctagctcagt ctcaaatctg
2101 agtgggacca agtgcaattc agggcctttt tctccactca cctgcaccca gaagcagaga
2161 aaagcaggca ctgttcactt ttcctttatt cttaatggcc ttcctctgtt gcaacctcaa
2221 taaacagcac aatctcaaaa aaaaaaaaaa aaaaa
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