LOCUS AJ297406 2065 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for transcription factor II B-related factor,
isoform 2 (BRF gene).
ACCESSION AJ297406
VERSION AJ297406.1
KEYWORDS alternative splicing; BRF gene; TFIIB-related factor 2;
transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2065)
AUTHORS Lobo-Ruppert S.M.
JOURNAL Submitted (04-JUL-2000) to the INSDC. Lobo-Ruppert S.M.,
Biochemistry and Molecular Genetics, University of Alabama at
Birmingham, 844 BBRB, 845 19th Street South, Birmingham, AL 35294,
USA.
REFERENCE 2
AUTHORS McCulloch V., Hardin P., Peng W., Ruppert J.M., Lobo-Ruppert S.M.
TITLE Alternatively spliced hBRF variants function at different RNA
polymerase III promoters
JOURNAL EMBO J. 19(15), 4134-4143(2000).
PUBMED 10921893
FEATURES Location/Qualifiers
source 1..2065
/db_xref="H-InvDB:HIT000246739"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone="lambda zap express pBKCMV"
/cell_line="MCF7, T47D, ZR75-1, MDAMB-453"
/cell_type="breast cancer"
/db_xref="taxon:9606"
CDS 1438..1842
/gene="BRF"
/product="transcription factor II B-related factor"
/function="RNA polymerase III transcription of U6 snRNA
gene"
/note="isoform 2"
/db_xref="GOA:Q92994"
/db_xref="H-InvDB:HIT000246739.12"
/db_xref="HGNC:HGNC:11551"
/db_xref="InterPro:IPR000812"
/db_xref="InterPro:IPR011665"
/db_xref="InterPro:IPR013137"
/db_xref="InterPro:IPR013150"
/db_xref="InterPro:IPR013763"
/db_xref="InterPro:IPR036915"
/db_xref="UniProtKB/Swiss-Prot:Q92994"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAC04512.1"
/translation="MTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKE
VISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPIEEGGQTEAREPPQ
ASSWEGPSTTRRRSQLWHGCPGCGRGGFTLCP"
BASE COUNT 414 a 585 c 654 g 412 t
ORIGIN
1 ggcacgagcg cgcgctgtgc agaggtagcc gtggaaggcg gctcccggcg ctggcaggcg
61 gccgccccca gacccgcagt gccatgcgca ggtgcttgcg cccgttcttc agttagcgat
121 cttttggtta ggaacgcagg tggacctgct tgtttggcca tttgcattcc ggagtctgcc
181 tctggccgcg gcctgtggga tggtcgttgg gcttcctcgt tcgttcagat gcttcgcgat
241 ttagcttgct acggacgcca gcagccagcg cttgcagaga gcgcggtcca ctctgctctg
301 agggctttac aggggcaggc gctgctattt cccggcattt tcctcgagga aataggcaca
361 gagaggttag tcgcgcgctg aaggtcacac agccggcggg tgggcaagtc aggatctggc
421 cctgggcctg cagccctgga gcttgggccc cagggcgcgc cctgcctctg tggctctgcc
481 tgtggatcgc agtcgcaggc tcgctccttg tggggcctct agcctcccgg cctggggcta
541 atcctgggag gtgcgtggca tggggcactg gctttgctga tgaggagacc agacttcaga
601 ggccgtgtca cctggcctgg gccgcacagc tggtgcatgc caagctcgcg tgcagacgaa
661 gctccagagg cctggctgtc aggagggttc ctccccgagg acacacacgc aacctcctgg
721 accgccaggc tttagacttt taaaacttcc atatgcagga aaccccacag gacgcagcca
781 gcatctcggg tcatgggtgc acctgtcacc gcagtcctgg gctaaacagt gaacaggagc
841 tctgtgtctc tgtggtcgtt acagttgtag tgaatgttcc ctgggagagt cctcttcaga
901 agatatttgc ggtattttca acaaaggact ctccaggatg gaggagcaac tacaagtcag
961 gaaggaaaag gctgacaacc cagtttttta aaaaacgggc aaaggacgtg aacagacacc
1021 atgcaatggc ccagagtgca caaatcatca tttctcccag gaatggggtg cccgagcccc
1081 caggcggctg aacttgagac ttgtcaggta gtgttggtgg aatgcagagc agctggagat
1141 cacctgctgc aggtgggtgc gtaactccgc acggccaagc cgtttggaaa gctgtagcat
1201 atgcatgaga gtccggaaag ttccgagaga aagtgtgtgg atgcacccgc caaggacaca
1261 cccaccgagg ccacagctgc gatttcatag tgtgggaccc cactggcaaa gacacgctgg
1321 ctgctgtggc cgtggtttct gtcccagccg tctgtttcca tagaaaaaga cccgtgcctg
1381 tatattccac gctttgcgca cctgctggaa ttcggggaga agaaccacga ggtgtccatg
1441 actgccctga ggctcctaca gaggatgaag cgggactgga tgcacacagg ccggcgcccc
1501 tcgggcctct gcggagcagc gctcctggtt gcagccagaa tgcatgactt caggaggact
1561 gtgaaggagg tcatcagtgt ggtcaaagtg tgtgagtcca cgctgcggaa gaggctcacg
1621 gaatttgaag acacccccac cagtcagttg accattgatg agttcatgaa gatcgacctg
1681 gaggaggagt gcgacccccc catcgaggag ggagggcaga cggaggcccg agagcctccc
1741 caggcctctt cgtgggaagg ccccagtacc actcgtagga ggtctcagct ctggcatggc
1801 tgccccggat gtggccgagg gggcttcacc ctgtgtcctt aggagggggt ggccttgagg
1861 cagagccgtg cctcactgac ccccaggggc ctcatcctcc ccatggaatg ggctgtatgt
1921 cctgccccaa cttggcccgc agcaggccag acccccctac ccccgcccag agctcagtag
1981 ccagcctggg tcctgccagg gcttctcgag ggcttggggg aagaatagat ttagtaaagc
2041 aggaagatct gttgttactt aacag
//