LOCUS AJ290975 2052 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for inositol 1,4,5-trisphosphate 3-kinase C.
ACCESSION AJ290975
VERSION AJ290975.1
KEYWORDS inositol 1,4,5-trisphosphate 3-kinase C; IP3C gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2052)
AUTHORS Dewaste V.
JOURNAL Submitted (08-JUN-2000) to the INSDC. Dewaste V., Interdisciplinary
Research Institute (IRIBHN), Universite Libre de Bruxelles, Campus
Erasme, Bldg C, 808 Route de Lennik, 1070 Brussels, BELGIUM.
REFERENCE 2
AUTHORS Dewaste V., Pouillon V., Moreau C., Shears S., Takazawa K.,
Erneux C.
TITLE Cloning and expression of a cDNA encoding human inositol
1,4,5-trisphosphate 3-kinase C
JOURNAL Biochem. J. 352, 343-351(2000).
PUBMED 11085927
FEATURES Location/Qualifiers
source 1..2052
/db_xref="H-InvDB:HIT000246554"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_type="thyroid"
/db_xref="taxon:9606"
CDS 1..2052
/product="inositol 1,4,5-trisphosphate 3-kinase C"
/function="phosphorylation of I(1,4,5)P3 into
I(1,3,4,5)P4"
/db_xref="GOA:Q96DU7"
/db_xref="H-InvDB:HIT000246554.13"
/db_xref="HGNC:HGNC:14897"
/db_xref="InterPro:IPR005522"
/db_xref="InterPro:IPR038286"
/db_xref="PDB:2A98"
/db_xref="UniProtKB/Swiss-Prot:Q96DU7"
/protein_id="CAC40815.1"
/translation="MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGP
GAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGL
GVETERPKQKTEPDRSSLRTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEE
ASPWTQPGVHGPWTELETHGSQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPS
ADGSWKELYTDGSRTQQDIEGPWTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGS
WTQPSTDGSQTAPGTDCLLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITP
ETPEPEAQPVGPPSRVEGGSGGFSSASSFDESEDDVVAGGGGASDPEDRSGSKPWKKL
KTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLEQLMKDPLR
PFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRK
DMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNT
NFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLF
VHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLAQ
S"
BASE COUNT 455 a 599 c 662 g 336 t
ORIGIN
1 atgaggcgct gcccgtgccg tgggagcctg aacgaggcgg aggccggggc gctgcccgcg
61 gcggcccgca tgggactgga ggcgccgcga ggagggcggc ggcggcagcc gggacagcag
121 cgacctgggc ccggcgcagg ggccccggcg gggcggccgg aggggggcgg gccctgggcc
181 cggacagagg ggtccagcct ccacagcgag cctgagaggg ccggcctcgg gcctgcgccg
241 gggacagaga gtccgcaggc agaattctgg acagacggac agactgagcc cgcggcagct
301 ggccttggag tagagaccga gaggcccaag caaaagacgg agccagacag gtccagcctc
361 cggacgcatc tagaatggag ctggtcagag ctggagacga cttgtctttg gacggagacc
421 gggacagatg gcctttggac tgatccgcac aggtccgacc tccagtttca gcccgaggag
481 gccagcccct ggacacagcc aggggttcat gggccctgga cagagctgga aacgcatggg
541 tcacagactc agccagagag ggtcaagtcc tgggctgata acctctggac ccaccagaac
601 agttccagcc tccagactca cccagaagga gcctgtccct caaaagagcc aagtgctgat
661 ggctcctgga aagaattgta tactgatggc tccaggacac aacaggatat tgaaggtccc
721 tggacagagc catatactga tggctcccag aaaaaacagg atactgaagc agccaggaaa
781 cagcctggca ctggtggttt ccaaatacaa caggatactg atggctcctg gacacaacct
841 agcactgacg gttcccagac agcacctggg acagactgcc tcttgggaga gcctgaggat
901 ggcccattag aggaaccaga gcctggagaa ttgctgactc acctgtactc tcacctgaag
961 tgtagccccc tgtgccctgt gccccgcctc atcattaccc ctgagacccc tgagcctgag
1021 gcccagccag tgggaccccc ctcccgggtt gaggggggca gcggcggctt ctcctctgcc
1081 tcttctttcg acgagtctga ggatgacgtg gtggccgggg gcggaggtgc cagcgatccc
1141 gaggacaggt ctgggagcaa accctggaag aagctgaaga cagttctgaa gtattcaccc
1201 tttgtggtct ccttccgaaa acactaccct tgggtccagc tttctggaca tgctgggaac
1261 ttccaggcag gagaggatgg tcggattctg aaacgtttct gtcagtgtga gcagcgcagc
1321 ctggagcagc tgatgaaaga cccgctgcga cctttcgtgc ctgcctacta tggcatggtg
1381 ctgcaggatg gccagacctt caaccagatg gaagacctcc tggctgactt tgagggcccc
1441 tccattatgg actgcaagat gggcagcagg acctatctgg aagaggagct agtgaaggca
1501 cgggaacgtc cccgtccccg gaaggacatg tatgagaaga tggtggctgt ggaccctggg
1561 gcccctaccc ctgaggagca tgcccagggt gcagtcacca agccccgcta catgcagtgg
1621 agggaaacca tgagctccac ctctaccctg ggcttccgga tcgagggcat caagaaggca
1681 gatgggacct gtaacaccaa cttcaagaag acgcaggcac tggagcaggt gacaaaagtg
1741 ctggaggact tcgtggatgg agaccacgtc atcctgcaaa agtacgtggc atgcctagaa
1801 gaacttcgtg aagctctgga gatctccccc ttcttcaaga cccacgaggt ggtaggcagc
1861 tccctcctct tcgtgcacga ccacaccggc ctggccaagg tctggatgat agacttcggc
1921 aagacggtgg ccttgcccga ccaccagacg ctcagccaca ggctgccctg ggctgagggc
1981 aaccgtgagg acggctacct ctggggcctg gacaacatga tctgcctcct gcaggggctg
2041 gcacagagct ga
//