LOCUS AJ276678 2616 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for HEF like Protein (HEFL gene).
ACCESSION AJ276678
VERSION AJ276678.1
KEYWORDS HEF like Protein; HEFL gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2616)
AUTHORS Duyster J.
JOURNAL Submitted (10-MAR-2000) to the INSDC. Duyster J., Department of
Internal Medicine III, Technical University of Munich,
Ismanningerstr.22, 80636 Munich, GERMANY.
REFERENCE 2
AUTHORS Jahn T., Will T., Bresolin G., Coutinho S., Peschel C., Duyster J.
TITLE HEF-like Protein (HEFL) is involved in Integrin signalling
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..2616
/db_xref="H-InvDB:HIT000246345"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_line="K562"
/db_xref="taxon:9606"
CDS 226..2583
/gene="HEFL"
/product="HEF like Protein"
/function="role in integrin regulation"
/db_xref="GOA:Q9NQ75"
/db_xref="H-InvDB:HIT000246345.13"
/db_xref="HGNC:HGNC:15878"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR014928"
/db_xref="InterPro:IPR021901"
/db_xref="InterPro:IPR035512"
/db_xref="InterPro:IPR035744"
/db_xref="InterPro:IPR036028"
/db_xref="InterPro:IPR037362"
/db_xref="InterPro:IPR038319"
/db_xref="PDB:2CRE"
/db_xref="UniProtKB/Swiss-Prot:Q9NQ75"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAC00655.1"
/translation="MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQH
VPESEGWWKCLLHGRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPT
LPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPR
PVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGV
PLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSS
STFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSNKVPSS
FSDSPSGQQNTKPNIDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSP
EPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKV
VSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEASVREFLDFARGVHGTACNLTD
SNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVAR
MLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKS
TPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERKPRLSEHCRLYFGAL
FKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLC
SLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG"
BASE COUNT 672 a 760 c 642 g 542 t
ORIGIN
1 gaagagtggt gtttttttct tcttcttctt cttttgtggt ttcacatagc aaatgagtga
61 cagtctctac ttacagacaa agtgagacgt caggcattga gacatagctc catagaattc
121 agtttctgag aaccagccag aagcatgcag tgacattgca caatctgcct ctgaagctgg
181 agatactagc tgcagagctc aggggagctg ctccacatca ccgacatgaa gggaacaggc
241 atcatggact gtgcgcccaa ggcactcctg gccagggcac tttatgacaa ctgccctgac
301 tgctctgacg agctggcttt cagcagaggg gacatcctga ccattctgga gcaacacgtg
361 ccagaaagcg agggttggtg gaagtgtttg ctccatggga ggcaaggcct ggcccctgcc
421 aaccgcctcc aaatcctcac ggaggtcgct gcagacaggc cgtgcccccc attcctgaga
481 ggcctggaag aagctcctgc cagctcagag gagacctatc aggtgcccac tctaccccgc
541 cctcccactc caggccccgt ttatgagcag atgaggagtt gggcggaggg gccccagccc
601 cctactgccc aagtctatga attccccgac cctcccacca gtgccagaat catctgtgaa
661 aagactctca gctttccaaa acaggccatc ctcacgcttc ccagacctgt ccgggcctca
721 ctgccgactc tgccttccca ggtgtatgac gtgcctaccc agcaccgggg ccccgtggtc
781 ctgaaggagc cagagaagca gcagttatat gacataccag ccagccccaa gaaggcagga
841 ctccatcccc cagacagcca agcaagtggg cagggtgttc ccctgatatc agtgactacc
901 ttaagaagag gcggttacag cacattacca aatcctcaga aatcggaatg gatttatgac
961 actccagtgt ctccaggaaa ggccagcgtc agaaacacgc ctctcaccag ctttgcggaa
1021 gaatcaaggc cccacgctct ccccagttcc agctccactt tctacaatcc tccaagtggc
1081 agatccaggt ccctcactcc acaactgaat aacaatgtgc ccatgcagaa aaaactcagc
1141 cttccagaaa ttccttctta tggctttctt gtacccagag gcacatttcc tttggatgaa
1201 gatgtcagca acaaggttcc ttcaagcttc tctgattccc cgagtggaca gcagaacacc
1261 aagcccaata tagacatccc taaagcaacg tcgagtgttt ctcaggctgg gaaggagctg
1321 gagaaagcca aggaggtgtc agagaattcc gcgggccata attcctcatg gttctccaga
1381 cggacaactt ccccatctcc tgaaccggac agattatcag gttccagttc tgacagcaga
1441 gctagcatcg tttcctcgtg ctccaccaca tccaccgacg actcctccag ctcttcctcg
1501 gaggagtcag caaaggagct ctccttggac ctggatgtgg ccaaggagac agtgatggct
1561 ctgcagcaca aggtggtcag ctctgtcgct ggcctgatgc tctttgtcag caggaagtgg
1621 agattccgag actatctgga ggccaacatt gatgcaatcc acaggtccac tgatcacata
1681 gaagcctctg taagagaatt tctggatttt gcccgaggag tccatgggac tgcctgtaac
1741 ctcactgaca gtaaccttca gaacagaatt cgggaccaga tgcagaccat ctccaactcc
1801 taccgcatcc tgcttgaaac aaaggaaagc ttggataatc gcaattggcc tctggaagtt
1861 cttgtgactg acagtgtcca gaacagccca gatgaccttg agaggtttgt catggtggca
1921 cggatgcttc cagaagacat caagaggttt gcctccattg tcattgccaa tggaaggctc
1981 ctttttaagc ggaactgtga aaaggaagag actgtgcagt tgaccccaaa tgcagaattt
2041 aagtgtgaaa aatacatcca gcctccccaa agagaaactg aatcacacca aaagagtacc
2101 ccttccacta agcaaaggga agatgaacac tcttctgaac tattaaagaa aaatagagca
2161 aatatctgtg gacagaatcc tggccctctt atacctcagc cttcgagtca acagactcct
2221 gagaggaaac cccgcttatc tgaacactgc cggctgtact ttggggcgct cttcaaagcc
2281 atcagcgcat ttcacggcag cctcagcagc agccagcccg cggagatcat cactcagagc
2341 aagctggtca tcatggtggg acagaagctg gtggacacgc tgtgcatgga gacccaggag
2401 agggacgtgc gcaatgagat cctccgcggc agcagtcacc tctgcagcct gctcaaggac
2461 gtagcgctgg ccactaagaa tgccgtgctc acatacccca gccctgccgc gctggggcac
2521 ctccaggcgg aggctgagaa gctggagcaa cacacgcggc agttcagagg gacactggga
2581 tgaggactgt ctacctccct tcctcctctg ctcacc
//