LOCUS AJ276396 1989 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for matrix extracellular phosphoglycoprotein
(MEPE gene).
ACCESSION AJ276396
VERSION AJ276396.1
KEYWORDS matrix extracellular phosphoglycoprotein; MEPE gene; osteomalacia.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1989)
AUTHORS Rowe P.S.N.
JOURNAL Submitted (06-MAR-2000) to the INSDC. Rowe P.S.N., Biochemistry and
Molecular Biology, Royal Free and University College London Medical
School, Rowland Hill Street, Hampstead, London NW3 2PF, UK.
REFERENCE 2
AUTHORS Rowe P.S.N., De Zoysa P.A., Dong R., Wang H.R., White K.E.,
Econs M.J., Oudet C.L.
TITLE MEPE, a new gene expressed in bone marrow and tumors causing
osteomalacia
JOURNAL Genomics 67(1), 54-68(2000).
PUBMED 10945470
FEATURES Location/Qualifiers
source 1..1989
/db_xref="H-InvDB:HIT000246333"
/organism="Homo sapiens"
/chromosome="4"
/map="4q21.1"
/mol_type="mRNA"
/tissue_type="bone"
/db_xref="taxon:9606"
CDS 50..1627
/gene="MEPE"
/product="matrix extracellular phosphoglycoprotein"
/note="secreted from oncogenic hypophosphataemic tumours"
/db_xref="GOA:Q9NQ76"
/db_xref="H-InvDB:HIT000246333.13"
/db_xref="HGNC:HGNC:13361"
/db_xref="InterPro:IPR009837"
/db_xref="UniProtKB/Swiss-Prot:Q9NQ76"
/protein_id="CAB97250.1"
/translation="MRVFCVGLLLFSVTWAAPTFQPQTEKTKQSCVEEQRQEEKNKDN
IGFHHLGKRINQELSSKENIVQERKKDLSLSEASENKGSSKSQNYFTNRQRLNKEYSI
SNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTA
IKLLGEENKENTPRNVLNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKSKSTHRIQH
NIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFSGDGQPFKDIPGKGEATGPDL
EGKDIQTGFAGPSEAESTHLDTKKPGYNEIPEREENGGNTIGTRDETAKEADAVDVSL
VEGSNDIMGSTNFKELPGREGNRVDAGSQNAHQGKVEFHYPPAPSKEKRKEGSSDAAE
STNYNEIPKNGKGSTRKGVDHSNRNQATLNEKQRFPSKGKSQGLPIPSRGLDNEIKNE
MDSFNGPSHENIITHGRKYHYVPHRQNNSTRNKGMPQGKGSWGRQPHSNRRFSSRRRD
DSSESSDSGSSSESDGD"
sig_peptide 50..100
/gene="MEPE"
mat_peptide 101..1625
/gene="MEPE"
/product="matrix extracellular phosphoglycoprotein"
regulatory 1949..1954
/gene="MEPE"
/inference="non-experimental evidence, no additional
details recorded"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 736 a 360 c 456 g 437 t
ORIGIN
1 cggcacgagc aggtattctg aaggtgaaag ataccagaga ttctcaaaga tgcgagtttt
61 ctgtgtggga ctactccttt tcagtgtgac ctgggcagca ccaacatttc aaccacagac
121 tgagaaaact aagcaaagct gtgtggaaga gcagaggcag gaagaaaaaa acaaagacaa
181 tattggtttt caccatttgg gcaagagaat aaatcaagag ctatcatcta aagaaaatat
241 tgtccaggaa agaaagaaag atttgtccct ttctgaagcc agtgagaata agggaagtag
301 taaatctcaa aattatttca caaatagaca gagactgaat aaagaatata gtatcagtaa
361 caaagagaat actcacaatg gcctgaggat gtcaatttat cctaagtcaa ctgggaataa
421 agggtttgag gatggagatg atgctatcag caaactacat gaccaagaag aatatggcgc
481 agctctcatc agaaataaca tgcaacatat aatggggcca gtgactgcga ttaaactcct
541 gggggaagaa aacaaagaga acacacctag gaatgttcta aacataatcc cagcaagtat
601 gaattatgct aaagcacact cgaaggataa aaagaagcct caaagagatt cccaagccca
661 gaaaagtcca gtaaaaagca aaagcaccca tcgtattcaa cacaacattg actacctaaa
721 acatctctca aaagtcaaaa aaatccccag tgattttgaa ggcagcggtt atacagatct
781 tcaagagaga ggggacaatg atatatctcc tttcagtggg gacggccaac cttttaagga
841 cattcctggt aaaggagaag ctactggtcc tgacctagaa ggcaaagata ttcaaacagg
901 gtttgcaggc ccaagtgaag ctgagagtac tcatcttgac acaaaaaagc caggttataa
961 tgagatccca gagagagaag aaaatggtgg aaataccatt ggaactaggg atgaaactgc
1021 gaaagaggca gatgctgttg atgtcagcct tgtagagggc agcaacgata tcatgggtag
1081 taccaatttt aaggagctcc ctggaagaga aggaaacaga gtggatgctg gcagccaaaa
1141 tgctcaccaa gggaaggttg agtttcatta ccctcctgca ccctcaaaag agaaaagaaa
1201 agaaggcagt agtgatgcag ctgaaagtac caactataat gaaattccta aaaatggcaa
1261 aggcagtacc agaaagggtg tagatcattc taataggaac caagcaacct taaatgaaaa
1321 acaaaggttt cctagtaagg gcaaaagtca gggcctgccc attccttctc gtggtcttga
1381 taatgaaatc aaaaacgaaa tggattcctt taatggcccc agtcatgaga atataataac
1441 acatggcaga aaatatcatt atgtacccca cagacaaaat aattctacac ggaataaggg
1501 tatgccacaa gggaaaggct cctggggtag acaaccccat tccaacagga ggtttagttc
1561 ccgtagaagg gatgacagta gtgagtcatc tgacagtggc agttcaagtg agagcgatgg
1621 tgactagtcc accaggagtt cccagcgggg tgacagtctg aagacctcgt cacctgtgag
1681 ttgatgtaga ggagagccac ctgacagctg accaggtgaa gagaggatag agtgaagaac
1741 tgagtgagcc aagaatcctg gtctccttgg gggaattttt gctatcttaa tagtcacagt
1801 ataaaattct attaaaggct ataatgtttt taagcaaaaa aaaatcatta cagatctatg
1861 aaataggtaa catttgagta ggtgtcattt aaaaatagtt ggtgaatgtc acaaatgcct
1921 tctatgttgt ttgctctgta gacatgaaaa taaacaatat ctctcgatga taaaaaaaaa
1981 aaaaaaaaa
//