LOCUS AJ275986 2078 bp mRNA linear HUM 21-OCT-2008
DEFINITION Homo sapiens mRNA for transcription factor (SMIF gene).
ACCESSION AJ275986
VERSION AJ275986.1
KEYWORDS SMIF gene; transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2078)
AUTHORS Duyster J.
JOURNAL Submitted (06-MAR-2000) to the INSDC. Duyster J., Department of
Internal Medicine III, Technical University of Munich,
Ismanningerstr.22, 80636 Munich, GERMANY.
REFERENCE 2
AUTHORS Bai R.Y., Koester C., Ouyang T., Hahn S.A., Hammerschmidt M.,
Peschel C., Duyster J.
TITLE SMIF, a Smad4-interacting protein that functions as a co-activator
in TGFbeta signalling
JOURNAL Nat. Cell Biol. 4(3), 181-190(2002).
PUBMED 11836524
FEATURES Location/Qualifiers
source 1..2078
/db_xref="H-InvDB:HIT000246272"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_lib="clontech library"
/tissue_type="pancreas"
/db_xref="taxon:9606"
CDS 94..1842
/gene="SMIF"
/product="transcription factor"
/function="role for SMAD4-mediated transcription"
/db_xref="GOA:Q9NPI6"
/db_xref="H-InvDB:HIT000246272.14"
/db_xref="HGNC:HGNC:18714"
/db_xref="InterPro:IPR010334"
/db_xref="InterPro:IPR011993"
/db_xref="InterPro:IPR031953"
/db_xref="PDB:2WX3"
/db_xref="PDB:4B6H"
/db_xref="UniProtKB/Swiss-Prot:Q9NPI6"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB77023.1"
/translation="MEALSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQ
WEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASL
SIYSIWFYDKNDCHRIAKLMADVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEM
LSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLT
VEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGV
PSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPS
LPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSV
DLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASA
SLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIPVAGAPLVTATTTAVSSVLLAPSVFQ
QTVTRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQLQDTLIHLIKNDSSFLSTLH
EVYLQVLTKNKDNHNL"
BASE COUNT 587 a 576 c 472 g 443 t
ORIGIN
1 ggggactgac gcagatgggg gaattttgcc tcgatggcac tttcctgtcc gcgactccgc
61 ccccaccaga ggggctaggc tctgggattc aagatggagg cgctgagtcg agctgggcag
121 gagatgagcc tagcggccct gaagcaacac gacccctata tcaccagcat cgcagacctc
181 acgggccagg tcgctctgta caccttctgc cccaaggcca accagtggga gaagactgat
241 atagaaggga ccttattcgt atatcgaagg tcagcttccc cttaccatgg ttttaccatt
301 gtgaatcgac taaatatgca caatctagtt gaaccagtga ataaagattt ggaatttcag
361 ctccatgaac catttcttct gtatagaaat gcaagcttgt cgatatatag tatctggttt
421 tatgacaaga atgactgtca ccgcatagca aaactcatgg ctgatgtggt agaagaggag
481 acacggcgat cccagcaagc tgctcgggac aaacagagtc ccagccaggc caatggctgc
541 agcgaccaca ggcccatcga catcctggag atgctgagca gagccaagga tgagtatgag
601 aggaatcaga tgggtgactc aaatatctcc agccctgggt tacagccaag cactcagctc
661 tccaatctgg gaagcaccga gactctagaa gaaatgccct ccgggtcaca ggataagtct
721 gctccatctg gacacaagca tctgacggta gaagagttat ttggaacctc tttgccaaag
781 gaacaaccag cagttgtggg tctggattca gaagaaatgg agaggttgcc aggagatgcc
841 tcccagaaag agcccaattc attcctacca tttccctttg agcagttagg aggagcccct
901 caatcagaaa ccctgggtgt cccttctgct gcccaccatt cagtccagcc tgaaatcacc
961 accccggtgc taatcactcc agcctccatc acacagtcca atgaaaagca tgctccaacc
1021 tacacaatcc cgttgagccc tgttctcagt cccactctgc cagctgaagc tcctactgca
1081 caggttcccc ccagcttacc tcgaaacagc accatgatgc aggcagtgaa gaccacgcct
1141 agacagaggt ctccactcct gaaccagcca gtccctgagc taagccatgc cagtctgatt
1201 gccaaccaga gccccttcag ggccccattg aacgtgacga acacagctgg cacatccctc
1261 ccaagcgttg atcttctcca gaaactcagg ttgaccccac agcatgacca aatacagaca
1321 caaccacttg ggaaaggtgc aatggtagcc agcttttctc cggcagctgg tcagctagcc
1381 acacctgaga gcttcataga gcctccctct aagacagcag cagcaagagt ggcggcctca
1441 gcctccctga gcaacatggt gcttgctccc cttcagtcta tgcagcagaa ccaggatcct
1501 gaagtatttg tgcagcctaa ggtgttatcc agtgccatcc cggttgcagg cgccccactg
1561 gttactgcaa cgaccactgc agtgtcttca gtcctgctgg ccccaagtgt tttccagcag
1621 acagttacaa gatcttcgga ccttgagagg aaagccagct ccccttctcc tctaactatt
1681 ggaacgccag aaagtcagag aaagccttcc attattctca gcaagtctca gctccaggat
1741 acattaatac atctaataaa gaatgattcc agcttcctca gtacacttca tgaagtctac
1801 ttgcaggtgc tgaccaagaa caaagacaac cacaacctat gactggagca gaataagtct
1861 aaaggcagag ccccagcctc agagacaaat aggcttcatc atggaaactt ctgagcagaa
1921 cattgagttt gagaatcctg aaattgagcc tatgagaaag agactcattt cttaagaatg
1981 ttttccaagt gacattctca gtgataatgg aggtttcact gtgaagcatc accagcagat
2041 ccttgttttg acaaaaaaaa aaaaaaaaaa aaaaaaaa
//