LOCUS AJ251506 2646 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for organic anion transporter 8 (SLC21A8 gene).
ACCESSION AJ251506
VERSION AJ251506.1
KEYWORDS OATP8; organic anion transporter; SLC21A8 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2646)
AUTHORS Konig J.
JOURNAL Submitted (07-DEC-1999) to the INSDC. Konig J., Tumor Biochemistry,
Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120
Heidelberg, GERMANY.
REFERENCE 2
AUTHORS Konig J., Cui Y., Nies A.T., Keppler D.
TITLE Localization and genomic organization of a new hepatocellular
organic anion transporting polypeptide
JOURNAL J Biol Chem 275(30), 23161-23168(2000).
PUBMED 10779507
FEATURES Location/Qualifiers
source 1..2646
/db_xref="H-InvDB:HIT000246008"
/organism="Homo sapiens"
/chromosome="12"
/map="12p12"
/mol_type="mRNA"
/tissue_type="liver"
/db_xref="taxon:9606"
5'UTR <1..44
/gene="SLC21A8"
CDS 45..2153
/gene="SLC21A8"
/product="organic anion transporter 8 (OATP8)"
/db_xref="GOA:Q9NPD5"
/db_xref="H-InvDB:HIT000246008.15"
/db_xref="HGNC:HGNC:10961"
/db_xref="InterPro:IPR002350"
/db_xref="InterPro:IPR004156"
/db_xref="InterPro:IPR020846"
/db_xref="InterPro:IPR036058"
/db_xref="InterPro:IPR036259"
/db_xref="UniProtKB/Swiss-Prot:Q9NPD5"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB96997.1"
/translation="MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALG
GIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCL
LMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEK
DCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMI
GPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPF
FFLPKNPNKPQKERKISLSLHVLKTNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILT
NPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFL
GGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVAS
HVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTVFYNCSCVE
VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPE
LKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRV
YLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASDNERKVMDEANLEFLNNGEHFVP
SAGTDSKTCNLDMQDNAAAN"
3'UTR 2154..2646
/gene="SLC21A8"
BASE COUNT 869 a 424 c 495 g 858 t
ORIGIN
1 atcagcaaca attaaaatat tcacgtggta tctgtagttt aataatggac caacatcaac
61 atttgaataa aacagcagag tcagcatctt cagagaaaaa gaaaacaaga cgctgcaatg
121 gattcaagat gttcttggca gccctgtcat tcagctatat tgctaaagca ctaggtggaa
181 tcattatgaa aatttccatc actcaaatag aaaggagatt tgacatatcc tcttctcttg
241 ctggtttaat tgatggaagc tttgaaattg gaaatttgct tgtgattgta tttgtaagtt
301 actttggatc taaactacac agaccgaagt taattggaat tggttgtctc cttatgggaa
361 ctggaagtat tttgacatct ttaccacatt tcttcatggg atattatagg tattctaaag
421 aaacccatat taatccatca gaaaattcaa catcaagttt atcaacctgt ttaattaatc
481 aaaccttatc attcaatgga acatcacctg agatagtaga aaaagattgt gtaaaggaat
541 ctgggtcaca catgtggatc tatgtcttca tggggaatat gcttcgtggc ataggggaaa
601 cccccatagt accattgggg atttcataca ttgatgattt tgcaaaagaa ggacattctt
661 ccttgtattt aggtagtttg aatgcaatag gaatgattgg tccagtcatt ggctttgcac
721 tgggatctct gtttgctaaa atgtacgtgg atattggata tgtagatctg agcactatca
781 gaataactcc taaggactct cgttgggttg gagcttggtg gcttggtttc cttgtgtctg
841 gactattttc cattatttct tccataccat tttttttctt gccgaaaaat ccaaataaac
901 cacaaaaaga aagaaaaatt tcactatcat tgcatgtgct gaaaacaaat gatgatagaa
961 atcaaacagc taatttgacc aaccaaggaa aaaatgttac caaaaatgtg actggttttt
1021 tccagtcttt gaaaagcatc cttaccaatc ccctgtatgt tatatttctg cttttgacat
1081 tgttacaagt aagcagcttt attggttctt ttacttacgt ctttaaatat atggagcaac
1141 agtacggtca gtctgcatct catgctaact ttttgttggg aatcataacc attcctacgg
1201 ttgcaactgg aatgttttta ggaggattta tcattaaaaa attcaaattg tctttagttg
1261 gaattgccaa attttcattt cttacttcga tgatatcctt cttgtttcaa cttctatatt
1321 tccctctaat ctgcgaaagc aaatcagttg ccggcctaac cttgacctat gatggaaata
1381 attcagtggc atctcatgta gatgtaccac tttcttattg caactcagag tgcaattgtg
1441 atgaaagtca gtgggaacca gtctgtggga acaatggaat aacttacctg tcaccttgtc
1501 tagcaggatg caaatcctca agtggtatta aaaagcatac agtgttttat aactgtagtt
1561 gtgtggaagt aactggtctc cagaacagaa attactcagc acacttgggt gaatgcccaa
1621 gagataatac ttgtacaagg aaatttttca tctatgttgc aattcaagtc ataaactctt
1681 tgttctctgc aacaggaggt accacattta tcttgttgac tgtgaagatt gttcaacctg
1741 aattgaaagc acttgcaatg ggtttccagt caatggttat aagaacacta ggaggaattc
1801 tagctccaat atattttggg gctctgattg ataaaacatg tatgaagtgg tccaccaaca
1861 gctgtggagc acaaggagct tgtaggatat ataattccgt attttttgga agggtctact
1921 tgggcttatc tatagcttta agattcccag cacttgtttt atatattgtt ttcatttttg
1981 ctatgaagaa aaaatttcaa ggaaaagata ccaaggcatc ggacaatgaa agaaaagtaa
2041 tggatgaagc aaacttagaa ttcttaaata atggtgaaca ttttgtacct tctgctggaa
2101 cagatagtaa aacatgtaat ttggacatgc aagacaatgc tgctgccaac taacattgca
2161 ttgattcatt aagatgttat ttttgaggtg ttcctggtct ttcactgaca attccaacat
2221 tctttactta cagtggacca atggataagt ctatgcatct ataataaact ataaaaaatg
2281 ggagtaccca tggttaggat atagctatgc ctttatggtt aagattagaa tatatgatcc
2341 ataaaattta aagtgagagg catggttagt gtgtgataca ataaaaagta attgtttggt
2401 agttgtaact gctaataaaa ccagtgacta gaatataagg gaggtaaaaa ggacaagata
2461 gattaatagc ctaaataaag agaaaagcct gatgccttta aaaaatgaaa cactttggat
2521 gtattactta ggccaaaatc tggcctggat ttatgctata atatatattt tcatgttaag
2581 ttgtatattt ttcagaaatt ataaatatta ttaatttaaa attcgaaaaa aaaaaaaaaa
2641 aaaaaa
//