LOCUS AJ251016 3095 bp mRNA linear HUM 21-OCT-2008
DEFINITION Homo sapiens mRNA for calcium-activated potassium channel SK3 (K3
(KCNN3) gene).
ACCESSION AJ251016
VERSION AJ251016.1
KEYWORDS calcium-activated potassium channel; K3 (KCNN3) gene; SK3 protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3095)
AUTHORS Chen M.X.
JOURNAL Submitted (15-NOV-1999) to the INSDC. Chen M.X., Molecular
Pharmacology, GlaxoWellcome Medicines Research Center, Gunnels Wood
Road, Stevenage, Herts, SG1 2NY, UNITED KINGDOM.
REFERENCE 2
AUTHORS Terstappen G.C., Pula G., Carignani C., Chen M.X., Roncarati R.
TITLE Pharmacological characterisation of the human small conductance
calcium-activated potassium channel hSK3 reveals sensitivity to
tricyclic antidepressants and antipsychotic phenothiazines
JOURNAL Neuropharmacology 40(6), 772-783(2001).
PUBMED 11369031
FEATURES Location/Qualifiers
source 1..3095
/db_xref="H-InvDB:HIT000245984"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_lib="nontumorous prostate"
/db_xref="taxon:9606"
CDS 334..2544
/gene="K3 (KCNN3)"
/product="SK3 protein"
/function="Small-conductance calcium-activated potassium
channel"
/db_xref="GOA:Q9UGI6"
/db_xref="H-InvDB:HIT000245984.14"
/db_xref="HGNC:HGNC:6292"
/db_xref="InterPro:IPR004178"
/db_xref="InterPro:IPR013099"
/db_xref="InterPro:IPR015449"
/db_xref="InterPro:IPR036122"
/db_xref="UniProtKB/Swiss-Prot:Q9UGI6"
/protein_id="CAB61331.1"
/translation="MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPP
PAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVH
PGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRH
RQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQLFSP
SNPPEIVISSREDNHAHQTLLHHPNATHNHQHAGTTASSTTFPKANKRKNQNIGYKLG
HRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTII
LLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWT
ARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINF
NTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISI
TFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMD
TQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQR
KLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLI
ADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSSSSC"
BASE COUNT 729 a 970 c 790 g 606 t
ORIGIN
1 gggtcgaccc acgcgtccgg agccagcgag gagtgaagct gagcctggcc tcacacgctc
61 ctagaggacc acctcctgag agagttcttt caccccctct tctttctcca agctcccctc
121 ctgctctccc tccctgccca atacaatgca ttcttgagtg gcagcgtctg gactccaggc
181 agccccagag aaccgaagca agccaaagag aggactggag ccaagatact ggtgggggag
241 attggatgcc tggctttctt tgaggacatc tttggagcga gggtggcttt ggggtggggg
301 cttgtgctgc agggaataca gccaggcccc aagatggaca cttctgggca cttccatgac
361 tcgggggtgg gggacttgga tgaagacccc aagtgcccct gtccatcctc tggggatgag
421 cagcagcagc agcagcagca gcaacagcag cagcagccac caccgccagc gccaccagca
481 gccccccagc agcccctggg accctcgctg cagcctcagc ctccgcagct tcagcagcag
541 cagcagcagc agcagcagca gcagcagcag cagcagcagc agcagcagcc accgcatccc
601 ctgtctcagc tcgcccaact ccagagccag cccgtccacc ctggcctgct gcactcctct
661 cccaccgctt tcagggcccc cccttcgtcc aactccaccg ccatcctcca cccttcctcc
721 aggcaaggca gccagctcaa tctcaatgac cacttgcttg gccactctcc aagttccaca
781 gctacaagtg ggcctggcgg aggcagccgg caccgacagg ccagccccct ggtgcaccgg
841 cgggacagca accccttcac ggagatcgcc atgagctcct gcaagtatag cggtggggtc
901 atgaagcccc tcagccgcct cagcgcctcc cggaggaacc tcatcgaggc cgagactgag
961 ggccaacccc tccagctttt cagccctagc aaccccccgg agatcgtcat ctcctcccgg
1021 gaggacaacc atgcccacca gaccctgctc catcacccta atgccaccca caaccaccag
1081 catgccggca ccaccgccag cagcaccacc ttccccaaag ccaacaagcg gaaaaaccaa
1141 aacattggct ataagctggg acacaggagg gccctgtttg aaaagagaaa gcgactgagt
1201 gactatgctc tgatttttgg gatgtttgga attgttgtta tggtgataga gaccgagctc
1261 tcttggggtt tgtactcaaa ggactccatg ttttcgttgg ccctgaaatg ccttatcagt
1321 ctgtccacca tcatcctttt gggcttgatc atcgcctacc acacacgtga agtccagctc
1381 ttcgtgatcg acaacggcgc ggatgactgg cggatagcca tgacctacga gcgcatcctg
1441 tacatcagcc tggagatgct ggtgtgcgcc atccacccca ttcctggcga gtacaagttc
1501 ttctggacgg cacgcctggc cttctcctac acaccctccc gggcggaggc cgatgtggac
1561 atcatcctgt ctatccccat gttcctgcgc ctgtacctga tcgcccgagt catgctgctg
1621 cacagcaagc tcttcaccga tgcctcgtcc cgcagcatcg gggccctcaa caagatcaac
1681 ttcaacaccc gctttgtcat gaagacgctc atgaccatct gccctggcac tgtgctgctc
1741 gtgttcagca tctctctgtg gatcattgct gcctggaccg tccgtgtctg tgaaaggtac
1801 catgaccagc aggacgtaac tagtaacttt ctgggtgcca tgtggctcat ctccatcaca
1861 ttcctttcca ttggttatgg ggacatggtg ccccacacat actgtgggaa aggtgtctgt
1921 ctcctcactg gcatcatggg tgcaggctgc actgcccttg tggtggccgt ggtggcccga
1981 aagctggaac tcaccaaagc ggagaagcac gttcataact tcatgatgga cactcagctc
2041 accaagcgga tcaagaatgc tgcagccaat gtccttcggg aaacatggtt aatctataaa
2101 cacacaaagc tgctaaagaa gattgaccat gccaaagtga ggaaacacca gaggaagttc
2161 ctccaagcta tccaccagtt gaggagcgtc aagatggaac agaggaagct gagtgaccaa
2221 gccaacactc tggtggacct ttccaagatg cagaatgtca tgtatgactt aatcacagaa
2281 ctcaatgacc ggagcgaaga cctggagaag cagattggca gcctggagtc gaagctggag
2341 catctcaccg ccagcttcaa ctccctgccg ctgctcatcg ccgacaccct gcgccagcag
2401 cagcagcagc tcctgtctgc catcatcgag gcccggggtg tcagcgtggc agtgggcacc
2461 acccacaccc caatctccga tagccccatt ggggtcagct ccacctcctt cccgaccccg
2521 tacacaagtt caagcagttg ctaaataaat ctccccactc cagaagcatt acccataggt
2581 cttaagatgc aaatcaactc tctcctggtc gctttgccat caagaaacat tcagaccagg
2641 gaacggaaag aagagagacc gagctaatta actaactcat gttcattcag cgtgcttggt
2701 ccgacatgcc ttgaaaccag aaatctaatc tctgtttagg tgcctctact tgggagcggg
2761 aagaggagat gacaggaagc gacgcctctg gcagggccct tgctgcagag ttggtggaga
2821 acagaaatcc acgctcaatc tcaggtcttc acgcgggggg tgggggtcag atgcactgaa
2881 gtagccaaca gcgaaaccag tccagaagag gggtccgctg ggagggaggg ttgtgtcagg
2941 cttgggggat gggctcttcg ccatgggggt ctttgaacac acctctctcc tttccttttg
3001 tctacggaag cctctgggtg acaaaagtaa aagagagctg cccacaactt gccaaaacag
3061 atatactcga atcagactga aaaaaaaaaa aaaaa
//