LOCUS AJ249341 2385 bp mRNA linear ROD 23-SEP-2008
DEFINITION Mus musculus mRNA for mitochondrial thymidine kinase 2 (TK2 gene).
ACCESSION AJ249341
VERSION AJ249341.2
KEYWORDS mitochondrial thymidine kinase 2; TK2 gene.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1
AUTHORS Wang L.
JOURNAL Submitted (03-SEP-1999) to the INSDC. Wang L., Veterinary Medical
Chemistry, The Swedish University of Agricultural Sciences, The
Biomedical Center, Box 575, Uppsala, SE-751 23, SWEDEN.
REMARK revised by [3]
REFERENCE 2
AUTHORS Wang L., Eriksson S.
TITLE Cloning and characterisation of full length mouse thymidine kinase
2: the N -terminal sequence directs import of the precursor protein
into mitochondria
JOURNAL Biochem. J. 351, 469-476(2000).
PUBMED 11023833
REFERENCE 3 (bases 1 to 2385)
AUTHORS Wang L.
JOURNAL Submitted (05-OCT-2000) to the INSDC. Wang L., Veterinary Medical
Chemistry, The Swedish University of Agricultural Sciences, The
Biomedical Center, Box 575, Uppsala, SE-751 23, SWEDEN.
FEATURES Location/Qualifiers
source 1..2385
/organism="Mus musculus"
/lab_host="top10"
/strain="c57bl"
/mol_type="mRNA"
/sex="female"
/dev_stage="adult"
/clone_lib="sugano mouse brain mncb"
/tissue_type="brain"
/db_xref="taxon:10090"
CDS 4..816
/gene="TK2"
/product="mitochondrial thymidine kinase 2"
/function="phosphorylate pyrimidine nucleosides to their
5' monophosphate"
/EC_number="2.7.1.21"
/db_xref="GOA:Q9R088"
/db_xref="InterPro:IPR002624"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR031314"
/db_xref="MGI:MGI:1913266"
/db_xref="UniProtKB/Swiss-Prot:Q9R088"
/protein_id="CAC07190.2"
/translation="MLLRSLRSWAARSPRSVGPGSSGSPGSLDSGAGPLWAPRRAWPP
DKDRENDKEKKAVVCIEGNIASGKTTCLEFFSNTTDVEVLMEPVLKWRNVHGHNPLSL
MYHDASRWGLTLQTYVQLTMLDQHTRPQMSPVRLMERSIYSARYIFVENLYRGGKMPE
VDYAILSEWFDWIVRNIDVSVDLIVYLRTTPEICYQRLKMRCREEEKVIPMEYLHAIH
RLYEEWLVNGSLFPAAAPVLVIEADHNLEKMLELFEQNRARILTPENWKHGP"
polyA_site 2352
BASE COUNT 568 a 592 c 645 g 580 t
ORIGIN
1 actatgctgc tgcggtcgct gcgtagttgg gctgcccggt ccccgcgtag cgtgggcccg
61 gggagctccg ggagccccgg gagcctcgat tcgggcgccg ggccgctgtg ggcacctcgc
121 cgcgcctggc ctccggataa agatagagaa aatgataagg agaaaaaagc agtggtttgt
181 attgagggca atattgcaag tgggaagacg acatgcctgg agttcttctc caatacaaca
241 gacgtcgagg tgttaatgga gcctgtgctc aagtggagaa atgtccatgg ccataaccct
301 ctgagcctca tgtaccatga tgccagccga tggggcctca cactgcagac gtacgtgcag
361 ctcaccatgc tggaccagca cacgcgccct cagatgtcac ctgtacggtt gatggaaagg
421 tcaatttaca gcgcaagata catttttgta gaaaacctgt atagaggtgg gaagatgccc
481 gaggttgact acgcgattct gtctgagtgg tttgactgga tcgtcaggaa cattgatgtc
541 tctgttgatc tgatagttta tctgcgaacc actcccgaaa tctgctacca gagattaaag
601 atgaggtgcc gggaagagga gaaagtcatt ccgatggaat acctccatgc tattcaccgc
661 ctctacgagg agtggctggt caacgggagc ctcttcccag ctgcagcccc tgttctggtg
721 attgaggctg accacaactt ggagaaaatg ttagaactct ttgaacaaaa ccgggcccgg
781 atattaactc cagagaactg gaagcatgga ccctaggact gagtgatcta caagacagcg
841 ccaggaacag cccagccagg gccaggttag ctgctaggag catttggaag aatctactct
901 taggagggtc tgttatctaa tcagatctat tttctcaatg gtctttttca ctgcagtaca
961 aatggctttt gtctgtcaga tgcttgcagc atacatccct cctggtgccc ctcctggtgg
1021 cttcctaacg atgaagccct gtgttaaaat cactgactgt atccctgggg ttgttctgga
1081 tcctctgcat caggtcacct catgggtgag gggagcagtc ttcaccccag gcaaggattt
1141 gaagcccaga gaggtgtggg gactcgtcaa gccagacatt gtggagggag ctgggaccat
1201 tcaggtacct ggtttgggct gcctcctcct aagctgttcc ccaccgccct gctgctctga
1261 gcaccagccc ccgcctctgt gagaagagtg gacagtttgt gaattccatc atctttcagt
1321 accgggccag ttcaaggaga ccagacatca ctaggtgttg gcacacctct cttatttggc
1381 atgagcccag ggtgtcctgg tatgagggta ctgtgacctc tatccattcc tttgtcacct
1441 ggacctcggt gtccactggg gactcctgga tcggcctctg cttggtgcca gagtccttga
1501 ggatgagtcc tccccagact ctacccgttc cctgtcgttt tgtgtcagaa aaaagggggt
1561 tatgggacct ggacacttta ccctttgctg agcgaggcca agggcagcca gctgagcttc
1621 caagacccca tcactctctc ctgtccttgt gtgagagagc agtgtcccct tgctccaggg
1681 agagtgacag tggccttaac tcctttgaag tgtttttcca tctgagcaga tgtcatgacc
1741 cacgagcatg aagaagtcat ctctattgga tcagaaaata ccttagcttt gctgagccgt
1801 aactgtgcac tgaaggtgca gcttgttact tgaatcagtc atgaccaaga gaggccggcc
1861 attcctcagg accgtgagac tggaaagtca tggtttgcca acaaagacaa tttaagcctt
1921 gctgctcttg acattctaga atggatggag tgcatctgga aaagactgga cacagatgat
1981 acaggggaat gatgaccgta taccctggag aagcacagca caggctgggg agggggctgc
2041 aggggagccc tgctcccctg tttagctgcc tgggagctag aaagagggcc aagagtccag
2101 ctcttggtcc tttctgtttg gaccaattct tggccctttt ggtagtatga agagtagcat
2161 ccagggagat tgtccatcag cacctgcagt ccagcaatgg ataaacctga gaaaggcagg
2221 aactttgaac cagcagtact catgggggca tctttagaat ttgcaaacga acagtctagt
2281 acttgccctt tgctctacca gaacacttgt tttggggaga aatgtgctgt ttctctttct
2341 ctctagtagc caataaaatt ctacagctaa aaaaaaaaaa aaaaa
//