LOCUS AJ247087 2760 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for myosin light chain kinase (MLCK).
ACCESSION AJ247087
VERSION AJ247087.1
KEYWORDS MLCK; myosin light chain kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2760)
AUTHORS Gautel M.S.
JOURNAL Submitted (22-JUN-1999) to the INSDC. Gautel M.S., Physikalische
Biochemie, Max-Planck-Institut fuer molekulare Physiologie,
Otto-Hahn-Strasse 11, Dortmund, 44227, GERMANY.
REFERENCE 2
AUTHORS Mues A., Seidel R., Gautel M.
TITLE The cardiac-MyBP-C associated Ca/CaM kinase is a novel MLCK with
cardiac-specific domains
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..2760
/db_xref="H-InvDB:HIT000245912"
/organism="Homo sapiens"
/mol_type="mRNA"
/dev_stage="adult"
/cell_type="cardiomyocytes"
/tissue_type="heart"
/db_xref="taxon:9606"
CDS 189..2576
/product="myosin light chain kinase (MLCK)"
/function="protein ser:thr kinase"
/db_xref="GOA:Q32MK0"
/db_xref="H-InvDB:HIT000245912.14"
/db_xref="HGNC:HGNC:29826"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="UniProtKB/Swiss-Prot:Q32MK0"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAC42766.1"
/translation="MDTKLNMLNEKVDQLLHFQEDVTEKLQSMCRDMGHLERGLHRLE
ASRAPGPGGADGVPHIDTQAGWPEVLELVRAMQQDAAQHGARLEALFRMVAAVDRAIA
LVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEEEGGKPKHVLSTSGLQSDA
REPGEESQKADVLERTAERLPPIRASGLGADPAQAVVSPGQGDGVPGPAQAFPGHLPL
PTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEE
GTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGP
TLTTEAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEE
EQRAGAEPGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVR
RMPPGAEAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRC
TEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVME
YVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQT
GHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLL
SGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQC
LKHEWLNNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP"
BASE COUNT 662 a 745 c 860 g 493 t
ORIGIN
1 aggagtctgt cagctacgga ggacaatgac cttgcagaca ccaccgcctg agtgagaacc
61 aggggtctgt gcctctcctc attccccgct cttgcccttg tcaagcctgc accagcatgt
121 caggaacctc caaggagagt ctggggcatg gggggctgcc agggttgggc aagacctgct
181 taacaaccat ggacacaaag ctgaacatgc tgaacgagaa ggtggaccag ctcctgcact
241 tccaagaaga tgtcacagag aagttgcaga gcatgtgccg agacatgggc cacctggagc
301 ggggcctgca caggctggag gcctcccggg caccgggccc gggcggggct gatggggttc
361 cccacattga cacccaggct gggtggcccg aggtcctgga gctggtgagg gccatgcagc
421 aggatgcggc ccagcacggt gccaggctgg aggccctctt caggatggtg gctgcggtgg
481 acagggccat cgctttggtg ggggccacgt tccagaaatc aaaggtggcg gatttcctca
541 tgcaggggcg tgtgccctgg aggagaggca gcccaggtga cagccctgag gagaataaag
601 agcgagtgga agaagaggga ggaaaaccaa agcatgtgct gagcaccagt gggttgcagt
661 ctgatgccag ggagcctggg gaagagagcc agaaggcgga cgtgctggaa aggacagcgg
721 agaggctgcc ccccatcaga gcgtcagggc tgggagctga ccccgcccag gcagtggtct
781 caccgggcca gggagatggt gttcctggcc cagcccaggc attccctggc cacctgcccc
841 tgcccacaaa ggtggaagcc aaggctcctg agacacccag cgagaacctc aggactggcc
901 tggaattggc tccagcaccc ggcagggtca atgtggtctc cccgagcctg gaggttgcac
961 caggtgcagg acaaggagca tcgtccagca ggcctgaccc tgagccctta gaggaaggca
1021 cgaggctgac tccagggcct ggccctcagt gcccagggcc tccagggctg ccagcccagg
1081 ccagggcaac ccacagtggt ggagaaacac ctccaaggat ctccatccac atacaagaga
1141 tggatactcc tggggagatg ctgatgacag gcaggggcag ccttggaccc accctcacca
1201 cagaggctcc agcagctgcc cagccaggca agcagggccc acctgggacc gggcgctgcc
1261 tccaagcccc tgggactgag cccggagaac agacccctga aggagccaga gagctctccc
1321 cgctgcagga gagcagcagc cccgggggag tgaaggcaga ggaggagcaa agggctgggg
1381 ccgagcctgg cacgagacca agcttggcca ggagtgacga caatgaccac gaggttgggg
1441 ccctgggcct gcagcagggc aaaagcccag gggcgggaaa ccctgagcct gagcaggact
1501 gtgcagccag ggctccggtg agagctgaag cagtaaggag gatgccccca ggcgccgagg
1561 ctggcagcgt ggttctggat gacagtccgg ccccaccagc tccttttgaa caccgggtag
1621 tgagcgtcaa ggagacctcc atctctgcgg gttacgaggt gtgccagcac gaagtcttgg
1681 gagggggtcg gtttggccag gtccacaggt gcacagagaa gtccacaggc ctcccactgg
1741 ctgccaagat catcaaagtg aagagcgcca aggaccggga ggacgtgaag aacgagatca
1801 acatcatgaa ccagctcagc cacgtgaacc tgatccagct ctatgacgcc ttcgagagca
1861 agcacagctg cacccttgtc atggagtacg tggacggggg tgagctcttc gaccggatca
1921 cagatgagaa gtaccacctg actgagctgg atgtggtcct gttcaccagg cagatctgtg
1981 agggtgtgca ttacctgcac cagcactaca tcctgcacct ggacctcaag ccggagaaca
2041 tattgtgcgt caatcagaca ggacatcaaa ttaagatcat tgactttggg ctggccagaa
2101 ggtacaagcc tcgagagaag ctgaaggtga acttcggcac tcctgagttc ctggccccag
2161 aagtcgtcaa ttatgagttt gtctcattcc ccacagacat gtggagtgtg ggagtcatca
2221 cctacatgct actcagtggc ttgtccccat ttctagggga aacagatgca gagaccatga
2281 atttcattgt aaactgtagc tgggattttg atgctgacac ctttgaaggg ctctcggagg
2341 aggccaagga ctttgtttcc cggttgctgg tcaaagagaa gagctgcaga atgagtgcca
2401 cacagtgcct gaaacacgag tggctgaata atttgcctgc caaagcttca agatccaaaa
2461 ctcgtctcaa atcccaacta ctgctgcaga aatacatagc tcaaagaaaa tggaagaaac
2521 atttctatgt ggtgactgct gccaacaggt taaggaaatt tccaacttct ccctaatctt
2581 caactctgct gctccaatgg gtccagaaat tactgaggcc agtggtgaag tgaagagatg
2641 actcaaacat ttaaataatt tggcttttgg tattattgat tccacttatt tgtaaatggt
2701 tatggctgct gcttcctgtg gatgaaagtg gctgtaagag ctcctagacg tttctgctgt
//