LOCUS AJ243797 1239 bp mRNA linear HUM 15-APR-2005
DEFINITION Homo sapiens mRNA for deoxyribonuclease III (drn3 gene).
ACCESSION AJ243797
VERSION AJ243797.1
KEYWORDS deoxyribonuclease III; DNase III; drn3 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1239)
AUTHORS Lindahl T.
JOURNAL Submitted (13-JUL-1999) to the INSDC. Lindahl T., Clare Hall
Laboratories, Imperial Cancer Research Fund, South Mimms,
Hertfordshire, EN6 3LD, UNITED KINGDOM.
REFERENCE 2
AUTHORS Hoss M., Robins P., Naven T.J., Pappin D.J., Sgouros J., Lindahl T.
TITLE A human DNA editing enzyme homologous to the Escherichia coli
DnaQ/MutD protein
JOURNAL EMBO J. 18(13), 3868-3875(1999).
PUBMED 10393201
FEATURES Location/Qualifiers
source 1..1239
/db_xref="H-InvDB:HIT000245551"
/organism="Homo sapiens"
/chromosome="3"
/map="3p21.2-21.3"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 257..1171
/gene="drn3"
/product="deoxyribonuclease III (DNase III)"
/function="3' exonuclease"
/db_xref="GOA:Q9NSU2"
/db_xref="H-InvDB:HIT000245551.13"
/db_xref="HGNC:HGNC:12269"
/db_xref="InterPro:IPR012337"
/db_xref="InterPro:IPR013520"
/db_xref="InterPro:IPR036397"
/db_xref="UniProtKB/Swiss-Prot:Q9NSU2"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB50866.1"
/translation="MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPP
PTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFL
RRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSE
HGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGT
IRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLRESRGTKDLPPVKDPGALSREG
LLAPLGLLAILTLAVATLYGLSLATPGE"
BASE COUNT 249 a 401 c 368 g 221 t
ORIGIN
1 gaattcggca cgaggtgaaa ggccgcagca ggggctccca gcagtgtgta agaccgggag
61 ctggtctggc accactgccc tggtccttcc agctgcctgt cactggtatg atggccccgg
121 tgcattgtgc caccagcagg ccacagctgt ggatcttgga aggcctctgg ggtcccccgg
181 gagcagggga gtgggtgtgg gggggaacgg atggtggtga gacggacaga ccaggcaggc
241 cctgcccccg gggcccatgc agaccctcat ctttttcgac atggaggcca ctggcttgcc
301 cttctcccag cccaaggtca cggagctgtg cctgctggct gtccacagat gtgccctgga
361 gagccccccc acctctcagg ggccacctcc cacagttcct ccaccaccgc gtgtggtaga
421 caagctctcc ctgtgtgtgg ctccggggaa ggcctgcagc cctgcagcca gcgagatcac
481 aggtctgagc acagctgtgc tggcagcgca tgggcgtcaa tgttttgatg acaacctggc
541 caacctgctc ctagccttcc tgcggcgcca gccacagccc tggtgcctgg tggcacacaa
601 tggtgaccgc tacgacttcc ccctgctcca agcagagctg gctatgctgg gcctcaccag
661 tgctctggat ggtgccttct gtgtggatag catcactgcg ctgaaggccc tggagcgagc
721 aagcagcccc tcagaacacg gcccaaggaa gagctatagc ctaggcagca tctacactcg
781 cctgtatggg cagtcccctc cagactcgca cacggctgag ggtgatgtcc tggccctgct
841 cagcatctgt cagtggagac cacaggccct gctgcggtgg gtggatgctc acgccaggcc
901 tttcggcacc atcaggccca tgtatggggt cacagcctct gctaggacca agccaagacc
961 atctgctgtc acaaccactg cacacctggc cacaaccagg aacactagtc ccagccttcg
1021 agagagcagg ggtaccaagg atcttcctcc agtgaaggac cctggagccc tatccaggga
1081 ggggctgctg gccccactgg gtctgctggc catcctgacc ttggcagtag ccacactgta
1141 tggactatcc ctggccacac ctggcgagta ggccaagaag gaaaatctga cgaataaaga
1201 cccccgctgc cccaaaaaaa aaaaaaaaat tgcggccgc
//