LOCUS AJ242987 3208 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for breast cancer anti-estrogen resistance 1
protein (BCAR1 gene).
ACCESSION AJ242987
VERSION AJ242987.2
KEYWORDS BCAR1 gene; BCAR1 protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Dorssers L.C.J.
JOURNAL Submitted (04-JUN-1999) to the INSDC. Dorssers L.C.J., Dept. of
Pathology, Division of Molecular Biology, Josephine Nefkens
Institute, University Hospital Rotterdam, P.O. Box 1738, 3000 DR
Rotterdam, NETHERLANDS.
REMARK Revised by [3]
REFERENCE 2
AUTHORS Brinkman A., Van der Flier S., Kok E.M., Dorssers L.C.J.
TITLE BCAR1, a human homologue of the adapter protein p130Cas, and
antiestrogen resistance in breast cancer cells
JOURNAL J. Natl. Cancer Inst. 92(2), 112-120(2000).
PUBMED 10639512
REFERENCE 3 (bases 1 to 3208)
AUTHORS Dorssers L.C.J.
JOURNAL Submitted (28-FEB-2000) to the INSDC. Dorssers L.C.J., Dept. of
Pathology, Division of Molecular Biology, Josephine Nefkens
Institute, University Hospital Rotterdam, P.O. Box 1738, 3000 DR
Rotterdam, NETHERLANDS.
FEATURES Location/Qualifiers
source 1..3208
/db_xref="H-InvDB:HIT000245499"
/organism="Homo sapiens"
/chromosome="16"
/map="q23.1"
/mol_type="mRNA"
/cell_line="ZR-75-1"
/tissue_type="breast"
/db_xref="taxon:9606"
CDS 122..2734
/gene="BCAR1"
/product="breast cancer anti-estrogen resistance 1
protein"
/db_xref="GOA:P56945"
/db_xref="H-InvDB:HIT000245499.14"
/db_xref="HGNC:HGNC:971"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR014928"
/db_xref="InterPro:IPR021901"
/db_xref="InterPro:IPR028848"
/db_xref="InterPro:IPR035745"
/db_xref="InterPro:IPR036028"
/db_xref="InterPro:IPR037362"
/db_xref="InterPro:IPR038319"
/db_xref="PDB:1WYX"
/db_xref="PDB:3T6G"
/db_xref="PDB:5O2M"
/db_xref="PDB:5O2P"
/db_xref="PDB:5O2Q"
/db_xref="UniProtKB/Swiss-Prot:P56945"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB75875.2"
/translation="MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWW
LCSLHGRQGIVPGNRLKILVGMYDKKPAGPGSGPPATPAQPQPGLHAPAPPASQYTPM
LPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSP
ATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRV
GQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG
PNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFA
KAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRE
RVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPG
REPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAV
AAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGR
GGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLHPN
PTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKEL
LEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSD
RQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDT
LSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHS
TQQFRRVLGQLAAA"
regulatory 3189..3194
/gene="BCAR1"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 578 a 1105 c 1017 g 508 t
ORIGIN
1 gaggcggcag ctgcgcggcg gcaccggggc ggctgcggcg cgctcggagc cccgaggcac
61 gcggcccggg cagctcggtg tgcgcccccg cgagagccgg gccccaggcc cgccggacac
121 catgaaccac ctgaacgtgc tggccaaagc gctctatgac aatgtggccg agtccccgga
181 tgagctctcc ttccgcaagg gtgacatcat gacggtgctg gagcaggaca cgcagggcct
241 ggacggctgg tggctctgct cgctgcatgg gcgccagggc atcgtgcctg ggaaccgcct
301 caagatcttg gtgggcatgt atgataagaa gccagcaggg cctggctccg gccctcccgc
361 caccccggcc cagcctcagc ctggcctcca tgccccagcg cctccggcct cccagtacac
421 gcccatgctc cccaacacct accagcccca gccagacagc gtctacctgg tgcccactcc
481 cagcaaggct cagcaaggcc tctaccaagt cccgggtccc agccctcagt tccagtctcc
541 cccagccaag cagacatcca ccttctcgaa gcagacaccc catcacccgt ttcccagccc
601 ggccacagac ctgtaccagg tgcccccagg gcctggaggc cctgcccagg atatttacca
661 ggtgccacct tctgccggga tggggcatga catctaccag gtccccccgt ccatggacac
721 acgcagctgg gagggcacga agcccccggc aaaggtggtg gtgcccaccc gcgtggggca
781 gggctatgta tacgaggccg cccagccgga gcaggacgag tacgacatcc cgcgacacct
841 gctggccccg gggccacagg acatctatga tgtgcccccg gttcgggggc tgcttcccag
901 ccagtatggc caggaggtgt atgacacacc ccccatggct gtcaagggtc ccaatggccg
961 agacccgttg ctggaggtgt atgacgtgcc ccccagtgtg gagaagggcc tgccaccgtc
1021 caaccaccac gcagtctacg acgttcctcc atcggtgagc aaggatgtgc ccgatggccc
1081 actgctgcgt gaggagacct acgatgtgcc ccccgccttc gccaaggcca agccctttga
1141 cccggcccgc accccactgg tactggctgc gccccctcca gactccccgc cggccgagga
1201 cgtgtatgac gtgccgcccc cggctcctga cctctacgac gtgccccctg gcttgcggcg
1261 gcctggcccg ggcaccctgt acgatgtgcc ccgtgaacgg gtgcttcctc ctgaggtggc
1321 tgatggtggc gtggtcgaca gtggtgtgta tgcggtgcct cccccagctg aacgtgaagc
1381 cccggcagag ggcaagcgcc tgtcggcctc cagcaccggc agcacacgca gcagccagtc
1441 tgcgtcctcc ttggaggtgg cagggccggg ccgggaaccc ctggagctgg aagttgctgt
1501 ggaggccctg gcacggctgc agcagggtgt gagcgccacc gttgcccacc ttctggacct
1561 ggcaggcagc gccggtgcga ctgggagctg gcgtagcccc tctgagccac aggagccgct
1621 ggtgcaggac ctgcaggctg ctgtggccgc tgtccagagt gccgtccacg agctgttgga
1681 gtttgcccgc agcgcggtgg gcaatgctgc ccacacatct gaccgtgccc tgcatgccaa
1741 gcttagccgg cagctgcaga agatggagga cgtgcaccag acgctggtgg cacatggtca
1801 ggccctcgac gctggccggg gaggctctgg agccaccctt gaggacctgg accggctggt
1861 ggcctgctcg cgggctgtgc ccgaggacgc caagcagctg gcctccttcc tgcacggcaa
1921 tgcctcactg ctcttcagac ggaccaaggc cactgccccg gggcctgagg ggggtggcac
1981 cctgcacccc aaccccactg acaagaccag cagcatccag tcacgacccc tgccctcacc
2041 ccctaagttc acctcccagg actcaccaga tgggcagtac gagaacagcg aggggggctg
2101 gatggaggac tatgactacg tccacctaca ggggaaggag gagtttgaga agacccagaa
2161 ggagctgctg gaaaagggca gcatcacgcg gcagggcaag agccagctgg agttgcagca
2221 gctgaagcag tttgaacgac tggaacagga ggtgtcacgg cccatagacc acgacctggc
2281 caactggacg ccagcccaac ccctggcccc ggggcgaaca ggcggcctgg ggccctcgga
2341 ccggcagctg ctgctcttct acctggagca gtgtgaggcc aacctgacca cactgaccaa
2401 cgccgtggac gccttcttta ccgccgtggc caccaaccag ccgcccaaga tctttgtggc
2461 gcacagcaag ttcgtcatcc tcagcgccca caagctggtg ttcatcgggg acacactgtc
2521 acggcaggcc aaggctgctg acgtgcgcag ccaggtgacc cactacagca acctgctgtg
2581 cgacctcctg cgcggcatcg tggccaccac caaggccgct gccttgcagt acccatcgcc
2641 ttccgcggcc caggacatgg tggagagggt caaggagctg ggccacagca cccagcagtt
2701 ccgccgcgtc ctaggccagc tggcagccgc ctgagggtgg tgaccccagg agggaggcag
2761 gggaggggtg cggcggtccc agctccctgg ctcccatgtc aagagtcgct gtgccacagg
2821 cttagggaca ggaccccagc tctgcgtcgg tcctggtgcc ctggatgccc aggaatctgt
2881 atatatttat ggccgggcag ggtgtggggc catgcctcct caggagccga agcccagggg
2941 ccgcagtggc cttccccagc atgcaccacg ggcccgggtt gggtcaccag acggggctgg
3001 agtgtgaggg tcctgcagcc tgcaggacct cgtgccaccc cgagggctga gcctggtccc
3061 acgagggtgc cgtgtcccct gacagggcca gtgcagtttg gtgtgtcctc cgccttacca
3121 ggagaagaac ctgaagaact atttttcgtt attggttttc caatcatttg actaagagtc
3181 tccatttaaa taaagttttt aaaaggaa
//