LOCUS AJ242780 5883 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for inositol 1,4,5-trisphosphate 3-kinase isoform
B.
ACCESSION AJ242780
VERSION AJ242780.1
KEYWORDS inositol 1,4,5-trisphosphate 3-kinase; IP3K-B gene; isoform b.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5883)
AUTHORS Bertsch U.
JOURNAL Submitted (31-MAY-1999) to the INSDC. Bertsch U., Institut fuer
Physiologische Chemie, Universitaets-Krankenhaus Eppendorf,
Martinistrasse 52, Hamburg, D-20246, GERMANY.
REFERENCE 2
AUTHORS Bertsch U., Suesse S., Frerk S., Fanick W.
TITLE Cloning of the complete protein coding regions for inositol
1,4,5-trisphosphate 3-kinase B-isoforms form rat and human
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..5883
/db_xref="H-InvDB:HIT000245485"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_type="colon"
/db_xref="taxon:9606"
5'UTR 1..57
/gene="IP3K-B"
CDS 58..2898
/gene="IP3K-B"
/product="inositol 1,4,5-trisphosphate 3-kinase, isoform
B"
/function="phosphotransferase"
/EC_number="2.7.1.127"
/db_xref="GOA:P27987"
/db_xref="H-InvDB:HIT000245485.15"
/db_xref="HGNC:HGNC:6179"
/db_xref="InterPro:IPR005522"
/db_xref="InterPro:IPR038286"
/db_xref="UniProtKB/Swiss-Prot:P27987"
/protein_id="CAC40650.1"
/translation="MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSP
GSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSW
AGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSA
IQAPRSPRLGRAHSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCSETSGTDSG
RKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEID
KRGSPTPGTRSCLAPSLGLFAPSFPMATEVAARVTSTGPHRPQDLALTEPSGRARELE
DLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKR
PEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTL
GLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRV
WQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDQDKPFLRKACSPSNI
PAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPE
RTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKA
AANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPC
VMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQ
WRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRD
RLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDV
PWQEGNREDGYLSGLNNLVDILTEMSQDAPLA"
BASE COUNT 1263 a 1638 c 1755 g 1227 t
ORIGIN
1 ggcataggcg caggctgaat agtagcagcg gcggcgggca gcgcgggacc cagtactatg
61 gctgtgtact gctatgcgct caatagcctg gtgatcatga atagcgccaa cgagatgaag
121 agcggcggcg gcccggggcc cagtggcagc gagacgcccc cgcccccgag gagggcagtg
181 ctgagccccg gcagcgtttt cagccccggg agaggcgcct ctttcctctt ccccccagcc
241 gagtcgctgt cccccgagga gccccggagc cccgggggct ggcggagcgg ccggcgcagg
301 ctgaatagta gcagcggcag tggcagcggc agcagcggca gtagcgtgag cagcccaagt
361 tgggctggtc gcctgcgagg ggaccggcag caggtggtgg cagccggtac cctctccccg
421 ccagggccgg aggaggccaa gaggaagctg cggatcttgc agcgcgagtt gcagaacgtg
481 caggtgaacc agaaagtggg catgtttgag gcgcacatcc aggcacagag ctccgccatt
541 caagcgcccc gcagcccgcg tttgggcagg gctcactcgc cctccccgtg ccccttccgc
601 agcagcagtc agccccctgg aagggtcctg gttcagggcg cccggagcga ggaacggagg
661 acaaagtcct ggggggagca atgttcagag acttcaggaa ccgactccgg gaggaaagga
721 gggcccagcc tatgctcctc gcaggtgaag aaaggaatgc cacctcttcc cggccgggct
781 gcccctacag gatcagaggc tcagggtcca tccgcttttg taaggatgga gaagggtatc
841 cctgccagtc cccgctgtgg ctcacccaca gctatggaaa ttgacaaaag gggctctcct
901 accccgggaa ctcggagctg cctagctccc tcattggggc tgttcgcccc tagcttcccg
961 atggccacgg aagtggcagc gagagttaca tccactgggc cacaccgtcc acaggatctt
1021 gccctcactg agccgtctgg gagagcccgt gagcttgagg acctgcagcc cccagaggcc
1081 ctggtggaga ggcaggggca gtttctgggc agtgagacaa gcccagcccc agaaaggggc
1141 gggccccgcg atggagaacc ccctgggaag atggggaaag gatatctgcc ctgtggcatg
1201 ccgggctctg gggagcctga agtgggcaaa aggccagagg agacgactgt gagcgtgcaa
1261 agcgcagagt cctctgattc cctgagctgg tccaggctgc ccagggccct ggcctccgta
1321 ggccctgagg aggcccgaag tggggccccc gtgggcgggg ggcgttggca gctctccgac
1381 agagtggagg gagggtcccc aacgctgggc ttgcttgggg gcagcccctc agcacagccg
1441 gggaccggga atgtggaggc gggaattcct tctggcagaa tgctggagcc tttgccctgt
1501 tgggacgctg cgaaagatct gaaagaacct cagtgccctc ctggggacag ggtgggtgtg
1561 cagcctggga actccagggt ttggcagggc accatggaga aagccggttt ggcttggacg
1621 cgtggcacag gggtgcaatc agaggggact tgggaaagcc agcggcagga cagtgatgcc
1681 ctcccaagtc cggagctgct accccaagat caggacaagc ctttcctgag gaaggcctgc
1741 agccccagca acatacctgc tgtcatcatt acagacatgg gcacccagga ggatggggcc
1801 ttggaggaga cgcagggaag ccctcggggc aacctgcccc tgaggaaact gtcctcttcc
1861 tcggcctcct ccacgggctt ctcctcatcc tacgaagact cagaggagga catctccagt
1921 gaccctgagc gcaccctgga ccccaactca gctttcctgc ataccctgga ccagcagaaa
1981 cctagagtga gcaaatcatg gaggaagata aaaaacatgg tgcactggtc tcccttcgtc
2041 atgtccttca agaagaagta cccctggatc cagctggcag gacacgcagg gagtttcaag
2101 gcagctgcca atggcaggat cctgaagaag cactgtgagt cagagcagcg ctgcctggac
2161 cggctgatgg tggatgtgct gaggcccttc gtacctgcct accatgggga tgtggtgaag
2221 gacggggagc gctacaacca gatggacgac ctgctggccg acttcgactc gccctgtgtg
2281 atggactgca agatgggaat caggacctac ctggaggagg agctcacgaa ggcccggaag
2341 aagcccagcc tgcggaagga catgtaccag aagatgatcg aggtggaccc cgaggccccc
2401 accgaggagg aaaaagcaca gcgggctgtg accaagccac ggtacatgca gtggcgggag
2461 accatcagct ccacggccac cctggggttc aggatcgagg gaatcaagaa agaagacggc
2521 accgtgaacc gggacttcaa gaagaccaaa acgagggagc aggtcaccga ggccttcaga
2581 gagttcacta aaggaaacca taacatcctg atcgcctatc gggaccggct gaaggccatt
2641 cgaaccactc tagaagtttc tcccttcttc aagtgccacg aggtcattgg cagctccctc
2701 ctcttcatcc acgacaagaa ggaacaggcc aaagtgtgga tgatcgactt tgggaaaacc
2761 acgcccctgc ctgagggcca gaccctgcag catgacgtcc cctggcagga ggggaaccgg
2821 gaggatggct acctctcggg gctcaataac ctcgtcgaca tcctgaccga gatgtcccag
2881 gatgccccac tcgcctgagc tgcccacgcc ctccctggcc cccgcctggg cctcctttcc
2941 tcctcctgtg cttcctttct cgttcctaac ttttccttca cttacacctg actgaccctc
3001 ctgaactgca ctacaagaca ctttgtagaa gaggagatga gagtttctag tcattttcct
3061 aacttcaggg cttggaggtg gtgtttgcac tgctttttgt agagagggtc acctactaga
3121 agagaaatgc ccagtcttag aggtgggtca ggtgtagagc tggagggggt ccctggctgc
3181 tgaggggacc ctaccagatg agccctgcct ctgggagccc cctaggaagc accagcctgg
3241 acctaccacc tgcggaggcc tgctgccccc tggcggccag tgctgttaga gtgctgccaa
3301 gcacagcctt atttctgccg gggcctcccc accggagagc ccagggggcc ggccgggttc
3361 ctggtccctg gctgggagca gggctttctg gtagttgggg cacaaaacca tcggggaacc
3421 acatgttgac tgtgagcaaa gtgtcttccg attagcagcc tcagggatgc cctggtggcc
3481 tctccagggc tgctcaggca aggcccccca cccatctggt atggaaacct gccggctcca
3541 ggccagaccc aggagccaag agaaggctga agccagcttg gctgtgttct ctgatctagg
3601 ccttcccaga ggaggcgagc agaagctgtg ccacttggaa ttgcaaccca tgagttcaga
3661 aggcacactc tgccatgctg agctccaagg gtgctaccag gggaagatgg gatctataga
3721 gtctctgggc cctggcccca gggaggagca catttttctt gaccctcacc tacctggtgc
3781 tagttggtca accctgcctg catacatggg ctcctgtcat ggggcccaga gtcccttgca
3841 gatatagaaa taggggagga gctcaggtct gcgccaggca ggaagaaggc aggcttctgg
3901 cttccagagg tgccgcggtg gcctcctggc atcatttgtt attgcctctg aaacaagcct
3961 tactgcctgg agggcttaga ttcctgcttc cccaatgtag tgtgggtatc ttgtagggta
4021 tgtggtggat gccagggcgt gctccaggca cctcttcctg aagtctctgc atttggagat
4081 tcgtggagaa cctatttaag cccaatttta actgaaagcc agtgagtctg atatggaagg
4141 gaatgtaaaa tttgcctgac ttcttaagaa caaaaccccc agctctgtgc cccatgctcc
4201 ttggggcttg ccacccactc ctttgctgtc agaggtacag gagctgggag agtccaggag
4261 ctagggacac agagggagac tatggaccaa ggtgtgtgtg tctggaggaa ccactgccca
4321 ccccaccacc ccggggtctc tggggaactg tcaacctgcc cacgggacat gtacatttcc
4381 ccttttgtgc tggaagtgtg agtgacactt gctgggggtg gagggtggga cacatgagga
4441 tgtataagta cagattttaa aaaaggaaat caacttacac ttcctggctc ttgtttaaaa
4501 cagtggtgag ctcctgtgtg ggccgacttg ctaaaggtca cacacgcgcc cggtggagca
4561 cgagagacct cgtggcagca tgtgatctgg aaggcaggca ggacgggggc gttggggagc
4621 caaagtcaac tctgggcctc tggagctata gtgacttttg ggctagaagg gaccctggtg
4681 gtctgtgctt cagccatttg cagggcaggg gcatcattaa ttcagacgta aagattctat
4741 gaatatggac tggccaaaag ttatccttac tccatctgtg aaagaagttt gctaaagcaa
4801 atcatgatat gaacaaaaat tacaggggac ctgtttaaga gaacaaaatg ttccaagcac
4861 tttaggcaga caccagctgt ttgcaaacaa tgtgctaata tgcaaatgat gtgcttatta
4921 aaggaggccc atggggcctc ttattggcaa tacttggctg tgggttacat taaatatgtg
4981 aacatagtat gaagtagcat cattttaggg ttattctgtt acttagggtt tttgttttct
5041 gttttttttt tctctttttt tgtatttacc gtgctagttc tcttctacac ctactctgtc
5101 tctcaagcca ttttgccact cgcttccctg ccatctggcc cttccctttg tctcagtggg
5161 atagatggat tgtgaaatgg aatctcccag aacccctgcc ctggcagcct ggaagaccgt
5221 gcctgcccag ccctcgtcac cacagggact ccttgggtcc tggcagtgca tgtgccagca
5281 ggcaggacaa actctgtgta cctgtgccca ggtgaatggg cgcagggtcc tcttgccctg
5341 tcctgcgggg ggccccacga gttcctggca ttcagcactg cttagcattc tcggaaggtt
5401 tcttcaactg cttgcttttc ccaggcttgc ctttagtgtc atgtaagaca tttttaagtt
5461 atatttattt tgttgggttt taaaattgca cagaacacta agaccgaaag gctggactct
5521 tgtttctcct tgaaagcttt gcctttgttt tgaacttcct ttcccacttg gtagaaagag
5581 cccagaagca gccctggccc tgtaagatgg actctttcat ccttcagttg tatttagctt
5641 tgagtttctc tgcatctgtc caccccatgt gtatataacc cagcccctgg ctctggggtg
5701 gtcacctcgt cagtgccttt tgttctggag gagaggaccc ccccgcctgc cgagaggctc
5761 tcttcctgtt ctgcacccct ctccccatgg gaccttggag aaaactgaac tgttacaaac
5821 ccctgcacag tgcctgtcaa acagatgcaa accttcctga ataaagcctt ggagacggaa
5881 ttc
//