LOCUS AJ238403 7020 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for huntingtin interacting protein 1.
ACCESSION AJ238403
VERSION AJ238403.1
KEYWORDS HIF-1 gene; huntingtin interacting protein 1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7020)
AUTHORS Rega S.
JOURNAL Submitted (21-APR-1999) to the INSDC. Rega S., Institute of
Molecular Biology, University of Essen, Hufelandstr.55, 45122
Essen, GERMANY.
REFERENCE 2
AUTHORS Rega S., Stiewe T., Chang D.I., Pollmieier B., Esche H.,
Bardenheuer W., Marquitam G., Puetzer B.M.
TITLE Identification of the full-length huntingtin- interacting protein
p231HBP/HYPB as a DNA-binding factor
JOURNAL Mol. Cell. Neurosci. 18(1), 68-79(2001).
PUBMED 11461154
FEATURES Location/Qualifiers
source 1..7020
/db_xref="H-InvDB:HIT000245251"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 410..6595
/gene="HIF-1"
/product="huntingtin interacting protein 1"
/db_xref="GOA:Q9BYW2"
/db_xref="H-InvDB:HIT000245251.13"
/db_xref="HGNC:HGNC:18420"
/db_xref="InterPro:IPR001202"
/db_xref="InterPro:IPR001214"
/db_xref="InterPro:IPR003616"
/db_xref="InterPro:IPR006560"
/db_xref="InterPro:IPR013257"
/db_xref="InterPro:IPR035441"
/db_xref="InterPro:IPR036020"
/db_xref="InterPro:IPR038190"
/db_xref="InterPro:IPR042294"
/db_xref="PDB:2A7O"
/db_xref="PDB:2MDC"
/db_xref="PDB:2MDI"
/db_xref="PDB:2MDJ"
/db_xref="PDB:4FMU"
/db_xref="PDB:4H12"
/db_xref="PDB:5JJY"
/db_xref="PDB:5JLB"
/db_xref="PDB:5JLE"
/db_xref="PDB:5LSS"
/db_xref="PDB:5LSX"
/db_xref="PDB:5LSY"
/db_xref="PDB:5LSZ"
/db_xref="PDB:5LT6"
/db_xref="PDB:5LT7"
/db_xref="PDB:5LT8"
/db_xref="PDB:5V21"
/db_xref="PDB:5V22"
/db_xref="UniProtKB/Swiss-Prot:Q9BYW2"
/protein_id="CAC28349.1"
/translation="MERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSK
HDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINK
NPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQL
RSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGF
QNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPV
DTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICD
SRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSL
TLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNG
LSGKCLQEAQKEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMED
SDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV
VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQ
TDKFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPN
SEETVKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEI
PHVDGLHSSEELRNLGWDFSQEKPSATYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQ
GNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLS
LQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSES
DGELQDRKKVRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDL
IEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRC
PNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKA
RVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVG
FFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKE
RSRKKDSVDGELEALMENGEGLSDKNQVPSLSRLMVRIETLEQKLTCLELIQNTHSQS
CLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPI
IQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRL
KIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVD
SETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQE
QPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPK
TPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDR
NKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGY
PMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHV
AAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYS
PAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVV
VQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEG
KIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEAD
TSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNK
ELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE"
BASE COUNT 2307 a 1430 c 1587 g 1696 t
ORIGIN
1 acgatctaaa acagacagag atgataaata ttttagctat tcaaaacttg aatgagatac
61 tcggtatgta tcttcccgat gtagatcaga aagagagcga cggcggagca gatctcactc
121 taggtctgag agaggctcta gaactaattt atcctattcc agatcagaac gatctcatta
181 ttatgactct gatcgtcgct accataggag ctccccttat cgagagagga cgcgctattc
241 tcggccatac acagataaca gagcacgaga gagttctgac tcagaagaag agtataagaa
301 gacatactca aggcgtacct catctcattc ctcttcttac agggacctaa ggacatcatc
361 ctattctaaa tctgatcggg actgtaaaac tgagacctct tacttagaga tggaaagaag
421 aggcaagtat tcttcaaaac tagaaagaga atctaaaagg acttcagaaa atgaagcaat
481 taaaagatgt tgttctcccc ctaatgaact gggattccga cgagggtcat catattctaa
541 gcatgacagt agtgcttccc gttataaatc taccctttca aaacctatac ccaagtctga
601 taaatttaaa aattctttct gttgtacaga attaaatgaa gaaatcaaac aatctcattc
661 ttttagttta cagacacctt gttcaaaagg tagtgaatta agaatgatta ataaaaatcc
721 tgaaagagaa aaggctgggt ctccagctcc atcaaatcga ttaaatgatt cacctacttt
781 aaaaaagcta gatgaattgc ctatttttaa gtccgaattt ataacacatg atagccatga
841 tagtattaag gaattagact ctttatctaa agtgaagaat gatcaattaa gaagtttttg
901 tcccatagaa ttaaatataa atggatctcc tggggcagaa tctgatttgg caacattttg
961 cacttctaaa actgatgctg ttttaatgac ttctgatgat agtgtgactg gatcggaatt
1021 atcccctttg gtcaaagcat gcatgctttc atcaaatgga tttcagaata ttagtaggtg
1081 caaagaaaaa gacttggatg atacctgcat gctgcataag aagtcagaaa gcccatttag
1141 agaaacagaa cctctggtgt caccacacca agataaactc atgtctatgc cagttatgac
1201 tgtggattat tccaaaacag tagttaaaga accagttgat acgagggttt cttgctgcaa
1261 aaccaaagat tcagacatat actgtacttt gaacgatagc aacccttctt tgtgtaactc
1321 tgaagctgaa aatattgagc cttcagttat gaagatttct tcaaatagct ttatgaatgt
1381 gcatttggaa tcaaaaccag ttatatgtga tagtagaaat ttgacagatc actcaaaatt
1441 tgcatgtgaa gaatataagc agagcatcgg tagcactagt tcagcttctg ttaatcattt
1501 tgatgattta tatcaaccta ttgggagttc aggtattgct tcatctcttc agagtcttcc
1561 accaggaata aaggtggaca gtctaactct cttgaaatgc ggagagaaca catctccagt
1621 tctggatgca gtgctaaaga gtaaaaaaag ttcagagttt ttaaagcatg cagggaaaga
1681 aacaatagta gaagtaggta gtgaccttcc tgattcagga aagggatttg cttccaggga
1741 gaacaggcgt aataatgggt tatctgggaa atgtttgcaa gaggctcaaa aagaagggaa
1801 ttccatattg cctgaaagaa gaggaagacc agaaatctct ttagatgaaa gaggagaagg
1861 aggacatgtg catacttctg atgactcaga agttgtattt tcttcttgtg atttgaattt
1921 aaccatggaa gacagtgatg gtgtaactta tgcattaaag tgtgacagta gtggtcatgc
1981 cccagaaatt gtgtctacag ttcatgaaga ttattctggc tcttctgaaa gttcaaatga
2041 tgaaagtgat tcagaagata cggattcgga tgatagcagt attccaagaa accgtctcca
2101 gtctgttgtg gttgtgccaa agaattctac tttgcccatg gaagaaacaa gtccttgttc
2161 ttctcggagc agtcaaagtt atagacacta ttctgaccat tgggaagatg agagattgga
2221 gtcaaggaga catttgtatg aggaaaaatt tgaaagtata gcaagtaaag cctgtcctca
2281 aactgataag tttttccttc ataaaggaac agagaagaat ccggaaattt cttttacaca
2341 gtccagtaga aaacaaatag ataaccgcct gcctgaactt tctcatcctc agagtgatgg
2401 ggttgatagt acaagtcata cagatgtgaa atctgaccct ctgggtcacc caaattcaga
2461 ggaaaccgtg aaagccaaaa taccttctag gcagcaagaa gagctgccaa tttattcttc
2521 tgattttgaa gatgtcccaa ataagtcttg gcaacagacc actttccaaa acaggccaga
2581 tagtagactg ggaaaaacag aattgagttt ttcttcctct tgtgagatac cacatgtgga
2641 tggcttgcac tcatcagaag agctcagaaa cttaggttgg gacttctctc aagaaaagcc
2701 ttctgccacg tatcagcaac ctgacagtag ctatggagct tgtggtggac acaagtatca
2761 gcaaaatgca gaacagtatg gtgggacacg tgattactgg caaggcaatg gttactggga
2821 tccaagatca ggtagacctc ctggaactgg ggttgtgtat gatcgaactc aaggacaagt
2881 accagattcc ctaacagatg atcgtgaaga agaggagaat tgggatcaac aggatggatc
2941 ccatttttca gaccagtccg ataaatttct tctatccctt cagaaagaca aggggtcagt
3001 gcaagcacct gaaataagca gcaattccat taaggacact ttagctgtga atgaaaagaa
3061 agatttttca aaaaacttag aaaaaaatga tatcaaagat agagggcctc ttaaaaaaag
3121 gaggcaggaa atagagagtg attctgaaag tgatggtgag cttcaggaca gaaagaaagt
3181 tagagtggag gtagagcagg gagagacatc agtgccccca ggttcagcac tggttgggcc
3241 ctcctgtgtc atggatgact tcagggaccc acagcgatgg aaggaatgtg ccaagcaagg
3301 gaaaatgcca tgttactttg atcttattga agaaaatgtt tatttaacag aaagaaagaa
3361 gaataaatct catcgagata ttaagcgaat gcagtgtgag tgtacacctc tttctaaaga
3421 tgaaagagct caaggtgaaa tagcatgtgg ggaagattgt cttaatcgtc ttctcatgat
3481 tgaatgttct tctcggtgtc caaatgggga ttattgttcc aatagacggt ttcagagaaa
3541 acagcatgca gatgtggaag tcatactcac agaaaagaaa ggctggggct tgagagctgc
3601 caaagacctt ccttcgaaca cctttgtcct agaatattgt ggagaggtac tcgatcataa
3661 agagtttaaa gctcgagtga aggagtatgc acgaaacaaa aacatccatt actatttcat
3721 ggccctgaag aatgatgaga taatagatgc cactcaaaaa ggaaattgct ctcgtttcat
3781 gaatcacagc tgtgaaccaa attgtgaaac ccaaaaatgg actgtgaacg gacaactgag
3841 ggttgggttt tttaccacca aactggttcc ttcaggctca gagttaacgt ttgactatca
3901 gttccagaga tatggaaaag aagcccagaa atgtttctgc ggatcagcca attgccgggg
3961 ttacctggga ggagaaaaca gagtcagcat tagagcagca ggagggaaaa tgaagaagga
4021 acgatctcgt aagaaggatt cagtggatgg agagctagaa gctctgatgg aaaatggtga
4081 gggtctctct gataaaaacc aggtgcccag cttatcccgg ctaatggtta gaattgaaac
4141 tttggagcag aaacttacct gtctggaact catacagaac acacactcac agtcctgcct
4201 gaagtccttt ctggaacgtc atgggctgtc tttgttgtgg atctggatgg cagagctagg
4261 tgacggccgg gaaagtaacc agaagcttca ggaagagatt ataaagactt tggagcactt
4321 gcccattcct actaaaaata tgttggagga aagcaaagta cttccaatta ttcaacgctg
4381 gtctcagact aagactgctg tccctccgtt gagtgaagga gatgggtatt ctagtgagaa
4441 tacatcgcgt gctcatacac cactcaacac acctgatcct tccaccaagc tgagcacaga
4501 agctgacaca gacactccca agaaactaat gtttcgcaga ctgaaaatta taagtgaaaa
4561 tagcatggac agtgcaatct ctgatgcaac cagtgagcta gaaggcaagg atggcaaaga
4621 ggatcttgat caattagaaa atgtccctgt agaggaagag gaagaattgc agtcacaaca
4681 gctactccca caacagctgc ctgaatgcaa agttgatagt gaaaccaaca tagaagctag
4741 taagctacct acatctgaac cagaagctga cgctgaaata gagcccaaag agagcaacgg
4801 cacaaaacta gaagaaccta ttaatgaaga aacaccatcc caagatgaag aggagggtgt
4861 gtctgatgtg gagagtgaaa ggagccaaga acagccagat aaaacagtgg atataagtga
4921 tttggccacc aaactcctgg acagttggaa agacctaaag gaggtatatc gaattccaaa
4981 gaaaagtcaa actgaaaagg aaaacacaac aactgaacga ggaagggatg ctgttggctt
5041 cagagatcaa acacctgccc cgaagactcc taataggtca agagagagag acccagacaa
5101 gcaaactcaa aataaagaga aaaggaaacg aagaagctcc ctctcaccac cctcttctgc
5161 ctatgagcgg ggaacaaaaa ggccagatga cagatatgat acaccaactt ctaaaaagaa
5221 agtacgaatt aaagaccgca ataaactttc tacagaggaa cgccggaagt tgtttgagca
5281 agaggtggct caacgggagg ctcagaaaca acagcaacag atgcagaacc tgggaatgac
5341 atcaccactg ccctatgact ctcttggtta taatgccccg catcatccct ttgctggtta
5401 cccaccaggt tatcccatgc aggcctatgt ggatcccagc aaccctaatg ctggaaaggt
5461 gctcctgccc acacccagca tggacccagt gtgttctcct gctccttatg atcatgctca
5521 gcccttggtg ggacattcta cagaacccct ttctgcccct ccaccagtac cagtggtgcc
5581 acatgtggca gctcctgtgg aagtttccag ttcccagtat gtggcccaga gtgatggtgt
5641 agtacaccaa gactccagcg ttgctgtctt gccagtgccg gcccccggcc cagttcaggg
5701 acagaattat agtgtttggg attcaaacca acagtctgtc agtgtacagc agcagtactc
5761 tcctgcacag tctcaagcaa ccatatatta tcaaggacag acatgtccaa cagtctatgg
5821 tgtgacatca ccttattcac agacaactcc accaattgta cagagttatg cccagccaag
5881 tcttcagtat atccaggggc aacagatttt cacagctcat ccacaaggag tggtggtaca
5941 gccagccgca gcagtgacta caatagttgc accagggcag cctcagccct tgcagccatc
6001 tgaaatggtt gtgacaaata atctcttgga tctgccgccc ccctctcctc ccaaaccaaa
6061 aaccattgtc ttacctccca actggaagac agctcgagat ccagaaggga agatttatta
6121 ctaccatgtg atcacaaggc agactcagtg ggatcctcct acttgggaaa gcccaggaga
6181 tgatgccagc cttgagcatg aagctgagat ggacctggga actccaacat atgatgaaaa
6241 ccccatgaag gcctcgaaaa agcccaagac agcagaagca gacacctcca gtgaactagc
6301 aaagaaaagc aaagaagtat tcagaaaaga gatgtcccag ttcatcgtcc agtgcctgaa
6361 cccttaccgg aaacctgact gcaaagtggg aagaattacc acaactgaag actttaaaca
6421 tctggctcgc aagctgactc acggtgttat gaataaggag ctgaagtact gtaagaatcc
6481 tgaggacctg gagtgcaatg agaatgtgaa acacaaaacc aaggagtaca ttaagaagta
6541 catgcagaag tttggggctg tttacaaacc caaagaggac actgaattag agtgactgtt
6601 gggccagggt gggaggatgg gtggtcaggt aagacagact ctagggagag gaaatcctgt
6661 gggcctttct gtcccacccc tgtcagcact gtgctactga tgatacatca ccctggggaa
6721 ttcaaccctg cagatgtcaa ctgaaggcca caaaaatgaa ctccatctac aagtgattac
6781 ctagttgtga gctgttggca tgtggttaga agccatcaga ggtgcaaggg cttagaaaag
6841 accctggcca gacctgactc cactcttaaa cctgggtctt ctccttggcg gtgctgtcag
6901 cgcacagacc catgcgcatc cccacccaca accctttacc ctgatgatct gtattatatt
6961 ttaatgtata tgtgaatata ttgaaaataa tttgttttta aaaaaaaaaa aaaaaaaaaa
//