LOCUS AJ237724 4126 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for thiamine transporter (THTR-1), partial.
ACCESSION AJ237724
VERSION AJ237724.1
KEYWORDS Rfc-like protein; thiamine transporter; THTR-1 protein; trmA gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4126)
AUTHORS Cohen N.A.
JOURNAL Submitted (25-MAR-1999) to the INSDC. Cohen N.A., Genetics,
Technion-Bruce Rappaport Faculty of Medicine, POB 9649, Bat-Galim,
Haifa, 31096, ISRAEL.
REFERENCE 2
AUTHORS Labay V., Raz T., Baron D., Mandel H., Williams H., Barrett T.,
Szargel R., McDonald L., Shalata A., Nosaka K., Gregory S.,
Cohen N.
TITLE Mutations in SLC19A2 cause thiamine-responsive megaloblastic
anaemia associated with diabetes mellitus and deafness
JOURNAL Nat Genet 22(3), 300-304(1999).
PUBMED 10391221
COMMENT Related sequence: AL021068
FEATURES Location/Qualifiers
source 1..4126
/db_xref="H-InvDB:HIT000245219"
/organism="Homo sapiens"
/chromosome="1"
/map="1q23.3"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS <11..1504
/gene="TRMA"
/product="THTR-1 protein"
/function="thiamine transporter"
/db_xref="GOA:O60779"
/db_xref="H-InvDB:HIT000245219.14"
/db_xref="HGNC:HGNC:10938"
/db_xref="InterPro:IPR002666"
/db_xref="InterPro:IPR028338"
/db_xref="InterPro:IPR036259"
/db_xref="UniProtKB/Swiss-Prot:O60779"
/protein_id="CAB50770.1"
/translation="MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFA
SLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVL
LQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSY
CRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFH
HIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRL
LVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNG
GVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYAS
YVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGL
EITTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS"
regulatory 3784..3789
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1078 a 800 c 795 g 1453 t
ORIGIN
1 cgcgccccgg atggatgtgc ccggcccggt gtctcggcgg gcggcggcgg cggcggccac
61 tgtgctcctg cggaccgctc gggtccgtcg cgaatgctgg ttcttgccga ccgcgctgct
121 ctgcgcctac ggcttcttcg ccagcctcag gccgtccgag cccttcctga ccccgtacct
181 gctggggccg gacaagaacc tgaccgagag ggaggtcttc aatgaaattt atccagtatg
241 gacttactct tacctggtgc tactgtttcc tgtgttcctt gccacagact acctccgtta
301 taaacctgtt gttctactgc aggggctcag ccttattgtt acatggttta tgctgctcta
361 tgcccaggga ctgctggcca ttcaatttct agaatttttt tatggcatcg ccacagccac
421 tgaaattgcc tattactctt atatctacag tgtggtggac ctgggcatgt accagaaagt
481 cacaagttac tgtcgaagtg ccactttggt gggctttaca gtgggctctg tcctagggca
541 aatccttgtc tcagtggcag gctggtcgct gttcagcctg aatgtcatct ctcttacctg
601 tgtttcagtg gcttttgctg tggcctggtt tttacctatg ccacagaaga gcctcttctt
661 tcaccacatt ccttctacct gccagagagt gaatggcatc aaggtacaaa atggtggcat
721 tgttactgac accccagctt ctaaccacct tcctggctgg gaggacattg agtcaaaaat
781 ccctctaaat atggaggagc ctcccgtgga ggaaccggaa cccaagccag accgtctcct
841 tgtattgaaa gtactatgga atgatttcct gatgtgctac tcctctcgcc ctcttctctg
901 ctggtctgtg tggtgggccc tctctacctg tggctatttt caagttgtga actacacaca
961 gggcctgtgg gagaaagtga tgccttctcg ctatgctgct atctataatg gtggcgtgga
1021 ggccgtttca accttactgg gtgctgttgc tgtgtttgca gttggttata taaaaatatc
1081 ctggtcaact tggggagaaa tgacattatc tctcttttct ctcctgattg ctgctgcagt
1141 gtatatcatg gacactgtgg gtaacatttg ggtgtgctat gcatcctatg ttgtcttcag
1201 aatcatctac atgttactca tcacgatagc aacttttcaa attgctgcaa acctcagcat
1261 ggaacgctat gccctagtat ttggtgtaaa taccttcatt gccctggcac tgcagacgct
1321 gctcactcta attgtggtag atgccagtgg ccttggatta gaaattacca ctcagttttt
1381 gatctatgcc agttattttg cactcatcgc tgtggttttc ctggccagtg gtgcagtcag
1441 tgttatgaag aaatgtagaa agctggaaga tccacaatca agttctcaag taaccacttc
1501 ataatatact gctgaagggc ttcttcttat agcaagaact ctgcacagca actgcctgga
1561 tgtgtttgat tttttaaagc gtagacatat atttatgaat gtgcatttct tgacttcaca
1621 gcagccactt gactaatacc ttgtgttccg ggaataacat gatactattc agaggagcca
1681 gaagtaaagt ttatttcatg gattatttat gagagctaat ttaaggatga ctttttttct
1741 gattcaaaag tgaacttgat tttaaaaacc agtcaagagc aatcaaagca gcacatggtg
1801 ttgtatactt cattagcaag tgagtttggt gttttatagg tcacatatgt ctgtatctac
1861 ttagccagat gcttggcctg gtgggaccag ggctccacag aggccacaaa atgttgcaag
1921 tcatgatgga tggaaatatg ttctaacagc atctgcctct attcaattta attcttattt
1981 ctgtgttact catgtacatt ggtctttcta catagttatt ctatcactgg caatatttgt
2041 tctggtttag tgttctgtat tttaaggtgt acgtatcatt tctaatttta agttatttta
2101 aaaaaattca tcatatgaat gttcttggtt cccattgtga cgattattta tttctgtaaa
2161 atttgtttag aagtacgttt ttgcattatt catatgcttc ccagagaagc tcatttagtt
2221 agaaaataag gcaagttttg aagcctgcta aatgaagaga cttaagaaag cttaaggtac
2281 gcttgcttgt ctttaaatct tcaatatgaa ggactattaa ttccaagatt aaaagttcat
2341 atataggcta aagatgtaac taggccattt gtatttgtat tcccttttat ttccaaaata
2401 aaatgaaaaa tcttttttta ataatttcat ccctatttat agtttttata ttaatttgtt
2461 tttcttatcc aagtaaagat gtcaatagga attgcattag tccaaggcct ttttcataaa
2521 ctgagcctct tttcaattat ttcaatggga caggaactag gatagatgtg attcctgcat
2581 ttttttacct taaatctgcc tttgtttcta aaggtagatc atcttgaata tttgcttaaa
2641 attgctagtg atttcattac caagttactt gaaaaaatgt tctatatgca tttaattctg
2701 aaatcagtct accaaggggc tgctagtata tgtcagacat gaaaactatt ttaaagctga
2761 ctttgttgcc ttatcttgaa aagaatctag ataggtgctt ttaactgggg tattaacttt
2821 tttagaatga cacagctgaa cagtgttaat aatagtgtgt caagattgca aagtcgacat
2881 actcatttgg tttaagcagg aatcctagaa gcaaatggat ggggataaga ataggtcatt
2941 ttctattcac catcctttac tattaaggga aaggaaaaga acactagcta aggaagggaa
3001 agggaagtga tatcataaaa gtagcaacct tcattttaca ttctgtctgt ttttcttttt
3061 ttgctttgtt ttgtttgtgc taatttggga attgtgtact ccgaaacaag tagaaaagtg
3121 ctgtttgagg gattttatta aatctttttt taatggaatg tggtacaaat tgttcatgtt
3181 accaaagcaa tatttccctg gaatttaatt caaagtttgt ggcatacaac ctgagccttt
3241 tcttatataa gacaagaata tgttcacatc ttggtatgtg gccatattta tagaatgctg
3301 aactcaatgt gcaagttgta ctgtatgcag ttttgtaaat aagtgaaaat aatttgttgt
3361 actttttatt caattctgta tagattataa aattattttt attaaataaa tattttacag
3421 tatattttct ctttttaatc aaaattgttt taaatttatc ttctatttca gtaggagctt
3481 tagattatat ctttaaatat tttaataatt tatcctagga caaatttcat attaagtctt
3541 cccctggtct aacttgccta gttaaccttt tgttatcttt ttaattattc cattgctttg
3601 tgatttttac ctttgactct tcccccttat ttcagatgtt ttcccccttt tttttggcac
3661 cccgttgcac tgtttttttt tttttttttg gttttcatgt tggcactgct cttatctctt
3721 tttaaagcat tcttccttaa aaaaaaaaaa agacactctc tttgatgtta actgaatttt
3781 tacaataaag gaaattaaag caagagcaga aaataccacc ttgttctgaa acttcatagc
3841 ctctttgttc cacctcaaat tattctgata cccagggagg aatcttcttg ccatgagttg
3901 agaatcattt gtccattata tcccagaaac ctaatcagta ttttcttaca gtatccaaat
3961 gagtaccatt ttttaatata ccatttcaaa atctacttaa ggcattgatt tcgctgctta
4021 tcaccaaagt cctggaaatt tttcatgcaa aaataaattt tttttttttg agacagtctt
4081 gcactgttgc ccaggctgca gtgcagtggc aatctcggct cactgc
//