LOCUS AJ236921 3223 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for metabotropic glutamate receptor 8b.
ACCESSION AJ236921
VERSION AJ236921.1
KEYWORDS metabotropic glutamate receptor 8b; mGluR8b gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3223)
AUTHORS Malherbe P.
JOURNAL Submitted (15-FEB-1999) to the INSDC. Malherbe P., PRPN, F.
Hoffmann-La Roche, Ltd., Building 69/333, CH-4070 Basel,
SWITZERLAND.
REFERENCE 2
AUTHORS Malherbe P., Kratzeisen C., Lundstrom K., Richards J.G.,
Faull R.L.M., Mutel V.
TITLE Cloning and functional expression of alternative spliced variants
of the human metabotropic glutamate receptor 8
JOURNAL Brain Res. Mol. Brain Res. 67(2), 201-210(1999).
PUBMED 10216218
FEATURES Location/Qualifiers
source 1..3223
/db_xref="H-InvDB:HIT000245213"
/organism="Homo sapiens"
/chromosome="7"
/map="7q31-3-q32.1"
/mol_type="mRNA"
/tissue_type="fetal brain"
/db_xref="taxon:9606"
CDS 16..2742
/gene="mGluR8b"
/product="metabotropic glutamate receptor 8b"
/note="HmGluR8b; group III"
/db_xref="GOA:O00222"
/db_xref="H-InvDB:HIT000245213.12"
/db_xref="HGNC:HGNC:4600"
/db_xref="InterPro:IPR000144"
/db_xref="InterPro:IPR000162"
/db_xref="InterPro:IPR000337"
/db_xref="InterPro:IPR001828"
/db_xref="InterPro:IPR011500"
/db_xref="InterPro:IPR017978"
/db_xref="InterPro:IPR017979"
/db_xref="InterPro:IPR028082"
/db_xref="InterPro:IPR038550"
/db_xref="PDB:6BSZ"
/db_xref="PDB:6BT5"
/db_xref="PDB:6E5V"
/db_xref="UniProtKB/Swiss-Prot:O00222"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB36968.1"
/translation="MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDG
DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI
LDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI
MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYV
STLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNAR
AVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPK
RASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIAR
DSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVN
FNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHRE
HTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNR
TGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYV
LLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKK
SVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVL
KCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFI
PIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSF
KAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFPMVKSGSTS"
BASE COUNT 922 a 712 c 747 g 842 t
ORIGIN
1 ccacctgtgg agaaaatggt atgcgaggga aagcgatcag cctcttgccc ttgtttcttc
61 ctcttgaccg ccaagttcta ctggatcctc acaatgatgc aaagaactca cagccaggag
121 tatgcccatt ccatacgggt ggatggggac attattttgg ggggtctctt ccctgtccac
181 gcaaagggag agagaggggt gccttgtggg gagctgaaga aggaaaaggg gattcacaga
241 ctggaggcca tgctttatgc aattgaccag attaacaagg accctgatct cctttccaac
301 atcactctgg gtgtccgcat cctcgacacg tgctctaggg acacctatgc tttggagcag
361 tctctaacat tcgtgcaggc attaatagag aaagatgctt cggatgtgaa gtgtgctaat
421 ggagatccac ccattttcac caagcccgac aagatttctg gcgtcatagg tgctgcagca
481 agctccgtgt ccatcatggt tgctaacatt ttaagacttt ttaagatacc tcaaatcagc
541 tatgcatcca cagccccaga gctaagtgat aacaccaggt atgacttttt ctctcgagtg
601 gttccgcctg actcctacca agcccaagcc atggtggaca tcgtgacagc actgggatgg
661 aattatgttt cgacactggc ttctgagggg aactatggtg agagcggtgt ggaggccttc
721 acccagatct cgagggagat tggtggtgtt tgcattgccc agtcacagaa aatcccacgt
781 gaaccaagac ctggagaatt tgaaaaaatt atcaaacgcc tgctagaaac acctaatgct
841 cgagcagtga ttatgtttgc caatgaggat gacatcagga ggatattgga agcagcaaaa
901 aaactaaacc aaagtgggca ttttctctgg attggctcag atagttgggg atccaaaata
961 gcacctgtct atcagcaaga ggagattgca gaaggggctg tgacaatttt gcccaaacga
1021 gcatcaattg atggatttga tcgatacttt agaagccgaa ctcttgccaa taatcgaaga
1081 aatgtgtggt ttgcagaatt ctgggaggag aattttggct gcaagttagg atcacatggg
1141 aaaaggaaca gtcatataaa gaaatgcaca gggctggagc gaattgctcg ggattcatct
1201 tatgaacagg aaggaaaggt ccaatttgta attgatgctg tatattccat ggcttacgcc
1261 ctgcacaata tgcacaaaga tctctgccct ggatacattg gcctttgtcc acgaatgagt
1321 accattgatg ggaaagagct acttggttat attcgggctg taaattttaa tggcagtgct
1381 ggcactcctg tcacttttaa tgaaaacgga gatgctcctg gacgttatga tatcttccag
1441 tatcaaataa ccaacaaaag cacagagtac aaagtcatcg gccactggac caatcagctt
1501 catctaaaag tggaagacat gcagtgggct catagagaac atactcaccc ggcgtctgtc
1561 tgcagcctgc cgtgtaagcc aggggagagg aagaaaacgg tgaagggggt cccttgctgc
1621 tggcactgtg aacgctgtga aggttacaac taccaggtgg atgagctgtc ctgtgaactt
1681 tgccctctgg atcagagacc caacatgaac cgcacaggct gccagcttat ccccatcatc
1741 aaattggagt ggcattctcc ctgggctgtg gtgcctgtgt ttgttgcaat attgggaatc
1801 atcgccacca cctttgtgat cgtgaccttt gtccgctata atgacacacc tatcgtgagg
1861 gcttcaggac gcgaacttag ttacgtgctc ctaacgggga tttttctctg ttattcaatc
1921 acgtttttaa tgattgcagc accagataca atcatatgct ccttccgacg ggtcttccta
1981 ggacttggca tgtgtttcag ctatgcagcc cttctgacca aaacaaaccg tatccaccga
2041 atatttgagc aggggaagaa atctgtcaca gcgcccaagt tcattagtcc agcatctcag
2101 ctggtgatca ccttcagcct catctccgtc cagctccttg gagtgtttgt ctggtttgtt
2161 gtggatcccc cccacatcat cattgactat ggagagcagc ggacactaga tccagagaag
2221 gccaggggag tgctcaagtg tgacatttct gatctctcac tcatttgttc acttggatac
2281 agtatcctct tgatggtcac ttgtactgtt tatgccatta aaacgagagg tgtcccagag
2341 actttcaatg aagccaaacc tattggattt accatgtata ccacctgcat catttggtta
2401 gctttcatcc ccatcttttt tggtacagcc cagtcagcag aaaagatgta catccagaca
2461 acaacactta ctgtctccat gagtttaagt gcttcagtat ctctgggcat gctctatatg
2521 cccaaggttt atattataat ttttcatcca gaacagaatg ttcaaaaacg caagaggagc
2581 ttcaaggctg tggtgacagc tgccaccatg caaagcaaac tgatccaaaa aggaaatgac
2641 agaccaaatg gcgaggtgaa aagtgaactc tgtgagagtc ttgaaaccaa cagtaagtca
2701 tctgtagagt ttccgatggt caagagcggg agcacttcct aatagatctt cctctaccaa
2761 gacaacatat atcagttaca gcaatcattc aatctgaaac agggaaatgg cacaatctga
2821 agagatgtgg tatatgatct taaatgatga acatgagacc gcaaaaattc actcctggag
2881 atctccgtag actacaatca atcaaatcaa tagtcagtct tgtaaggaac aaaaattagc
2941 catgagccaa aagtatcaat aaacggggag tgaagaaacc cgttttatac aataaaacca
3001 atgagtgtca agctaaagta ttgcttattc atgagcagtt aaaacaaatc acaaaaggaa
3061 aactaatgtt agctcgtgaa aaaaatgctg ttgaaataaa taatgtctga tgttattctt
3121 gtatttttct gtgattgtga gaactcccgt tcctgtccca cattgtttaa cttgtataag
3181 acaatgagtc tgtttcttgt aatggctgac cagattgaag ccc
//