LOCUS AJ224866 1310 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for pancreatic procarboxypeptidase B.
ACCESSION AJ224866
VERSION AJ224866.1
KEYWORDS carboxypeptidase B.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1310)
AUTHORS Aviles F.
JOURNAL Submitted (05-MAR-1998) to the INSDC. Aviles F., Bioquimica i
Biologia Molecular, Universitat Autonoma de Barcelona, Cerdanyola
08193, Cerdanyola 08193, SPAIN.
REFERENCE 2 (bases 1 to 1310)
AUTHORS Aloy P., Catasus L., Villegas V., Reverter D., Vendrell J.,
Aviles F.X.
TITLE Comparative analysis of the sequences and three-dimensional models
of human procarboxypeptidases A1, A2 and B
JOURNAL Biol. Chem. 379(2), 149-155(1998).
PUBMED 9524066
FEATURES Location/Qualifiers
source 1..1310
/db_xref="H-InvDB:HIT000244985"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_type="pancreas"
/db_xref="taxon:9606"
sig_peptide 5..50
CDS 6..1259
/product="procarboxypeptidase B"
/function="zymogen of pancreatic carboxypeptidase B"
/EC_number="3.4.17.2"
/note="inactive precursor of carboxypeptidase B"
/db_xref="GOA:P15086"
/db_xref="H-InvDB:HIT000244985.13"
/db_xref="HGNC:HGNC:2299"
/db_xref="InterPro:IPR000834"
/db_xref="InterPro:IPR003146"
/db_xref="InterPro:IPR036990"
/db_xref="PDB:1KWM"
/db_xref="PDB:1ZLI"
/db_xref="UniProtKB/Swiss-Prot:P15086"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAA12163.1"
/translation="MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIREL
ASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVE
AQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVG
KAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVL
NIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPA
AESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKAT
VKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPES
QIRATCEETFLAIKYVASYVLEHLY"
mat_peptide 51..1256
/product="procarboxypeptidase B"
BASE COUNT 353 a 316 c 305 g 336 t
ORIGIN
1 gcacaatgtt ggcactcttg gttctggtga ctgtggccct ggcatctgct catcatggtg
61 gtgagcactt tgaaggcgag aaggtgttcc gtgttaacgt tgaagatgaa aatcacatta
121 acataatccg cgagttggcc agcacgaccc agattgactt ctggaagcca gattctgtca
181 cacaaatcaa acctcacagt acagttgact tccgtgttaa agcagaagat actgtcactg
241 tggagaatgt tctaaagcag aatgaactac aatacaaggt actgataagc aacctgagaa
301 atgtggtgga ggctcagttt gatagccggg ttcgtgcaac aggacacagt tatgagaagt
361 acaacaagtg ggaaacgata gaggcttgga ctcaacaagt cgccactgag aatccagccc
421 tcatctctcg cagtgttatc ggaaccacat ttgagggacg cgctatttac ctcctgaagg
481 ttggcaaagc tggacaaaat aagcctgcca ttttcatgga ctgtggtttc catgccagag
541 agtggatttc tcctgcattc tgccagtggt ttgtaagaga ggctgttcgt acctatggac
601 gtgagatcca agtgacagag cttctcaaca agttagactt ttatgtcctg cctgtgctca
661 atattgatgg ctacatctac acctggacca agagccgatt ttggagaaag actcgctcca
721 cccatactgg atctagctgc attggcacag accccaacag aaattttgat gctggttggt
781 gtgaaattgg agcctctcga aacccctgtg atgaaactta ctgtggacct gccgcagagt
841 ctgaaaagga gaccaaggcc ctggctgatt tcatccgcaa caaactctct tccatcaagg
901 catatctgac aatccactcg tactcccaaa tgatgatcta cccttactca tatgcttaca
961 aactcggtga gaacaatgct gagttgaatg ccctggctaa agctactgtg aaagaacttg
1021 cctcactgca cggcaccaag tacacatatg gcccgggagc tacaacaatc tatcctgctg
1081 ctgggggctc tgacgactgg gcttatgacc aaggaatcag atattccttc acctttgaac
1141 ttcgagatac aggcagatat ggctttctcc ttccagaatc ccagatccgg gctacctgcg
1201 aggagacctt cctggcaatc aagtatgttg ccagctacgt cctggaacac ctgtactagt
1261 tgagaaagct gatggccttg tttcaaaatt ctcatttttc atttcttttc
//