LOCUS AJ224328 2896 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for MOCS1A & MOCS1B proteins, complete CDSs.
ACCESSION AJ224328
VERSION AJ224328.1
KEYWORDS MOCS1 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2896)
AUTHORS Reiss J.P.
JOURNAL Submitted (13-FEB-1998) to the INSDC. Reiss J.P., Human Genetics,
University of Goettingen, Gosslerstrasse 12d, 37073 Goettingen,
GERMANY.
REFERENCE 2
AUTHORS Reiss J.P., Cohen N., Dorche C., Mandel H., Mendel R.R.,
Stallmeyer B., Zabot M.T., Dierks T.
TITLE Mutations in a polycistronic nuclear gene associated with
molybdenum cofactor deficiency
JOURNAL Nat Genet 20(1), 51-53(1998).
PUBMED 9731530
REFERENCE 3
AUTHORS Reiss J.P., Christensen E., Kurlemann G., Zabot M.T., Dorche C.
TITLE Genomic structure and mutational spectrum of the bicistronic MOCS1
gene defective in molybdenum cofactor deficiency type A
JOURNAL Hum. Genet. 103(6), 639-644(1998).
PUBMED 9921896
FEATURES Location/Qualifiers
source 1..2896
/db_xref="H-InvDB:HIT000244971"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 136..1293
/gene="MOCS1"
/product="MOCS1A protein"
/db_xref="GOA:Q9NZB8"
/db_xref="H-InvDB:HIT000244971.14"
/db_xref="HGNC:HGNC:7190"
/db_xref="InterPro:IPR000385"
/db_xref="InterPro:IPR002820"
/db_xref="InterPro:IPR006638"
/db_xref="InterPro:IPR007197"
/db_xref="InterPro:IPR010505"
/db_xref="InterPro:IPR013483"
/db_xref="InterPro:IPR013785"
/db_xref="InterPro:IPR023045"
/db_xref="InterPro:IPR036522"
/db_xref="UniProtKB/Swiss-Prot:Q9NZB8"
/protein_id="CAA11897.1"
/translation="MWKSWKLRTDVRVREGAGGSPCASSQPGSRGPCFLPGLSSQEVS
RRRQFLREHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLL
TTEEILTLARLFVKEGIDKIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINL
ARLLPQLQKAGLSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNC
VVMRGLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWP
ELEKVPEEESSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNS
EVSLRDHLRAGASEQELLRIIGAAVGRKKRQHAGMFSISQMKNRPMILIGG"
primer_bind complement(256..276)
/note="mcsT"
primer_bind complement(277..297)
/note="mcsS"
primer_bind 361..386
/note="HumI"
primer_bind 442..461
/note="HumII"
CDS 1390..2061
/gene="MOCS1"
/product="MOCS1B protein"
/db_xref="GOA:Q9NZB8"
/db_xref="HGNC:HGNC:7190"
/db_xref="InterPro:IPR000385"
/db_xref="InterPro:IPR002820"
/db_xref="InterPro:IPR006638"
/db_xref="InterPro:IPR007197"
/db_xref="InterPro:IPR010505"
/db_xref="InterPro:IPR013483"
/db_xref="InterPro:IPR013785"
/db_xref="InterPro:IPR023045"
/db_xref="InterPro:IPR036522"
/db_xref="UniProtKB/Swiss-Prot:Q9NZB8"
/protein_id="CAA11898.1"
/translation="MSFSSQVATLWKGCRVPQTPPLAQQRLGSGSFQRHYTSRADSDA
NSKCLSPGSWASAAPSGPQLTSEQLTHVDSEGRAAMVDVGRKPDTERVAVASAVVLLG
PVAFKLVQQNQLKKGDALVVAQLAGVQAAKVTSQLIPLCHHVALSHIQVQLELDSTRH
AVKIQASCRARGPTGVEMEALTSAAVAALTLYDMCKAVSRDIVLEEIKLISKTGGQRG
DFHRA"
BASE COUNT 643 a 865 c 777 g 611 t
ORIGIN
1 gccagaaatc ttcccagtag agatcaccat ccgcccccga cccccaagaa tacttaaggg
61 gtgggtcctt cccatcaagc tgatttctca acgagaggga caatcccagc ttccccaaca
121 ttgcagagcc caaacatgtg gaagagttgg aagctccgca cagatgtcag agtaagggag
181 ggggcaggcg gttctccttg tgcctcttcc cagcccggta gcaggggccc atgcttcctc
241 cctggtctgt cctcgcagga ggtgtccagg cggaggcagt tcctgcggga gcatgcggcc
301 cccttctccg ccttcctcac agacagcttc ggccggcagc acagctacct gcggatctcc
361 ctcacagaga agtgcaacct cagatgtcag tactgcatgc ccgaggaggg ggtcccgctg
421 acccccaaag ccaacctgct gaccacagag gagatcctga ccctcgcccg gctctttgtg
481 aaggaaggca tcgacaagat ccggctcaca ggtggagagc cgcttatccg gccggacgtg
541 gtggacattg tggcccagct ccagcggctg gaagggctga gaaccatagg tgttaccacc
601 aatggcatca acctggcccg gctactgccc cagcttcaga aggctggtct cagtgccatc
661 aacatcagcc tggacaccct ggtgcctgcc aagtttgagt tcattgtccg caggaaaggc
721 ttccacaagg tcatggaggg catccacaag gccatcgagc tgggctacaa ccctgtgaag
781 gtgaactgtg tggtgatgcg aggccttaac gaggatgaac tcctggactt tgcggccttg
841 actgagggcc tccccctgga tgtgcgcttc atagagtata tgccctttga tggcaacaag
901 tggaacttca agaagatggt cagctataag gagatgctag acactgtccg gcagcagtgg
961 ccagagctgg agaaggtgcc agaggaggaa tccagcacag ccaaggcctt taaaatccct
1021 ggcttccaag gccagatcag cttcatcaca tccatgtctg agcatttctg tgggacctgc
1081 aaccgcctgc gaatcacagc tgatgggaac ctcaaggtct gcctctttgg aaactctgag
1141 gtatccctgc gggatcacct gcgagctggg gcctctgagc aggagctgct gagaatcatt
1201 ggggctgctg tgggcaggaa gaagcggcag catgcaggca tgttcagtat ttcccagatg
1261 aagaaccggc ccatgatcct catcggtggg tgacccatca agttattttt gatgttcccc
1321 aattccccac cagccaatcc aagcattttc tcctgggacc cgctccatgt tcagggtcta
1381 agacccagaa tgagtttctc cagccaggtg gccactttat ggaaaggatg cagggtcccc
1441 cagacccctc ctctagccca gcagcggctg gggtctggct cctttcagag acactacact
1501 tcccgtgcag actcagatgc caactcaaag tgccttagcc caggttcctg ggcttctgct
1561 gccccctcag gaccccagct aacctcagaa caactaactc atgtggactc ggaaggacgg
1621 gcagctatgg tagatgtggg caggaagcca gacacagagc gggtggctgt ggcttcagcc
1681 gtggtcctcc tgggaccggt agccttcaag cttgtccagc agaaccagct caagaaagga
1741 gatgccctag tggtggccca gctggctgga gtccaggcag ccaaggtgac cagccagctg
1801 atccctctgt gccaccacgt ggccctgagc cacatccagg tgcagctgga gctggacagc
1861 acacgccatg ccgtgaagat ccaggcatct tgccgggctc ggggccccac cggggtggag
1921 atggaggccc tgacctctgc tgcagtggcc gccctcaccc tgtatgacat gtgcaaggct
1981 gtcagcaggg acatcgtgtt ggaggagatc aagctcatta gcaagactgg tggtcagcgg
2041 ggggacttcc atcgggctta gcacctgccc ttctcaccca tggcccaccc aggcctggag
2101 ctgggatgca atgtaggctg agggaaagac gtcaggttcc tttaatcaca gtcactgttt
2161 gtttaccttg agcagtaaac ccgaagtcag cctgctctac tactaacaaa caggcctgct
2221 gctagatgat ctctaatgac caatggggct tcctttctat agggaggata ccagcaggcc
2281 cttaagcctt ccaggacact aaggtcgtgg gagcgggact gcaacaagca atgccagata
2341 actgagaaat catgttcttt gtggactatt tcagacaacc aggttccgac agtccagccc
2401 agaacttttc cttctcattt tgggttttct cttctcctgc tttcctgggg agagattaag
2461 cgctcattaa gcagaggagc ccactttgag gagagcaaag cacaagcttg cctgaagaat
2521 ggatcccaac ctctccccgg cagctctgcc tccctaagtt tgtgaagccg cagccctgcc
2581 ctgtcctgtc ctgtcctgac ttcatctctc cttctgccca agtctgtgtc ccatcagact
2641 tgcagccttt cagcttaaca gttgcccggt cctgctggcc ccttttcctc tggcccccct
2701 cttctgaaac aggatgtgca cacatgggcc atagccctaa ggactcctgc cagaccacac
2761 agcccacacc tggccctgtt cacggctgtt ccacgcaccc ctctttattc tggagcatat
2821 cagggaaaga aaagttgatg atagattgcc ttcaccctca cagcgcacaa ataaagctac
2881 gatgccaact ttgaaa
//