LOCUS AJ223948 4470 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for putative RNA helicase, 3' end.
ACCESSION AJ223948
VERSION AJ223948.1
KEYWORDS RNA helicase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4470)
AUTHORS Baurain J.F.
JOURNAL Submitted (04-FEB-1998) to the INSDC. Baurain J.-F., Catholic
University of Louvain, Cellular Genetics Unit, 74, av. Hippocrate
(UCL 7459), B-1200 Brussels, BELGIUM.
REFERENCE 2
AUTHORS Baurain J.F.
TITLE The immunodominant antigen recognized by autologous CTL on a human
melanoma is generated by a point mutation in a new member of the
RNA helicase gene family
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..4470
/db_xref="H-InvDB:HIT000244849"
/organism="Homo sapiens"
/chromosome="6"
/map="q15-16"
/mol_type="mRNA"
/sex="female"
/clone_lib="library of JF Baurain"
/clone="B4"
/cell_line="LB33-MEL.A-1 (tumor cell line)"
/tissue_type="tumor-melanoma"
/db_xref="taxon:9606"
CDS <1..3774
/codon_start=1
/product="RNA helicase"
/note="putative"
/db_xref="GOA:Q8N3C0"
/db_xref="H-InvDB:HIT000244849.14"
/db_xref="HGNC:HGNC:18697"
/db_xref="InterPro:IPR001650"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR004179"
/db_xref="InterPro:IPR011545"
/db_xref="InterPro:IPR014001"
/db_xref="InterPro:IPR014756"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR035892"
/db_xref="InterPro:IPR036390"
/db_xref="UniProtKB/Swiss-Prot:Q8N3C0"
/protein_id="CAA11679.1"
/translation="HKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTD
LGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLL
SNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEI
ALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDM
RKDEIGHILHHVNIGLKVKQCVHQIPSVMMEAFIQPITRTVLRVTLSIYADFTWNDQV
HGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIR
AVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFN
PVQTQIFHTLYHTDSNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVR
ERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYV
QQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADW
LNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLI
FVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGM
HHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYV
DFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDH
LNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSL
IELELSYCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILS
DAEEYTDLPVRHNEDHMNSELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPD
YDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPN
IENHHLHLFKKWKPIMKGPHARGRTSIECLPELIHACGGKDHVFSSMVESELHAAKTK
QAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVL
QVSLQRVHFGFHKGKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHH
VASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQYDNLSQRYTSESFCTGQHQGL"
regulatory 4432..4440
/regulatory_class="polyA_signal_sequence"
polyA_site 4457
BASE COUNT 1413 a 882 c 909 g 1266 t
ORIGIN
1 cacaaggctt atcagattga cccaacatta agaaagcatc gagaacagtt ggtcattgaa
61 gttggacgaa aactagacaa agctcagatg attcgttttg aggagcgaac tggatatttt
121 tcctcaactg atttgggtag aactgccagc cattactata ttaaatacaa caccattgag
181 acctttaatg aactctttga tgctcacaaa acagaaggtg atatctttgc catagtctcc
241 aaagctgaag aatttgatca aattaaggtc agagaagagg aaatagagga gttagatacc
301 ttattaagca atttttgtga actctccact cctggaggtg tagagaatag ttatgggaaa
361 ataaacatct tacttcaaac ttatatcagc cgaggagaaa tggacagttt ctcccttata
421 tcagattctg catatgttgc acagaatgca gctagaattg tccgtgctct ttttgaaatt
481 gctctgagga aacgttggcc taccatgacc tacaggctcc tgaatcttag taaagtcatt
541 gacaagaggc tttggggttg ggctagccct ttgagacaat tttcaatcct accaccacac
601 atcctaacaa gattagaaga aaaaaagctt actgtggata agctgaaaga catgaggaaa
661 gatgaaatag gtcacatttt acatcatgtg aatattggac tgaaggtcaa acaatgtgtt
721 catcagattc cttctgttat gatggaagca ttcattcagc ctatcacaag gactgtcctc
781 cgagtgacac tcagcatcta tgctgatttc acttggaatg atcaggtaca tgggacagta
841 ggagaacctt ggtggatttg ggtagaagat cctacaaatg atcatattta tcattcagag
901 tattttctag ctctaaaaaa acaagtcatt agtaaagaag cccaactact ggtatttaca
961 atccctattt ttgagccttt gccttcccaa tactacatcc gagcagtgtc tgatagatgg
1021 ttgggtgctg aggcagtatg tattatcaac tttcaacatc taattctacc agagagacat
1081 cctcctcata cagaattact ggatcttcag cctttaccaa tcacagcttt gggatgtaaa
1141 gcatatgaag ccctgtacaa cttcagccac tttaaccctg tacagacaca aatatttcat
1201 acattgtatc acacggattc taatgtccta cttggagcac ctactggatc gggaaagact
1261 gttgcagctg aattagccat tttcagagtc ttcaacaaat accctacttc aaaggcggta
1321 tatattgcac ccctaaaagc cctagtacgt gaaagaatgg atgattggaa agttagaata
1381 gaagaaaaac ttggtaaaaa agttattgaa ctaacagggg atgtgactcc tgatatgaaa
1441 tccattgcca aggctgacct tatcgtcact acgccagaga agtgggatgg agtcagcaga
1501 agctggcaaa ataggaacta tgttcagcaa gtcactattc tcatcataga tgagatccat
1561 ctgcttgggg aggaaagagg ccctgttcta gaggtcattg tatctcgaac aaattttatc
1621 tcatcacaca cagaaaagcc tgttagaata gttggactat ctactgcatt agctaatgcc
1681 agagaccttg ctgattggct caatattaag cagatgggct tgtttaactt ccgaccatca
1741 gtacgcccag ttccactgga agttcacatt caaggctttc caggtcaaca ttactgtcct
1801 cgtatggcta gtatgaacaa gcctgcattt caggcaatta gaagccattc tccagccaaa
1861 cctgttttga tatttgtctc atcaagacgt caaactcgtc ttactgcttt ggaattgatc
1921 gccttcctgg ctactgaaga agatccaaag cagtggttaa acatggatga aagagagatg
1981 gagaacatca ttgcaacagt aagagattcc aacctcaagc tgacccttgc tttcgggata
2041 ggaatgcatc atgctggact acatgagagg gaccgaaaaa cagtagagga actatttgta
2101 aactgtaaag ttcaggttct tattgctaca agcacattag cctggggtgt aaactttcca
2161 gctcatttag taattattaa gggaacagaa tactatgatg gaaaaacaag acgttatgtg
2221 gattttccca ttacagatgt cctccagatg atggggcgtg ctgggaggcc gcagttcgat
2281 gaccaaggca aagctgtaat tctagttcat gacataaaga aagactttta taaaaaattt
2341 ctttatgaac ctttcccagt agaatcaagt ttattaggag tgctctctga ccacttaaat
2401 gcagagattg ctggtggtac aattacatct aagcaagatg cattggatta tatcacctgg
2461 acttactttt tccgacgtct tatcatgaat cccagctatt acaatttggg tgatgtgagc
2521 catgattctg tgaacaagtt tctgtcccat ctgattgaga agtccctgat tgaattggaa
2581 ctttcctact gtattgaaat tggagaggat aatcgcagca ttgaacctct aacttatggc
2641 cgaattgcct cctattacta tttgaagcat caaacagtta aaatgttcaa ggaccgcttg
2701 aagcctgaat gcagtactga agaactgctt tcaattctaa gtgatgcaga agaatataca
2761 gatttgccag tgagacacaa tgaagatcat atgaatagtg aactggcaaa atgtcttccc
2821 attgaatcaa atcctcattc atttgacagc cctcacacca aagcacatct cctgctacag
2881 gcacatctca gccgagccat gctaccctgc ccagattatg acactgatac caaaacagtc
2941 ttggaccaag ctctcagagt atgtcaggca atgctggacg tggctgcaaa ccagggctgg
3001 ctggtgactg tcctgaatat caccaacctg attcagatgg tgatccaggg tcggtggtta
3061 aaggactctt ctcttcttac actaccaaac atagaaaacc atcatcttca ccttttcaag
3121 aaatggaagc cgattatgaa gggcccacat gctaggggtc ggacctccat cgagtgcctt
3181 cctgaactga tccatgcctg tggagggaaa gaccatgtat ttagctccat ggtagaaagt
3241 gagctacatg ctgcaaaaac gaaacaggca tggaatttct tatctcactt gccagtgata
3301 aatgttggca taagtgttaa aggctcgtgg gatgacttag ttgaaggaca taatgaactc
3361 tctgtctcaa ctctgactgc agacaaacga gatgacaaca aatggatcaa attgcatgct
3421 gaccaagagt atgtgcttca agtgagcttg cagagagtcc actttgggtt ccacaaggga
3481 aagccagaga gctgtgcagt tactcctcga tttcccaaat caaaagacga aggatggttt
3541 ttgatattag gagaagtgga taagagagaa cttattgctt tgaaaagagt aggatatatt
3601 cgaaatcatc atgttgcttc cctttctttt tatacccctg aaatacctgg aaggtatatc
3661 tacacattat atttcatgag cgactgctac cttggcctgg accagcagta tgacaatcta
3721 tctcaacgtt acacaagcga gtctttctgc acaggtcaac accaaggtct ctgattccct
3781 gactgacctg gcattaaagt aacttgacct gaacaatcca tttgaaagga gtggctaaga
3841 attctctctg ttcagtcatc tagacaaatc gaattacttg atgtttgcct tgaaagaatc
3901 aacttctaac ctcaaccatc caggaaattg acagtggctg cagtattgac tccagtgaca
3961 taaagttaac cacagtggcc ttttaacaaa tgttgccttt tataatgtta tctttatgag
4021 tttcttgata tgtaagatga aaaagcattt agaataatct tttaatttgt gtatatttgg
4081 gatgatattt aggagctatc aatcaaattt tacatctcac aatgtactgt ttacatggat
4141 attggctgct ttttttaagg aaaaccacat tgagatgtga caagtgttag gacttgtcac
4201 agatttctaa ctctgccgca taaactataa atctgtaagg tggtacacag cgtgtcttgt
4261 tagcaaaatt tatactttga tatgatcaca tgtagaagta gcttcaagaa tttcttgtag
4321 tcataaatgt ttaataatat atgatgtaaa attatattat ggagcctaat gatgataaca
4381 aagaaaacaa tatactgatc ttagaaaatg tagacatggt taactgggaa ataaaatata
4441 gagtggcact tcaagacaaa aaaaaaaaaa
//