LOCUS AJ012590 2853 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for glucose 1-dehydrogenase.
ACCESSION AJ012590
VERSION AJ012590.1
KEYWORDS Glucose 1-dehydrogenase; h6PD gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2853)
AUTHORS Mason P.J.
JOURNAL Submitted (05-NOV-1998) to the INSDC. Mason P.J., Haematology,
Imperial College School of Medicine, Hammersmith Hospital, Ducane
Road, London W12 0NN, UK.
REFERENCE 2
AUTHORS Mason P.J., Stevens D., Diez A., Knight S.W., Scopes D.A.,
Vulliamy T.J.
TITLE Human hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
encoded at 1p36: coding sequence and expression
JOURNAL Blood Cells Mol. Dis. 25(1), 30-37(1999).
PUBMED 10349511
FEATURES Location/Qualifiers
source 1..2853
/db_xref="H-InvDB:HIT000244592"
/organism="Homo sapiens"
/map="1p36"
/mol_type="mRNA"
/tissue_type="bone marrow"
/db_xref="taxon:9606"
CDS 273..2648
/gene="h6PD"
/product="glucose 1-dehydrogenase"
/EC_number="1.1.1.47"
/db_xref="GOA:O95479"
/db_xref="H-InvDB:HIT000244592.13"
/db_xref="HGNC:HGNC:4795"
/db_xref="InterPro:IPR001282"
/db_xref="InterPro:IPR005900"
/db_xref="InterPro:IPR006148"
/db_xref="InterPro:IPR019796"
/db_xref="InterPro:IPR022674"
/db_xref="InterPro:IPR022675"
/db_xref="InterPro:IPR036291"
/db_xref="InterPro:IPR037171"
/db_xref="UniProtKB/Swiss-Prot:O95479"
/protein_id="CAA10071.1"
/translation="MWNMLIVAMCLALLGCLQAQELQGHVSIILLGATGDLAKKYLWQ
GLFQLYLDEAGRGHSFSFHGAALTAPKQGQELMAKALESLSCPKDMAPSHCAEHKDQF
LQLSQYRQLKTAEDYQALNKDIEAQLQHAGLREAGRIFYFSVPPFAYEDIARNINSSC
RPGPGAWLRVVLEKPFGHDHFSAQQLATELGTFFQEEEMYRVDHYLGKQAVAQILPFR
DQNRKALDGLWNRHHVERVEIIMKETVDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVA
MELPHNVSSAEAVLRHKLQVFQALRGLQRGSAVVGQYQSYSEQVRRELQKPDSFHSLT
PTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYARILFKNQACCVQSEKHWAAAQSQ
CLPRQLVFHIGHGDLGSPAVLVSRNLFRPSLPSSWKEMEGPPGLRLFGSPLSDYYAYS
PVRERDAHSVLLSHIFHGRKNFFITTENLLASWNFWTPLLESLAHKAPRLYPGGAENG
RLLDFEFSSGRLFFSQQQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAWSEELISK
LANDIEATAVRAVRRFGQFHLALSGGSSPVALFQQLATAHYGFPWAHTHLWLVDERCV
PLSDPESNFQGLQAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVA
NSSFDLVLLGMGADGHTASLFPQSPTGLDGEQLVVLTTSPSQPHRRMSLSLPLINRAK
KVAVLVMGRMKREITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG"
BASE COUNT 506 a 939 c 886 g 522 t
ORIGIN
1 tgaggcctga ggcctggggc gggtggcggc cgggctggcc ttggcctcgc gccttcccct
61 gcggccgccg cgggctccgc gggcggtatc ggagtgtcgt gcggcgcgtg gccgcgtgac
121 acgcgcactt gtcggagtga cgggccctgc ggaagaggag gtgcggccca gggcgcaggg
181 gagccctcgg gagcgggccc ggccctcagc gccgccccgg ccgtgtcccg gaggagcggc
241 ctgcgccgcc gcgcgagagg aagcacccag gcatgtggaa tatgctcata gtggcgatgt
301 gcttggccct tctgggctgc ctgcaagccc aggagctcca gggacatgtc tccataatcc
361 tgctgggagc aactggggac ctggctaaga agtacttatg gcagggactg ttccagctgt
421 acctggatga agcggggagg ggtcacagtt ttagcttcca tggagctgct ctgacagccc
481 ccaagcaggg tcaagagctc atggccaagg ccctggaatc cctctcctgc cccaaggaca
541 tggcacccag tcactgtgca gagcacaagg atcagttcct gcagctgagc cagtaccgcc
601 aactgaagac ggccgaggac tatcaggccc tgaacaagga catcgaggca cagctccagc
661 acgcaggcct ccgggaggct ggcaggatct tctacttctc agtgccaccc ttcgcctatg
721 aagacattgc ccgcaacatc aacagtagct gccggccagg cccgggcgcc tggctgcggg
781 ttgtccttga gaaacccttt ggccatgacc acttctcagc ccagcagctg gccacagaac
841 tcgggacctt tttccaggag gaggagatgt accgggtgga ccattactta ggcaagcagg
901 ctgtggcgca gatcctgcct ttccgagacc agaaccgcaa ggctttggac ggcctctgga
961 accggcacca tgtggagcgg gtggagatca tcatgaaaga gaccgtggat gctgaaggcc
1021 gcaccagctt ctatgaggag tacggtgtca ttcgcgacgt cctccagaac catctgacgg
1081 aggtcctcac cctcgtggcc atggagctgc cccacaatgt cagcagtgcg gaggctgtgc
1141 tgcggcacaa gcttcaggtc ttccaggcgc tgcggggcct gcagaggggc agtgccgtcg
1201 tgggccagta ccagtcttac agtgagcagg tgcgcagaga gctgcagaag ccagacagct
1261 tccacagcct gacgccgacc ttcgcaggtg tcctagtgca cattgacaac cttcgctggg
1321 agggcgtgcc tttcatcctg atgtctggca aagccttgga cgagagagtg ggctacgctc
1381 ggatcttgtt caagaaccag gcctgctgtg tgcagagcga aaagcactgg gccgcggcgc
1441 agagccagtg cctgccccgg cagctcgtct tccacatcgg ccatggcgac ctgggcagcc
1501 ctgccgtgct ggtcagcagg aacctgttca ggccctccct gccctccagc tggaaggaaa
1561 tggagggacc acctgggctc cgccttttcg gcagccctct gtccgattac tacgcctaca
1621 gccctgtgcg ggagcgggac gcccactccg tcctcttatc ccatatcttc catggccgga
1681 agaatttctt catcaccaca gagaacttgc tggcctcctg gaacttctgg acccctctgc
1741 tggagagcct ggcccataag gccccacgcc tctaccctgg aggagctgag aatggccgtc
1801 tgttggactt tgagttcagt agcggccggt tgttcttttc ccagcagcag ccggagcagc
1861 tggtgccagg gccagggccg gccccaatgc ccagtgactt ccaggtcctc agggccaagt
1921 accgagagag cccgctggtc tccgcctggt ccgaggagct gatctctaag ctggctaatg
1981 acatcgaggc caccgctgtg cgagccgtgc ggcgctttgg ccagttccac ctggcactgt
2041 cggggggctc gagccccgtg gccctgttcc agcagctggc cacggcgcac tatggcttcc
2101 cctgggccca cacgcacctg tggctggttg acgagcgctg cgtcccactc tcagacccgg
2161 agtccaactt ccagggcctg caggcccacc tgctgcagca cgtccggatc ccctactaca
2221 acatccaccc catgcctgtg cacctgcagc agcggctctg cgccgaggag gaccagggcg
2281 cccagatcta tgccagggag atctcagccc tggtggccaa cagcagcttc gacctggtgc
2341 tgctgggcat gggtgccgac gggcacacag cctccctctt cccacagtca cccactggcc
2401 tggatggcga gcagctggtc gtgctgacca cgagcccctc ccagccacac cgccgcatga
2461 gccttagcct gcctctcatc aaccgcgcca agaaggtggc agtcctggtc atgggcagga
2521 tgaagcgtga gatcaccacg ctggtgagcc gggtgggcca tgagcccaag aagtggccca
2581 tctcgggtgt cctgccgcac tccggccagc tggtgtggta catggactac gacgccttcc
2641 tgggatgagg gcgcctgtgc cccttgcccg cttcgctcct gtgctttcct tcgcccgtgt
2701 cttccctccc ttctcggccc cgccacctgc ccagcgtgcc ctggctctcc agaaccttct
2761 atcccacagt caggccccag agagggcagg acaagccttg tcccgatgcc tttgaccggc
2821 agctctgtgt attggtggat agatgcagaa aca
//