LOCUS AJ012370 3152 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for NAALADase II protein.
ACCESSION AJ012370
VERSION AJ012370.1
KEYWORDS naaladase II gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3152)
AUTHORS Pangalos M.N.
JOURNAL Submitted (02-NOV-1998) to the INSDC. Pangalos M.N., Biotechnology,
Janssen Pharmaceutica, 30 Turnhoutseweg, 2340 Beerse, BELGIUM.
REFERENCE 2
AUTHORS Pangalos M.N., Neefs J.M., Somers M., Verhasselt P., Bekkers M.,
van der Helm L., Fraiponts E., Ashton D., Gordon R.D.
TITLE Isolation and expression of novel human glutamate carboxypeptidases
with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl
peptidase IV activity
JOURNAL J Biol Chem 274(13), 8470-8483(1999).
PUBMED 10085079
FEATURES Location/Qualifiers
source 1..3152
/db_xref="H-InvDB:HIT000244563"
/organism="Homo sapiens"
/chromosome="11"
/map="11q14.3-q21"
/mol_type="mRNA"
/tissue_type="lung carcinoma"
/db_xref="taxon:9606"
CDS 46..2268
/gene="naaladase II"
/product="NAALADase II protein"
/function="peptidase"
/db_xref="GOA:Q9Y3Q0"
/db_xref="H-InvDB:HIT000244563.13"
/db_xref="HGNC:HGNC:14526"
/db_xref="InterPro:IPR003137"
/db_xref="InterPro:IPR007365"
/db_xref="InterPro:IPR007484"
/db_xref="InterPro:IPR036757"
/db_xref="InterPro:IPR039373"
/db_xref="PDB:3FEC"
/db_xref="PDB:3FED"
/db_xref="PDB:3FEE"
/db_xref="PDB:3FF3"
/db_xref="UniProtKB/Swiss-Prot:Q9Y3Q0"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB39967.1"
/translation="MAESRGRLYLWMCLAAALASFLMGFMVGWFIKPLKETTTSVRYH
QSIRWKLVSEMKAENIKSFLRSFTKLPHLAGTEQNFLLAKKIQTQWKKFGLDSAKLVH
YDVLLSYPNETNANYISIVDEHETEIFKTSYLEPPPDGYENVTNIVPPYNAFSAQGMP
EGDLVYVNYARTEDFFKLEREMGINCTGKIVIARYGKIFRGNKVKNAMLAGAIGIILY
SDPADYFAPEVQPYPKGWNLPGTAAQRGNVLNLNGAGDPLTPGYPAKEYTFRLDVEEG
VGIPRIPVHPIGYNDAEILLRYLGGIAPPDKSWKGALNVSYSIGPGFTGSDSFRKVRM
HVYNINKITRIYNVVGTIRGSVEPDRYVILGGHRDSWVFGAIDPTSGVAVLQEIARSF
GKLMSKGWRPRRTIIFASWDAEEFGLLGSTEWAEENVKILQERSIAYINSDSSIEGNY
TLRVDCTPLLYQLVYKLTKEIPSPDDGFESKSLYESWLEKDPSPENKNLPRINKLGSG
SDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYETFELVEKFYDPTFKKQLSV
AQLRGALVYELVDSKIIPFNIQDYAEALKNYAASIYNLSKKHDQQLTDHGVSFDSLFS
AVKNFSEAASDFHKRLIQVDLNNPIAVRMMNDQLMLLERAFIDPLGLPGKLFYRHIIF
APSSHNKYAGESFPGIYDAIFDIENKANSRLAWKEVKKHISIAAFTIQAAAGTLKEVL
"
BASE COUNT 1046 a 570 c 645 g 891 t
ORIGIN
1 gctcgcgaat gtagcaggcg ccccaagctc ggtcctcaag aagccatggc ggaatccagg
61 ggccgtctgt acctttggat gtgcttggct gctgcgctgg catctttcct gatgggattt
121 atggtgggct ggtttattaa gcctctcaaa gaaacaacca cttctgtgcg ctatcatcaa
181 agtatacggt ggaaactggt atccgaaatg aaagctgaaa acatcaaatc atttcttcgt
241 tcttttacaa agcttcctca tctggcagga acagaacaaa atttcttgct tgccaagaaa
301 atccaaaccc agtggaagaa atttggacta gattcagcca agttggttca ttatgatgtc
361 ctcttatctt accccaatga gacaaatgcc aactatatat cgattgtgga tgaacatgaa
421 actgagattt tcaaaacatc ataccttgaa ccaccaccag atggctatga gaatgttaca
481 aatattgtgc caccatataa tgctttctca gcccaaggca tgccagaggg agatcttgta
541 tatgtgaact atgctcgcac tgaagacttt ttcaaactag aaagagagat gggcatcaac
601 tgtactggga agattgttat tgcaagatat ggaaaaatct tcagaggaaa taaagttaaa
661 aatgccatgt tagcaggagc cataggaatc atcttgtact cagatccagc tgactacttt
721 gctcctgagg tacagccata tcccaaagga tggaatcttc ctggaactgc agcccagaga
781 ggaaatgtgt taaatttgaa tggtgctggt gacccactca ctccaggcta tccagcaaaa
841 gaatacactt tcagacttga tgttgaagaa ggagtgggaa tcccccgaat acctgtacat
901 cccattggat ataatgatgc agaaatatta ttacgctact tgggaggaat tgctccacca
961 gataagagtt ggaagggagc ccttaatgtg agttatagta tcggacctgg ctttacaggg
1021 agtgattctt tcaggaaggt tagaatgcat gtttataaca tcaataaaat tacaaggatt
1081 tacaatgtag ttggaactat cagaggatct gtggaacctg acaggtatgt tattctggga
1141 ggtcaccggg actcctgggt atttggagct attgacccaa ccagtggggt tgctgttttg
1201 caagaaattg cccggagttt tggaaaactg atgagtaaag gctggagacc tagaagaact
1261 atcatttttg ccagctggga tgcagaagaa tttggacttc tgggttccac agaatgggct
1321 gaggagaatg tcaaaatact ccaggagaga agcattgctt atatcaactc ggattcatct
1381 atagaaggca attatactct cagagttgac tgtactcccc ttctttacca attagtgtat
1441 aaactgacaa aagagatccc cagccctgat gatgggtttg agagtaaatc actgtatgaa
1501 agctggttgg aaaaagaccc ttcacctgaa aataaaaatt tgcctagaat caataagctg
1561 ggatctggaa gtgactttga agcttatttt cagagacttg gaattgcttc aggcagagcc
1621 cgttacacta agaataagaa aacagataag tacagcagct acccagtgta ccacacaatt
1681 tatgagacat ttgaattggt agagaaattt tatgacccca catttaaaaa acaactttct
1741 gtggctcaat tacgaggagc actggtatat gagcttgtgg attctaaaat cattcctttt
1801 aatattcaag actatgcaga agctttgaaa aactatgcag caagtatcta taatctatct
1861 aagaaacatg atcaacaatt aacagaccat ggagtatcat ttgactcctt attttctgct
1921 gtgaaaaact tctcagaggc tgcttcagat tttcataaac gacttataca agttgatctt
1981 aacaatccca ttgcagtgag aatgatgaat gaccaactga tgctcctgga aagagcattc
2041 atcgatcctc ttggtttacc aggaaagctg ttctataggc acatcatatt tgctccaagt
2101 agccacaaca aatatgctgg agaatcattt cctggaatct atgatgctat ctttgatatt
2161 gaaaataaag ccaactctcg tttggcctgg aaagaagtaa agaaacatat ttctattgca
2221 gcttttacaa ttcaagcagc agcaggaact ctgaaagaag tattatagaa ggtctcaagt
2281 ggctagccat taaaggtgtt gctaaaagtc tgaggataaa attcaccttt ctgataactt
2341 atgaagccag ggtgttctaa actcttttca tgtcatgttt tgattatagg ctttggtctt
2401 ttcatctgca aagccttttt tttttttgct ctttaaaagt taataattat attagcaaag
2461 tgttaatcta atgaagtaaa aaactcctgt gtggcagaaa gtaaaagaaa attccctaaa
2521 ttatagcaag gaacatgaat tctcagacat tgtgagtgtg ggaatgtaaa atggtaaaat
2581 cacttttgaa aacagtttgg cagtttccta taaagttaaa catacacttt tactttagga
2641 ctccagaatt ccacttctag ttatttattc aagagaagga aaaacaatga tcacagcaat
2701 acttgtatgc atgttcattg caacttaaaa gcgtaaaaac cccaaatgtc catccacaga
2761 cgaatgtata aactgtggta tccattacac aatagactac ttactactca gcaataaaaa
2821 tgaagtaact ttcaataaat gcaatattat tggcagacat tgttgaagga aaaaagccag
2881 acaaacaact acataaaata tgtttctatt tagatgaagt ggcaaactaa tctgtagtgt
2941 taaaaattag attagtgatt gcctgggcca agtggcaggt tggggaggat ggctgcaaag
3001 aagtatgagg aaactttctc caatagatga gaattttccg tatcttgatc tgagtggcaa
3061 attgtaaact taaaatatat ataaaattta ttgaaagaaa attaagcctc aataaacgtg
3121 attataaaaa aaaaaaaaaa aagggcggcc gc
//