LOCUS AJ012159 5551 bp DNA linear HUM 15-APR-2005
DEFINITION Homo sapiens 5T4 oncofetal trophoblast glycoprotein gene.
ACCESSION AJ012159
VERSION AJ012159.1
KEYWORDS 5T4 gene; 5T4 oncofetal trophoblast glycoprotein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5551)
AUTHORS Myers K.A.
JOURNAL Submitted (23-OCT-1998) to the INSDC. Myers K.A., CRC Immunology
Group, Paterson Institute for Cancer Research, Christie Hospital,
Wilmslow Road, Manchester, M20 9BX, UK.
REFERENCE 2
AUTHORS King K.W., Sheppard F.C., Westwater C., Stern P.L., Myers K.A.
TITLE Organisation of the mouse and human 5T4 oncofoetal leucine-rich
glycoprotein genes and expression in foetal and adult murine
tissues
JOURNAL Biochim. Biophys. Acta 1445(3), 257-270(1999).
PUBMED 10366710
FEATURES Location/Qualifiers
source 1..5551
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
misc_binding 2698..2703
/bound_moiety="Sp1"
misc_binding 2704..2709
/bound_moiety="Sp1"
exon 2716..2800
/gene="5T4"
/experiment="experimental evidence, no additional details
recorded"
intron 2801..3092
/gene="5T4"
/experiment="experimental evidence, no additional details
recorded"
exon 3093..5400
/gene="5T4"
/experiment="experimental evidence, no additional details
recorded"
sig_peptide 3431..3516
/gene="5T4"
CDS 3431..4693
/gene="5T4"
/product="5T4 oncofetal trophoblast glycoprotein"
/db_xref="GOA:Q13641"
/db_xref="HGNC:HGNC:12004"
/db_xref="InterPro:IPR000372"
/db_xref="InterPro:IPR000483"
/db_xref="InterPro:IPR001611"
/db_xref="InterPro:IPR003591"
/db_xref="InterPro:IPR032675"
/db_xref="PDB:4CNC"
/db_xref="PDB:4CNM"
/db_xref="UniProtKB/Swiss-Prot:Q13641"
/protein_id="CAA09930.1"
/translation="MPGGCSRGPAAGDGRLRLARLALVLLGWVSSSSPTSSASSFSSS
APFLASAVSAQPPLPDQCPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQ
LAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPF
AFSGSNASVSAPSPLVELILNHIVPPEDERQNRSFEGMVVAALLAGRALQGLRRLELA
SNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNG
TLAELQGLPHIRVFLDNNPWVCDCHMADMVTWLKETEVVQGKDRLTCAYPEKMRNRVL
LELNSADLDCDPILPPSLQTSYVFLGIVLALIGAIFLLVLYLNRKGIKKWMHNIRDAC
RDHMEGYHYRYEINADPRLTNLSSNSDV"
mat_peptide 3517..4690
/gene="5T4"
/product="5T4 oncofetal trophoblast glycoprotein"
regulatory 5331..5336
/gene="5T4"
/regulatory_class="polyA_signal_sequence"
regulatory 5380..5385
/gene="5T4"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1309 a 1427 c 1434 g 1379 t
ORIGIN
1 ttttcatgga aatatcttca aatttcatta gtggtcctat tatagaagac acacagcagg
61 caagtgtcag agctagaaat gaccctaaat ttctgggtcc ctattcagca gccataagca
121 attgccagct gcaggaaggt ggaggcagaa gaagtaaaaa gggaacaaga ggtgaggttt
181 acgttctgcc taagtggaac agagtagaac tttgcacaaa ctccttaatc ttgcctagag
241 gcagaatgtg ggatgtacta tatgggaggc aggcaaatct gggcctggtt cccacctcca
301 tcactcattt gaacaagtta tgtaatttat ttttgcgtca attttcttgt ctgtaaaact
361 ggagtgagag gacctaactt gagtaccgaa gtgaagagtc aatgagataa tatctgtgat
421 cagcacagtg cttggcaagt ggaagacact cagtcaagct aacttaaagc cccagttttt
481 tcatttgtac aacagaacaa caacaataat agcaacaagc aataatacta acaatattta
541 tcttgcctct gagttgtctt gaaaatcaga tgagtatata tattatgttt ctaaattcta
601 aagtgtatct cactctccta acaaagcagt tggtcttcag atcaggacca gagttaatac
661 catgccagag cattattaca ggttttttcc aatgagtaat taattttatt tttaaactta
721 tcatacagta aaattgactc ttttggttta caaagttcta tgagttatag cacgttgtat
781 aggtttatgt aaccaccacc acaatccgga tacagaacat gactacagct ttagagattc
841 tttttcaaag tgttttacat tcatgttgca aaacactttt aaaaataaga aaagagatgt
901 agataaacgt gctgaagatg caaattaatg aaaccagctt ttgtgcacaa atctctgcag
961 tttccagtgt tttcagcttt tgtctgagcc atttttgctg tcggctttgc agactatctc
1021 tttctataaa agtaatcagg cgtccgttgg agagttgggt ctttcttcac attaaaggca
1081 catgtcccag gcacaagcct caggatcctt atttgatctt ttttaatacg accaggtctt
1141 aaatttccga accatgtttt ccctaattgc cattttctct ctaaaatgaa gaagcctgga
1201 agaaccttct tatcccttcg gggaaattat ttaattggga caaaggggat gtggagttac
1261 agagagcaac gatagggctt tcaggaaccc aaaacctgtc tggtataata acagatcctt
1321 ccggtaacca accattcaat ttgtccctct cccccaaccc catcctctcc atcaccatct
1381 gccagatggc cccctgggac caatcgactt tgaaaccaaa cttctctccc aggtcagctc
1441 ctgcaatccc cactcctcgt cccttggagc tttctccaca gaagtgactt gacacaccgc
1501 gctacatctg gggagggggg cgggtccgct ttccgggaga ctcaagtctt tgctatttgc
1561 cttttgtttc tgggatgcct ttggctgcct ttctcttcca tctgctttta attttggtaa
1621 gagaaaagct aatgaatcag gaatgaatct cctctccact aatctttwtg ttttctttct
1681 ctctctctct ctcttagagt tggcgcgctc tcttcacgag ttccatcact acccaagaag
1741 tgagggggcg ggggggacag gcgggaagnc attaattaca cctaaatctg aagtttgcgg
1801 cctcaagtac cactttgatg gggagagctt ctgaagcttc catacaacct gccgtgcctt
1861 tgctgctgcc gcagtagatt ttcagctcat ttctttctgc tgctgcttcg cgctgctctg
1921 tcatgcctaa atctatctcg tcactgccaa aggtgcctga atcagggtga attccacgag
1981 attcaccagc ggttttgctc cagtccaagg taaatacagt atgcaaaatg aggaaccacc
2041 caaggatgtc ggggaggggg gagagaaagg gattccctca ccttttccgg cacattcctc
2101 gttaatttcc accaggagga ggcgcgcagc ccagctcccc tagtctctct tcttaaatcc
2161 ccctacctac ggctgccgag gttggccgcg cgtcgggagt ctccccgaca gtcctggccc
2221 tcccccgccc cccgggttgg tttttcccag ctgcggaggt tgggaggttg ggccaggggc
2281 tggggtgcga agagagtcgg cgcccgcaac gcggagccgg gaagtcgtcg ctactctggt
2341 ggaactcaga gttggttctg gaggcggcgg acgcggaggt gagcagtggg agcccgcggc
2401 ctgggagaga cccgggaggc gtcgttgggg cccctcccca tcctcgggtg gagagtaggg
2461 ttggttcggg ttgccactgt accccgagtc ccactgctgc tttgttccca gactctcccc
2521 tcctctttgg agatgacttg aacccctttg agatccgagg ggctggcggg gcgcgggctg
2581 gggggcgaca gttgtagctc cacttcctgc taatgcgaga aggtacaaaa agagatcaaa
2641 aagtcctgta acctgaaact tccctcgcat cctaaccggg accgggtgga gaggtctggg
2701 cgggggcgga gacacccgga ggccgacctt ccgccgaggc ggtgcaggaa ggaacgggag
2761 agggagaagt ttggtaggga aggaattggg gattaagcgg taagttagac gcgggagacg
2821 atctcctcgg gaaaggcgga gggcgggagg ccggtcgggt ttatttagtg tgggccaggg
2881 aagaaggaag actttgcggt ctgggtgtcg gatgcgcgtc cccctccgga gtaaaagtga
2941 ccggaggggt tggggaggcg aggccggggc gggcttttgg aaggaggtct ctgggacaga
3001 ctggagacga ctagactcga aaaggccggt ttttgcactc cggaagccgc ggcagccacc
3061 gctgttcacg cctctctcct gcttgtccca ggtccctcag aggatccagc gaggggtgcc
3121 aacaagaggc gaagaggtgg caccagggcg gcggcaggaa gaggagcggg agcaggagcg
3181 cggagcggag cgtcccgacc cgccgtgcgt actttctgga gggaaggggc gggggaatcg
3241 gcccctgagg gaagcgcccg gtggcgaggg ggttagccaa gttccggctg cggcgccact
3301 ccctcggttc cacgagagga aagttttttt tttccagacg cttccgccgg ctcgcgccct
3361 ccgggcccag cctcccgagc cttcggagcg ggcgccgtcc cagcccagct ccggggaaac
3421 gcgagccgcg atgcctgggg ggtgctcccg gggccccgcc gccggggacg ggcgtctgcg
3481 gctggcgcga ctagcgctgg tactcctggg ctgggtctcc tcgtcttctc ccacctcctc
3541 ggcatcctcc ttctcctcct cggcgccgtt cctggcttcc gccgtgtccg cccagccccc
3601 gctgccggac cagtgccccg cgctgtgcga gtgctccgag gcagcgcgca cagtcaagtg
3661 cgttaaccgc aatctgaccg aggtgcccac ggacctgccc gcctacgtgc gcaacctctt
3721 ccttaccggc aaccagctgg ccgtgctccc tgccggcgcc ttcgcccgcc ggccgccgct
3781 ggcggagctg gccgcgctca acctcagcgg cagccgcctg gacgaggtgc gcgcgggcgc
3841 cttcgagcat ctgcccagcc tgcgccagct cgacctcagc cacaacccac tggccgacct
3901 cagtcccttc gctttctcgg gcagcaatgc cagcgtctcg gcccccagtc cccttgtgga
3961 actgatcctg aaccacatcg tgccccctga agatgagcgg cagaaccgga gcttcgaggg
4021 catggtggtg gcggccctgc tggcgggccg tgcactgcag gggctccgcc gcttggagct
4081 ggccagcaac cacttccttt acctgccgcg ggatgtgctg gcccaactgc ccagcctcag
4141 gcacctggac ttaagtaata attcgctggt gagcctgacc tacgtgtcct tccgcaacct
4201 gacacatcta gaaagcctcc acctggagga caatgccctc aaggtccttc acaatggcac
4261 cctggctgag ttgcaaggtc taccccacat tagggttttc ctggacaaca atccctgggt
4321 ctgcgactgc cacatggcag acatggtgac ctggctcaag gaaacagagg tagtgcaggg
4381 caaagaccgg ctcacctgtg catatccgga aaaaatgagg aatcgggtcc tcttggaact
4441 caacagtgct gacctggact gtgacccgat tcttccccca tccctgcaaa cctcttatgt
4501 cttcctgggt attgttttag ccctgatagg cgctattttc ctcctggttt tgtatttgaa
4561 ccgcaagggg ataaaaaagt ggatgcataa catcagagat gcctgcaggg atcacatgga
4621 agggtatcat tacagatatg aaatcaatgc ggaccccaga ttaacaaacc tcagttctaa
4681 ctcggatgtc tgagaaatat tagaggacag accaaggaca actctgcatg agatgtagac
4741 ttaagcttta tccctactag gcttgctcca ctttcatcct ccactataga tacaacggac
4801 tttgactaaa agcagtgaag gggatttgct tccttgttat gtaaagtttc tcggtgtgtt
4861 ctgttaatgt aagacgatga acagttgtgt atagtgtttt accctcttct ttttcttgga
4921 actcctcaac acgtatggag ggatttttca ggtttcagca tgaacatggg cttcttgctg
4981 tctgtctctc tctcagtaca gttcaaggtg tagcaagtgt acccacacag atagcattca
5041 acaaaagctg cctcaacttt ttcgagaaaa atactttatt cataaatatc agttttattc
5101 tcatgtacct aagttgtgga gaaaataatt gcatcctata aactgcctgc agacgttagc
5161 aggctcttca aaataactcc atggtgcaca ggagcacctg catccaagag catgcttaca
5221 ttttactgtt ctgcatatta caaaaaataa cttgcaactt cataacttct ttgacaaagt
5281 aaattacttt tttgattgca gtttatatga aaatgtactg attttttttt aataaactgc
5341 atcgagatcc aaccgactga attgttaaaa aaaaaaaaaa ataaacattg ttaaaacaat
5401 tacagtgtgt gcaagtttgc tttgaaaaaa ggatgaaggg caggagtatt caatggtctt
5461 ggttccgatg ataattatta cttaacatag ctgagaatca aactgtagca atgtctaata
5521 taaatagact tgggagatcg tttcgaaatg g
//