LOCUS AJ011812 3736 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for transcription factor NRF, partial.
ACCESSION AJ011812
VERSION AJ011812.2
KEYWORDS NF-kappa-B; nrf gene; transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Nourbakhsh M.
JOURNAL Submitted (06-OCT-1998) to the INSDC. Nourbakhsh M., RDIF, GBF
National Research Center for Biotechnology, Mascheroder Weg 1,
38124 Braunschweig, 38124, GERMANY.
REMARK Revised by [3]
REFERENCE 2
AUTHORS Nourbakhsh M., Hauser H.
TITLE Constitutive silencing of IFN-beta promoter is mediated by NRF
(NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB
JOURNAL EMBO J. 18(22), 6415-6425(1999).
PUBMED 10562553
REFERENCE 3 (bases 1 to 3736)
AUTHORS Nourbakhsh M.
JOURNAL Submitted (30-MAR-2000) to the INSDC. Nourbakhsh M., RDIF, GBF
National Research Center for Biotechnology, Mascheroder Weg 1,
38124 Braunschweig, 38124, GERMANY.
FEATURES Location/Qualifiers
source 1..3736
/db_xref="H-InvDB:HIT000244543"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_line="HeLa S3"
/cell_type="epitheloid carcinoma"
/tissue_type="cervix"
/db_xref="taxon:9606"
5'UTR <1..653
/gene="nrf"
CDS 654..1820
/codon_start=1
/gene="nrf"
/product="transcription factor NRF"
/function="NF-kappa-B repression"
/db_xref="GOA:O15226"
/db_xref="H-InvDB:HIT000244543.14"
/db_xref="HGNC:HGNC:19374"
/db_xref="InterPro:IPR000467"
/db_xref="InterPro:IPR001374"
/db_xref="InterPro:IPR014720"
/db_xref="InterPro:IPR034071"
/db_xref="InterPro:IPR036867"
/db_xref="UniProtKB/Swiss-Prot:O15226"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAB56459.1"
/translation="MEKILQMAEGIDIGEMPSYDLVLSKPSKGQKRHLSTCDGQNPPK
KQAGSKFHARPRFEPVHFVASSSKDEGQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQ
DSFSIQDGNSQYCDSSGFILTKDQPVTANMYFDSGNPAPSTTSQQANSQSTPEPSPSQ
TFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIY
APLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQK
RIEVRVVRRKFKHTFGEDLVVCQIGMSSYEFPPALKPPEDLVVLGKDASGQPIFNASA
KHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRSSSVFTRSLLS"
3'UTR 1821..>3736
/gene="nrf"
BASE COUNT 1212 a 684 c 754 g 1086 t
ORIGIN
1 cagagtaatg acatggttcc ttccatcctc caaaggtgac caataatagt ttgtaagtat
61 cattatgaac taatgaattt tcaacatatt tgatatattt caatccattg ccatcattgt
121 tcttatcgat atttgagttg gctcactttg ccagtaagag tctattcaaa ttggcttctg
181 agtccatttg acacaacacc tttgatcttt gacagtttcc ttggttttag gtgctagatg
241 atttctcagg ctcaccttag acatttcctg ccacagactt agaatcagcc atttctctaa
301 ggaccctgat tccatttcat gagaaatgat agagaccaca atcaaaacaa gtcatgaatt
361 tatactgata ttttcaattc aaattaaaga tgaggttttt gctaaatttt tttgagttta
421 tatttgtatg tcttatgctg aaaaatcttg tttcctaatt agtaacataa ttattcattt
481 gatgggtaaa tattttaggg ccgattcttt ggttttatag ccaagatacc ctgttgataa
541 agtcttgtgg gagcaattat aagactggct tattttgaag ctttttaaaa aagacatcct
601 tacctgtttt aactgtagat tatattaact taaataggta cagcccacgc ttgatggaaa
661 aaattctcca aatggctgaa ggtattgata ttggggagat gccttcatat gatctggtgc
721 tgtccaaacc ttccaaaggt caaaaacgcc acctctcaac atgtgatggt caaaatcctc
781 ctaaaaagca agccggttcc aaattccatg cgagacctcg ttttgagcct gtacattttg
841 tagctagtag ttcaaaagat gaaggacagg aagatcctta tggccctcaa acaaaagagg
901 taaatgaaca aacacatttt gccagcatgc caagagacat ctaccaagat tatactcaag
961 actctttcag tatacaagat gggaattctc agtattgtga ttcatcagga ttcattctca
1021 caaaagacca gcctgtaaca gccaacatgt attttgacag tgggaaccct gccccaagca
1081 ccacatcaca gcaggcaaac tctcagtcaa ctcctgagcc ttcaccatca cagacatttc
1141 ccgagtctgt ggtagccgag aagcagtatt ttattgaaaa attaacggcg acaatctgga
1201 agaacctttc taatccagaa atgacttctg gatctgataa aattaattat acatatatgt
1261 taactcgttg tattcaggcg tgtaagacaa atcctgagta tatatatgct cctttaaagg
1321 aaattcctcc tgccgacatc cccaaaaata aaaaacttct aactgatggc tatgcttgtg
1381 aagttagatg ccaaaatatc tacttaacta caggttatgc tggcagcaag aatgggtcca
1441 gggatcgagc tacagagcta gctgtaaaac tcttgcagaa acgtattgaa gttagagttg
1501 tccggcggaa attcaagcat acatttggag aggacctcgt ggtgtgtcag attggcatgt
1561 cctcctatga atttcctcca gctctgaagc caccagaaga cctggtggtg ctgggtaaag
1621 atgcttccgg gcagccaatt tttaatgctt ctgccaaaca ctggaccaat tttgtcatta
1681 cagaaaatgc aaatgatgca attggtatcc ttaacaattc tgcctcattc aacaagatgt
1741 caattgaata caaatatgag atgatgccaa atcgcacatg gcgttcgtcg agtgttttta
1801 caagatcact gcttagctga aggttatgga accaagaaaa caagtaaaca tgcagctgcc
1861 gacgagtttg aaaattcttc aaaaacacag cccacttatc catctgtcaa aagttcacaa
1921 tgccatacag gctcttcacc cagaggatct ggaaagaaga aagatataaa ggctctgtag
1981 tttatgagaa ttcttcaaat cccgtgtgca cgctgaacga cacagctcag tttaaccgaa
2041 tgacagttga gtatgtctat gaaaggatga caggcctccg ctggaaatgc aaagtgattc
2101 tagagagtga agtaattgca gaagcagttg gggtgaagaa aactgtcaaa tataagctgc
2161 tggggaagct gtgaaaaccc tcaaaaagac ccagcaactg tcattaacaa cttgaagaaa
2221 ggagctgttg aagatgtgat ttcaagaaat gaaattcagg gccgctcagc agaggaggct
2281 tacaaacagc aaatcaaaga agataatatt ggaaatcagc tgctgagaaa gatgggttgg
2341 actggtggtg gtttaggtaa atctggtgag ggcatacggg agcctatctc agtgaaagag
2401 cagcataacg gaagggcttg gtctggatgt agagagggtg ataaaatgcc aagagagata
2461 ttgaacagat catcagaaac tacgaaagct ccgagagcca cacagatttg actttctcta
2521 gagagctgac taatgatgaa cggaagcaaa tacatcagat tgcccagaag tatggtctta
2581 agagtaagtc tcatggggtg ggccatgata ggtacctagt ggtaggtaga aaaagacgga
2641 aggaagacct actagatcag ctcaaacagg aaggccaagt gggcattacg agcttgttat
2701 gcctcaagca aattgagatc ttactaattt attttgtaaa tgcctaatga ggtagatttt
2761 tgaattaaag aaatgctaca tgttccggtt gcagagtata ttcataagat gtctcacctt
2821 gttcatttca catagtggtt tattagatat tggaacctaa agaattctgt ccacttgtat
2881 tagcttaatc cagcagatga tattgtgcag ttactgtttg tgtctttgat attgctgtgt
2941 ccctcagatt ttagtagttt gacaagcaag aacacatatc caaatggaat tttaccctga
3001 gaaattagca ttttaaaggg catagcacag caatctgcaa caatatgtaa agttgatatt
3061 gactacaata aaaatccagt cttaattcca gatttactga aaatgtcaga tcattttgta
3121 ttaatctatt ttcatctttg tgtgaagcca gttatagaat gtttgacaat aaattgtgct
3181 gtacatgtcc ttaccaacaa atgatgtaaa actttcttaa agtaatttta gtgttattta
3241 tttataactt ctaccatgtg atttccagac tattggaagt gatttactgt atcttgtggg
3301 gatatatttt taacaaattc tactcttcac gctgagagag cactacttga gagagcagtt
3361 gaaagtttca aaaactttgg ttcaatctga agaaaggaag cttgaactgt ttgttcttgg
3421 tgccttgcag agagactcac agcaactctc cattatagct ttcacacggt ttggatgtgc
3481 agcacatcca aggcacacca cagctgtggt agagcttggt aaaagactga atacattggt
3541 gctttgatga aaaggtcagt tggctggtcc ctctctcaaa aagcttatta agcctgaaaa
3601 gccaactttg taacatattt aaaactgcta ttttcgctta tttctggaat gtaaaaaaaa
3661 aatgtataaa aagaattagt gtatgcttcc tgaataaaaa ggagccaaag ttgatcagaa
3721 aaaaaaaaaa aaaaaa
//