LOCUS AJ011701 3394 bp DNA linear HUM 14-NOV-2006
DEFINITION Homo sapiens TRHR gene promoter and exons 1-2, partial.
ACCESSION AJ011701
VERSION AJ011701.1
KEYWORDS TRHR gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3394)
AUTHORS Matre V.
JOURNAL Submitted (02-OCT-1998) to the INSDC. Matre V., Biochemistry,
University of Oslo, PB 1041 Blindern, 0316 Oslo, NORWAY.
REFERENCE 2
AUTHORS Matre V., Hovring P.I., Orstavik S., Frengen E., Rian E.,
Velickovic Z., Murray-McIntosh R.P., Gautvik K.M.
TITLE Structural and functional organization of the gene encoding the
human thyrotropin-releasing hormone receptor.
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..3394
/db_xref="H-InvDB:HIT000384068"
/organism="Homo sapiens"
/mol_type="genomic DNA"
/tissue_type="Human placenta"
/db_xref="taxon:9606"
regulatory 1..1690
/gene="TRHR"
/regulatory_class="promoter"
mRNA join(<1691..1946,2488..>3364)
/gene="TRHR"
exon 1691..1946
/gene="TRHR"
/number=1
intron 1947..2487
/gene="TRHR"
/number=1
exon 2488..3364
/gene="TRHR"
/number=2
CDS 2576..>3364
/gene="TRHR"
/product="thyrotropin-releasing hormone receptor"
/db_xref="GOA:P34981"
/db_xref="H-InvDB:HIT000384068.7"
/db_xref="HGNC:HGNC:12299"
/db_xref="InterPro:IPR000276"
/db_xref="InterPro:IPR002120"
/db_xref="InterPro:IPR017452"
/db_xref="UniProtKB/Swiss-Prot:P34981"
/protein_id="CAA09746.1"
/translation="MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNI
MVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCIT
YLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLW
FFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARIL
FLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQ"
BASE COUNT 965 a 683 c 743 g 1003 t
ORIGIN
1 ctgtctactc aaaatagact cttccattga cctcttctag aggttttggt gttttttgtt
61 tgtttgttgt tgttgttgtt gtttgggttt ttttggtttt tgtttttttg agacagagtt
121 ttgctcttgt cgcccaggct ggagtacaat ggcgtgatct cggcttactg caacttctgc
181 ctcccaggtt caagagattc tcctgcctca ggctccccag tagttatgat tacagacgtg
241 tgccaccaca cccagctaat ttttgtattt ttagcagaga cggagttttg ccatgttggc
301 caggctggtc tcaaactcct gacctctggt gatctgccca cctcggcctc ccaaagtgct
361 ggtgtgatca caagcatgag ccaccgtgcc cagcctagag gtctattctt aatccaccag
421 ttaccttaca ggaaatttag ctaagggtat ttttcattgt cagttaataa aataaaagtg
481 gagaagcatc agcatttgat gtattcagtt ggtatcttga gaaaagatac atgttttctg
541 agcttccatt aaaaaaatag atttaagaca aggcatagtg cctcacacct gtaatcccag
601 cactttggaa ggctgaggta ggtgggtcac ttgagcccag aagttcaaga ccagcctgtg
661 caaaataaca agaccccatc tctacaaaaa aatacaaaac ttagctgagc gtggtggtgt
721 gcacctgtag tctccgctac acaagaggct gaggtaggag gatcacttga gcccaggagg
781 tcgaggctgc agtgagctgt gatcatgcca ctgcactcca gtctgggtga cagagtgaga
841 tcctgtctca aagttaaaaa aaaaaaaaca aactgtagat ttgcccactg gctactttag
901 agaaataata atgctgaagt gtacttttct tcaaaagatg tgtctattaa ttttcatttc
961 agaggtttgg taacagaatg gcactggtat agatttttac tagatgattt ttccacctag
1021 aaataaactg agacaaaaca ttgctaggtg gttcatgtga ctggaaatcc agaggacagg
1081 tgaaggtgaa aagcacccag ggccgataga gagattctat aaagtggtcc agaaataaga
1141 gttgaaaaac ttaacagacc ctacgcagtt taaaataatt gttataagca tcagaagatt
1201 gcagctgaaa tggtttgaaa tcaactttaa ctaattttcc attcacaaaa tatgagagga
1261 ggaagccaat tgtactgatt cacttgagaa acagtacaag ggttttcata gtagagaaag
1321 aggttgattt cagctcagac agatatttca agcttcaagg gccatgtcta gactgagaag
1381 gatttgctaa ccccaaagtc ctatcaagca aggactgtaa atgtatttca gagcagctca
1441 ggtactagag tttctgcaga acttagatga taagcaacga caaagccagc tgcttctaga
1501 cccctggctt atgatttcag ctttccaaat taaagactgt ctcatcagca catttaatag
1561 taaatcctcc aagagcagaa gactctgaat cagtgaggac tgactggcat ctgtgagtgt
1621 gtgtgaatgt atgtgtgtgt gtgtgtgtgt gtctctgtgt gtgagagagc gagcgagcgt
1681 gtatgttctc attaggggac gatctatgat ttgacagcct cactgctgct gctcctgctg
1741 ctgcttctgc ttctgccgcg gctgtatggt ttgtcattag ttggaaaggg ctgtgagggt
1801 ttggagaaac tgcagtttta aagactgagc actgctaagt ggtctccctc tcaaatagag
1861 tagacaagat tttctgcaag attagaaact tggaactatt accacttcat ctacccagaa
1921 aatcaggcag cgctacagag gataaggtaa gagaagaaat tgtcctctct tgaatctgtg
1981 gggcaggggg catggggaaa tgtcatctca aaggcttgct attttatacc aaagacatct
2041 caccctctga gagcaaaaga ggcaacagct aaatttgtaa caagcttgat tattgagctt
2101 cttggctttt tcctctggta tctttttctt ctttattata cttttgccag gcatctaaga
2161 ggtgtattca tatttatttt tcagttagca gatatttagt ttttttcaac tgggcactgt
2221 ttcaaaacaa ttagttttta ctgtttctct ttccttaagc atttttctcc attaagaggg
2281 aactggtccc tcttaatgtg agctggtcaa aacagttact ccattctaca ctagagatgc
2341 aataaaagaa gttttaagaa gtacacatga gccctattcc catagaaaaa agagaagtga
2401 aaggagtgga agtgacggtt atttgtgatt gggacttgat cagaaattgt aacactgtta
2461 atgaatatgt actatgaccc ttcacagggg gatggaactg ctgcaataaa ggtgggcgct
2521 ggaaagaaga tgttttgaga agtcagtgtt tccgagaaac tttaagcttc taaagatgga
2581 aaacgagaca gtcagtgaac tgaaccaaac acagcttcag ccacgagcag tggtggcctt
2641 agaataccag gtggtcacca tcttacttgt actcattatt tgtggcctgg gtattgtagg
2701 caacatcatg gtagtcctgg ttgtcatgag aaccaagcac atgaggaccc ccacaaactg
2761 ctacctggtg agcctggcag tagctgatct catggtcttg gtggccgcag gcctccccaa
2821 cataacagac agtatctacg gttcctgggt ctatggctat gttggatgcc tctgcattac
2881 ttacctccag tatttgggaa ttaatgcatc ctcttgttca ataacagcct ttaccattga
2941 gaggtacata gcaatctgtc accccatcaa agcccagttt ctctgcacat tttccagagc
3001 caaaaagatt atcatctttg tctgggcttt cacatctctt tactgtatgc tctggttctt
3061 cttgctggat ctcaatatta gcacctacaa agatgctatt gtgatatcct gtggctacaa
3121 gatctccagg aattactact cacctattta cctaatggac tttggtgtct tttatgttgt
3181 gccaatgatc ctggctaccg tcctctatgg attcatagct agaatccttt tcttaaatcc
3241 cattccttca gatcctaaag aaaactctaa gacatggaaa aatgattcaa cccatcagaa
3301 cacaaatctg aatgtaaata cctctaatag atgtttcaac agcacagtat cttcaaggaa
3361 gcaggtaagc aaaactgaaa ctccaagtca atag
//