LOCUS AJ011414 3863 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for plexin-B1 plasma membrane receptor, truncated
splice variant (plexin-B1/SEP gene).
ACCESSION AJ011414
VERSION AJ011414.1
KEYWORDS plasma membrane receptor; plexin-B1/SEP gene; semaphorin receptor;
splice variant.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3863)
AUTHORS Tamagnone L.
JOURNAL Submitted (18-SEP-1998) to the INSDC. Tamagnone L., Molecular
Oncology, Institute for Cancer Research, University of Torino, SP
142, Candiolo, Torino, 10060, ITALY.
REFERENCE 2
AUTHORS Tamagnone L., Artigiani S., Longati P., Comoglio P.M.
TITLE The SEX/plexin receptor family
JOURNAL Unpublished.
REFERENCE 3
AUTHORS Tamagnone L., Artigiani S., Chen H., He Z., Ming G.L., Song H.L.,
Chedotal A., Winberg M.L., Goodman C.S., Poo M.M.,
Tessier-Lavigne M., Comoglio P.M.
TITLE Plexins are a large family of receptors for transmembrane,
secreted, and GPI-anchored semaphorins in vertebrates
JOURNAL Cell 99(1), 71-80(1999).
PUBMED 10520995
FEATURES Location/Qualifiers
source 1..3863
/db_xref="H-InvDB:HIT000244510"
/organism="Homo sapiens"
/chromosome="3"
/mol_type="mRNA"
/cell_line="GTL-16"
/cell_type="gastric carcinoma"
/tissue_type="epithelium"
/db_xref="taxon:9606"
CDS 1..2190
/gene="plexin-B1/SEP"
/product="plexin-B1/SEP receptor"
/function="plasma membrane receptor"
/note="extracellular domain, truncated splice variant"
/db_xref="GOA:O43157"
/db_xref="H-InvDB:HIT000244510.14"
/db_xref="HGNC:HGNC:9103"
/db_xref="InterPro:IPR001627"
/db_xref="InterPro:IPR002165"
/db_xref="InterPro:IPR002909"
/db_xref="InterPro:IPR008936"
/db_xref="InterPro:IPR013548"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR014756"
/db_xref="InterPro:IPR015943"
/db_xref="InterPro:IPR016201"
/db_xref="InterPro:IPR031148"
/db_xref="InterPro:IPR036352"
/db_xref="InterPro:IPR041019"
/db_xref="InterPro:IPR041362"
/db_xref="PDB:2JPH"
/db_xref="PDB:2OS6"
/db_xref="PDB:2R2O"
/db_xref="PDB:2REX"
/db_xref="PDB:3HM6"
/db_xref="PDB:3OL2"
/db_xref="PDB:3SU8"
/db_xref="PDB:3SUA"
/db_xref="PDB:5B4W"
/db_xref="UniProtKB/Swiss-Prot:O43157"
/protein_id="CAB56221.1"
/translation="MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTS
GTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLL
VSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGL
AGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHF
VSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLI
QAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN
RTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPL
EATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRC
SRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPGE
SYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSL
SFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQVMETQQ
SLRALPPPSSSRPASTTSMTPPGSGSWKRRPWGQAPAPVWRAFRAPR"
sig_peptide 1..90
/gene="plexin-B1/SEP"
mat_peptide 91..2185
/gene="plexin-B1/SEP"
/product="plexin-B1/SEP receptor"
/function="plasma membrane receptor"
/note="extracellular domain, truncated splice variant"
BASE COUNT 664 a 1203 c 1231 g 765 t
ORIGIN
1 atgcctgctc tgggcccagc tcttctccag gctctctggg ccgggtgggt cctcaccctc
61 cagccccttc caccaactgc attcactccc aatggcacgt atctgcagca cctggcaagg
121 gaccccacct caggcaccct ctacctgggg gctaccaact tcctgttcca gctgagccct
181 gggctgcagc tggaggccac agtgtccacc ggccctgtgc tagacagcag ggactgcctg
241 ccacctgtga tgcctgatga gtgcccccag gcccagccta ccaacaaccc gaatcagctg
301 ctcctggtga gcccaggggc cctggtggta tgcgggagcg tgcaccaggg ggtctgtgaa
361 cagcggcgcc tggggcagct cgagcagctg ctgctgcggc cagagcggcc tggggacaca
421 caatatgtgg ctgccaatga tcctgcggtc agcacggtgg ggctggtagc ccagggcttg
481 gcaggggagc ccctcctgtt tgtggggcga ggatacacca gcaggggtgt ggggggtggc
541 attccaccca tcacaacccg ggccctgtgg ccgcccgacc cccaagctgc cttctcctat
601 gaggagacag ccaagctggc agtgggccgc ctctccgagt acagccacca cttcgtgagt
661 gcctttgcac gtggggccag cgcctacttc ctgttcctgc ggcgggacct gcaggctcag
721 tctagagctt ttcgtgccta tgtatctcga gtgtgtctcc gggaccagca ctactactcc
781 tatgtggagt tgcctctggc ctgcgaaggt ggccgctacg ggctgatcca ggctgcagct
841 gtggccacgt ccagggaggt ggcgcatggg gaggtgctct ttgcagcttt ctcctcggct
901 gcacccccca ctgtgggccg gcccccatcg gcggctgctg gggcatctgg agcctctgcc
961 ctctgtgcct tccccctgga tgaggtggac cggcttgcta atcgcacgcg agatgcctgc
1021 tacacccggg agggtcgtgc tgaggatggg accgaggtgg cctacatcga gtatgatgtc
1081 aattctgact gtgcacagct gccagtggac accctggatg cttatccctg tggctcagac
1141 cacacgccca gccccatggc cagccgggtc ccgctggaag ccacaccaat tctggagtgg
1201 ccagggattc agctaacagc tgtggcagtc accatggaag atggacacac catcgctttc
1261 ctgggtgata gtcaagggca gctgcacagg gtctacttgg gcccagggag cgatggccac
1321 ccatactcca cacagagcat ccagcagggg tctgcagtga gcagagacct cacctttgat
1381 gggacctttg agcacctgta tgtcatgacc cagagcacac ttctgaaggt tcctgtggct
1441 tcctgtgctc agcacctgga ctgtgcatct tgccttgctc acagggaccc atactgtggg
1501 tggtgcgtgc tccttggcag gtgcagtcgc cgttctgagt gctcgagggg ccagggccca
1561 gagcagtggc tatggagctt ccagcctgag ctgggctgtc tgcaagtggc agccatgagt
1621 cctgccaaca tcagccgaga ggagacgagg gaggttttcc tatcagtgcc agacctgcca
1681 cccctgtggc caggggagtc atattcctgc cactttgggg aacatcagag tcctgccctg
1741 ctgactggtt ctggtgtgat gtgcccctcc ccagacccta gtgaggcccc agtgctgccg
1801 agaggagccg actacgtatc cgtgagcgtg gagctcagat ttggcgctgt tgtgatcgcc
1861 aaaacttccc tctctttcta tgactgtgtg gcggtcactg aactccgccc atctgcgcag
1921 tgccaggcct gtgtgagcag ccgctggggg tgtaactggt gtgtctggca gcacctgtgc
1981 acccacaagg cctcgtgtga tgctgggccc atggttgcaa gccatcaggt gatggagact
2041 cagcagagct tgagggccct cccgcccccc tcatcctccc gtccagcctc gactaccagt
2101 atgacacccc cgggctctgg gagctggaag aggcgacctt gggggcaagc tcctgcccct
2161 gtgtggagag cgttcagggc tccacgttga tgccggtcca tgtggagcgg gaaatccggc
2221 tgctaggcag gaacctgcac cttttccagg atggcccagg agacaatgag tgtgtgatgg
2281 agctggaggg cctcgaggtg gtggttgagg cccgggtcga gtgtgagcca cctccagata
2341 cccagtgcca tgtcacctgc cagcagcacc agctcagcta tgaggctctg cagccggagc
2401 tccgtgtggg gctgtttctg cgtcgggccg gccgtctgcg tgtggacagt gctgaggggc
2461 tgcatgtggt actgtatgac tgttccgtgg gacatggaga ctgcagccgc tgccaaactg
2521 ccatgcccca gtatggctgt gtgtggtgtg agggggagcg tccacgttgt gtgacccggg
2581 aggcctgtgg tgaggctgag gctgtggcca cccagtgccc agcgcccctc atccactcgg
2641 tggagccact gactgggcct gtagacggag gcacccgtgt caccatcagg ggctccaacc
2701 tgggccagca tgtgcaggat gtgctgggca tggtcacggt ggctggagtg ccctgtgctg
2761 tggatgccca ggagtacgag gtctccagca gcctcgtgtg catcaccggg gccagtgggg
2821 aggaggtggc cggcgccaca gcggtggagg tgccgggaag aggacgtggt gtctcagaac
2881 acgactttgc ctaccaggat ccgaaggtcc attccatctt cccggcccgc ggccccagag
2941 ctgggggcac ccgtctcacc ctgaatggct ccaagctcct gactgggcgg ctggaggaca
3001 tccgagtggt ggttggagac cagccttgtc acttgctgcc ggagcagcag tcagaacaac
3061 tgcggtgtga gaccagccca cgccccacgc ctgccacgct ccctgtggct gtgtggtttg
3121 gggccacgga gcggaggctt caacgcggac agttcaagta taccttggac cccaacatca
3181 cctctgctgg ccccaccaag agcttcctca gtggaggacg tgagatatgc gtccgtggcc
3241 agaatctgga cgtggtacag acgccaagaa tccgggtgac cgtggtctcg agaatgctgc
3301 agcccagcca ggggcttgga cggaggcgtc gcgtggtccc ggagacggca tgttcccttg
3361 gaccctcctg cagtagccag caatttgagg agccgtgcca tgtcaactcc tcccagctca
3421 tcacgtgccg cacacctgcc ctcccaggcc tgcctgagga cccctgggtc cgggtggaat
3481 ttatccttga caacctggtc tttgactttg caacactgaa ccccacacct ttctcctatg
3541 aggccgaccc caccctgcag ccactcaacc ctgaggaccc caccatgcca ttccggcaca
3601 agcctgggag tgtgttctcc gtggaggggg agaacctgga ccttgcaatg tccaaggagg
3661 aggtggtggc tatgataggg gatggcccct gtgtggtgaa gacgctgacg cggcaccacc
3721 tgtactgcga gccccccgtg gagcagcccc tgccacggca ccatgccctc cgagaggcac
3781 ctgactcttt gcctgagttc acggtgcaga tggggaactt gcgcttctcc ctgggtcacg
3841 tgcagtatga cggcgagagc cct
//