LOCUS AJ010119 3131 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for Ribosomal protein kinase B (RSK-B).
ACCESSION AJ010119
VERSION AJ010119.1
KEYWORDS ribosomal protein kinase B; rskb gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3131)
AUTHORS Lesslauer W.
JOURNAL Submitted (11-AUG-1998) to the INSDC. Lesslauer W., PRPN, F.
Hoffmann-LaRoche Ltd, Grenzacherstrasse 124, CH-4070 Basel,
SWITZERLAND.
REFERENCE 2
AUTHORS Pierrat B., Correia J.D.S., Mary J.L., Tomas-Zuber M., Lesslauer W.
TITLE RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase
under dominant control of p38alpha mitogen-activated protein kinase
(p38alphaMAPK)
JOURNAL J Biol Chem 273(45), 29661-29671(1998).
PUBMED 9792677
FEATURES Location/Qualifiers
source 1..3131
/db_xref="H-InvDB:HIT000244392"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_type="placenta"
/db_xref="taxon:9606"
CDS 66..2384
/gene="rsk-b"
/product="Ribosomal protein kinase B (RSK-B)"
/function="CREB-Kinase"
/db_xref="GOA:O75676"
/db_xref="H-InvDB:HIT000244392.14"
/db_xref="HGNC:HGNC:10433"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR000961"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR016239"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR017892"
/db_xref="InterPro:IPR037714"
/db_xref="UniProtKB/Swiss-Prot:O75676"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAA09009.1"
/translation="MGDEDDDESCAVELRITEANLTGHEEKVSVENFELLKVLGTGAY
GKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLH
YAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYR
DLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKA
VDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRL
LCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEE
FTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAA
VARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANT
QREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQ
ILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPM
QTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEI
MCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSS
PPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATA
SRRGSPAPANPGRAPVASKGAPRRANGPLPPS"
BASE COUNT 570 a 1006 c 1009 g 546 t
ORIGIN
1 ggagccgcca tgtaaccggc gccgcccgga gcccgagccg cgcgggcccc agcgacccgc
61 ccgccatggg ggacgaggac gacgatgaga gctgcgccgt ggagctgcgg atcacagaag
121 ccaacctgac cgggcacgag gagaaggtga gcgtggagaa cttcgagctg ctcaaggtgc
181 tgggcacggg agcctacggc aaggtgttcc tggtgcggaa ggcgggcggg cacgacgcgg
241 ggaagctgta cgccatgaag gtgctgcgca aggcggcgct ggtgcagcgc gccaagacgc
301 aggagcacac gcgcaccgag cgctcggtgc tggagctggt gcgccaggcg cccttcctgg
361 tcacgctgca ctacgctttc cagacggatg ccaagctgca cctcatcctg gactatgtga
421 gcggcgggga gatgttcacc cacctctacc agcgccagta cttcaaggag gctgaggtgc
481 gcgtgtatgg gggtgagatc gtgctggccc tggaacacct gcacaagctc ggcatcattt
541 accgagacct gaaactggag aatgtgctgc tggactccga gggccacatt gtcctcacgg
601 acttcgggct gagcaaggag ttcctgacgg aggagaaaga gcggaccttc tccttctgtg
661 gcaccatcga gtacatggcc cccgaaatca tccgtagcaa gacggggcat ggcaaggctg
721 tggactggtg gagcctgggc atcttgctct tcgagctgct gacgggggcc tcgcccttca
781 ccctggaggg cgagaggaac acgcaggctg aggtgtctcg acggatcctg aagtgctccc
841 ctcccttccc ccctcggatc gggcccgtgg cgcaggacct gctgcagcgg ctgctttgta
901 aggatcctaa gaagcgattg ggcgcggggc cccagggggc acaagaagtc cggaaccatc
961 ccttcttcca gggcctcgat tgggtggctc tggctgccag gaagattcca gccccattcc
1021 ggccccaaat ccgctcagag ctggatgtgg gcaactttgc ggaggaattc actcggctgg
1081 agcctgtcta ctcaccccct ggcagccccc cacctgggga cccccgaatc tttcagggat
1141 actcctttgt ggcaccctcc attctctttg accacaacaa cgcggtgatg accgatgggc
1201 tggaagcgcc tggtgctgga gaccggccag gtcgggcagc ggtggccagg agcgctatga
1261 tgcaggactc gcccttcttc cagcagtacg agctggacct gcgggagcct gcgctgggcc
1321 agggcagctt ttctgtgtgt cgccgctgcc gccagcgcca gagcggccag gagttcgcag
1381 tcaagatcct cagtcgcagg ctggaggcga acacgcagcg cgaagtggct gccctgcgcc
1441 tgtgccagtc acaccccaac gtggtgaatc tgcacgaggt gcatcacgac cagctgcaca
1501 cgtacctggt cctggagctg ctgcggggcg gggagctgct ggagcacatc cgcaagaagc
1561 ggcacttcag cgagtcggaa gcaagccaga tcctgcgcag cctcgtgtcg gccgtgagct
1621 tcatgcacga ggaggcgggc gtggtgcacc gcgacctcaa gccggagaac atcctgtacg
1681 ccgacgacac gcccggggcc ccggtgaaaa tcatcgactt cgggttcgcg cggttgcggc
1741 cgcagagtcc cggggtgccc atgcagacgc cctgcttcac gctgcagtac gctgcccccg
1801 agctgctggc gcagcagggc tacgacgagt cctgcgacct ctggagcctg ggcgtcattc
1861 tgtacatgat gctgtcgggg caggtcccct tccagggggc ctctggccag ggcgggcaga
1921 gccaggcggc cgagatcatg tgcaaaatcc gcgaggggcg cttctccctt gacggggagg
1981 cctggcaggg tgtatccgag gaagccaagg agctggtccg agggctcctg accgtggacc
2041 ccgccaagcg gctgaagctc gagggactgc ggggcagctc gtggctgcag gacggcagcg
2101 cgcgctcctc gcccccgctc cggacgcccg acgtgctcga gtcctctggg cccgcagtgc
2161 gctcgggtct caacgccacc ttcatggcat tcaaccgggg caagcgggag ggcttcttcc
2221 tgaagagcgt ggagaatgca cccctggcca agcggcggaa gcagaagctg cggagcgcca
2281 ccgcctcccg ccggggctcc cctgcaccag ccaacccggg ccgagccccc gtcgcctcca
2341 aaggggcccc ccgccgagcc aacggccccc tgcccccctc ctaatcccca ccactgtgac
2401 ccccttccct cataggggct gtgacctggg agcccggctc actcccggag gcctctgcct
2461 gcggctgacc tgatccccaa gggactgtcc tttcctctcc taccccaccc cactcccaga
2521 cagagcagaa gtatttttat aagcagagaa ttttttatgt cttaccagat agagttgcag
2581 ggaagggggg gcctgctggg gagtggggtt tggggggccc tctcccagga cactgcctct
2641 tctgggcaga aggcccctcc agggggactg ctccaacagg aaagagcccc tcccccactt
2701 ctaagcactg agttaggagt gctaactcct aaactgggac cccctaccct gttctcccct
2761 gaggccccgt tcctgggagg ggcacccctc aactgtcact ttatggactg tctgtgcaat
2821 tacgtccacc aaagacccgt gttgggggta ctgaaggaga ggccctgggg gaccctctga
2881 agcatttctg cctcacttta tgtcatctgc ttctcccctg ttggggctaa ggaaggagat
2941 aggtggctcc taaaagagga ggccatcttc tcacccaccc cttcctcttt ggcacagcta
3001 ctcctggctg ggggtggggc cttgggggtc tgggctgggc atccatggtc actgcctcag
3061 cccagccagg ctgtgccttt gactttaaaa taaaagtcca cccagtgctg tgtgtggcaa
3121 aaaaaaaaaa a
//