LOCUS AJ001687 6390 bp DNA linear HUM 14-NOV-2006
DEFINITION Homo sapiens NKG2D gene, exons 2-5 and joined mRNA and CDS.
ACCESSION AJ001687
VERSION AJ001687.1
KEYWORDS NKG2 gene; NKG2D gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6390)
AUTHORS Francis F.
JOURNAL Submitted (19-SEP-1997) to the INSDC. Francis F., Dept. Lehrach,
Max-Planck Institut fuer Molekulare Genetik, Ihnestrasse 73,
Berlin, 14195, GERMANY.
REFERENCE 3
AUTHORS Glienke J., Sobanov Y., Brostjan C., Steffens C., Nguyen C.,
Lehrach H., Hofer E., Francis F.
TITLE The genomic organization of NKG2C, E, F, and D receptor genes in
the human natural killer gene complex
JOURNAL Immunogenetics 48(3), 163-173(1998).
PUBMED 9683661
FEATURES Location/Qualifiers
source 1..6390
/organism="Homo sapiens"
/chromosome="12"
/map="12p"
/mol_type="genomic DNA"
/clone_lib="PAC library (P. de Jong)"
/clone="From PAC clone D21184"
/db_xref="taxon:9606"
exon 661..717
/gene="NKG2D"
/number=2
mRNA join(AJ001686.1:1992..2122,661..717,2524..2608,3676..3780,
5541..5648,AJ001688.1:241..333,AJ001688.1:551..586,
AJ001688.1:1328..1479,AJ001688.1:1798..1901,
AJ001689.1:1074..1947)
/gene="NKG2D"
intron 718..2523
/gene="NKG2D"
/number=2
exon 2524..2608
/gene="NKG2D"
/number=3
intron 2609..3675
/gene="NKG2D"
/number=3
exon 3676..3780
/gene="NKG2D"
/number=4
CDS join(3741..3780,5541..5648,AJ001688.1:241..333,
AJ001688.1:551..586,AJ001688.1:1328..1479,
AJ001688.1:1798..1901,AJ001689.1:1074..1191)
/gene="NKG2D"
/db_xref="GOA:P26718"
/db_xref="HGNC:HGNC:18788"
/db_xref="InterPro:IPR001304"
/db_xref="InterPro:IPR016186"
/db_xref="InterPro:IPR016187"
/db_xref="InterPro:IPR033992"
/db_xref="InterPro:IPR042169"
/db_xref="PDB:1HYR"
/db_xref="PDB:1KCG"
/db_xref="PDB:1MPU"
/db_xref="PDB:4PDC"
/db_xref="PDB:4S0U"
/db_xref="UniProtKB/Swiss-Prot:P26718"
/protein_id="CAA04925.1"
/translation="MGWIRGRRSRHSWEMSEFHNYNLDLKKSDFSTRWQKQRCPVVKS
KCRENASPFFFCCFIAVAMGIRFIIMVAIWSAVFLNSLFNQEVQIPLTESYCGPCPKN
WICYKNNCYQFFDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHI
PTNGSWQWEDGSILSPNLLTIIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV"
intron 3781..5540
/gene="NKG2D"
/number=4
exon 5541..5648
/gene="NKG2D"
/number=5
BASE COUNT 2116 a 984 c 1046 g 2244 t
ORIGIN
1 acaagttggg tgcgtgttaa gtctttcctg tgtaccagaa gagaagggtt ttctgaggcc
61 acagtgcgag ttagcttact gaccaaaaag gccggttgat tgttggctct tctcaactaa
121 tgaaagtaat taaatagttt attgtggtga tggatgttct caaatgactt gagcccaggc
181 tgtttgcaaa gtattgtaat ttttcttcta acaatagttt ttgaaagtta tatagatacg
241 tctatatgaa gtttgttcag gtacttttat agtcaaatta ttctttctgc agaagttaat
301 tgcgttggtt ttatttcact tattagaaag tattttatct gaaaactatg ctatgtcctt
361 ttgcaattca catagaataa accagtacaa atgcccagca aatccccaat aagtttacta
421 tcatgactac agcaaagtga gtgtatgttc aacattgaga aagaaattgg agttttaaca
481 tactatttct ttatctaact aattgtttta acccgacata caggacccat tttagaattt
541 tcttctttaa gaatcctttc cacactctgt cagttggttt agggaccttt atatatgaca
601 ataaaactct ccctggtgct tagctttatc atggtattta tttcagaaat cttcttttag
661 gtatgtgtgg ggacttccca gttggctgta agttgccatt tgaactaaac gaaataggta
721 ggatattcaa atgttctttt ttatcctatt cctatccccc ttttctcaat tctgtattta
781 agagacaatc tctattcaat cgaaaactac atatataaaa ataactcttc aggaaattgt
841 gattcaggtt tttcccataa aaagcctgca tttactcatt tattcatttc ctttcaaaaa
901 ccaaatattt gttaaaatgt agttgttaga aaatatcagc ctatatttcc tctatataga
961 tctattttta ctatataaaa tagctaatag aaaatgttga ttagctgaaa agaatcttgg
1021 tatgtcagaa aataacatat tttcttcaac ttgttttata ttcacctatc ttgtttaatt
1081 ttgaatttgt tttatactta ttcattttat atcacctaaa ctaaaaagta atttccagct
1141 gggtgtggtg gctcacgtct gtaatctcag cacattggga ggctgaggca ggaggatcac
1201 ctgaggtcag gagttcgaga ccagcctgac taacatggtg aaacctcgtc tctactagaa
1261 atacaaaaat tagccaggtg tggcggcaca tgcctgtaat cccagttatt ctggaggctg
1321 agacaggaga attgcttgaa cccaggtggc ggaggttgca gtgagccgag atcgccccgt
1381 tgcactccag cctggacgac aagagtgaaa ctccatctct taaaaaaaaa aaaaaaaaag
1441 taattaattt ccatgtgggc aaaaactttc ttttggattg tttactttga cattctcaag
1501 atctagaaaa gtgcatagca aatagcattc gctaaagaaa aaaaatgttg aataaattta
1561 ttgtccaact ttaacacatc accacatgaa agctgttttc cttccttata tttcagagtt
1621 ttaagattaa tagctttggt ttttgttaaa atgttataat gtgttcatct tatattactt
1681 tatatgatgt cttatgttag tattttaaat taataaacat aaaatatata tttagcttat
1741 cttgttcatt ggtatcaatt catatattat tcttatgtat actggggtat atatttaagt
1801 ttctaattct tctgcatatg atgtagatat gacagagatg caatttcatg ttttttatat
1861 taaaatttaa aaattcccag gactaatttt ttgtaactta aaggccagtg tgatagtaac
1921 ccaggacaaa ttattgaata ggagctaatt tcccacttta tctgcaatgt taccttatat
1981 tttttaatct atgcacatga ctttttcttg tctgtatttt tacccttctc aatttgtcta
2041 tctatgcccc acatgccact ttgcctttat taatacggtt ttaacatagg tcttactatc
2101 tagtaaaaca aggctcccac attttcttca tcttcaattg tgactttcct agtcttgact
2161 tttgtaattt aatgtacatg tagaattctg ctttgtaagt tctacaacaa aacctgaggt
2221 attaactgga attgaattga atctctaaaa tatttaggat taaatggcat catttaaatt
2281 catcattttc aaatcctaaa atgttattta aaataatggc aaaactacaa ttacttttgc
2341 accaacctaa catttatcca acaatgggtg gtcttaactc ttttaccaaa ttaacaatat
2401 ttttgtagtg ataaggcgga agtactgtgg tttatgtttt tccacaggaa gatgagatta
2461 taatatttgt cacatctttc tcaaagatag aaattcacta agtatctcca ctttcaattc
2521 tagatcagga actgaggaca tatctaaatt ttctagtttt atagaaggct tttatccaca
2581 agaatcaaga tcttccctct ctgagcaggt gtgtgtatgt gtgtatgtgt gtgtgtttat
2641 tattcaagat atgagaaatt atatttcaac ctcaaaaaaa taaaaatatt tacactataa
2701 ggtaattcta attgtttctt agatgcttga atagaactcc tgaggatacg gaatgcttat
2761 catttctgat gtatattcta tcactgtatc tgatgatagg taattaggat atacttattg
2821 aagaatcaga agttgtaata ttactataag aagaagcctt gtctctaagc aaaactagaa
2881 aaatgaatct ttacatttag gatgagaaga attgagattc aatttaaatt gtcaaatttt
2941 tgagttttct gatgctgtag ggggcactta cctttgatac acatctttac atgcaaggtg
3001 aaacaagtta tatctgtgct ttccaactat cataatcaaa tatgaaatag cttttatttt
3061 tgaaatctaa gcactatgct tatttattaa atggtttttt ctggaagctc tgctgtgcat
3121 tgctaagatg ttactatata aacatgtgag attagttttg ttaatgatga tggtgatgat
3181 aatttgttga tgatgatgat atgggcacgt tggattaaaa tgcactagaa aaggacattc
3241 aacaaaagtg catataactt acctgagttt agcttgcaga aagaaaacta aattattgcc
3301 agataaaata aacaactaga aacacttgat cttagctaaa aggccaagaa gcaataaacg
3361 actataaaca gaaaactggg tgtgttgtta tctaatatca gtaacgtaaa atattggtat
3421 taaatatctc aatgtaggtg aattaatagg ttcattatat tgttatgaca ttttgaagta
3481 attggcgatt attttacaac caagagaaat gtataaaatt aattttgcct ggctttatgt
3541 gaattgtcat ttctattctt ttcttaaagg catgcacagg ggaaaagttt ctgcatttta
3601 cttttctatt caaaatattt tatctcacca cgggaaagag aacaaaaaac aaatgcccag
3661 ttttatttta ttcaggaatc ctttgtgcat tgaagacttt agattcctct ctgcggtaga
3721 cgtgcactta taagtatttg atggggtgga ttcgtggtcg gaggtctcga cacagctggg
3781 gtatgttttt accacataag tgtgtagttt tgtttttata caattttaag ataccaagaa
3841 tttcatacaa gcatataagg cataggcaag caatttactc tgattctttt catgttctat
3901 ttatgttgat ttcatgttat gttcatattg tattttaaat caagtcttcc aaaacttaaa
3961 aacttttttc cctttatttt attaactata ttatggtaaa gtcgctcaca acttgggaca
4021 gcttgaaata gtgaaataga tgtggagtca gacttgaatt ttactcaaac ttttaccgct
4081 ctctagattt gaagggtcaa tttgcaacct ctgtgtagtt tagtttagtt tctttttcta
4141 tcaaatacag gcatgaaaca ttccatattt atcttagatt tgtgtaatat tcaaatcaac
4201 tgacatgtat gttaaagcac tttttatcct aaaggtgttt ataaatttat aacttattca
4261 cagttggtaa cattatatta aataagcttt atgattttgg ccatctctag cattcaattt
4321 cttcatccat aaagtgatac ctactctctt tactccatat gtaaaataac tgagttaggt
4381 attacatgcg caatcaatgt ctaattttac ctataaaata taattcatat tatcatttaa
4441 tttataaaag gcttttgtac aacaaacccc cgtgacatga atttacatat gtaacaaacc
4501 ttcgcatgca cccctgaacc aaaaataaaa gtttaaaaaa ggcttttaag taaatattaa
4561 tcatcagtaa ataattaata tttcaagaga gcaaaatgat tctttaggta ttttgttcag
4621 aggcaagatt atctgtcttt gttctaaatc attagacccc actattttag cctatgtatg
4681 tccttcatta taaagaaaat tagatggctg ggcacagtgg ctcatgccta taatcccaga
4741 aatttgggag gctgaggtgg gtagatcacc tgtggtcagg agttcgagac cagcctggcc
4801 aatatggtga aaccccgtct gtactaaaaa tacaaaaatt agccaggtat ggtggcacaa
4861 gcctgtaatc ccagctactc aagaggctga ggcaggagaa ccgcttgaac ccaggaggcg
4921 gcggttgcag tgagccaata tcacgccatt gcactccatc tcaaaaaaaa aaaaagaaaa
4981 gaagaaaatt agacacactg ctatttacta aaagcttact aaatgattga tgttattgat
5041 gctaagttca ttatattttt attttatttt taaaataccc atactggatt gtgacagtat
5101 ccttttcttt tttatttctt tcgtcttttg caaattagga aaactgggat gcaaaagcta
5161 ggttatttgt gaagttatca agtttgtata tgtggatctg tgatttaaat acatgtcttt
5221 ctccctacat ctgccttttc actaaccaag tccctttctg gtaatgttag gtttcattat
5281 acattacgaa ttaactaatt ttaatagtat ataggatttt gctaagggta ctttgcatgg
5341 cataaatata gttttattta tatagtaaag tgtaaacata ataatgtagt actataaaac
5401 aaaagtaagt tcatgttgta ctttaaaaag gatagtcagg ggaagtacat agatggaaat
5461 ggcaagctga atttttaaaa tttatgcccc aaatggcaga aaggccatga ctcatataag
5521 cctgaattct ttttctctag agatgagtga atttcataat tataacttgg atctgaagaa
5581 gagtgatttt tcaacacgat ggcaaaagca aagatgtcca gtagtcaaaa gcaaatgtag
5641 agaaaatggt aagtcctatg ttccatttgt ctactctcag tatattgaaa tgaatcttgg
5701 aaactatgtg attaaatgaa tggcaatcat tcagttgact ttatcttcat gaggaaagca
5761 ggaataacat gaactctcat ataatattaa aatatataat aaaattatgg tattaaaagc
5821 tattgagttt agaatattgt cacgccctaa aaaatgatga gtttattatc atgataatat
5881 aatcgaggca ggagtttcta agagatcact gaaaagaaaa ctaaatagaa atgaaaaaga
5941 gaagagaaaa gatattttaa aaaccctcca gagatatgtt cctaaacatt atagaagtgg
6001 tagcttgatt attatttata gaattgtttc tgagttcagt gaagaagata tattctccaa
6061 tgactttttt caaagcagaa tattattggt aatagacctt tatatagttt gtatgaaaag
6121 gaaaacaaca gatgaccctc acttatcaat ttttattaaa aactaagaaa caaattatta
6181 acaaatagca tctctttaca agaattaatt taaggaatgc aaagtgctat atgtaaaaat
6241 ccctttttgg actaaaatat tcaattgtta ccaaaattta aaacacacat gccctttccc
6301 tcaacaatta tcattgtggg aatttatccc agagagagac tcaaaaatat gcacagatgg
6361 gtatgaaatg tatcattatt tctcatagca
//