LOCUS AJ001017 6967 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens partial mRNA for TBP-associated factor 170 (TAFII170).
ACCESSION AJ001017 AF166117
VERSION AJ001017.2
KEYWORDS TAFII170 gene; transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Timmers M.
JOURNAL Submitted (02-SEP-1997) to the INSDC. Timmers M., Laboratory for
Physiological Chemistry, Utrecht University, Universiteitsweg 100,
3438 GD, THE NETHERLANDS.
REMARK revised by [3]
REFERENCE 2
AUTHORS VanderKnaap J.A., Borst J., VanderVliet P.C., Gentz R.,
Timmers H.T.M.
TITLE Cloning of the cDNA for the TAFII170 subunit of transcription
factor B-TFIID reveals homology to global transcription regulators
in yeast and Drosophila
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94(22), 11827-11832(1997).
PUBMED 9342322
REFERENCE 3
AUTHORS Timmers M.
JOURNAL Submitted (20-MAR-1998) to the INSDC. Timmers M., Laboratory for
Physiological Chemistry, Utrecht University, Universiteitsweg 100,
3438 GD, THE NETHERLANDS.
REMARK revised by [4]
REFERENCE 4 (bases 1 to 6967)
AUTHORS Timmers M.
JOURNAL Submitted (15-FEB-2000) to the INSDC. Timmers M., Laboratory for
Physiological Chemistry, Utrecht University, Universiteitsweg 100,
3438 GD, THE NETHERLANDS.
REFERENCE 5
AUTHORS Van Der Knaap J.A., Van Den Boom V., Kuipers J., Van Eijk M.J.,
Van Der Vliet P.C., Timmers H.T.
TITLE The gene for human TATA-binding-protein-associated factor (TAFII)
170: structure, promoter and chromosomal localization
JOURNAL Biochem. J. 345, 521-527(2000).
PUBMED 10642510
FEATURES Location/Qualifiers
source 1..6967
/db_xref="H-InvDB:HIT000243826"
/organism="Homo sapiens"
/chromosome="10"
/map="10q22-q23; between D10S185 and WI-1183"
/mol_type="mRNA"
/clone="3N10"
/cell_line="Nalm-6"
/cell_type="B-cell"
/db_xref="taxon:9606"
CDS <13..5562
/codon_start=1
/gene="TAFII170"
/product="TBP associated factor"
/function="transcription factor"
/note="similar to Mot1; identical to TAF172"
/db_xref="GOA:O14981"
/db_xref="H-InvDB:HIT000243826.14"
/db_xref="HGNC:HGNC:17307"
/db_xref="InterPro:IPR000330"
/db_xref="InterPro:IPR001650"
/db_xref="InterPro:IPR011989"
/db_xref="InterPro:IPR014001"
/db_xref="InterPro:IPR016024"
/db_xref="InterPro:IPR022707"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR038718"
/db_xref="UniProtKB/Swiss-Prot:O14981"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAA04475.1"
/translation="MAVSRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLL
SKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTRQEPTSESSMEDSPTTERLN
FDRFDICRLLQHGASLLGSAGAEFEVQDEKSGEVDPKERIARQRKLLQKKLGLNMGEA
IGMSTEELFNDEDLDYTPTSASFVNKQPTLQAAELIDSEFRAGMSNRQKNKAKRMAKL
FAKQRSRDAVETNEKSNDSTDGEPEEKRRKIANVVINQSANDSKVLIDNIPDSSSLIE
ETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQ
HQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVD
VLLKLLTQEQWEVRHGGLLGIKYALAVRQDVINTLLPKVLTRIIEGLQDLDDDVRAVA
AASLVPVVESLVYLQTQKVPFIINTLWDALLELDDLTASTNSIMTLLSSLLTYPQVQQ
CSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTLLSTQDQNSSSWLIPILPDMLRH
IFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPIDL
NMLLEVKARAKEKTGGKVRQGQSQNKEVLQEYIAGADTIMEDPATRDFVVMRARMMAA
KLLGALCCCICDPGVNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEWAALQ
KECKAVTLAVQPRLLDILSEHLYYDEIAVPFTRMQNECKQLISSLADVHIEVGNRVNN
NVLTIDQASDLVTTVFNEATSSFDLNPQVLQQLDSKRQQVQMTVTETNQEWQVLQLRV
HTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQCIAKLLQQCTTRTPC
PNSKIIKNLCSSLCVDPYLTPCVTCPVPTQSGQENSKGSTSEKDGMHHTVTKHRGIIT
LYRHQKAAFAITSRRGPTPKAVKAQIADLPAGSSGNILVELDEAQKPYLVQRRGAEFA
LTTIVKHFGGEMAVKLPHLWDAMVGPLRNTIDINNFDGKSLLDKGDSPAQELVNSLQV
FETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFL
EKVLPWLGAIDDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRF
MATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPI
NAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSK
LAECMPLPSLVVCPPTLTGHWVDEVGKFCSREYLNPLHYTGPPTERIRLQHQVKRHNL
IVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPI
QNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHR
QVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSAT
LSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDI
QHAPKLSALKQLLLDCGLGNGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPH
LPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEH
DWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENS
SLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASMKSILENLSDLWDQEQYDSEYSLE
NFMHSLK"
3'UTR 5563..6967
/gene="TAFII170"
regulatory 6927..6932
/gene="TAFII170"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 2184 a 1278 c 1471 g 2034 t
ORIGIN
1 cggcgcccgg ccatggcggt ctccaggcta gatcgccttt ttattttact ggatactggc
61 actactcctg ttacaagaaa agctgctgca cagcaacttg gagaagtggt gaagcttcat
121 ccccatgaac taaataatct cctgtctaaa gtgttgatat atttaaggag tgcaaattgg
181 gatacccgga ttgcagcagg acaagctgtt gaagctatag tgaaaaatgt acctgagtgg
241 aatccagtgc cgagaaccag acaagaacct acttccgaaa gttctatgga agattcacct
301 actacagagc gattgaattt tgacagattt gatatatgta gattgttaca acatggtgca
361 tcactcctgg gatctgctgg tgccgaattt gaagtccaag atgaaaaatc aggtgaagtg
421 gatcctaaag agaggatagc acgccaacga aaattattac agaagaaact tggccttaat
481 atgggagaag caattggaat gagtactgaa gaacttttca atgatgagga tttggattat
541 accccaactt cagcatcctt tgttaacaaa caacctactc ttcaggcagc tgaattgatt
601 gactcagagt ttcgagcagg aatgagcaat agacaaaaga acaaagctaa aagaatggcc
661 aagttatttg caaaacagag atccagggat gcagtggaaa ctaatgagaa gagcaatgat
721 agcactgatg gggagccaga agaaaagaga cggaaaatag caaatgttgt tattaatcag
781 tctgcaaatg attccaaagt cttgattgat aatattccag acagctcttc cttaattgaa
841 gagacaaatg aatggccttt ggaaagcttt tgtgaagaac tttgcaatga cctttttaat
901 ccctcctggg aggttcgaca tggtgcaggc actggactta gggaaattct taaagctcat
961 gggaaaagtg gtggtaaaat gggtgacagc actttagaag agatgattca gcagcatcaa
1021 gagtggttgg aagacttggt tattagactc ctttgtgttt ttgcattaga cagatttgga
1081 gactttgttt ctgatgaagt tgtggcacca gttcgtgaaa cttgtgctca aacattaggt
1141 gtggttttaa aacacatgaa cgaaacagga gttcataaga ctgtggatgt gctgctaaaa
1201 ttacttacac aagaacaatg ggaagttaga catggtggtc tgctgggaat aaaatatgct
1261 ttggcagtcc gtcaggatgt aattaatact ttattgccta aagttttaac tagaataatt
1321 gaaggactcc aggatcttga tgatgatgtc agagctgttg ctgcagcatc attagtgcct
1381 gtagtagaaa gccttgtcta tcttcagaca caaaaggtgc ccttcattat aaatacattg
1441 tgggatgctc ttctggaatt agatgatcta acagcttcaa caaatagtat tatgactctc
1501 ctttcatcct tgttaactta ccctcaggtc caacaatgca gtattcagca gtcactgaca
1561 gttttagttc cacgtgtctg gccttttttg catcacacta tatcatcagt tcgaagagca
1621 gcattggaaa ctctgtttac gttattatca acacaggacc agaactcttc atcttggctt
1681 atacctatac tgcctgatat gctccgacac atttttcagt tctgtgtttt ggaaagcagc
1741 caggaaattc tggaccttat tcacaaggtt tggatggaac tgttgagtaa ggcttcagtt
1801 cagtatgtgg tagcagctgc ttgcccatgg atgggtgctt ggctttgctt gatgatgcag
1861 ccttctcatt tacctatcga tttaaatatg ttgctagaag taaaagctag agccaaggaa
1921 aaaacaggtg gtaaggtgcg ccaaggccaa agccagaata aagaagtact tcaggagtat
1981 attgcaggtg ccgacaccat catggaagac ccagccacca gggattttgt agttatgcgg
2041 gccagaatga tggcagccaa gttgttagga gcactttgtt gctgtatttg tgatccaggt
2101 gtaaatgtgg taactcaaga aattaaacca gctgaatccc tgggccagtt actactcttc
2161 catttgaact ccaagtctgc tttacagagg attagtgtag ctttggtaat ctgtgaatgg
2221 gctgctttac aaaaggagtg taaagctgtt accttagctg tgcagccgcg tttacttgat
2281 atcctttcag aacatttata ttatgacgaa attgccgttc cattcacacg aatgcagaat
2341 gaatgtaaac aacttatatc atcattagct gatgtacata tcgaagttgg taatcgagta
2401 aacaacaatg ttttaacaat agatcaagct agtgacttgg tcactactgt ttttaatgaa
2461 gccacatcat ctttcgattt aaatcctcaa gtgttacaac agttagatag taaacgacag
2521 caggtccaaa tgacagttac agagaccaac caggagtggc aagtgttgca gttgagagtg
2581 catacttttg ctgcctgtgc agttgtgagc ttgcagcagc ttccggagaa attaaatcct
2641 atcataaaac cattaatgga gacaattaaa aaagaagaga atacactagt gcaaaactat
2701 gcagctcagt gcatagctaa actccttcag cagtgcacaa caaggacgcc ctgtcccaat
2761 tcaaaaatta ttaaaaacct ctgtagctca ctttgtgtgg acccatatct aactccttgt
2821 gtcacatgtc cagtaccaac acaaagtggc caggaaaatt ctaaaggatc cacctcagaa
2881 aaagatggaa tgcaccatac tgtcaccaag cacagaggta taattacact ctacaggcac
2941 cagaaagctg cctttgctat cacaagtagg cgaggtccta cccccaaagc agtaaaagct
3001 caaatagcag atcttcctgc aggaagtagt ggaaatattc ttgttgaact tgatgaggcc
3061 cagaagcctt acctggtaca acggagagga gctgaatttg ctttgacaac tatagtaaag
3121 cattttggtg gtgaaatggc agtgaagttg ccacatctct gggatgctat ggttggccca
3181 ttgaggaata caatcgacat aaataatttt gatggaaaat ccctcctgga taagggagat
3241 agccctgctc aagaattggt gaattctctg caggtttttg aaacagcagc agcttcaatg
3301 gattctgagc ttcatccctt gttggtccag catttgccac atctttatat gtgccttcaa
3361 taccccagta ctgcagtgag gcacatggct gctcgttgtg taggtgtcat gagcaaaata
3421 gctaccatgg aaacaatgaa tatttttttg gagaaggttc ttccgtggct gggagcaatt
3481 gatgacagtg tcaaacaaga gggtgcaatt gaagcacttg cctgtgtaat ggaacaacta
3541 gatgttggta ttgttccata tattgtcctt ttagttgttc ctgtattagg aagaatgagt
3601 gatcagacag acagtgtgag attcatggcc acgcagtgct ttgcaacgct aattagactc
3661 atgccacttg aggcaggcat tccagaccct ccaaacatgt cagcagaatt aatccaattg
3721 aaagccaagg agcgacactt tttggagcaa ttgttagatg ggaaaaaatt ggaaaattat
3781 aaaattccag taccaatcaa tgctgaactc agaaaatatc agcaggatgg tgtgaactgg
3841 ttagcatttc ttaataagta taaacttcat ggaattctgt gtgatgacat gggtttagga
3901 aaaactttac agtccatctg cattctagca ggagatcatt gtcatagggc ccaggaatat
3961 gcaagatcaa aattagcaga atgtatgcca cttccttcct tagtggtttg tccgccaaca
4021 ttaacaggcc attgggtgga tgaagtaggt aaattttgct ctagagaata tctcaacccg
4081 ttgcattaca ctggacctcc cactgaaaga ataaggttac agcaccaagt aaaaaggcac
4141 aatctaatag tggcttcata tgatgttgtg aggaatgaca tagatttctt tagaaatatt
4201 aaatttaact actgcattct tgatgaaggc catgtcatca aaaatggaaa aacaaagttg
4261 tcaaaagcag taaaacaact gactgctaat tataggatta ttctttctgg aacaccaatc
4321 cagaacaacg ttttggagct gtggtcatta tttgatttcc tcatgccagg atttttgggt
4381 actgaacgcc agtttgctgc tcgatatggt aaacctatat tagcaagtag ggatgctcga
4441 agctccagtc gagagcaaga agcaggtgtt cttgctatgg atgcgctgca ccgccaagta
4501 ctaccgtttc ttttgagaag aatgaaagaa gatgttttgc aggatcttcc acctaaaatt
4561 attcaagact attattgtac tcttagtcct ctccaggttc agctctatga agattttgct
4621 aagtctcgtg ccaagtgtga tgttgatgaa acagtttctt cagctacact ttctgaagaa
4681 actgaaaaac caaagcttaa agctacaggc cacgtattcc aggcattaca gtacttacgt
4741 aaactgtgca accatccagc attagtctta acacctcaac atccagaatt caagaccact
4801 gccgaaaaac tggcagttca gaattcttct ctacatgata ttcaacatgc ccctaagctc
4861 tcagctttga aacaattgct gttggactgc ggtttgggaa atggcagcac ttccgagagt
4921 ggcacagagt ctgttgtggc ccagcacagg atactgatat tctgtcagct gaaaagcatg
4981 cttgatatag tagagcatga tctcctcaaa cctcacttgc cctctgtcac ttatttgaga
5041 ttagatggca gcatacctcc tggtcagagg cattccattg tttcccggtt taataatgat
5101 ccatctatag acgttctgtt acttaccact cacgttggtg gcctgggact taatttgaca
5161 ggcgctgaca cagtagtatt tgtggagcat gactggaatc ctatgcgaga tctacaagcc
5221 atggaccggg cccatcgcat tgggcagaaa cgtgtggtta acgtataccg attgataacc
5281 agaggaacat tggaagaaaa aataatgggg ttgcagaaat tcaagatgaa catagcgaat
5341 actgttatta gccaagagaa ttctagtttg cagagcatgg ggactgatca gcttcttgat
5401 ctgtttactc ttgataagga tggcaaagca gaaaaagctg acacctctac ttctgggaaa
5461 gcaagtatga aatcaattct tgaaaacctg agtgatcttt gggatcaaga gcagtatgat
5521 tcagagtaca gcctggaaaa ttttatgcat tctctcaagt aactatcaaa tattgtaaat
5581 gcaattgctg ctagttcagt tacatttctg ctgatattca gcaaatttct aagtttatgg
5641 tgaactttta actcaatgtg taaatagatc tggagaatat tcagcataat gctggctctt
5701 gtttcactgg gggaaacaag ttattctcaa atatttgcac tgtattaaat ttaaatgtta
5761 atgtgaaatg gtttaaattt tacatgctga aaagctgcag agcagaggaa ccaaaccagg
5821 tttatttgtg ctaccaggag gtgttcttaa tgggaacagg cctcctatct ttagtcactt
5881 tgtacaggat gatatccatg agtactttag tgtttgtata tgttttttct tttaaataga
5941 acttgttttt ataattgatt taaaataggg cttttttcta taaaagcctt aatgagccat
6001 aattttaaga atataagaat aatgactatg atattggtca gtcttagaac atgaaaatgt
6061 cagacaatga atttaatcgg gcccttggtg gaaacattta tatatttaat gcagatgcat
6121 agtgtttttc aaatctttaa catcattttt tcaactttta agatataata tcaactattc
6181 taaatacagg taatggtata tttaaggcta ccataacatc ctatttagag ggtggttttt
6241 tttaatttat ctaatggcta cgatatagcc agattcaaat aacatatgta ctcaataggt
6301 ttcaatcata tatataatat attttttgta actatgaaca tacacagttt tccagaaata
6361 gattttacac tgtttagaat tccaacacct acagtggaaa gactgtttat tgtagtaatg
6421 catggctgaa gcataaaagg gagagagaat ttctttatat acacaaacat acatgaatat
6481 gcacatctat atgcatagat gtacctatcc tgcacccaaa aaggtgcctg gtattggcac
6541 taaaatcatg tagttatact gggcagcaat aataattggg catgaggctg attactcaat
6601 ggtgagggta ggtatatgta gatagatgtg catgtatgtg tttgtatata taattttata
6661 agtttcacgc ataaattaat acatgcctgt gtgcatacat atgtatggga tatatttgta
6721 tatatatgta caggtaataa acatccccaa ggtttgtggc tggccataca cataggcatc
6781 agtttaacaa ccatcagacc tcagctgtac aataacaggt gttttgttta attaaaatta
6841 tactgttctg cagcatttag acatttgtca catttcatta gctttgacaa ccatactgta
6901 acattaaacc tagcattcca caagagaata aatataagat tgaaactgta aaaaaaaaaa
6961 aaaaaaa
//