LOCUS AJ000327 3547 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for adrenoleukodystrophy related protein (ALDR).
ACCESSION AJ000327
VERSION AJ000327.1
KEYWORDS adrenoleukodystrophy related protein; ALDR gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Holzinger A.
JOURNAL Submitted (07-JUL-1997) to the INSDC. Holzinger A., Department of
Clinical Chemistry and Metabolism, LMU Dr. v. Hauner Children's
Hospital, Lindwurmstrasse 4, Munich, 80337, GERMANY.
REMARK Revised by [3]
REFERENCE 2
AUTHORS Holzinger A., Kammerer S., Berger J., Roscher A.A.
TITLE cDNA cloning and mRNA expression of the human adrenoleukodystrophy
related protein (ALDRP), a peroxisomal ABC transporter
JOURNAL Biochem. Biophys. Res. Commun. 239(1), 261-264(1997).
PUBMED 9345306
REFERENCE 3 (bases 1 to 3547)
AUTHORS Holzinger A.
JOURNAL Submitted (31-OCT-1997) to the INSDC. Holzinger A., Department of
Clinical Chemistry and Metabolism, LMU Dr. v. Hauner Children's
Hospital, Lindwurmstrasse 4, Munich, 80337, GERMANY.
REFERENCE 4
AUTHORS Holzinger A., Mayerhofer P., Berger J., Lichtner P., Kammerer S.,
Roscher A.A.
TITLE Full length cDNA cloning, promoter sequence, and genomic
organization of the human adrenoleukodystrophy related (ALDR) gene
functionally redundant to the gene responsible for X-linked
adrenoleukodystrophy
JOURNAL Biochem. Biophys. Res. Commun. 258(2), 436-442(1999).
PUBMED 10329405
FEATURES Location/Qualifiers
source 1..3547
/db_xref="H-InvDB:HIT000243801"
/organism="Homo sapiens"
/chromosome="12"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 136..2358
/codon_start=1
/gene="ALDR"
/product="adrenoleukodystrophy related protein"
/function="peroxisomal ABC-transporter"
/db_xref="GOA:Q9UBJ2"
/db_xref="H-InvDB:HIT000243801.14"
/db_xref="HGNC:HGNC:66"
/db_xref="InterPro:IPR003439"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR011527"
/db_xref="InterPro:IPR017871"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR031239"
/db_xref="InterPro:IPR036640"
/db_xref="UniProtKB/Swiss-Prot:Q9UBJ2"
/protein_id="CAA03994.1"
/translation="MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRL
KQSGHGKKKAAAYPAAENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTT
ETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFV
NSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFS
QSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSP
KFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLIL
SKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATGFADGEDGQKQVMVSERTEAFTTA
RNLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESH
SKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLL
ITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDS
VDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFY
HKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGG
WRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIKNEDETS
"
polyA_site 2361
BASE COUNT 1179 a 623 c 717 g 1027 t
ORIGIN
1 aaaacacaac agtggaagag aaacgctgca tactatggga cgctgtagga ctttctaaaa
61 catttgctgg ggatttctgt gaagcatgat cttttaaacg aattcttttg gaagccggtt
121 tgggtaactg ggaaaatgac acatatgcta aatgcagcag ctgatcgagt gaaatggacc
181 agatcgagtg ctgctaagag ggctgcctgc ctggtggctg cggcatatgc tctgaaaacc
241 ctctatccca tcattggcaa gcgtttaaag caatctggcc acgggaagaa aaaagcagca
301 gcttaccctg ctgcagagaa cacagaaata ctgcattgca ccgagaccat ttgtgaaaaa
361 ccttcgcctg gagtgaatgc agatttcttc aaacagctac tagaacttcg gaaaattttg
421 tttccaaaac ttgtgaccac tgaaacaggg tggctctgcc tgcactcagt ggctctaatc
481 tcaagaacct ttctttctat ctatgtggct ggtctggatg gaaaaatcgt gaaaagcatt
541 gtggaaaaga agcctcggac tttcatcatc aaattaatca agtggcttat gattgccatc
601 cctgctacct tcgtcaacag tgcaataagg tacctggaat gcaaattggc tttggccttc
661 agaactcgcc tagtagacca cgcctatgaa acctatttta caaatcagac ttattataaa
721 gtgatcaata tggatgggag gctggcaaac cctgaccaat ctcttacgga ggatattatg
781 atgttctccc aatctgtggc tcacttgtat tccaatctga ccaaacctat tttagatgta
841 atgctgacct cctatacact cattcaaact gctacatcca gaggagcaag cccaattggg
901 cccaccctac tagcaggact tgtggtgtat gccactgcta aagtgttaaa agcctgttct
961 cccaaatttg gcaaactggt ggcagaggaa gcacatagaa aaggctattt gcggtatgtg
1021 cactcgagaa ttatagccaa tgtagaagaa attgcctttt acagaggaca taaggtagaa
1081 atgaaacaac ttcagaaaag ttacaaagct ttagcagatc agatgaacct cattttatcc
1141 aaacgtttgt ggtacatcat gatagaacag ttcctgatga agtatgtttg gagcagcagt
1201 ggactaatta tggtggctat acctattatc actgcaactg gctttgcaga tggtgaggat
1261 ggccaaaagc aagttatggt tagtgaacgg acagaagcct ttaccactgc tcgaaattta
1321 ctggcctctg gagctgatgc tattgaaagg attatgtctt catacaaaga ggtcactgaa
1381 ttagcaggct acactgctcg agtgtacaat atgttttggg tctttgatga agtaaaaaga
1441 ggcatttata agagaactgc tgtcattcaa gaatctgaaa gccatagcaa gaatggagct
1501 aaggtagaat tacctctcag tgacacattg gcaattaaag gaaaagttat tgatgtggat
1561 cacggaatta tttgtgaaaa tgttcccata attacaccag caggagaagt ggtggcttcc
1621 aggctaaact tcaaagtaga agaaggaatg catcttttga taactggtcc caatggttgt
1681 gggaaaagtt ctctcttcag aattctaagt gggctctggc ctgtgtatga aggagtcctc
1741 tataaaccac ctcctcaaca tatgttttat attccacaaa ggccatatat gtctcttgga
1801 agtcttcggg atcaagtcat ttaccctgat tcagtggatg atatgcatga taaaggttat
1861 acagaccaag atctggaacg tatcctacac aatgtccatc tctatcacat agttcaaaga
1921 gaaggaggat gggatgctgt tatggactgg aaagatgtcc tgtcaggagg ggaaaagcaa
1981 agaatgggca tggctcgtat gttttatcat aaaccaaaat atgccttgct ggatgaatgt
2041 accagtgctg tcagcattga tgtcgaagga aagatatttc aggctgcaaa aggggctgga
2101 atttccttac tgtctataac acacagacct tctctttgga aataccacac acatttatta
2161 cagtttgatg gtgaaggagg ttggcgcttt gaacaattgg atactgctat ccgtttgaca
2221 ttgagtgaag aaaaacaaaa gctagaatct cagctagctg gaattcccaa aatgcagcag
2281 agactcaatg aactatgtaa aattttggga gaagactcag tgctgaaaac aattaaaaat
2341 gaagatgaga catcttaatt tgttttgaca tattttaaaa agttaattat tagataaagg
2401 ctcaaagaca ttctgttata ctgcatgaag tatgttaagc taagcacaga gaaaaaaagg
2461 cagcaagaca tgttttataa gattttagca ttaaggaagt atatgatctg acttttcaga
2521 agaaaataaa caaatgcatt atgtaaggtc agtcattatg acttatacta attcctagtg
2581 aaggcctaat gcacttgtaa aacaggattt tctaggtgaa ttcctgatga ataccagatt
2641 tactatgtat atgtggtgtg tctgaagttc ttaacaaaca tgggcaatat tctggaaatg
2701 aaacaagtta taactgagca ccatttgggt tgataccaag tgcataagat tcaaactttg
2761 agtgacattt agtccattta tggttgatat taggtttaat acctagaatt caaattgatt
2821 attgctagtg gccaactaaa cctgtacaaa atagctgaca gttttataac taatttcaat
2881 ataaaaattg ttttaatggc atttgttgaa agaaaaaagc atggctaaaa tgtatcaaat
2941 gccntatttt taaattttgg actttaagca tcttaatgag ggcatataac aaattaattt
3001 tagtacaatc ttaaatattt ttaataaatc ctttcatttt aaaaagagaa ttgccaatac
3061 agaaaaggag tatccaaaca atgtctcaac ctgataattt ccttagcaga attacctatt
3121 gcaacttctg ttcagaaata cacagcttgt ttttttgccc aaggatgagt ctacatttta
3181 agaactgcaa tggtataaag gaacttaagg attctgagaa tcatagtaat aacatacatt
3241 ggaatagtac tttataattt acaatcccca tttacatcat ttcaccttaa tgttgaggac
3301 aatgttttga aacaaatact atttttccta ctttgctttt gagaaaattg acactcagac
3361 ttgccctaat catgcacttt acttaaggaa agatcgagaa atcaaatgaa gttctcctga
3421 ctctctggtt tagtgctctt ttgttattat cctttaaatc aaactgggct ataatagcaa
3481 taaaagttag acgaagtgta gaaaataaaa taaatttcat aatgttaaaa aaaaaaaaaa
3541 aaaaaaa
//