LOCUS AF549455 3690 bp mRNA linear HUM 28-OCT-2003
DEFINITION Homo sapiens BIG-2 (BIG-2) mRNA, complete cds.
ACCESSION AF549455
VERSION AF549455.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3690)
AUTHORS Hansford,L.M., Smith,S.A., Haber,M., Norris,M.D., Cheung,B. and
Marshall,G.M.
TITLE Cloning and characterization of the human neural cell adhesion
molecule, CNTN4 (alias BIG-2)
JOURNAL Cytogenet. Genome Res. 101 (1), 17-23 (2003)
PUBMED 14571131
REFERENCE 2 (bases 1 to 3690)
AUTHORS Hansford,L.M., Smith,S.A., Cheung,B. and Marshall,G.M.
TITLE Direct Submission
JOURNAL Submitted (03-OCT-2002) Molecular Carcinogenesis, Children's Cancer
Institute Australia for Medical Research, High Street, PO Box 81,
Randwick, NSW 2031, Australia
FEATURES Location/Qualifiers
source 1..3690
/db_xref="H-InvDB:HIT000081516"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3690
/gene="BIG-2"
/note="hBIG-2"
5'UTR 1..382
/gene="BIG-2"
CDS 383..3463
/gene="BIG-2"
/note="AxCAM; Contactin 4; Ig-superfamily of molecules"
/codon_start=1
/product="BIG-2"
/protein_id="AAP05786.1"
/translation="MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEK
KVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTA
TNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFN
EYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDG
VMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKS
NGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVF
WECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGV
IFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKE
NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMD
VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNI
QLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNH
SPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGI
GEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFR
PYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAE
EEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV
GNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSD
SKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEI
KPFSDGGDGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL"
3'UTR 3464..3690
/gene="BIG-2"
BASE COUNT 1192 a 765 c 838 g 895 t
ORIGIN
1 gccattctcc tgcctcagct cccgagaagc tgggactaca ggcgcccgcc accacgcccg
61 gctcattttt tgtattttta gtagagacgg gtttcaccgt gttagccagg attgtctcga
121 tctcctgacc tcatgatccg cccgcctcgg cctcccaaag tgctgggatt acaggcgtga
181 gccaccgccc ggcctggctc tgtttttatt agaaaaattc tcaatcgtcg tcttttaaga
241 atcattgaca tagagtaact ccacagcatg tgtcttcaag agcttcccta aaagattaaa
301 ggttatacaa aacttaaaag aagcagcaat tctattcgct tgttattgga cttgaaactc
361 cctttgacct cggaaactga agatgaggtt gccatgggaa ctgctggtac tgcaatcatt
421 cattttgtgc cttgcagatg attccacact gcatggcccg atttttattc aagaaccaag
481 tcctgtaatg ttccctttgg attctgagga gaaaaaagtg aagctcaatt gtgaagttaa
541 aggaaatcca aaacctcata tcaggtggaa gttaaatgga acagatgttg acactggtat
601 ggatttccgc tacagtgttg ttgaagggag cttgttgatc aataacccca ataaaaccca
661 agatgctgga acgtaccagt gcacagcgac aaactcgttt ggaacaattg ttagcagaga
721 agcaaagctt cagtttgctt atcttgacaa ctttaaaaca agaacaagaa gcactgtgtc
781 tgtccgtcga ggtcaaggaa tggtgctact gtgtggcccg ccaccccatt ctggagagct
841 gagttatgcc tggatcttca atgaataccc ttcctatcag gataatcgcc gctttgtttc
901 tcaagagact gggaatctgt atattgccaa agtagaaaaa tcagatgttg ggaattatac
961 ctgtgtggtt accaataccg tgacaaacca caaggtcctg gggccaccta caccactaat
1021 attgagaaat gatggagtga tgggtgaata tgagcccaaa atagaagtgc agttcccaga
1081 aacagttccg actgcaaaag gagcaacggt gaagctggaa tgctttgctt taggaaatcc
1141 agtaccaact attatctggc gaagagctga tggaaagcca atagcaagga aagccagaag
1201 acacaagtca aatggaattc ttgagatccc taattttcag caggaggatg ctggtttata
1261 tgaatgtgta gctgaaaatt ccagagggaa aaatgtagca aggggacagc taactttcta
1321 tgctcaacct aattggattc aaaaaataaa tgatattcac gtggccatgg aagaaaatgt
1381 cttttgggaa tgtaaagcaa atggaaggcc taagcctaca tacaagtggc taaaaaatgg
1441 cgaacctctg ctaactcggg atagaattca aattgagcaa ggaacactca acataacaat
1501 agtgaacctc tcagatgctg gcatgtatca gtgtttggca gagaataaac atggagttat
1561 cttttccaac gcagagctta gtgttatagc tgtaggtcca gatttttcaa gaacactctt
1621 gaaaagagta actcttgtca aagtgggagg tgaagttgtc attgagtgta agccaaaagc
1681 gtctccaaaa cctgtttaca cctggaagaa aggaagggat atattaaaag aaaatgaaag
1741 aattaccatt tctgaagatg gaaacctcag aatcatcaac gttactaaat cagacgctgg
1801 gagttatacc tgtatagcca ctaaccattt tggaactgct agcagtactg gaaacttggt
1861 agtgaaagat ccaacaaggg taatggtacc cccttccagt atggatgtca ctgttggaga
1921 gagtattgtt ttaccgtgcc aggtaacgca tgatcactcg ctagacatcg tgtttacttg
1981 gtcatttaat ggacacctga tagactttga cagagatggg gaccactttg aaagagttgg
2041 agggcaggat tcagctggtg atttgatgat ccgaaacatc caactgaagc atgctgggaa
2101 atatgtctgc atggtccaaa caagtgtgga caggctatct gctgctgcag acctgattgt
2161 aagaggtcct ccaggtcccc cagaggctgt gacaatagac gaaatcacag ataccactgc
2221 tcagctctcc tggagacccg ggcctgacaa ccacagcccc atcaccatgt atgtcattca
2281 agccaggact ccattctccg tgggctggca agcagtcagt acagtcccag aactcattga
2341 tgggaagaca ttcacagcga ccgtggtggg tttgaaccct tgggttgaat atgaattccg
2401 cacagttgca gccaacgtga ttgggattgg ggagcccagc cgcccctcag agaaacggag
2461 aacagaagaa gctctccccg aagtcacacc agcgaatgtc agtggtggcg gaggcagcaa
2521 atctgaactg gttataacct gggagacggt ccctgaggaa ttacagaatg gtcgaggctt
2581 tggttatgtg gtggccttcc ggccctacgg taaaatgatc tggatgctga cagtgctggc
2641 ctcagctgat gcctctagat acgtgttcag gaatgagagc gtgcacccct tctctccctt
2701 tgaggttaaa gtaggtgtct tcaacaacaa aggagaaggc cctttcagtc ccaccacggt
2761 ggtgtattct gcagaagaag aacccaccaa accaccagcc agtatctttg ccagaagtct
2821 ttctgccaca gatattgaag ttttctgggc ctccccactg gagaagaata gaggacgaat
2881 acaaggttat gaggttaaat attggagaca tgaagacaaa gaagaaaatg ctagaaaaat
2941 acgaacagtt ggaaatcaga catcaacaaa aatcacgaac ttaaaaggca gtgtgctgta
3001 tcacttagct gtcaaggcat ataattctgc tgggacaggc ccctctagtg caacagtcaa
3061 tgtgacaacc cgaaagccac caccaagtca accccccgga aacatcatat ggaattcatc
3121 agactccaaa attatcctga attgggatca agtgaaggcc ctggataatg agtcggaagt
3181 aaaaggatac aaagtcttgt acagatggaa cagacaaagc agcacatctg tcattgaaac
3241 aaataaaaca tcggtggagc tttctttgcc tttcgatgaa gattatataa tagaaattaa
3301 gccattcagc gacggaggag atggcagcag cagtgaacaa attcgaattc caaagatatc
3361 aaatgcctac gcgagaggat ctggggcttc cacttcgaat gcatgtacgc tgtcagccat
3421 cagtacaata atgatttccc tcacagctag gtccagttta tgacaaaagt tatctgaagg
3481 acttgctgtt tataatataa gcaacattta gctagttgtt ttgaagacac ccagtactaa
3541 gtaatattgt tgttcaagta catcttatta ctggaataaa aatgtttttt gcttctttaa
3601 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3661 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//