LOCUS AF536976 2407 bp mRNA linear HUM 24-JUL-2003
DEFINITION Homo sapiens cAMP-specific phosphodiesterase PDE4D7 (PDE4D) mRNA,
complete cds; alternatively spliced.
ACCESSION AF536976
VERSION AF536976.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2407)
AUTHORS Wang,D., Deng,C., Bugaj-Gaweda,B., Kwan,M., Gunwaldsen,C.,
Leonard,C., Xin,X., Hu,Y., Unterbeck,A. and De Vivo,M.
TITLE Cloning and characterization of novel PDE4D isoforms PDE4D6 and
PDE4D7
JOURNAL Cell. Signal. 15 (9), 883-891 (2003)
PUBMED 12834813
REFERENCE 2 (bases 1 to 2407)
AUTHORS Wang,D., Bugaj-Gaweda,B., Kwan,M., Xin,X., Leonard,C., Unterbeck,A.
and De Vivo,M.
TITLE Direct Submission
JOURNAL Submitted (12-AUG-2002) Discovery Research, Memory Pharmaceuticals
Corp., 100 Philips Parkway, Montvale, NJ 07645, USA
FEATURES Location/Qualifiers
source 1..2407
/db_xref="H-InvDB:HIT000081434"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
gene 1..2407
/gene="PDE4D"
CDS 70..2316
/gene="PDE4D"
/note="alternatively spliced"
/codon_start=1
/product="cAMP-specific phosphodiesterase PDE4D7"
/protein_id="AAN10118.1"
/translation="MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCR
NIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILPLIAITSAESSGFDVDNGTSAGR
SPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASE
TLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTF
LDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLA
KELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLED
HYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSN
QFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDI
VLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWET
WADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEED
GESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACV
IDDRSPDT"
BASE COUNT 718 a 552 c 534 g 603 t
ORIGIN
1 agtggatcgt gcagtgagat cttgacattg gaaacactag ttcccatttt aattacttaa
61 aacaccacga tgaaaagaaa tacctgtgat ttgctttctc ggagcaaaag tgcctctgag
121 gaaacactac attccagtaa tgaagaggaa gaccctttcc gcggaatgga accctatctt
181 gtccggagac tttcatgtcg caatattcag cttccccctc tcgccttcag acagttggaa
241 caagctgact tgaaaagtga atcagagaac attcaacgac caaccagcct ccccctgaag
301 attctgccgc tgattgctat cacttctgca gaatccagtg gttttgatgt ggacaatggc
361 acatctgcgg gacggagtcc cttggatccc atgaccagcc caggatccgg gctaattctc
421 caagcaaatt ttgtccacag tcaacgacgg gagtccttcc tgtatcgatc cgacagcgat
481 tatgacctct ctccaaagtc tatgtcccgg aactcctcca ttgccagtga tatacacgga
541 gatgacttga ttgtgactcc atttgctcag gtcttggcca gtctgcgaac tgtacgaaac
601 aactttgctg cattaactaa tctgcaagat cgagcaccta gcaaaagatc acccatgtgc
661 aaccaaccat ccatcaacaa agccaccata acagaggagg cgtaccagaa actggccagc
721 gagaccctgg aggagctgga ctggtgtctg gaccagctag agaccctaca gaccaggcac
781 tccgtcagtg agatggcctc caacaagttt aaaaggatgc ttaatcggga gctcacccat
841 ctctctgaaa tgagtcggtc tggaaatcaa gtgtcagagt ttatatcaaa cacattctta
901 gataagcaac atgaagtgga aattccttct ccaactcaga aggaaaagga gaaaaagaaa
961 agaccaatgt ctcagatcag tggagtcaag aaattgatgc acagctctag tctgactaat
1021 tcaagtatcc caaggtttgg agttaaaact gaacaagaag atgtccttgc caaggaacta
1081 gaagatgtga acaaatgggg tcttcatgtt ttcagaatag cagagttgtc tggtaaccgg
1141 cccttgactg ttatcatgca caccattttt caggaacggg atttattaaa aacatttaaa
1201 attccagtag atactttaat tacatatctt atgactctcg aagaccatta ccatgctgat
1261 gtggcctatc acaacaatat ccatgctgca gatgttgtcc agtctactca tgtgctatta
1321 tctacacctg ctttggaggc tgtgtttaca gatttggaga ttcttgcagc aatttttgcc
1381 agtgcaatac atgatgtaga tcatcctggt gtgtccaatc aatttctgat caatacaaac
1441 tctgaacttg ccttgatgta caatgattcc tcagtcttag agaaccatca tttggctgtg
1501 ggctttaaat tgcttcagga agaaaactgt gacattttcc agaatttgac caaaaaacaa
1561 agacaatctt taaggaaaat ggtcattgac atcgtacttg caacagatat gtcaaaacac
1621 atgaatctac tggctgattt gaagactatg gttgaaacta agaaagtgac aagctctgga
1681 gttcttcttc ttgataatta ttccgatagg attcaggttc ttcagaatat ggtgcactgt
1741 gcagatctga gcaacccaac aaagcctctc cagctgtacc gccagtggac ggaccggata
1801 atggaggagt tcttccgcca aggagaccga gagagggaac gtggcatgga gataagcccc
1861 atgtgtgaca agcacaatgc ttccgtggaa aaatcacagg tgggcttcat agactatatt
1921 gttcatcccc tctgggagac gtgggcagac ctcgtccacc ctgacgccca ggatattttg
1981 gacactttgg aggacaatcg tgaatggtac cagagcacaa tccctcagag cccctctcct
2041 gcacctgatg acccagagga gggccggcag ggtcaaactg agaaattcca gtttgaacta
2101 actttagagg aagatggtga gtcagacacg gaaaaggaca gtggcagtca agtggaagaa
2161 gacactagct gcagtgactc caagactctt tgtactcaag actcagagtc tactgaaatt
2221 ccccttgatg aacaggttga agaggaggca gtaggggaag aagaggaaag ccagcctgaa
2281 gcctgtgtca tagatgatcg ttctcctgac acgtaacagt gcaaaaactt tcatgccttt
2341 ttttttttaa gtagaaaaat tgtttccaaa gtgcattgtc acatgcccaa ccacggtcaa
2401 cctactg
//