LOCUS AF536975 1861 bp mRNA linear HUM 24-JUL-2003
DEFINITION Homo sapiens cAMP-specific phosphodiesterase PDE4D6 (PDE4D) mRNA,
complete cds; alternatively spliced.
ACCESSION AF536975
VERSION AF536975.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1861)
AUTHORS Wang,D., Deng,C., Bugaj-Gaweda,B., Kwan,M., Gunwaldsen,C.,
Leonard,C., Xin,X., Hu,Y., Unterbeck,A. and De Vivo,M.
TITLE Cloning and characterization of novel PDE4D isoforms PDE4D6 and
PDE4D7
JOURNAL Cell. Signal. 15 (9), 883-891 (2003)
PUBMED 12834813
REFERENCE 2 (bases 1 to 1861)
AUTHORS Wang,D., Bugaj-Gaweda,B., Kwan,M., Xin,X., Leonard,C., Unterbeck,A.
and De Vivo,M.
TITLE Direct Submission
JOURNAL Submitted (12-AUG-2002) Discovery Research, Memory Pharmaceuticals
Corp., 100 Philips Parkway, Montvale, NJ 07645, USA
FEATURES Location/Qualifiers
source 1..1861
/db_xref="H-InvDB:HIT000081433"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
gene 1..1861
/gene="PDE4D"
CDS 204..1760
/gene="PDE4D"
/note="alternatively spliced"
/codon_start=1
/product="cAMP-specific phosphodiesterase PDE4D6"
/protein_id="AAN10117.1"
/translation="MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISN
TFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDV
LAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVI
DIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW
ETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLE
EDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEA
CVIDDRSPDT"
BASE COUNT 579 a 375 c 404 g 503 t
ORIGIN
1 catgtattcg atgggaagac ggctggatgg gatttaatgc gaggctttct tatgtatact
61 taattaccaa aaatctttaa aaactcatac tctgcgtggc ttgtggaggt tgttaaagtg
121 tcgagatttt gaagctaaat acattttaga gcttactata tatatacata tacatatata
181 tatatacata taatcaatca aaaatgcctg aagcaaacta tttactgtca gtgtcttggg
241 gctacataaa gtttaaaagg atgcttaatc gggagctcac ccatctctct gaaatgagtc
301 ggtctggaaa tcaagtgtca gagtttatat caaacacatt cttagataag caacatgaag
361 tggaaattcc ttctccaact cagaaggaaa aggagaaaaa gaaaagacca atgtctcaga
421 tcagtggagt caagaaattg atgcacagct ctagtctgac taattcaagt atcccaaggt
481 ttggagttaa aactgaacaa gaagatgtcc ttgccaagga actagaagat gtgaacaaat
541 ggggtcttca tgttttcaga atagcagagt tgtctggtaa ccggcccttg actgttatca
601 tgcacaccat ttttcaggaa cgggatttat taaaaacatt taaaattcca gtagatactt
661 taattacata tcttatgact ctcgaagacc attaccatgc tgatgtggcc tatcacaaca
721 atatccatgc tgcagatgtt gtccagtcta ctcatgtgct attatctaca cctgctttgg
781 aggctgtgtt tacagatttg gagattcttg cagcaatttt tgccagtgca atacatgatg
841 tagatcatcc tggtgtgtcc aatcaatttc tgatcaatac aaactctgaa cttgccttga
901 tgtacaatga ttcctcagtc ttagagaacc atcatttggc tgtgggcttt aaattgcttc
961 aggaagaaaa ctgtgacatt ttccagaatt tgaccaaaaa acaaagacaa tctttaagga
1021 aaatggtcat tgacatcgta cttgcaacag atatgtcaaa acacatgaat ctactggctg
1081 atttgaagac tatggttgaa actaagaaag tgacaagctc tggagttctt cttcttgata
1141 attattccga taggattcag gttcttcaga atatggtgca ctgtgcagat ctgagcaacc
1201 caacaaagcc tctccagctg taccgccagt ggacggaccg gataatggag gagttcttcc
1261 gccaaggaga ccgagagagg gaacgtggca tggagataag ccccatgtgt gacaagcaca
1321 atgcttccgt ggaaaaatca caggtgggct tcatagacta tattgttcat cccctctggg
1381 agacatgggc agacctcgtc caccctgacg cccaggatat tttggacact ttggaggaca
1441 atcgtgaatg gtaccagagc acaatccctc agagcccctc tcctgcacct gatgacccag
1501 aggagggccg gcagggtcaa actgagaaat tccagtttga actaacttta gaggaagatg
1561 gtgagtcaga cacggaaaag gacagtggca gtcaagtgga agaagacact agctgcagtg
1621 actccaagac tctttgtact caagactcag agtctactga aattcccctt gatgaacagg
1681 ttgaagagga ggcagtaggg gaagaagagg aaagccagcc tgaagcctgt gtcatagatg
1741 atcgttctcc tgacacgtaa cagtgcaaaa actttcatgc cttttttttt taagtagaaa
1801 aattgtttcc aaagtgcatg tcacatgcca caaccacggt cacacctcac tgtcatctgc
1861 c
//