LOCUS AF534403 6585 bp mRNA linear HUM 31-JUL-2003
DEFINITION Homo sapiens c-MYC promoter-binding protein IRLB (IRLB) mRNA,
complete cds.
ACCESSION AF534403
VERSION AF534403.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6585)
AUTHORS Semova,N., Kapanadze,B., Corcoran,M., Kutsenko,A., Baranova,A. and
Semov,A.
TITLE Molecular cloning, structural analysis, and expression of a human
IRLB, MYC promoter-binding protein: new DENN domain-containing
protein family emerges small star, filled
JOURNAL Genomics 82 (3), 343-354 (2003)
PUBMED 12906859
REFERENCE 2 (bases 1 to 6585)
AUTHORS Semov,A., Kapanadze,B. and Semova,N.
TITLE Direct Submission
JOURNAL Submitted (05-AUG-2002) Gene Discovery, Supratek Pharma, 531, Blvd.
des Prairies, Bldg. 18, Laval, QC H7V 1B7, Canada
FEATURES Location/Qualifiers
source 1..6585
/db_xref="H-InvDB:HIT000243746"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q22"
/cell_type="fibroblasts"
gene 1..6585
/gene="IRLB"
CDS 341..5938
/gene="IRLB"
/codon_start=1
/product="c-MYC promoter-binding protein IRLB"
/protein_id="AAQ10514.1"
/translation="MIEDKGPRVADYFVVAGLTDVSKPLEEEIHFNDACHKVAKPKEP
ITDVSVIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTD
LGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTD
ICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQ
EDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFY
EPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYR
YSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGK
FSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVP
LCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKIL
PKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAF
LFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQM
FIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGEVRLIELDESFKSEHTVFVTPPEI
PHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTK
QEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLK
KMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVL
ESTWPSRSRSGYFLWTKVRNVVLGVTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKD
EVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSN
NSAGKISGESMGKESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWG
NRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPP
LRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPK
RIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARR
DLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPV
RLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDV
LRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDV
CHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASN
TNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLN
IEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDL
NSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTG
SLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVD
HHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDN
MKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQ
ILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKST
HNCDRPPSTGVMECRKTFGEPYL"
BASE COUNT 2061 a 1269 c 1352 g 1903 t
ORIGIN
1 ggagaaagag gcggaggcag tggcggccgc gaggggaggg ggagtcccgt ctgactgaga
61 cggcaggcct gggcgggcgg gcgggggtgc cgcgaagggc ggagcgccgg gctggggatg
121 agctaagcgg gctcagagcg ccgcggcatt cagcccctcg tgttccgcta ccgcgcgtgc
181 gggattccgg cgccgctctc cgagctcgat ccgctgctcg cacgggagcc agctgggtgt
241 tatttctcaa actctgaggc tgcggagttc acacattgaa atctgtcatc tttttcagag
301 agaaactttc ggtaatgtat gtaaccttct gtaatggaag atgattgaag acaaggggcc
361 tcgtgttgct gactactttg ttgtagcagg attaactgat gtttcaaagc ctctagaaga
421 agaaattcac ttcaatgatg cttgtcataa agtagctaaa ccaaaagaac ctattacaga
481 tgtttcagtt attatcaaat ctcttgggga ggaagtccca caggattata tctgtattga
541 tgttacccca actggattgt cagctgatct taataatgga agtcttgtgg ggccacagat
601 ttacctttgc tatagaagag gaagagataa gcctccactt acagatctgg gggttttata
661 tgactggaaa gaaagattga aacagggttg tgaaattatt cagagtactc cctatgggcg
721 ccccgcaaat attagtggga gtacctcatc acaaagaatt tatatcactt accgaagagc
781 ctctgaaaac atgactcaga atacgttggc tgtcactgac atatgtatta ttatacccag
841 taaaggagaa agcccaccac acacgttctg caaagtcgac aagaatctca ataacagtat
901 gtggggatca gcagtatact tgtgttataa aaaatcggtg gcaaagacga acactgtatc
961 ttacaaagct ggcctaattt gtagatatcc tcaagaagat tatgagtcat tctcactacc
1021 ggaatctgtt cctctatttt gtttaccaat gggtgcaacc attgaatgtt ggccatcaaa
1081 tagcaaatac cctctgcctg tattttctac ttttgtttta actggagcct cagctgaaaa
1141 ggtttatggt gctgctattc agttttatga accatactct gaggagaatc tcacagaaaa
1201 gcagagactt cttttgggtt taacatcagc agatgggaag tctgatagtt ccaaaacaat
1261 tcatactaac aaatgcatct gtcttctttc tcactggcct ttttttgatg cattcaggaa
1321 gtttctgact tttctgtatc gttattccat ctctgggcct catgtccttc caattgagaa
1381 gcatatttct cattttatgc ataaagttcc ttttccatct cctcagagac cacggatttt
1441 agttcagtta tcaccacatg ataatctgat tctcagtcag cctgtgtctt cacctcttcc
1501 actaagtggt ggcaagtttt caacactact gcagaattta ggccctgaaa atgctgtgac
1561 actactggtg tttgcagtaa cagaacataa aattcttatc cattccctac ggccatccgt
1621 gcttactagt gtgacagaag cattagtgtc tatgattttc cctttccact ggccatgccc
1681 gtatgttcct ctctgcccac tggctttagc agatgtcttg agtgcaccat gtccattcat
1741 agtagggatt gattcaagat actttgatct ctatgatcct ccaccagatg tcagttgtgt
1801 tgatgtagat accaacacta tttctcagat tggtgacaag aaaaatgtag cctggaagat
1861 acttccaaag aagccatgta aaaatctgat gaacacactg aataatttgc atcagcaatt
1921 ggcaaaattg cagcagagac cgagagatga tggactcatg gatttagcaa taaatgacta
1981 tgattttaat tctggaaaga ggttgcacat gatagatttg gaaatccaag aggcattttt
2041 gtttttcatg gcctctattt taaaaggtta cagatcatac ttaaggccaa taacacaagc
2101 cccatctgag acagccacag atgcagcctc tctctttgcc ctacaagctt tcttaagaag
2161 ccgggaccgg tcacatcaaa aattctataa catgatgacc aaaacacaaa tgtttattcg
2221 cttcattgaa gaatgttctt ttgttagtga caaagatgca agcctggcat tttttgatga
2281 ttgtgtagat aaagtggata tggacaagag cggtgaagta cgacttatag aactggatga
2341 atctttcaaa agtgaacaca ctgtttttgt aacaccacct gagatccccc acctacccaa
2401 tggtgaagaa ccccctttac agtacagcta taatggattt ccagttctta ggaacaattt
2461 atttgaaaga cctgaaggat ttctacaagc aaagaagaac aaattgcctt caaaatcaag
2521 tagtcctaat agccctttgc ccatgttcag aagaacaaaa caggaaatta aatcagccca
2581 taaaattgca aagaggtact cttccatccc tcagatgtgg tctaggtgtc tactgcgcca
2641 ctgttatgga ctgtggttta tttgtctccc agcttatgtg aaagtctgtc attcaaaagt
2701 cagggctctg aaaacagcat atgatgtgct taaaaaaatg cagtcaaaga agatggatcc
2761 acctgatgag gtatgctacc gcattcttat gcaactctgt ggacaatatg atcagccagt
2821 gcttgcagtt cgagtgcttt ttgaaatgca gaaagctggt attgacccca atgccattac
2881 ttatggttat tataataagg ctgttttgga aagtacctgg ccttcaagaa gtcgtagtgg
2941 ctattttctt tggacaaaag taagaaatgt tgttttagga gtaacacagt tcaaaagagc
3001 tttaaagaag catgcacact tatcacaaac aactctctca ggtggccagt ctgatcttgg
3061 atataattca ttatctaaag atgaagttag aagaggggat acatctactg aagacattca
3121 agaagaaaaa gataaaaaag ggagtgattg tagttccttg tcagagagtg agagtacaaa
3181 aggaagtgct gattgccttc ctaagctcag ttatcaaaat tcttccagta tcgttcgcct
3241 cactggtaca agtaacaaca gtgctggtaa aatatcagga gaaagcatgg gtaaggaaag
3301 cacacctgag ctgctcttaa tatcatctct tgaagataca aatgaaacac gaaacattca
3361 aagtagatgc ttcaggaaaa gacataaaag tgacaatgaa actaatttgc agcagcaagt
3421 ggtctgggga aatagaaacc gtaatcttag tggaggggta ctgatgggat ttatgctcaa
3481 tagaattaac caggaagcaa cccctggaga tatagttgaa aaattgggag ctgatgcaaa
3541 aattctttca aatgttatct caaaaagcac gagaccaaat actcttgata ttgggaagcc
3601 acctttaaga tcaaaaagag acagtctaga aaaggaatct agtgatgatg atacaccttt
3661 tgatggttct aactatttgg cagataaagt ggattctcct gttatttttg acttagaaga
3721 cttagacagt gaaacagatg tatcaaaagc aggatgtgtt gctacacaaa atcccaagag
3781 gattcaacgt atgaacagca gcttttcagt aaaacctttt gaaaaaactg atgtcgcaac
3841 aggatttgat cccctctctc ttttggttgc tgagactgaa cagcagcaaa aagaagaaga
3901 ggaggaggat gaagatgata gcaaaagcat ttcaacacca tctgctaggc gtgatttagc
3961 tgaagaaatt gtgatgtata tgaataacat gagcagtcct ttgacaagtc gtacaccaag
4021 cattgattta caacgggcat gtgatgataa attaaataag aaaagtccac cattggtcaa
4081 ggcatgcaga agatctagtc tgcctcctaa ttctcctaag ccagtgagac ttaccaaatc
4141 taaaagttac acaaaaagtg aggagaaacc aagggataga ctttggtctt ctccagcctt
4201 ctcacctact tgcccattta gggaagaatc tcaggataca ttaacccact catcaccttc
4261 atttaactta gatacactac tagtacctaa actagatgtt ctaagaaaca gtatgttcac
4321 tgctggaaaa ggagttgcag agaaagcaag caaatggtat tcaagattca ccatgtacac
4381 cacatcatct aaggatcaaa gttctgatcg taccagtctt tcttcagtgg gagcccagga
4441 ttctgaatct acctctttaa cagatgaaga tgtctgccat gagttggaag gacctatctc
4501 ctctcaagag accagtgcta cttcagggac taagagaatt gatctcagcc gaataagcct
4561 ggaaagttct gcatccttgg aaggatctct gtcgaagttt gccttacctg ggaaatcaga
4621 agtgacatct tccttcaacg cgagtaatac aaatatcttc cagaactatg caatggaggt
4681 tctcatctca agttgctctc ggtgtagaac ttgtgattgt cttgtccatg atgaggaaat
4741 catggctggc tggacagcag atgattcaaa tctcaatact acatgcccat tctgtggcaa
4801 tatcttctta ccctttctga atatagaaat aagagattta agacgacctg gaagatactt
4861 tctaaagtca agcccatcaa cagaaaatat gcactttcca tcctccattt caagtcagac
4921 gaggcagtct tgcatttcaa catcagcctc tggtcttgac acatctgctc tctctgttca
4981 agggaatttt gatctaaata gcaaatctaa actgcaggaa aatttttgca cccgaagtat
5041 tcagatccct gctaatagat caaaaacagc tatgtctaaa tgtccaatat ttccaatggc
5101 caggagtatt agtacttctg gccccttgga taaggaagat actggaagac agaagctcat
5161 ttctacaggc agcctgccag ctactttaca aggagctaca gattctttag gtttagaatg
5221 gcaccttcca agtcccgatc ctgtcactgt tccgtatctt agtcctttag tggtatggaa
5281 agaacttgaa agcttattgg aaaatgaagg tgatcatgca ataacagtag cagactttgt
5341 ggaccatcat ccaattgttt tttggaacct ggtatggtat ttcagacgtc ttgacttgcc
5401 cagtaactta cctggattga ttctttcttc tgagcactgt aacaagtatt caaagattcc
5461 ccgccactgt atgtctgaag atagcaaata tgttttaata caaatgttat gggacaatat
5521 gaagttacat caggatccgg gacagccctt gtacattctc tggaatgcac acacccaaaa
5581 atatccaatg gtccatttat tgcaaaaaag tgataactca tttaaccagg aactgttgaa
5641 aagtatggta aaaagcatta aaatgaatga tgtctatgga ccaatgagtc agattttaga
5701 gacactgaat aagtgtccac attttaaaag acagaggagt ttatacagag aaatactatt
5761 tctctcactt gtggcactgg gaagagaaaa cattgatata gatgcttttg ataaagagta
5821 caagatggca tacgatcgtc tcacacctag tcaagtcaag agtacacaca actgtgatag
5881 accaccaagt acaggggtga tggaatgtcg aaaaaccttt ggagaacctt atctttaaga
5941 tgtatttgta tgtgtaaaca ttcaatgtat attgtatagt cagtgtataa aataacactt
6001 ttagactcta aatatttttt cttcaatttt tgaaaataca atttgtaaat ggttcaaaag
6061 actcagacag cttatgtaca gaatgtttga agaagagaat agtgacaagt ggggagaaag
6121 ccactttgtt tctcatttct tttttcttct tctttaactc ccctgtaata ggaaataaag
6181 tatttttgtg atgaggaaat ccctaaacaa aattagttgc cataaaatat gacaactgct
6241 ttatggtttc ttttggaaga gacagattga aaaatcatga atggaatcta aacagaaatg
6301 tcagatgaac gtatttcctg ttttcataga ctattcaaat gttttgacca tgaagttgta
6361 ttatacatat tttaaattgt ttatagtaag ttgatatttt tttaattttt aaatttaata
6421 tagcaaactt aaaatgaatt taaacttaag caagcaagcg tgtattttcc ttgtctgctg
6481 ctatttgaag taattagtac agctgcagat ctctctgtgt atatctatct atatatatat
6541 tttttattac ttgggagaat gaattttaaa atgtcagtgc tagtg
//