LOCUS AF521882 8120 bp mRNA linear HUM 22-DEC-2003
DEFINITION Homo sapiens multiple ankyrin repeats single KH domain protein
isoform 1 mRNA, complete cds, alternatively spliced.
ACCESSION AF521882
VERSION AF521882.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8120)
AUTHORS Poulin,F., Brueschke,A. and Sonenberg,N.
TITLE Gene fusion and overlapping reading frames in the mammalian genes
for 4E-BP3 and MASK
JOURNAL J. Biol. Chem. 278 (52), 52290-52297 (2003)
PUBMED 14557257
REFERENCE 2 (bases 1 to 8120)
AUTHORS Poulin,F. and Sonenberg,N.
TITLE Direct Submission
JOURNAL Submitted (15-JUN-2002) Biochemistry, McGill University, 3655
Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada
FEATURES Location/Qualifiers
source 1..8120
/db_xref="H-InvDB:HIT000081204"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q31"
CDS 61..7689
/note="MASK"
/codon_start=1
/product="multiple ankyrin repeats single KH domain
protein isoform 1"
/protein_id="AAO14943.1"
/translation="MLTDSGGGGTSFEEDLDSVAPRSAPAGASEPPPPGGVGLGIRTV
RLFGEAGPASGVGSSGGGGSGSGTGGGDAALDFKLAAAVLRTGGGGGASGSDEDEVSE
VESFILDQEDLDNPVLKTTSEIFLSSTAEGADLRTVDPETQARLEALLEAAGIGKLST
ADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAENSHNAGQVDTRSLAEACSDGDV
NAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPL
MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDH
NENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLL
EAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGH
VELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETA
LTLACCGGFSEVADFLIKAGADIELGCSTPLMEASQEGHLELVKYLLASGANVHATTA
TGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKG
ANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTN
VVSYLLDYPNNVLSVPTTDVSQLPPPSQDQSQVPRVPTHTLAMVVPPQEPDRTSQENS
PALLGVQKGTSKQKSSSLQVADQDLLPSFHPYQPLECIVEETEGKLNELGQRISAIEK
AQLKSLELIQGEPLNKDKIEELKKNREEQVQKKKKILKELQKVERQLQMKTQQQFTKE
YLETKGQKDTVSLHQQCSHRGVFPEGEGDGSLPEDHFSELPQVDTILFKDNDVDDEQQ
SPPSAEQIDFVPVQPLSSPQCNFSSDLGSNGTNSLELQKVSGNQQIVGQPQIAITGHD
QGLLVQEPDGLMVATPAQTLTDTLDDLIAAVSTRVPTGSNSSSQTTECLTPESCSQTT
SNVASQSMPPVYPSVDIDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKG
FTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA
NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVP
AVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLM
EAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDV
RNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLV
KEVNQFPSDIECMRYIATITDKELLKKCHQCVETIVKAKDQQAAEANKNASILLKELD
LEKSREESRKQALAAKREKRKEKRKKKKEEQKRKQEEDEENKPKENSELPEDEDEEEN
DEDVEQEVPIEPPSATTTTTIGISATSATFTNVFGKKRANVVTTPSTNRKNKKNKTKE
TPPTAHLILPEQHMSLAQQKADKNKINGEPRGGGAGGNSDSDNLDSTDCNSESSSGGK
SQELNFVMDVNSSKYPSLLLHSQEEKTSTATSKTQTRLEGEVTPNSLSTSYKTVSLPL
SSPNIKLNLTSPKRGQKREEGWKEVVRRSKKLSVPASVVSRIMGRGGCNITAIQDVTG
AHIDVDKQKDKNGERMITIRGGTESTRYAVQLINALIQDPAKELEDLIPKNHIRTPAS
TKSIHANFSSGVGTTAASSKNAFPLGAPTLVTSQATTLSTFQPANKLNKNVPTNVRSS
FPVSLPLAYPHPHFALLAAQTMQQIRHPRLPMAQFGGTFSPSPNTWGPFPVRPVNPGN
TNSSPKHNNTSRLPNQNGTVLPSESAGLATASCPITVSSVVAASQQLCVTNTRTPSSV
RKQLFACVPKTSPPATVISSVTSTCSSLPSVSSAPITSGQAPTTFLPASTSQAQLSSQ
KMESFSAVPPTKEKVSTQDQPMANLCTPSSTANSCSSSASNTPGAPETHPSSSPTPTS
SNTQEEAQPSSVSDLSPMSMPFASNSEPAPLTLTSPRMVAADNQDTSNLPQLAVPAPR
VSHRMQPRGSFYSMVPNATIHQDPQSIFVTNPVTLTPPQGPPAAVQLSSAVNIMNGSQ
MHINPANKSLPPTFGPATLFNHFSSLFDSSQVPANQGWGDGPLSSRVATDASFTVQSA
FLGNSVLGHLENMHPDNSKAPGFRPPSQRVSTSPVGLPSIDPSGSSPSSSSAPLASFS
GIPGTRVFLQGPAPVGTPSFNRQHFSPHPWTSASNSSTSAPPTLGQPKGVSASQDRKI
PPPIGTERLARIRQGGSVAQAPAGTSFVAPVGHSGIWSFGVNAVSEGLSGWSQSVMGN
HPMHQQLSDPSTFSQHQPMERDDSGMVAPSNIFHQPMASGFVDFSKGLPISMYGGTII
PSHPQLADVPGGPLFNGLHNPDPAWNPMIKVIQNSTECTDAQQIWPGTWAPHIGNMHL
KYVN"
BASE COUNT 2386 a 1822 c 1878 g 2034 t
ORIGIN
1 gatcagcggc ggcggtgacc gcgagtgggt cggcaccgtc tccggctccg ggtgcgaaca
61 atgctgactg atagcggagg cggcggcacc tcctttgagg aggacctgga ctctgtggct
121 ccgcgatccg ccccagctgg ggcctcggag ccgcctccgc cgggaggggt cggtctgggg
181 atccgcaccg tgaggctctt tggggaggcc gggccagcgt cgggagtcgg cagcagcggc
241 ggcggcggca gcggcagcgg tacgggcgga ggggacgcgg cgctggattt caagttggcg
301 gctgccgtgc tgaggaccgg gggtggaggt ggtgcctctg gcagtgacga ggacgaagtg
361 tccgaggttg aatcatttat tttggaccaa gaagatctgg ataacccagt gcttaaaaca
421 acatcagaga tattcttatc aagtactgca gaaggagcag acttacgcac tgtggatcca
481 gagacacagg cacgactaga agcattgcta gaagcagcag gaattggcaa attgtcaact
541 gctgatggta aagcttttgc agatcctgag gtactccgga gactgacatc ctcagttagt
601 tgtgcactgg atgaagctgc tgctgcactg acacggatga aagcagaaaa cagccacaat
661 gcaggacaag tggacactcg cagtctagca gaagcttgtt cagatgggga tgttaatgct
721 gttcgtaaat tgctagatga aggcagaagt gtaaatgaac atacagaaga aggagaaagc
781 ctgctgtgtt tggcttgttc agcagggtat tatgaattag cacaagtatt gcttgctatg
841 catgctaatg ttgaagatcg agggaataaa ggagacataa ctcccctgat ggcagcttcc
901 agtggaggtt acttagatat tgtgaaatta ttacttcttc atgatgctga tgtcaactcc
961 cagtctgcaa caggaaacac tgcgctaact tatgcatgtg ctggaggatt tgttgacatt
1021 gttaaagtgc tccttaatga aggtgcaaat atagaagatc ataatgaaaa tggacatact
1081 cccttaatgg aagcagccag tgcaggtcat gtggaagttg caagagttct tttagatcat
1141 ggtgcaggca tcaacactca ttctaatgaa ttcaaagaaa gtgctctaac acttgcttgc
1201 tacaaaggcc atttggatat ggttcgcttt ctacttgaag ctggtgcaga tcaagagcac
1261 aaaacagatg agatgcacac tgccttaatg gaggcctgca tggatggaca tgtagaggtg
1321 gcacgtttgc ttttggatag tggtgctcaa gtgaacatgc ctgcagattc atttgaatct
1381 ccattgacgc tagctgcctg tggaggacat gttgaattgg cagctctact tattgaaagg
1441 ggagcaaatc ttgaagaagt taatgatgaa ggatacactc ccttgatgga agctgcccgg
1501 gaaggacatg aagaaatggt ggcactactc ttagcacaag gagcaaatat aaatgcccag
1561 acagaagaaa ctcaagaaac tgctcttact ttggcttgct gtggaggatt ttctgaagtt
1621 gcagactttc ttattaaggc aggggctgat atagaacttg gctgctccac acctctgatg
1681 gaggcatctc aggagggaca cctggaattg gttaaatatt tgctggcttc tggcgctaat
1741 gtgcatgcta caacagcaac aggagacaca gccttaacct atgcttgtga aaatggacat
1801 acggatgttg cagatgtttt acttcaagca ggggctgatt tagaacatga atctgaaggt
1861 ggaagaacac ctttgatgaa agctgcaaga gctggtcatt tgtgcactgt gcagtttctt
1921 attagcaaag gtgccaatgt taacagggct acagccaata atgatcatac agtagtgtcg
1981 ctggcatgtg caggaggcca cctggcagtt gttgagcttc tcttggctca tggggctgac
2041 cctactcatc gactcaagga tggttcaaca atgctcattg aagctgcaaa gggtggccat
2101 actaatgtag tttcttatct gttggattat ccaaataatg ttctgtcagt tcccaccaca
2161 gatgtgtctc agctccctcc accttctcaa gatcagtctc aggtgccacg tgtgccaacg
2221 catacacttg ccatggttgt acctccccag gaacctgaca gaacttcaca ggagaactct
2281 cctgcccttt taggagtgca aaaaggtaca tccaagcaga agtccagttc cctccaggta
2341 gcagatcagg acctactgcc atcttttcac ccataccagc ctttggagtg catagtagag
2401 gagactgaag gcaagctgaa tgaactggga caaagaatta gtgctattga aaaagcacag
2461 cttaagtcac tggagttaat tcaaggtgaa cctctgaaca aagataagat agaagaactt
2521 aaaaagaaca gagaagagca agtccagaag aagaagaaaa tattgaaaga actgcagaaa
2581 gtggaaaggc agttgcagat gaaaacacag cagcaattta ccaaagaata cttggaaacc
2641 aaaggtcaga aagacacagt gtctctacac caacagtgct ctcatagagg agtcttccca
2701 gaaggggaag gagatggtag tctcccagag gatcactttt cagagttacc tcaggttgac
2761 acaatcttat ttaaagataa tgatgttgat gatgagcaac agtctccacc atcggcagaa
2821 cagattgatt ttgtcccagt ccagccttta tcatctccac agtgtaactt ttccagtgac
2881 ttaggttcta atgggacaaa ttctcttgaa cttcagaaag tatcaggtaa tcaacagatt
2941 gtaggacagc ctcagattgc tattactgga catgatcagg ggctgttagt tcaagaacca
3001 gatggactaa tggttgcaac tccagctcag acgcttaccg acactcttga tgacctgata
3061 gcagctgtga gtaccagagt gcccactggt tccaacagtt cttctcagac cacagagtgt
3121 cttacacctg aatcctgttc gcagactaca agcaatgtgg cttcccaatc gatgcctcct
3181 gtgtatcctt cagttgacat tgatgcacat actgagagca atcatgacac agcattaaca
3241 ctagcttgtg caggtggtca tgaagaactt gtatctgtgc tcattgcacg ggatgccaaa
3301 attgaacaca gagacaaaaa aggtttcaca ccactaatcc tggcagcaac agcagggcat
3361 gttggagttg ttgaaatcct tttggataaa ggtggagata tagaagcaca gtctgaacga
3421 actaaggata ctccgctttc attggcatgt tctggtggac gtcaggaggt ggtagacttg
3481 ctgctggctc gaggtgcaaa taaagaacat aggaacgtat ctgattatac accactgagt
3541 ctagctgcgt ctggaggata tgttaatatc attaagattc tgcttaatgc tggggcagaa
3601 attaattcaa ggactgggag taaactaggt atttctcccc tgatgttggc tgcaatgaat
3661 ggacatgttc ctgcagtaaa attgctgctc gatatgggtt cagacattaa tgcccaaata
3721 gagaccaatc ggaacacggc tctcaccctg gcctgtttcc agggccgagc agaagtagtg
3781 agtttgcttc tggaccgaaa agccaatgtt gaacataggg caaagacggg tcttaccccc
3841 ttgatggaag cagcttctgg agggtatgca gaggttggaa gagttcttct tgataaagga
3901 gcagatgtta atgctccccc tgtgccttcc tcaagagata ctgctttaac aatagcagca
3961 gacaaaggtc actacaaatt ttgtgaactc ctgattcata ggggagccca cattgatgtt
4021 cgtaacaaaa agggaaatac gccactttgg ctggcatcca atggaggtca ttttgatgtt
4081 gtgcagttgc tagtgcaagc aggtgctgat gtggatgcag cagataaccg gaaaatcaca
4141 cctcttatgt cagcatttcg caagggtcat gtaaaagttg ttcaatattt ggtaaaggaa
4201 gtaaatcagt tcccttctga tatagaatgc atgagataca tagcaacaat tacagataag
4261 gaactgttga aaaaatgtca tcaatgtgtc gaaaccattg tgaaggctaa agaccagcaa
4321 gctgcagaag caaataagaa tgcgagtatt cttttaaagg aacttgatct ggaaaagtca
4381 agagaagaga gcagaaagca ggctcttgct gctaaaagag aaaaaagaaa agaaaagaga
4441 aaaaagaaaa aagaggaaca gaaaaggaaa caggaagaag atgaagaaaa caaacctaag
4501 gagaattcgg aactaccaga ggatgaagat gaagaggaga atgatgaaga tgtggagcaa
4561 gaagttccca tagaacctcc tagtgcaacc accaccacta cgattggaat ctctgcaaca
4621 tctgcaacat tcacaaatgt gtttgggaaa aaaagggcca atgtggtgac aactcccagc
4681 accaatcgga aaaataagaa gaacaaaaca aaagaaaccc ctcctacagc acatttaatt
4741 ttaccagaac aacatatgtc tttagcccaa caaaaggcag ataaaaataa aataaatgga
4801 gaacctagag gtggtggtgc aggtgggaat agtgattcag ataacttgga cagcacagac
4861 tgcaacagtg agagtagcag tggtggtaaa agccaagagt taaattttgt gatggatgtg
4921 aattcctcta aatacccctc actgctcctt cattcccaag aagaaaagac aagtactgct
4981 acttccaaaa ctcagacacg acttgaaggt gaagtgactc ctaattcctt gtcaaccagc
5041 tacaagacag tgtcattgcc attaagctct ccaaacataa agctgaatct cactagccct
5101 aaaaggggtc agaaaagaga agaagggtgg aaagaagttg tacgaaggtc aaagaaattg
5161 tctgttccag cctcagtggt gtcgaggata atgggaagag gaggatgcaa catcactgca
5221 atacaggatg ttactggtgc ccatattgat gtggataaac aaaaagataa gaatggcgag
5281 agaatgatca caataagggg tggcacagaa tcaacaagat atgcagttca actaatcaat
5341 gcactcattc aagatcctgc taaggaactg gaagacttga ttcctaaaaa tcatatcaga
5401 acacctgcca gcaccaaatc aattcatgct aacttctcat ctggagtagg taccacagca
5461 gcttccagta aaaatgcatt tcctttgggt gctccaactc ttgtaacttc acaggcaaca
5521 acgttatcta cgttccagcc cgctaataaa cttaataaga atgttccaac aaatgtacgt
5581 tcttctttcc cagtttctct acccttagct tatcctcacc ctcattttgc cctgctggct
5641 gctcaaacta tgcaacagat tcggcatcct cgcttaccca tggcccagtt tggaggaacc
5701 ttctcacctt ctcctaacac atggggacca ttcccagtga gacctgtgaa tcctggcaac
5761 acaaatagct ctccaaagca taataacaca agccgtctac ctaaccagaa cgggactgtt
5821 ttaccctcag agtctgctgg actagctact gccagttgtc ctatcactgt ctcttctgta
5881 gttgctgcca gtcagcaact gtgtgtcact aatacccgga ctccttcatc agtcagaaag
5941 cagttgtttg cctgtgtgcc taagacaagt cctccagcaa cagtgatttc ttctgtgaca
6001 agcacttgta gttccctgcc ttctgtctcc tctgcaccta tcactagcgg gcaagctccc
6061 accacatttc tacctgcaag tacttctcaa gcacagcttt cttcacaaaa gatggagtct
6121 ttctctgctg tgccacccac caaagagaaa gtgtccacac aggaccagcc catggcaaac
6181 ctatgtaccc catcttcaac tgcaaacagt tgcagtagct ctgccagcaa caccccggga
6241 gctccagaaa ctcacccatc cagtagtccc actcctactt ccagtaacac acaagaggag
6301 gcacagccat ccagtgtgtc tgatttaagt cctatgtcaa tgccttttgc atctaactca
6361 gaacctgctc cattgacttt gacatcaccc agaatggttg ctgctgataa tcaggacacc
6421 agtaatttac ctcagttagc tgtaccagca cctcgagttt ctcatcgaat gcagcccaga
6481 ggttcttttt actccatggt accaaatgca actattcacc aggatcccca gtctattttt
6541 gttacgaatc cagttacttt aacaccacct caaggcccac cagctgcagt gcagctttct
6601 tcagctgtga acattatgaa tggttctcag atgcacataa acccagcaaa taagtctttg
6661 ccacctacat ttggcccagc cacacttttc aatcacttca gcagtctttt tgatagtagt
6721 caggtgccag ctaaccaggg ctggggagat ggtccactgt cctcacgagt tgctacagat
6781 gcctctttca ctgttcagtc agcgttcctg ggtaactcag tgcttggaca cttggaaaac
6841 atgcaccctg ataactcaaa ggcacctggc ttcagaccac cttcccagcg agtttctact
6901 agtccagttg ggttaccatc cattgaccca tcaggcagct ccccatcttc ctcttctgct
6961 cctctggcaa gtttttccgg cataccagga acaagggttt tcctgcaagg gccagctcct
7021 gttgggactc ctagtttcaa cagacaacat ttttctcccc atccttggac aagcgcctca
7081 aactcatcca cttctgcccc accaacgttg ggccaaccaa aaggagtcag tgccagtcaa
7141 gatcgaaaga tacctccccc aattggaaca gagagactgg cccgaattcg gcaaggaggg
7201 tctgttgcac aagccccggc ggggaccagt tttgtcgctc ccgttggaca cagtggaatc
7261 tggtcatttg gtgtcaatgc tgtgtcagaa ggcttatcag gttggtcgca atctgtgatg
7321 gggaaccatc caatgcatca acaattatca gacccaagca cattctccca acatcagcca
7381 atggagagag atgattctgg aatggtagcc ccctctaaca tttttcatca gcctatggca
7441 agtggttttg tggatttttc taaaggtctg ccaatttcca tgtatggagg caccataata
7501 ccctctcatc ctcagcttgc tgatgttcca ggaggccctc tgtttaatgg acttcacaat
7561 ccagatcctg cttggaaccc tatgataaaa gttatccaaa attcaactga atgcactgat
7621 gcccagcaga tttggcctgg cacgtgggca cctcatattg gaaacatgca tctcaaatat
7681 gtcaactaag ttagaaggtc tttactcttt agccttgttt aagaaaccta tgaccttgga
7741 agaaccatgg ggattttttt ttaatgtgcc taagaaattt tctctgaggc tttagcaatg
7801 gaaatttgat tgcccattgt ataagaacaa attgatttcc tatccacctg attatgttct
7861 ctggttagtt tagccatttt gaacttaaga tcatatgacc ttagtgcttt tggctaaaca
7921 tacagaatac tacttgtatg cagaagagaa ttagttgatt acatgtttca accttttagg
7981 gtgataaata catgtataat tgtttacata cttaaaagga aaaagttgag taaatttctt
8041 gtcatatagt ggctctacgt aatgtagcct gtattaatgt gaaatattta ccagaatatt
8101 caataaaaag atgaacagtc
//