LOCUS AF520704 4467 bp mRNA linear HUM 09-DEC-2002
DEFINITION Homo sapiens K-dependent Na/Ca exchanger NCKX4 (SLC24A4) mRNA,
complete cds; alternatively spliced.
ACCESSION AF520704
VERSION AF520704.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4467)
AUTHORS Li,X.F., Kraev,A.S. and Lytton,J.
TITLE Molecular cloning of a fourth member of the potassium-dependent
sodium-calcium exchanger gene family, NCKX4
JOURNAL J. Biol. Chem. 277 (50), 48410-48417 (2002)
PUBMED 12379639
REFERENCE 2 (bases 1 to 4467)
AUTHORS Li,X.-F., Kraev,A.S. and Lytton,J.
TITLE Direct Submission
JOURNAL Submitted (11-JUN-2002) Biochem & Mol Biol, University of Calgary,
3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada
FEATURES Location/Qualifiers
source 1..4467
/db_xref="H-InvDB:HIT000081154"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..4467
/gene="SLC24A4"
exon 1..103
/gene="SLC24A4"
/number=1B
CDS 25..1842
/gene="SLC24A4"
/note="alternatively spliced"
/codon_start=1
/product="K-dependent Na/Ca exchanger NCKX4"
/protein_id="AAM76070.1"
/translation="MLPQQVGFVCAVLALVCCASGLFGSLGHKTASASKRVLPDTWRN
RKLMAPVNGTQTAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCD
DFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSA
VFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLI
ILYVFYILIMKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQ
VKEKPQYGKNPVVMVDEIMSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINER
QRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEA
DFLSPFSVPEARGDKVKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVF
SYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGS
NVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRL
DRKLGVYVLVLYAIFLCFSIMIEFNVFTFVNLPMCREDD"
exon 104..214
/gene="SLC24A4"
/number=2
exon 215..291
/gene="SLC24A4"
/number=3
exon 292..366
/gene="SLC24A4"
/number=4
exon 367..451
/gene="SLC24A4"
/number=5
exon 452..555
/gene="SLC24A4"
/number=6
exon 556..630
/gene="SLC24A4"
/number=7
exon 631..656
/gene="SLC24A4"
/number=8
exon 657..710
/gene="SLC24A4"
/number=9
exon 711..853
/gene="SLC24A4"
/number=10A
exon 854..1023
/gene="SLC24A4"
/number=11
exon 1024..1228
/gene="SLC24A4"
/number=12
exon 1229..1395
/gene="SLC24A4"
/number=13
exon 1396..1510
/gene="SLC24A4"
/number=14
exon 1511..1623
/gene="SLC24A4"
/number=15
exon 1624..1689
/gene="SLC24A4"
/number=16
exon 1690..4467
/gene="SLC24A4"
/number=17
BASE COUNT 1115 a 1051 c 1076 g 1224 t
ORIGIN
1 ctcaaagttc gcaggaggcg agagatgctg ccgcagcaag tcggcttcgt gtgcgcggtg
61 ctggccctgg tgtgctgtgc gtccggcctc ttcggcagct tggggcacaa aacagcttct
121 gctagcaaac gtgtcctgcc agacacatgg agaaatagaa agttgatggc cccagtgaat
181 gggacacaga cagccaagaa ctgcacagat cctgcgattc acgagttccc cacagatctg
241 ttctccaata aggagcgaca gcacggagcc gtcctgctgc acatccttgg tgctctgtat
301 atgttctatg ccttggccat agtgtgcgat gacttctttg ttccgtctct agagaagatc
361 tgtgagagac tccatctgag cgaagatgtg gctggagcca ccttcatggc tgcaggaagc
421 tcaacgccag agctgtttgc gtctgttatt ggggtgttca tcacccatgg ggacgtcggg
481 gtgggcacca tcgtgggctc tgctgtgttc aacatcctgt gcataattgg agtgtgcgga
541 ctgtttgctg gccaggtggt ccgtctgacg tggtgggccg tgtgccgaga ctccgtgtac
601 tacaccatct ctgtcatcgt gctcatcgtg ttcatatatg atgaacaaat tgtgtggtgg
661 gaaggcctgg tgctcatcat cttgtatgtg ttttatattc tgatcatgaa gtacaatgtg
721 aagatgcaag cctttttcac agtcaaacaa aagagcattg caaacggtaa cccggtcaac
781 agtgagctgg aggctggtaa tgatttctat gacggtagct atgatgaccc ttccgtgcca
841 ttgctggggc aagtgaagga gaagccacag tatggcaaga accccgtggt gatggtggac
901 gagattatga gctccagccc tcccaagttc accttccctg aagcaggctt acgaatcatg
961 atcaccaata agtttggacc caggacccga ctacggatgg ccagcaggat catcattaat
1021 gagcggcaga gactgatcaa ctcggccaat ggtgtgagca gtaagccgct tcaaaacggg
1081 aggcacgaga acattgagaa cgggaatgtt cctgtggaaa accccgaaga ccctcagcag
1141 aatcaggagc agcagccgcc gccacagcca ccaccgccag agccagagcc ggtggaggct
1201 gacttcctgt cccccttctc cgtgccggag gccagagggg acaaggtcaa gtgggtgttc
1261 acctggcccc tcatcttcct cctgtgcgtc accattccca actgcagcaa gccccgctgg
1321 gagaagttct tcatggtcac cttcatcacc gccacgctgt ggatcgctgt gttctcctac
1381 atcatggtgt ggctggtgac tattatcgga tacacacttg ggatcccgga tgtcatcatg
1441 ggcattactt tcctggcagc agggacaagt gttccagact gcatggccag cctaattgtg
1501 gcgagacaag gccttgggga catggcagtc tccaacacca taggaagcaa cgtgtttgac
1561 atcctggtag gacttggtgt accgtggggc ctgcagacca tggttgttaa ttatggatca
1621 acagtgaaga tcaacagccg ggggctggtc tattccgtgg tcctgttgct gggctctgtc
1681 gctctcaccg tcctcggcat ccacctaaac aagtggcgac tggaccggaa gctgggtgtc
1741 tacgtgctgg ttctctacgc catcttcttg tgcttctcca taatgataga gtttaacgtc
1801 tttaccttcg tcaacttgcc gatgtgccgg gaagacgatt agcgctgagt cgcggcccct
1861 gggagctgat ctggacaccc tgtgacactg gcgttctcct ctcccctcct tcccccacca
1921 caggtctctc ctgcataggc agccactgtc cgttctttca cacactggaa ggaagagcca
1981 tcgtggtctt tgtctggcca caggccaggc tgctgggcat cctcctcctc cttggagttc
2041 cgcccctgca aggctggatt tgggggccat tatctgagca gcttcaaaga cccctgagct
2101 gccaaccacg gagatgtgcc aagcatctca tctctcctgc acactttagt cagaaggact
2161 tctgcatgca gtttgtcttt ctgttctgca ggcagcttca gaattgaggt catttgtgag
2221 cacaagatct catagggcag gtgcaaaata ggaatgttgt tctcaagtgt cacctccagc
2281 ccagaggtgg ttccttaggc agcatgtgct cctgggagcc tctgactttt gctggaagca
2341 gccacagttt ggaaggggca agacctcaac ctgttggggt ttagggccca tgatggcaga
2401 cattctaccc cttttcctgg aaaaactgga agaatgaaaa taattttttt ctgtggaaga
2461 gagaaaatga gtgaatattc ttctcacttt tattgatgca ttcagagaat aagcaatgaa
2521 atattaaaaa atgaaacatc atataggtca tcatacttga aaattatcat tccatatgaa
2581 aggatcatga tacacaccaa aaaagtaatg atcgtaaaga cacaaatcct ctgtatgcca
2641 tcttgcattg gcactgaggt gtttggtttg gaatagggaa aaaggtaaga gactaacgtg
2701 gaaaggtgct aactcagaga ctggagatta tagtttacag ctgtactttc cagatcttct
2761 atgtgacaca atgcactgtc cttgtgggtt tgtcatttat tggttaatgc tctagtttca
2821 aaaccaccct gttgaaagtt ccagttattt atatgcccaa caaatttcat agcctgctga
2881 actgaactga gtgtgtcaga agtgctggtt aatgacgaga agagattgcc tgaaaaacaa
2941 caaactgctt tctggttagc tgaaggcaag tgtgaaaatc agaatttaga atatttagag
3001 ctaagcttct ggaaccacgt agtttctaca cgtggcaggc caagaatggg aggctgactc
3061 aaaactagat agaaaaatat aaaataatct tcgaccactt gatagctctc aaatatatat
3121 ttaaaagatt tatgaataca aaccatttat ggtttatgat ttctaaaaag aaagcacaat
3181 taattttata gagaggtttt ttattttttt aatatttcta ttgcaaaagt ctatccgatt
3241 tgatgcactt tgaatattga gatattttgc acggatgaat gtatgggaac tacccatgat
3301 gatgtaagag gaaagaacat ttttttgtga ttcaccagac atcactttaa acttggtgat
3361 gagtttaaat ccagtagcta atcccttcct gagactcaaa gatcgtgacg ctggttggaa
3421 tttctgactg tgccctttag ggcctcctgg agtttcaaaa ggaggaagtg ttcngtgctt
3481 gtgtccctga agttccctgt tgcatgagcc tgcgacagga cctcaccccc accaccaggc
3541 ttctatttgg gattcacatc agtattagta tcgtagctac accaagttca ggcttctctt
3601 tttgtttttt tacctagaaa ttgggctcag tggtcttcaa cttgaggacg agggtgattt
3661 tcctaagaaa tcagcaaaga gggaaggcag ggcccctgta gattcaccag tataaacttc
3721 agctgcaggg attccagagc cctcgggacc actctgtcac cttaatagcc aagttctcct
3781 ggttcctccg atcttacagg ctcatccagg ttccaaagtg cttctgtctc tgttttgatt
3841 ctccaaactg ctctgtgatg tatgtaggga ttattctccc cacttaacag aaagtagtgt
3901 cttggagagg tcaagggtct ctagttcaat ggccagtcat agcagaaggg aggccaagca
3961 ccagtccatc acccctccca ggccagcctc tgtaagttgg ccacacttgg ggagtgagtg
4021 tgggtatgac tttaccctcc tggttggttc ttactgtttg agtcaaaacc tcatcaatat
4081 atcattgact cctgggttcc tcaggtcatt tcctaatatc tgtccctatc caatgcctct
4141 attttatctt gaaaaaagga ccaaaaatta tttttagcta tggcaaggca caggccacat
4201 ggcccctgat ggcgtccctg ctggttttca attctctgaa gccttgtgta gctttcagag
4261 cacacgtatc ctaattaccc tcctcttcct cagcagaacc catttgagat tctaaatgaa
4321 tactcttagt ctctaaagtt gcagttagaa actaaaataa tgttttttaa tatgtaatat
4381 gctcctcttg gctaattttc ttttgacttt aatgtgccaa tgtaacttcc tttaaaggat
4441 ctatgcattt attaaatctg gaaaact
//