LOCUS AF520614 2274 bp mRNA linear HUM 07-JUL-2002
DEFINITION Homo sapiens partner of PIX 1 (POPX1) mRNA, complete cds.
ACCESSION AF520614
VERSION AF520614.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2274)
AUTHORS Koh,C.G., Tan,E.J., Manser,E. and Lim,L.
TITLE The p21-activated kinase PAK is negatively regulated by POPX1 and
POPX2, a pair of serine/threonine phosphatases of the PP2C family
JOURNAL Curr. Biol. 12 (4), 317-321 (2002)
PUBMED 11864573
REFERENCE 2 (bases 1 to 2274)
AUTHORS Koh,C.G., Tan,E.J., Manser,E. and Lim,L.
TITLE Direct Submission
JOURNAL Submitted (07-JUN-2002) Glaxo, Institute of Molecular and Cell
Biology, 30 Medical Drive, Singapore 117609, Singapore
FEATURES Location/Qualifiers
source 1..2274
/db_xref="H-InvDB:HIT000081151"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
gene 1..2274
/gene="POPX1"
CDS 1..2274
/gene="POPX1"
/note="protein phosphatase; POPX1"
/codon_start=1
/product="partner of PIX 1"
/protein_id="AAM76058.1"
/translation="MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPEPEPEPEPE
PESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPEEEAAVEGEEEEE
GAATAAAAPGHSAVPPPPPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCP
SFLAAALARATSDEVLQSDLSAHYIPKETDGTEGTVEIETVKLARSVFSKLHEICCSW
VKDFPLRRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDG
HGGVDAAIYASIHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTG
VVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGA
WRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVK
VVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTEN
SFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVL
EDPGYLDLTQIEASKPHSAQFLLPVEMFGPGAPKKANLINELMMEKKSVQSSLPEWSG
AGEFPTAFNLGSTGEQIYRMQSLSPVCSGLENEQFKSPGNRVSRLSHLRHHYSKKWHR
FRFNPKFYSFLSAQEPSHKIGTSLSSLTGSGKRNRIRSSLPWRQNSWKGYSENMRKLR
KTHDIPCPDLPWSYKIE"
misc_feature 460..807
/gene="POPX1"
/note="Region: PIX interacting region"
misc_feature 667..1455
/gene="POPX1"
/note="Region: PP2C domain"
BASE COUNT 598 a 539 c 650 g 487 t
ORIGIN
1 atggccggct gcatccctga ggagaaaact taccggcgct tcctggagct attcctgggc
61 gagtttcgcg gaccgtgcgg cggcggcgag ccggagccgg aacccgaacc cgaacccgaa
121 cccgaacccg aacccgagtc cgagcccgag cccgaacctg aactggtaga agctgaggcg
181 gccgaggctt cggtagagga acccggggag gaggcggcca cggtagccgc gacggaggag
241 ggggaccagg agcaagaccc ggagcccgag gaggaggcgg cggttgaggg tgaggaggag
301 gaggagggcg cggcgacggc ggcggcagcc ccggggcact cggccgtgcc gccgccgccg
361 ccccagctgc cgcctttgcc cccgctcccg cgaccgctgt cagagcgcat cacccgcgag
421 gaggtggagg gcgaaagcct ggacctgtgc ctgcagcagc tctacaaata taattgccct
481 tcctttttgg ctgctgcttt agccagagcc acatcagatg aagtccttca gagtgatctt
541 tctgcacatt atatcccaaa ggaaacggat ggcacagaag ggactgtgga gattgagaca
601 gtgaaattgg cccgttctgt cttcagcaaa ctacacgaga tttgctgcag ctgggtgaaa
661 gacttccccc tccgcaggag accccagctt tattatgaga catcaatcca tgccatcaaa
721 aacatgcgca ggaaaatgga ggacaaacat gtctgcattc ctgactttaa tatgctcttc
781 aacctagagg accaggaaga acaagcttac tttgcagtgt ttgatggcca tgggggagta
841 gatgctgcta tttatgcctc cattcacctc cacgttaact tagtccgcca ggagatgttc
901 ccccatgatc ctgctgaggc cctgtgcagg gccttccggg tcactgatga gcggtttgtg
961 cagaaagcag ccagggagag cttaagatgt gggaccacag gagtggtgac tttcatcaga
1021 ggcaacatgc tacatgtggc ctgggtgggt gattcccagg ttatgcttgt gagaaagggc
1081 caagctgttg aactaatgaa gccacacaaa ccagacagag aggatgaaaa gcagagaatt
1141 gaggcccttg gaggttgcgt agtctggttt ggtgcctgga gggtgaatgg aagtctgtcg
1201 gtttccagag ctattggaga tgctgaacat aagccatata tctgtgggga tgcagattct
1261 gcctccactg ttctggatgg gaccgaagac tacctcattc tggcctgtga tggcttctat
1321 gacaccgtga accctgatga ggcagtgaaa gttgtgtccg accacctgaa agagaataat
1381 ggagacagca gcatggttgc ccacaaatta gtggcatcag ctcgtgatgc tgggtcaagt
1441 gataacatca cggttattgt ggtattcctg agggacatga acaaagctgt aaatgttagt
1501 gaggaatcag attggacaga gaactctttt caaggagggc aagaagatgg tggggatgat
1561 aaggagaatc atggagagtg caaacgccct tggcctcagc accagtgctc agcaccagcc
1621 gacctaggct atgatgggcg tgtggattca ttcactgata gaactagcct gagcccaggg
1681 tcccaaatca acgtgctgga agacccaggc tacctagatc tcacacaaat agaagcaagc
1741 aaacctcaca gtgcccagtt tttgctacca gttgagatgt ttggtcctgg tgcaccaaag
1801 aaagcaaatc ttattaatga gttaatgatg gagaaaaaat cagttcagtc atcattgcct
1861 gaatggagtg gtgctggaga gtttcccact gctttcaatt tgggttcaac aggggagcag
1921 atatacagaa tgcagagctt gtctcctgtc tgttcagggt tggaaaatga acagttcaaa
1981 tccccgggaa acagagtttc tagattgtct catttacgcc accactactc aaagaagtgg
2041 cacagattca ggtttaatcc aaagttttat tcatttctct ctgctcaaga gccttcccac
2101 aaaataggca ctagcctgtc ctcacttact ggaagtggga agagaaatag gataagaagt
2161 tctctgccat ggaggcaaaa tagttggaaa gggtacagtg aaaacatgag gaagctcaga
2221 aagactcatg atattccatg cccagatctt ccttggagct ataaaataga ataa
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