LOCUS AF516695 4604 bp mRNA linear HUM 10-SEP-2002
DEFINITION Homo sapiens voltage-gated calcium channel alpha(2)delta-4 subunit
mRNA, complete cds.
ACCESSION AF516695
VERSION AF516695.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4604)
AUTHORS Qin,N., Yagel,S., Momplaisir,M.L., Codd,E.E. and D'Andrea,M.R.
TITLE Molecular cloning and characterization of the human voltage-gated
calcium channel alpha(2)delta-4 subunit
JOURNAL Mol. Pharmacol. 62 (3), 485-496 (2002)
PUBMED 12181424
REFERENCE 2 (bases 1 to 4604)
AUTHORS Qin,N., Yagel,S., Momplaisir,M.L., Codd,E.E. and D'Andrea,M.R.
TITLE Direct Submission
JOURNAL Submitted (29-MAY-2002) Drug Discovery, Johnson & Johnson
Pharmaceutical Research and Development L.L.C., McKean & Welsh
Roads, Spring House, PA 19477, USA
FEATURES Location/Qualifiers
source 1..4604
/db_xref="H-InvDB:HIT000081120"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12p13.3"
CDS 415..3777
/note="channel regulatory subunit"
/codon_start=1
/product="voltage-gated calcium channel alpha(2)delta-4
subunit"
/protein_id="AAN06672.1"
/translation="MPATPNFLANPSSSSRWIPLQPMPVAWAFVQKTSALLWLLLLGT
SLSPAWGQAKIPLETVKLWADTFGGDLYNTVTKYSGSLLLQKKYKDVESSLKIEEVDG
LELVRKFSEDMENMLRRKVEAVQNLVEAAEEADLNHEFNESLVFDYYNSVLINERDEK
GNFVELGAEFLLESNAHFSNLPVNTSISSVQLPTNVYNKDPDILNGVYMSEALNAVFV
ENFQRDPTLTWQYFGSATGFFRIYPGIKWTPDENGVITFDCRNRGWYIQAATSPKDIV
ILVDVSGSMKGLRMTIAKHTITTILDTLGENDFVNIIAYNDYVHYIEPCFKGILVQAD
RDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCNQAIMLISDGAVE
DYEPVFEKYNWPDCKVRVFTYLIGREVSFADRMKWIACNNKGYYTQISTLADTQENVM
EYLHVLSRPMVINHDHDIIWTEAYMDSKLLSSQAQSLTLLTTVAMPVFSKKNETRSHG
ILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHPDLRPLYREGKKLKPK
PNYNSVDLSEVEWEDQAESLRTAMINRETGTLSMDVKVPMDKGKRVLFLTNDYFFTDI
SDTPFSLGAVLSRGHGEYILLGNTSVEEGLHDLLHPDLALAGDWIYCITDIDPDHRKL
SQLEAMIRFLTRKDPDLECDEELVREVLFDAVVTAPMEAYWTALALNMSEESEHVVDM
AFLGTRAGLLRSSLFVGSEKVSDRKFLTPEDEASVFTLDRFPLWYRQASEHPAGSFVF
NLRWAEGPESAGEPMVVTASTAVAVTVDKRTAIAAAAGVQMKLEFLQRKFWAATRQCS
TVDGPYTQSCEDSDLDCFVIDNNGFILISKRSRETGRFLGEVDGAVLTQLLSMGVFSQ
VTMYDYQAMCKPSSHHHSAAQPLVSPISAFLTATRWLLQELVLFLLEWSVWGSWYDRG
AEAKSVFHHSHKHKKQDPLQPCDTEYPVFVYQPAIREANGIVECGPCQKVFVVQQIPN
SNLLLLVTDPTCDCSIFPPVLQEATEVKYNASVKCDRMRSQKLRRRPDSCHAFHPEEN
AQDCGGASDTSASPPLLLLPVCAWGLLPQLLR"
BASE COUNT 1094 a 1288 c 1297 g 925 t
ORIGIN
1 cacaggaacg gggctgcctc tttaaagcag aggggtgcac tatagccctg agggaaccag
61 ctgcagttgt ggtaatcttg ggaggcagct ccccaccccc tgccaccccc tccctgctgt
121 caggagagga ttagaggaga ggccagcgga ttaaagggtt tcatgttgcc acagcctctc
181 ccccagtccc tgtctccgag gcctgcttgc taggtggggc gactcttctg tgagctgcag
241 ctgtggggca gagagaagcc ctccccaccc aggactgaga ggctggagac cccaggctcg
301 ccaaggcacg gaagacaaag gcctggggcg tcctggggtc tgggaggaag gcagacagag
361 ctcatggtct gtggctgctc tgccctcctt cccctcccca accccaggcc caccatgcct
421 gcaactccca acttcctcgc aaaccccagc tccagcagcc gctggattcc cctccagcca
481 atgcccgtgg cctgggcctt tgtgcagaag acctcggccc tcctgtggct gctgcttcta
541 ggcacctccc tgtcccctgc gtggggacag gccaagattc ctctggaaac agtgaagcta
601 tgggctgaca ccttcggcgg ggacctgtat aacactgtga ccaaatactc aggctctctc
661 ttgctgcaga agaagtacaa ggatgtggag tccagtctga agatcgagga ggtggatggc
721 ttggagctgg tgaggaagtt ctcagaggac atggagaaca tgctgcggag gaaagtcgag
781 gcggtccaga atctggtgga agctgccgag gaggccgacc tgaaccacga attcaatgaa
841 tccctggtgt tcgactatta caactcggtc ctgatcaacg agagggacga gaagggcaac
901 ttcgtggagc tgggcgccga gttcctcctg gagtccaatg ctcacttcag caacctgccg
961 gtgaacacct ccatcagcag cgtgcagctg cccaccaacg tgtacaacaa agacccagat
1021 attttaaatg gagtctacat gtctgaagcc ttgaatgctg tcttcgtgga gaacttccag
1081 agagacccaa cgttgacctg gcaatatttt ggcagtgcaa ctggattctt caggatctat
1141 ccaggtataa aatggacacc tgatgagaat ggagtcatta cttttgactg ccgaaaccgc
1201 ggctggtaca ttcaagctgc tacttctccc aaggacatag tgattttggt ggacgtgagc
1261 ggcagtatga aggggctgag gatgactatt gccaagcaca ccatcaccac catcttggac
1321 accctggggg agaatgactt cgttaatatc atagcgtaca atgactacgt ccattacatc
1381 gagccttgtt ttaaagggat cctcgtccag gcggaccgag acaatcgaga gcatttcaaa
1441 ctgctggtgg aggagttgat ggtcaaaggt gtgggggtcg tggaccaagc cctgagagaa
1501 gccttccaga tcctgaagca gttccaagag gccaagcaag gaagcctctg caaccaggcc
1561 atcatgctca tcagcgacgg cgccgtggag gactacgagc cggtgtttga gaagtataac
1621 tggccagact gtaaggtccg agttttcact tacctcattg ggagagaagt gtcttttgct
1681 gaccgcatga agtggattgc atgcaacaac aaaggctact acacgcagat ctcaacgctg
1741 gcggacaccc aggagaacgt gatggaatac ctgcacgtgc tcagccgccc catggtcatc
1801 aaccacgacc acgacatcat ctggacagag gcctacatgg acagcaagct cctcagctcg
1861 caggctcaga gcctgacact gctcaccact gtggccatgc cagtcttcag caagaagaac
1921 gaaacgcgat cccatggcat tctcctgggt gtggtgggct cagatgtggc cctgagagag
1981 ctgatgaagc tggcgccccg gtacaagctt ggagtgcacg gatacgcctt tctgaacacc
2041 aacaatggct acatcctctc ccatcccgac ctccggcccc tgtacagaga ggggaagaaa
2101 ctaaaaccca aacctaacta caacagtgtg gatctctccg aagtggagtg ggaagaccag
2161 gctgaatctc tgagaacagc catgatcaat agggaaacag gtactctctc gatggatgtg
2221 aaggttccga tggataaagg gaagcgagtt cttttcctga ccaatgacta cttcttcacg
2281 gacatcagcg acaccccttt cagtttgggg gcggtgctgt cccggggcca cggagaatac
2341 atccttctgg ggaacacgtc tgtggaagaa ggcctgcatg acttgcttca cccagacctg
2401 gccctggccg gtgactggat ctactgcatc acagatattg acccagacca ccggaagctc
2461 agccagctag aggccatgat ccgcttcctc accaggaagg acccagacct ggagtgtgac
2521 gaggagctgg tccgggaggt gctgtttgac gcggtggtga cagcccccat ggaagcctac
2581 tggacagcgc tggccctcaa catgtccgag gagtctgaac acgtggtgga catggccttc
2641 ctgggcaccc gggctggcct cctgagaagc agcttgttcg tgggctccga gaaggtctcc
2701 gacaggaagt tcctgacacc tgaggacgag gccagcgtgt tcaccctgga ccgcttcccg
2761 ctgtggtacc gccaggcctc agagcatcct gctggcagct tcgtcttcaa cctccgctgg
2821 gcagaaggac cagaaagtgc gggtgaaccc atggtggtga cggcaagcac agctgtggcg
2881 gtgaccgtgg acaagaggac agccattgct gcagccgcgg gcgtccaaat gaagctggaa
2941 ttcctccagc gcaaattctg ggcggcaacg cggcagtgca gcactgtgga tgggccgtac
3001 acacagagct gcgaggacag tgatctggac tgcttcgtca tcgacaacaa cgggttcatt
3061 ctgatctcca agaggtcccg agagacggga agatttctgg gggaggtgga tggtgctgtc
3121 ctgacccagc tgctcagcat gggggtgttc agccaagtga ctatgtatga ctatcaggcc
3181 atgtgcaaac cctcgagtca ccaccacagt gcagcccagc ccctggtcag cccaatttct
3241 gccttcttga cggcgaccag gtggctgctg caggagctgg tgctgttcct gctggagtgg
3301 agtgtctggg gctcctggta cgacagaggg gccgaggcca aaagtgtctt ccatcactcc
3361 cacaaacaca agaagcagga cccgctgcag ccctgcgaca cggagtaccc cgtgttcgtg
3421 taccagccgg ccatccggga ggccaacggg atcgtggagt gcgggccctg ccagaaggta
3481 tttgtggtgc agcagattcc caacagtaac ctcctcctcc tggtgacaga ccccacctgt
3541 gactgcagca tcttcccacc agtgctgcag gaggcgacag aagtcaaata taatgcctct
3601 gtcaaatgtg accggatgcg ctcccagaag ctccgccggc gaccagactc ctgccacgcc
3661 ttccatccag aggagaatgc ccaggactgc ggcggcgcct cggacacctc agcctcgccg
3721 cccctactcc tgctgcctgt gtgtgcctgg gggctactgc cccaactcct gcggtgacac
3781 cacccagcct gacctgtgtt ttggcaaggt gatccttcca gagccatccc aaaaagtcag
3841 cactgacatg ggatgcagct aactgcagtt gggtcgcccc caggccaacg ctcctctcaa
3901 tcctgggctg gtggcccctg gctccggaga atgctggatg gaacaggaaa ccaatcacct
3961 ggcaccactt tcaagatgct tcatggtgcc cggtaccatc tgccctaggt ctcaacatga
4021 gcatacttct gacctaacct tcctgtctcc tcttcgggaa gccagcgtga gctcagcttg
4081 gaccaagaca aaataattta gttcttcctg tactccagag tccagaccca gccaagaaag
4141 ggtcagttgt ttctgaccct ttctgtcgga gtggtctctg gtagaaccca aggacttctg
4201 ggtactgaga agcagcagca gaatgaggcc aaatgcagag atgaggctaa ggcaagaata
4261 tgccccaact aaagcataga ttccccaaag tgaggctcat ggtgggaggc cactcacctt
4321 cctagctgct gctcgaaaag gttttgactg tgttggggtg ggggttgggt aagggaatgg
4381 tcaagactga gaaaggaatg aaatccattc aggaaatatc gacagggcta cacgtgatgt
4441 ccccaaactg ctgctattga agaacttccc aaaacttctt tacaaagccc taaaggaaag
4501 tttgcatcta tgaaaagcca ataggctgag acatccaatt gctgcatgga aattgatgta
4561 cattcagggg acggcaaaaa tagctgtaaa agtgaaaaaa aaaa
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